Medicament composition for curing mouth ulcer
A technology for oral ulcers and compositions, which is applied in the field of pharmaceutical compositions for the treatment of oral ulcers in humans or mammals, can solve the problems of accelerated ulcer healing, chronic toxicity, easy to produce systemic side effects, etc. Effect
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Embodiment 1
[0040] paste sheet
[0041] Dexamethasone acetate 0.3g
[0042] Vitamin B 12 0.05g
[0043] Carbomer 10g
[0044] Dextrin 30g
[0045] Magnesium stearate 0.03g
[0046] The protective layer
[0047] 100-55 4g
[0048] Titanium dioxide 1g
[0049] Yellow Iron Oxide 1g
[0050] Acetyl tributyl citrate (ATBC) 0.8g
[0051] Preparation Process:
[0052] Dissolve dexamethasone acetate with 5ml absolute ethanol, and vitamin B 12 Add 5ml of purified water to dissolve, add the solution of the above active ingredients to the dextrin passed through a 100-mesh sieve, mix well, then granulate through a 30-mesh sieve, dry at 60°C, granulate through a 40-mesh sieve, add 100-mesh sieve Mesh sieved carbopol and magnesium stearate are fully mixed, and then compressed with a flat punch with a diameter of 6 mm to obtain 1000 tablets, containing 0.30 mg of dexamethasone acetate and vitamin B 12 0.05 mg. the prescribed amount Dissolve L 100-55 with 95ml of 95% ...
Embodiment 2
[0054] As in the formulation of Example 1, 2 g of lidocaine hydrochloride was added to the active ingredient and dissolved in an appropriate amount of purified water, and added separately with other active ingredients. Other preparation technology is with embodiment 1
Embodiment 3
[0056] paste sheet
[0057] Dexamethasone 1g
[0058] Vitamin B 12 0.1g
[0059] Carbomer 5g
[0060] Polyvinylpyrrolidone (PVP) 3g
[0061] Dextrin 30g
[0062] Magnesium stearate 0.05g
[0063] The protective layer
[0064] 100-55 4g
[0065] Titanium dioxide 0.5g
[0066] Tributyl citrate (TBC) 0.8g
[0067] Preparation Process:
[0068] Dissolve dexamethasone with 10ml absolute ethanol, and vitamin B 12 Add 5ml of purified water to dissolve, add the solution of the above active ingredients to the dextrin passed through a 100-mesh sieve, mix well, then granulate through a 30-mesh sieve, dry at 60°C, granulate through a 40-mesh sieve, add 100-mesh sieve Mesh sieved carbomer, PVP, and magnesium stearate are fully mixed, and pressed with a flat punch with a diameter of 6 mm to obtain 1,000 tablets, containing 1 mg of dexamethasone vitamin B 12 0.1 mg. the prescribed amount 100-55 was dissolved with 95ml of 95% ethanol, added TBC and titanium diox...
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