32 results about "Buccal ulcer" patented technology

Compositions and methods for treating, reducing, or preventing a disease or symptom such as gingivitis, periodontitis, gastritis, colitis, ileitis, Crohn's disease, chronic inflammatory intestinal disease, inflammatory bowel syndrome, chronic inflammatory bowel disease, celiac disease, ulcerative colitis, a gastric ulcer, a peptic ulcer, a buccal ulcer, a nasopharyngeal ulcer, an esophageal ulcer, a duodenal ulcer, a gastrointestinal ulcer, an autoimmune disorder, or pain. The method includes identifying a patient in need of treatment and administering a therapeutically effective amount of at least one cationic steroid antimicrobial (CSA), or a pharmaceutically acceptable salt thereof. Kits comprising such compositions and instructions on such methods are also contemplated herein.

The present invention discloses an application of nakedflower beautyberry leaf extract in oral cleaning product. The nakedflower beautyberry leaf extract which has efficacies of excellent antimicrobial effect, inflammation elimination, detoxication, hemostasis and convergence is taken as the additive of oral cleaning product, and is added into the oral cleaning products of chewing gum, toothpaste, gargle water, etc. The daily nursing of people to the oral cavity is greatly facilitated. The oral product comprising the nakedflower beautyberry leaf extract can effectively alleviate various symptoms of oral gum hemorrhage, gingivitis and mouth ulcer. Simultaneously the nakedflower beautyberry leaf extract also has excellent prevention function to the symptoms of oral gum hemorrhage, gingivitis and mouth ulcer.

The invention relates to a medicinal composition used for treating human or animal dental ulcer; the medicinal composition consists of an active component, dexamethasone, one or more medicinal salts or esters thereof, vitamin B12, and one or more medicinal inactive components that are suitable for local administration to the oral cavity.

The invention discloses a prepared traditional Chinese medicinal preparation for treating ulcerative stomatitis, wherein the active constituents include the following raw material herbs (by weight portion): astragalus root 15g, baikal skullcap root 10g, plaster stone 10g, root of pilose asiabell 10g, Chinese angelica root 10g, dried orange peel 10g, bupleurum root 6g, bamboo leaves 6g, cimicifuga rhizome 6g, wrinkled gianthyssop 10g, poria cocos wolf 10g, white atractylodes rhizome 15g, licorice root 6g. The medicament should be decocted in water for the oral dose.

Methods of treating, reducing, or preventing a disease or symptom relating to a disease such as oral mucositis, gingivitis, periodontitis, gastric mucositis, inflammatory fibrosis, gastritis, colitis, ileitis, Crohn's disease, chronic inflammatory intestinal disease, inflammatory bowel syndrome, chronic inflammatory bowel disease, celiac disease, ulcerative colitis, a gastric ulcer, a peptic ulcer, a buccal ulcer, a nasopharyngeal ulcer, an esophageal ulcer, a duodenal ulcer, a gastrointestinal ulcer, an autoimmune disorder, inflammation associated with cancer, cancer treatment, or radiation, and / or pain that include: identifying a patient in need of treatment; and administering a therapeutically effective amount of at least one cationic steroid antimicrobial (CSA), or a pharmaceutically acceptable salt thereof. Kits comprising such compositions and instructions on such methods are also contemplated herein.

The invention belongs to the technical field of medicines and discloses a medicament for treating dental ulcer of infants. Gentamycin sulfate chewable tablets, prednisone acetate tablets, vitamin C tablets and vitamin B complex tablets (each tablet comprises main components of 13mg of vitamin B, 21.5mg of vitamin B, 60.2mg of vitamin B, 10mg of niacinamide and 1mg of dextro calcium pantothenate ) are used as raw materials, are mixed in the ratio according to different characteristics of each medicinal raw material, are dried at low temperature, ground, evenly blended and sterilized and subjected to other treatments and are prepared into western medicine powder or a spraying agent. The invention has the characteristics of new formula, simple manufacture and remarkable effect; and raw materials for preparing medicaments have wide source and low price, so the cost of medicinal products is reduced. Used by 120 infants suffered from infant dental ulcer, the total effective rate reaches 100 percent and special toxic and side effects are not found.

The invention provides a compound buccal tablet containing sodium azulene sulfonate and an application. The compound buccal tablet containing the sodium azulene sulfonate comprises the following components by weight percent: 0.2 to 1 percent of sodium azulene sulfonate, 80 to 89 percent of dedicated Chinese herbal medicinal extract, 3 to 20 percent of white sugar, 1 to 25 percent of fructose, 2 to 5 percent of povidone, and 0.5 to 1.5 percent of sucrose ester, wherein the dedicated Chinese herbal medicinal extract is extracted from dwarf lilyturf tuber, figwort root, fragrant solomonseal, lily, burdock, mint, boat-fruited sterculia seed and reed root. The application of the compound buccal table containing the sodium azulene sulfonate includes treatment of pharyngitis, glossitis, chronic tonsillitis, periodontitis, oral cavity ulcer and other oral cavity diseases, so that discomfortable symptoms caused by oral cavity diseases can be effectively relieved. The sodium azulene sulfonate is compounded with the dedicated Chinese herbal medicinal extract to achieve the aims of quickly treating pharyngitis, glossitis, chronic tonsillitis, periodontitis, oral cavity ulcer and other oral cavity diseases, and various discomfortable symptoms caused by the diseases can be effectively relieved.

The stomatocase treating medicine powder is prepared with 15 kinds of Chinese medicinal materials including safflower leaf, Chinese toon leaf, megranate peel, Chinese toon root bark, cuttlebone, etc. and through selection, rinsing, drying, mixing, crushing, sterilizing, packing and other steps. It is used in treating stomatocase and has the functions of diminishing inflammation, clearing away heat and toxic matter and relieving pain, and thus the fast and obvious treating effect.

The present invention relates to a Chinese medicine for effectively curing ulcerative stomatitis. It is made up by using 8 Chinese medicinal materials of indigo, borax, peppermint, urine sediment, refined mirabilite, cutch, puffball and borneol through a certain preparation process. Said invention also provides the concrete steps of its preparation process.

The invention relates to a biologic active mineral powder chewing gum and a preparation method thereof. The biologic active mineral powder chewing gum comprises the following components in parts by weight: 20-95 parts of gum bases, 3-50 parts of biologic active mineral powder, 0.03-15 parts of carbonate, 0.03-15 parts of phosphate, 0-30 parts of calcium carbonate, 1-30 parts of a sweetening agent, and 1-25 parts of a flavoring agent, wherein the biologic active mineral powder comprises the following substances in percentage by weight: 30-55% of SiO2, 10-35% of CaO, 10-35% of Na2O, 2-10% of P2O5, and 0-15% of K2O. The biologic active mineral powder in the chewing gum disclosed by the invention can inhibit and kill various bacteria in oral cavities, so that oral cavity problems, such as oral infection, dental ulcer and gingivitis, can be prevented and cured, and besides, through the remineralization of the biologic active mineral powder on teeth, the dentin coloboma can be effectively repaired.

The invention relates to capsules or tablets for treating recurrent aphthous ulcer, which is prepared from the following components by weight: 10-20g of fructus ligustri lucidi, 10-20g of eclipta alba, 3-13g of momordica charantia, 7-17g of dendrobium nobile, 15-25g of radix rehmanniae, 0.1-1g of vitamin B2, 1-8g of radix liquiritiae and 10-20g of ophiopogon root. The preparation method comprises the following steps of: cleaning, drying or baking the fructus ligustri lucidi, eclipta alba, momordica charantia, dendrobium nobile, radix rehmanniae, radix liquiritiae and ophiopogon root, crushing, disinfecting at a high temperature, proportioning in parts by weight, adding the vitamin B2 powder, mixing evenly, filling into capsules, and preparing into capsules for treating recurrent aphthous ulcer, or pressing into tablets for treating recurrent aphthous ulcer through a tablet press. In the invention, the source of raw materials is wide, the preparation method is simple, the curative effect is obvious, the recovery rate can achieve more than 90 percent, and the capsules or tablets have no side effect and adverse reaction as well as no drug resistance.

The invention belongs to the field of daily chemical products and specifically relates to children toothpaste containing folium artemisiae argyi polysaccharide and a preparation method thereof. The toothpaste mainly comprises the following components in parts by weight: 1-3 parts of folium artemisiae argyi polysaccharide, 1-2 parts of wolfberry enzyme, 20-30 parts of mouth moistening agent, 1-2 parts of adhesive, 0.2-0.4 part of natural preservative, 20-30 parts of nanometer pearl powder, 5-10 parts of monocalcium phosphate, 2-4 parts of xylitol, 0.3-0.5 part of hydroxymethyl cellulose, 0.5-1 part of sucrose ester-15, 0.5-1 part of monoglyceride, 2-3 parts of vitamin D and 15-25 parts of water. The children toothpaste can effectively solve the oral cavity problems, such as, decayed teeth, angular cheilitis and dental ulcer of children. The toothpaste provided by the invention contains safe ingredients and is suitable for the children under 5 years old.

The invention relates to a Chinese medicament for treating tonsillitis and pharyngitis and process for preparation, wherein the raw material herbs include (by weight ratio) white alum 1-10g, sodium sulfate 30-90g, corpora arenacea 2-8g, borax 3-10g, borneol 2.5-7.5g, musk 0.8-6g, orpiment 2-8g, cow-bezoar 2.5-7.5g, puff-ball 30-50g, depositum urinae hominis 20-80g. The medicament can be prepared into dosage forms of water-paste pill, powders, honeyed bolus, tablets, electuary or capsules.

The invention discloses a preparation method of a pseudo-ginseng extract for toothpaste. In the method, pseudo-ginseng crude medicines are crushed, an aqueous two-phase system formed by a natural eutectic reagent and a salt solution is used as an extraction agent, centrifugation is performed after being processed by microwave-ultrasound with ultrasonic power of 100-400W and microwave power of 100-200W at the temperature of 20-50 DEG C, a bottom phase taken out after centrifugation is the pseudo-ginseng extract for the toothpaste. By using the preparation method provided by the invention, an extract yield can be improved, and meanwhile extraction time can be significantly shortened. In addition, the eutectic reagent which is green, environment-friendly and good in physiological compatibility is used as the extraction agent, so that the condition that the extract does not include organic solvent is ensured, and the extract is reduced in irritation so as to be more accordant with the requirement of environment protection. By adding the pseudo-ginseng extract acquired according to the preparation method provided by the invention into the toothpaste, improvement effect of the toothpaste on symptoms such as dental ulcer, dental plaque, gingivitis and gingival bleeding can be significantly enhanced.

A Chinese medicine in the form of plaster for treating oral mucosa ulcer is composed of a medicinal layer made of the Chinese medicine for treating mucosa ulcer and adhesive and an isolating layer containing water isolating material. Its preparing process is also disclosed.

A product for preventing and healing canker sores may comprise a mouth product; a Dead Sea salt; and sodium chloride mixture. The Dead Sea salt and the sodium chloride mixture may be mixed with the mouth product. The Dead Sea salt and sodium chloride mixture may act to prevent and heal the canker sores.

The invention discloses oral medical ice for preventing and treating dental ulcer and infection after chemotherapy. The oral medical ice includes normal saline; each 100ml of normal saline includes 50-100 micrograms of grain-macrophage colony stimulating factor, 30-100mg of calcium folinate and 250-500mg of lidocaine hydrochloride; and the oral medical ice can be acquired after the normal saline including the above components is frozen to ice. The oral medical ice is used for preventing and treating dental ulcer and infection after high-dose methotrexate chemotherapy or 5-fluorouracil chemotherapy; and the oral medical ice without the calcium folinate can also be used for preventing and treating dental ulcer and infection after other chemotherapies. The oral medical ice disclosed by the invention can be used for alleviating pain, contracting the blood vessels of the oral mucosa, reducing exudation and increasing salivary secretion and can be beneficial to the cleaning of the mouth. The oral medical ice can be slowly molten in the mouth; and the lasting time of the oral medical ice is longer than the time for rinsing the mouth by using collutory. The oral medical ice can be used for improving the chemotherapy tolerance of a patient, promoting the restoration of the oral mucosa ulcer surface, shortening the curing time and reducing the pain of the patient and has no side effects, thereby having good application prospect.

The invention relates to a sticking tablet used for treating human or animal dental ulcer; the oral sticking tablet consists of an adhesive layer containing active components and a water insoluble protective layer; the inactive component containing in the adhesive layer consists of a filling agent, an adhesive sustained-released agent and a lubricant that are applicable to tablet, and the water insoluble protective layer consists of polyacrylic acid resin and / or ethyl cellulose which can be used as protective coatings and a plasticizer, and the active component is momestasone furoate.

A traditional Chinese medicine for treating tympanitis and stomatitis is prepared from 3 Chinese medicinal material materials: bornoel (30-35%), snake slough (20-25%) and alum (40-50%). Its advantages are high curative effect and short course of treatment.

The invention relates to the field of traditional Chinese medicines, and in particular relates to buccal tablets for treating mouth ulcer and a preparation method thereof. The buccal tablets for treating mouth ulcer are prepared from the following traditional Chinese medicine raw materials in parts by weight: 4-6 parts of bezoar, 4-6 parts of borneol, 6-8 parts of liquorice root, 4-6 parts of alunite, 15-20 parts of medicine terminalia fruit, 10-12 parts of medcinal evodia fruit, 6-8 parts of raw arisaema consanguineum schott, 4-6 parts of ginseng, 10-12 parts of Chinese yam, 10-12 parts of bark of Chinese corktree, 6-8 parts of manchurian wildginger, 4-6 parts of honeysuckle flower, 15-20 parts of weeping forsythia capsule, 10-12 parts of wrinkled gianthyssop herb, 10-12 parts of costustoot, 8-10 parts of fortune eupatorium herb, 15-20 parts of Indian buead, 10-12 parts of medicated leaven, 6-8 parts of immature bitter orange, 15-20 parts of root of lobed kudzuvin and 10-12 parts of largehead atractylodes rhizome. The traditional Chinese medicine disclosed by the invention is short in treatment course and quick in action, can be used for astringing and promoting granulation, diminishing inflammation, relieving pain, and repairing mucosa, can be used for treating both symptoms and root causes, hardly causes relapse, also is relatively low in cost, ensures that the immunity of a patient can be enhanced for the whole life after the patient is treated for once; the traditional Chinese medicine disclosed by the invention is convenient to use and is suitable for popularization and application.

The invention relates to an oral reagent, and particularly relates to a reagent for eliminating dental ulcer. The invention provides a reagent for killing oral bacteria and eliminating dental ulcer, wherein the reagent is natural in material, good in effect, convenient to use and low in cost. The technical scheme provided by the invention is as follows: the reagent is prepared from the following raw materials in percentage by weight: 25% of menthol, 20% of xylitol, 10% of green tea powder, 10% of Radix Ophiopogonis, 20% of asparagus fern, 5% of dried radix rehmanniae and 15% of dandelion.

A treatment and prevention formulation for canker sores of the oral cavity including an aqueous alkaline solution having at least three B vitamins, zinc and iron mixed therein and administered to a target area by a spray container. The vitamins are B6, B9 and B12, but may include other vitamins as well. The formulation is all-natural, non-toxic and completely ingestible, so it may be used almost anywhere and at almost any time and can be swallowed after use.

The invention relates to an oral sticking tablet used for treating human or animal dental ulcer; the oral sticking tablet consists of an adhesive layer containing active components and a water insoluble protective layer; the inactive component containing in the adhesive layer consists of a filling agent, an adhesive sustained-released agent and a lubricant that are applicable to tablet, and the water insoluble protective layer consists of polyacrylic acid resin and / or ethyl cellulose which can be used as protective coatings and a plasticizer, and the active component is momestasone furoate.

A Chinese medicine in the form of plaster for treating oral mucosa ulcer is composed of a medicinal layer made of the Chinese medicine for treating mucosa ulcer and adhesive and an isolating layer containing water isolating material. Its preparing process is also disclosed.

The invention belongs to the field of medicines, and relates to a traditional Chinese medicine for treating recurrent oral ulceration and swollen sore throat and use thereof. The invention provides a traditional Chinese medicine composition for treating recurrent oral ulceration and swollen sore throat, for making up the disadvantages in the prior art and relieving pain of patients suffering from recurrent oral ulceration and swollen sore throat. The traditional Chinese medicine provided by the invention is prepared from the following raw materials in parts by weight: 10-12 parts of hawthorns, 5-8 parts of corydalis tuber, 6-9 parts of lotus leaf, 3-5 parts of uncaria, 10-12 parts of mint, 10-12 parts of erigeron breviscapus, 3-5 parts of rhizoma anemarrhenae, 3-5 parts of pinellia ternate, 10-12 parts of ligusticum wallichii, 8-10 parts of mint, 6-9 parts of hairyvein agrimony, 10-12 parts of polygonum cuspidatum, 10-12 parts of folium ginkgo, 10-12 parts of semen cassiae, 12-15 parts of honeysuckle, and 9-12 parts of poria cocos. The traditional Chinese medicine provided by the invention has obvious anti-inflammatory analgesic activities, is obvious in curative effect, safe and reliable, and has a wide clinical application prospect.

The invention relates to a buccal patch, and in particular relates to an edible buccal patch for treating dental ulcer. The edible buccal patch is prepared by the steps of: partially dewatering a bio-cellulose membrane, soaking in a liquid medicine and then drying at low temperature. The edible buccal patch contains Western medicine liquid, traditional Chinese medicine liquid and vegetable juice. The product disclosed by the invention has good paste property, can play good adhesion effect even if various chemical binders are not added, can control slow release of the liquid medicine, and prolongs the action time of the product. The edible buccal patch can be directly eaten, or even has the health-care function. Therefore, the product does not damage a human body even if being used at night long or eaten by a consumer by an error. The edible buccal patch also adopts a combined treatment mode of traditional Chinese medicine and western medicine, and has good treatment effect.

The invention relates to a monomer drug molecule, which can treat toothache and stomatocace, wherein it can treat toothache in 1-5min; and treat stomatocace in 12h, with little consumption as 2-4mg; its formula is [C20H22NO4]+, while its halide will not affect biological activity as [C20H22NO4]-CL.