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Traditional Chinese medicine plaster for treating tunica mucosa oris ulcer and its preparation method

An oral mucosa, traditional Chinese medicine sticker technology, applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, and sheet delivery, etc., can solve problems such as limited application, and achieve the effects of reducing pain, accurate drug dosage, and avoiding migration.

Inactive Publication Date: 2010-08-11
TIANJIN INSTITUTE OF PHARMA RESEARCH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Based on the deficiency of the above dosage forms, the application of the drug in oral mucosal ulcers is limited

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Drug-containing layer:

[0030] Indigo Daisy 10g Catechu 10g Borneol 10g

[0031] Carbopol 934 20g

[0032] 35g powdered sugar

[0033] Microcrystalline Cellulose 10g

[0034] Micronized silica gel 1g

[0035] Magnesium Stearate 1g

[0036] Isolation layer:

[0037] Lactose 12g

[0038] Microcrystalline Cellulose 2g

[0039] Ethylcellulose 4g

[0040] Magnesium stearate 0.2

[0041]Preparation method: the above three flavors and borneol are ground into fine powder; Qingdai and catechu are crushed into fine powder. The above-mentioned powder is compounded with borneol powder and ground, and passed through a 100-mesh sieve. Mix all the drugs, Carbopol 934, powdered sugar, and microcrystalline cellulose, then add micropowder silica gel and magnesium stearate, mix well, and press the drug-containing layer. Separately take lactose, microcrystalline cellulose and ethyl cellulose, mix evenly, moisten with ethanol, pass through a 40-mesh sieve to granulate, add magne...

Embodiment 2

[0043] Drug-containing layer:

[0044] Indigo Daisy 10g Catechu 10g Borneol 10g

[0045] Carbopol 934 40g

[0046] 15g powdered sugar

[0047] Microcrystalline Cellulose 5g

[0048] Copovidone S-630 5g

[0049] Micronized silica gel 1g

[0050] Magnesium Stearate 1g

[0051] Isolation layer:

[0052] Lactose 5

[0053] Copovidone S-630 5g

[0054] Ethylcellulose 8g

[0055] Magnesium stearate 0.2g

[0056] The above three flavors and borneol are ground into fine powder; Qingdai and catechu are crushed into fine powder. The above-mentioned powder is compounded with borneol powder and ground, and passed through a 100-mesh sieve. Mix all the drugs, Carbopol 934, powdered sugar, microcrystalline cellulose, copovidone S-630, etc., then add micropowder silica gel and magnesium stearate, mix well, and form the drug-containing layer for later use. In addition, lactose, microcrystalline cellulose, copovidone S-630, ethyl cellulose, magnesium stearate, etc. were mixed evenly...

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PUM

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Abstract

A Chinese medicine in the form of plaster for treating oral mucosa ulcer is composed of a medicinal layer made of the Chinese medicine for treating mucosa ulcer and adhesive and an isolating layer containing water isolating material. Its preparing process is also disclosed.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and relates to a medicine for treating oral diseases, more specifically, a traditional Chinese medicine patch for treating oral mucosal ulcers and a preparation method thereof. Background technique [0002] Oral ulcers, commonly known as "oral sores", are superficial ulcers that occur on the oral mucosa. In daily life, many people have suffered from "mouth sores". In addition to obvious pain, some of them are accompanied by systemic symptoms, such as low-grade fever and local lymph node enlargement. What we call "oral sores" is a common recurrent oral ulcer, which is a recurrent oral mucosal disease. It is characterized by recurrent, burning pain. Its incidence rate in the population is very high, second only to dental caries and periodontal disease in oral diseases, accounting for the third. [0003] Oral ulcer is common disease, frequently-occurring disease ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/70A61K9/70A61P1/02
Inventor 王亚静李章才
Owner TIANJIN INSTITUTE OF PHARMA RESEARCH
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