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Compound buccal tablet containing sodium azulene sulfonate and application

A technology of sodium azulene sulfonate and buccal tablets, applied to medical preparations containing active ingredients, pharmaceutical formulas, active ingredients of anhydrides/acids/halides, etc., to achieve the effect of relieving discomfort symptoms

Inactive Publication Date: 2011-08-24
天津市顶硕科贸有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Compounded with Chinese herbal medicine to make compound buccal tablets for the treatment of pharyngitis, glossitis, gingivitis, oral ulcers, there is no report

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] 1. First prepare the Chinese herbal medicine extract:

[0017] (1) Take 20-25 kg of Ophiopogon japonicus, 12-16 kg of Radix Scrophulariae, 3-6 kg of Polygonatum Polygonatum, 10-12 kg of Lily, 15-20 kg of Burdock, 2-5 kg ​​of Peppermint, 20-26 kg of Plum Dahai , reed rhizome 30-35 kg, chopped;

[0018] (2) After decocting with 300 kg of deionized water at 100°C (slightly boiling) for 1 hour, filter out the liquid and store it;

[0019] (3) Use 150 kg of deionized water to decoct the dregs of the filtered liquid for 0.5 hour at 100° C. (slightly boiling), and then filter the liquid;

[0020] (4) After mixing the liquids filtered out twice, filter through a 60-mesh sieve, concentrate, and spray-dry to make a special Chinese herbal medicine extract for future use.

[0021] 2. Take 0.2 kg of sodium azulene sulfonate; 89 kg of prepared special Chinese medicine extract; 5.3 kg of white sugar; 3 kg of fructose; 2 kg of povidone; The finished product is obtained by mixing, co...

Embodiment 2

[0023] 1. First prepare the Chinese herbal medicine extract:

[0024] (1) Take 20-25 kg of Ophiopogon japonicus, 12-16 kg of Radix Scrophulariae, 3-6 kg of Polygonatum Polygonatum, 10-12 kg of Lily, 15-20 kg of Burdock, 2-5 kg ​​of Peppermint, 20-26 kg of Plum Dahai , reed rhizome 30-35 kg, chopped;

[0025] (2) After decocting with 300 kg of deionized water at 100°C (slightly boiling) for 1 hour, filter out the liquid and store it;

[0026] (3) Use 150 kg of deionized water to decoct the dregs of the filtered liquid for 0.5 hour at 100° C. (slightly boiling), and then filter the liquid;

[0027] (4) After mixing the liquids filtered out twice, filter through a 60-mesh sieve, concentrate, and spray-dry to make a special Chinese herbal medicine extract for future use.

[0028] 2. Take 0.5 kg of sodium azulene sulfonate; 80 kg of prepared special Chinese medicine extract; 3 kg of white sugar; 11.5 kg of fructose; 4 kg of povidone; The finished product is obtained by mixing, c...

Embodiment 3

[0030] 1. First prepare the Chinese herbal medicine extract:

[0031] (1) Take 20-25 kg of Ophiopogon japonicus, 12-16 kg of Radix Scrophulariae, 3-6 kg of Polygonatum Polygonatum, 10-12 kg of Lily, 15-20 kg of Burdock, 2-5 kg ​​of Peppermint, 20-26 kg of Plum Dahai , reed rhizome 30-35 kg, chopped;

[0032] (2) After decocting with 300 kg of deionized water at 100°C (slightly boiling) for 1 hour, filter out the liquid and store it;

[0033] (3) Use 150 kg of deionized water to decoct the dregs of the filtered liquid for 0.5 hour at 100° C. (slightly boiling), and then filter the liquid;

[0034] (4) After mixing the liquids filtered out twice, filter through a 60-mesh sieve, concentrate, and spray-dry to make a special Chinese herbal medicine extract for future use.

[0035] 2. Take 1 kg of sodium azulene sulfonate; 85 kg of prepared special Chinese medicine extract; 7 kg of white sugar; 2.5 kg of fructose; 3 kg of povidone; 1.5 kg of sucrose lipid. The finished product is...

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Abstract

The invention provides a compound buccal tablet containing sodium azulene sulfonate and an application. The compound buccal tablet containing the sodium azulene sulfonate comprises the following components by weight percent: 0.2 to 1 percent of sodium azulene sulfonate, 80 to 89 percent of dedicated Chinese herbal medicinal extract, 3 to 20 percent of white sugar, 1 to 25 percent of fructose, 2 to 5 percent of povidone, and 0.5 to 1.5 percent of sucrose ester, wherein the dedicated Chinese herbal medicinal extract is extracted from dwarf lilyturf tuber, figwort root, fragrant solomonseal, lily, burdock, mint, boat-fruited sterculia seed and reed root. The application of the compound buccal table containing the sodium azulene sulfonate includes treatment of pharyngitis, glossitis, chronic tonsillitis, periodontitis, oral cavity ulcer and other oral cavity diseases, so that discomfortable symptoms caused by oral cavity diseases can be effectively relieved. The sodium azulene sulfonate is compounded with the dedicated Chinese herbal medicinal extract to achieve the aims of quickly treating pharyngitis, glossitis, chronic tonsillitis, periodontitis, oral cavity ulcer and other oral cavity diseases, and various discomfortable symptoms caused by the diseases can be effectively relieved.

Description

technical field [0001] The invention relates to a compound buccal tablet. In particular, it relates to a compound buccal tablet containing sodium azulene sulfonate, which is compounded with sodium azulene sulfonate and a special traditional Chinese medicine extract, and its use. Background technique [0002] Sodium azulene sulfonate, also known as water-soluble azulene, is an active ingredient of the natural plant chamomile. Its chemical name is 1.4-dimethyl-7-isopropyl-3-azulene sulfonate sodium, and its chemical formula is: C 15 h 17 NaO 3 S 1 / 2H 2 O, dark blue crystal or crystalline powder, odorless and tasteless. [0003] At present, the application of sodium azulene sulfonate researched and developed mainly focuses on the treatment of gastric ulcer. It is compounded with Chinese herbal medicine and made into compound buccal tablet for the treatment of pharyngitis, glossitis, gingivitis, oral ulcer, and there is no report. [0004] The Chinese herbal medicines comp...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K9/20A61P1/02A61P11/04A61K31/185
Inventor 许荧
Owner 天津市顶硕科贸有限公司
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