122 results about "Lithospermum erythrorhizon" patented technology

The invention discloses a poria cocos and flower multiple healing formula as well as a preparation method and application thereof, and relates to the technical field of traditional Chinese medicine preparations. Comprising poria cocos, honeysuckle, scutellaria baicalensis, gallnut, sanguisorba officinalis, lithospermum erythrorhizon and mirabilite. In the formula, the poria cocos has the effects of tonifying spleen, promoting diuresis, calming heart and tranquilizing mind; the honeysuckle flowers have the effects of clearing away heat and toxic materials and dispelling wind and heat; the radix scutellariae has the effects of clearing heat, drying dampness, purging fire and detoxifying; the gallnuts have the effects of clearing lung, reducing fire, clearing damp and healing sore; the radix sanguisorbae has the effects of cooling blood, stopping bleeding, detoxifying and healing sore; in the treatment process of rosacea, the formula can effectively relieve inflammation and improve skin conditions through the effects of clearing away heat and toxic materials, resisting microorganisms, resisting viruses and the like; the problems that in the prior art, the treatment effect on rosacea is unstable, and side effects are large are solved.

The invention relates to plant-based pet ear drops with effects of diminishing inflammation and relieving itching and a preparation method of the plant-based pet ear drops, and belongs to the technical field of veterinary drugs. The invention discloses plant-based pet ear drops. The plant-based pet ear drops are prepared from, by mass, comprising 6%-8% of a tea tree extract, 6%-8% of a witch hazel extract, 6%-8% of a chamomile extract, 6%-8% of a soybean extract, 2%-6% of a lithospermum extract, 2%-6% of a centella asiatica extract, 2%-6% of a mint extract, 2%-6% of a licorice extract, 4%-6% of a humectant, 0.1%-0.5% of a preservative, 0.1%-0.5% of a conditioning agent and the balance of water. Through reasonable matching of various plant extracts, the ear drops have broad-spectrum antibacterial, anti-inflammatory, soothing and repairing effects, and can effectively deal with various common problems of pet ears, such as bacterial infection, fungal infection, allergic dermatitis, ear mite expelling and the like. The pet ear canal cleaner can also be used for cleaning and nursing pet ear canals, is mild in performance, and can effectively remove dirt, dust and wax in the ear canals.

The invention relates to the technical field of separation and purification of radix arnebiae seu lithospermi, in particular to a naphthoquinone compound in radix arnebiae seu lithospermi, a preparation method of the naphthoquinone compound and application of the naphthoquinone compound in preparation of drugs for treating cervical carcinoma, the naphthoquinone compound in radix arnebiae seu lithospermi is chemically named as (Z)-2-ethoxy-5, 8-dihydroxy-3-(4-methyl-1, 3-pentadiene-1-yl) naphthalene-1, 4-diketone, and the structural formula of the naphthoquinone compound is shown in the description. The naphthoquinone compound in the lithospermum is disclosed for the first time, in-vitro anti-tumor pharmacodynamic experiments are carried out on the naphthoquinone compound in the lithospermum, and the experiments show that the naphthoquinone compound in the lithospermum has a certain inhibition effect on human Hela cells; therefore, the naphthoquinone compound in the radix arnebiae seu lithospermi can be applied to preparation of drugs for preventing / treating cervical cancer.

The invention discloses a preparation method and application of lithospermum carbon nanodots with an anti-adrenal cortical carcinoma function, and relates to the field of carbon dots, the lithospermum carbon nanodots are prepared by the following steps: mixing a lithospermum extract and deionized water, and carrying out a hydrothermal reaction to obtain a lithospermum carbon dot aqueous solution; the lithospermum carbon nanodots are used for preparing medicines for resisting adrenal cortex cancer. The lithospermum carbon nanodot provided by the invention has an inhibition effect on proliferation of adrenal cortex cancer cells, especially on the adrenal cortex cancer cells ACHN and 769-P. The lithospermum carbon nanodot disclosed by the invention has a remarkable proliferation inhibition effect on ACC (adrenal cortical carcinoma) cells. The adrenal cortex cancer is a rare and malignant tumor, and traditional treatment methods such as surgery and chemotherapy have certain limitations. Therefore, the development of a new targeted therapy strategy is very important. The lithospermum carbon nanodots can effectively inhibit proliferation of adrenal cortex cancer cells such as ACHN and 769-P through a certain molecular mechanism.

The invention discloses a traditional Chinese medicine composition for breaking diseases, removing food retention and removing stasis, a preparation and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition for breaking diseases, removing food retention and removing stasis is prepared from the following traditional Chinese medicinal materials in parts by weight: 12-18 parts of ardisia japonica, 5-9 parts of rhizoma dioscoreae nipponicae, 8-14 parts of berba aristolochiae mollissimae, 3-7 parts of radix araliae armatae, 7-11 parts of radix tetrastigme, 6-10 parts of herba cistanche and 3-7 parts of lithospermum erythrorhizon. The traditional Chinese medicine compound disclosed by the invention is rigorous in compatibility, takes both symptoms and root causes into consideration, takes effects of breaking diseases, removing food retention, removing blood stasis and dredging collaterals as the core, also takes effects of dispelling wind, eliminating dampness, clearing away heat and toxic materials, tonifying kidney, strengthening bones and supporting healthy energy into consideration, can quickly relieve pain symptoms, can fundamentally improve the core pathogenesis of wind-cold damp evil invasion, qi stagnation, blood stasis and meridian obstruction, and reduces the recurrence rate.

The present invention relates to a topical dermatological composition for improving the skin, comprising exosomes derived from callus of Lithospermum erythrorhizon S., which has excellent properties including cell proliferation promotion, wound healing promotion, anti-inflammation, collagen synthesis promotion, and whitening effects, and may provide a topical dermatological composition for improving the skin having excellent cell inflow characteristics of exosomes, thereby significantly improving the skin physiological activity effects.

The invention discloses a formula of traditional Chinese medicine acne-removing cream and a production process thereof. The traditional Chinese medicine composition is prepared from the following medicinal materials in parts by weight: 5 to 9 parts of radix arnebiae seu lithospermi, 1 to 3 parts of radix angelicae sinensis, 1 to 2 parts of bakuchiol, 20 to 25 parts of linseed oil, 10 to 15 parts of beewax, 1 to 2 parts of rosa rugosa, 1 to 3 parts of radix et rhizoma rhei, 2 to 4 parts of cortex phellodendri, 3 to 5 parts of rhizoma atractylodis-pericarpium citri reticulatae powder, 1 to 2 parts of rhizoma arisaematis powder, 1 to 3 parts of vitamin E, 0.2 to 0.6 part of adenosine, 0.5 to 1 part of Ectoine, 0.1 to 0.3 part of Pinoline and 2 to 4 parts of purified water. Alkannin contained in the radix arnebiae seu lithospermi has strong antibacterial and anti-inflammatory capacities and does not generate the problem of drug resistance, so that the growth of acnes is inhibited from the source. Angelica polysaccharide can promote proliferation of keratinocytes, enhance the skin barrier function and effectively resist external stimulation. Different from common hormones, salicylic acid and other irritant components in traditional acne-removing products, the formula integrates the double effects of safe acne removal and long-acting skin care by means of natural power.

The present invention relates to a topical dermatological composition for improving the skin, comprising exosomes derived from callus of Lithospermum erythrorhizon S., which has excellent properties including cell proliferation promotion, wound healing promotion, anti-inflammation, collagen synthesis promotion, and whitening effects, and may provide a topical dermatological composition for improving the skin having excellent cell inflow characteristics of exosomes, thereby significantly improving the skin physiological activity effects.

This invention belongs to the field of traditional Chinese medicine adhesive bandage technology, specifically relating to a Shengji Yuhong Ointment, its preparation method, and a medicated film adhesive bandage. The Shengji Yuhong Ointment has a hydrogel structure, comprising raw materials, a gel matrix, and nano-zinc oxide or silver sulfadiazine nanoparticles. The raw materials include the following components by weight: 13-17 parts Angelica dahurica, 34-38 parts Glycyrrhiza uralensis, 58-62 parts Angelica sinensis root, 10-14 parts Dragon's Blood, 4-8 parts Lithospermum erythrorhizon, and 0.2-0.25 parts Musk-β-cyclodextrin inclusion complex powder or Musk nanoliposome powder. The matrix comprises the following components by weight: 245-255 parts sesame oil, 57-63 parts beeswax, 93-103 parts polymer material, 37-43 parts plasticizer, 3-8 parts penetration enhancer, and 0.8-1.2 parts preservative. The Shengji Yuhong Ointment of this invention is used in medicated film adhesive bandages, is convenient to use, and is particularly suitable for chronic, difficult-to-heal ulcers and acute wounds requiring accelerated healing.

This invention discloses a Tibetan medicine formula called Mabosongtang Lung-Nourishing Composition and its preparation method and application in modern formulations, more specifically relating to a preparation method and application of Mabosongtang Lung-Nourishing granules, oral liquid, and capsules. The composition is mainly prepared from the following medicinal materials: Tibetan Lithospermum erythrorhizon, Tibetan Rubia cordifolia, Lithospermum erythrorhizon, Bambusa textilis, Morinda officinalis, Lysimachia christinae, Hippophae rhamnoides, and Glycyrrhiza uralensis. The aqueous extract of this composition, with appropriate excipients, is prepared into granules, oral liquid, and capsules using modern pharmaceutical processes. The three formulations are effective, rationally formulated, advanced in dosage form, and stable in quality. They have the effects of calming the lungs, suppressing blood stasis, and clearing lung heat. They can be used for respiratory symptoms caused by the invasion of pathogenic factors into the lungs, and dysfunction of the lung's vital energy and ascending qi, such as cough, wheezing, shortness of breath, etc. (treatment of lung diseases with the above symptoms).

This invention discloses a traditional Chinese medicine composition for treating HPV infection, its preparation, and its uses. The composition comprises the following ingredients in the indicated weight percentages: 10-40 parts of *Hedyotis diffusa*, 10-30 parts of *Smilax glabra*, 10-30 parts of *Hedyotis diffusa*, 10-30 parts of *Paeonia suffruticosa*, 10-40 parts of *Lithospermum erythrorhizon*, 10-30 parts of *Dictamnus dasycarpus*, 10-30 parts of *Radix Paeoniae Rubra*, 10-30 parts of *Cicadae Periostracum*, 10-30 parts of *Astragalus membranaceus*, and 10-30 parts of *Glycyrrhiza uralensis*. It effectively inhibits the replication of human papillomavirus (HPV) nucleic acid, thereby effectively treating cervical HPV infection caused by HPV, as well as infectious skin diseases such as cervical precancerous lesions and condyloma acuminata caused by HPV infection.

The invention provides a traditional Chinese medicine composition for preventing hair loss, growing hair and removing dandruff as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The invention discloses a traditional Chinese medicine composition for preventing hair loss, growing hair and removing dandruff. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 8-12 parts of lithospermum, 8-12 parts of paris polyphylla, 15-25 parts of duckweed, 8-12 parts of golden larch bark, 8-12 parts of lucid ganoderma, 15-25 parts of cocklebur fruit, 15-20 parts of gallnut, 8-12 parts of radix sophorae flavescentis, 5-10 parts of schizonepeta, 8-12 parts of radix saposhnikoviae, 4-8 parts of notopterygium root, 5-10 parts of schisandra chinensis, 5-10 parts of elecampane, 5-10 parts of eclipta, 5-10 parts of ginseng, 5-10 parts of angelica sinensis, 5-10 parts of saponin, 5-10 parts of soapberry and 5-10 parts of broadleaf holly leaf. , 8-12 parts of fructus ligustri lucidi, and 4-8 parts of herb of wiss mannii The invention provides a traditional Chinese medicine composition for preventing alopecia, growing hair and removing dandruff, aiming at improving the problems of alopecia, dandruff and scalp discomfort.

Provided are a traditional Chinese medicine composition for the treatment of psoriasis, a preparation method therefor, and use thereof. In the traditional Chinese medicine composition, indigo naturalis and Lithospermum erythrorhizon compose a basic formula, camellia oil is used as supplement, and coptis chinensis, rhizoma curcumae, or radix sophorae flavescentis are respectively added in different formulas. By means of extracting effective components of indigo naturalis, Lithospermum erythrorhizon, and radix sophorae flavescentis, the traditional Chinese medicine composition can be prepared into a medicament for external use in treating skin diseases and can effectively treat psoriasis.

The external preparation is prepared from the following Chinese herbal medicines in parts by weight: 4 to 20 parts of herba artemisiae scopariae, 2 to 10 parts of cicada slough, 2 to 10 parts of cortex phellodendri, 4 to 20 parts of radix arnebiae seu lithospermi, 2 to 10 parts of radix sophorae flavescentis, 4 to 20 parts of herba agrimoniae, 4 to 20 parts of fructus xanthii, 4 to 20 parts of fructus tribuli, 4 to 20 parts of cortex moutan, 2 to 10 parts of radix rehmanniae, 4 to 20 parts of radix clematidis, 4 to 20 parts of rhizoma dioscoreae, 4 to 20 parts of spina gleditsiae, 4 to 20 parts of herba sedi and 4 to 20 parts of radix saposhnikoviae. The preparation method of the external preparation comprises the following steps: wrapping the weighed raw materials with gauze, soaking in 60-70L of cold water for 2-5 hours, boiling with big fire, decocting with small fire for 4-5 hours, closing the small fire, and taking out soup, thereby obtaining the external preparation. The external preparation developed by the invention has the effects of clearing away heat and toxic materials, promoting diuresis, dispelling wind and arresting itching, and especially has an obvious treatment effect and no toxic or side effect after being assisted by medicated bath.

An analgesic, antipruritic, tissue-regenerating, wound-healing, and antibacterial ointment and its preparation method are disclosed. This invention relates to the field of traditional medicine and skin antibacterial preparations. It comprises the following components by weight: 400-600 parts sesame oil, 30-80 parts beeswax, 25-100 parts a plant-based medicinal composition, 5-25 parts an animal-based medicinal composition, 1-5 parts a mineral-based medicinal composition, and 0.1-0.3 parts an antibacterial agent. The plant-based medicinal composition includes elm branches, willow branches, purple gromwell root, and jujube branches; the animal-based medicinal composition includes dragon's blood and earthworm; the mineral-based medicinal composition is red silver pearl powder; and the antibacterial agent is chlorhexidine acetate. Using pure natural Chinese medicinal herbs as core raw materials, with a reasonable formulation and stable preparation process, it has rapid analgesic, antipruritic, hemostatic, antibacterial, tissue-regenerating, and wound-healing effects. It has significant effects on acute trauma, burns, and chronic, difficult-to-heal wounds, is safe and non-irritating, and has controllable quality.

The invention provides shower balm with itching relieving, bacterium inhibiting and lasting fragrance and a preparation method and application of the shower balm, and belongs to the technical field of balm preparation. The shower head balm comprises the following components in percentage by weight: 1-5% of a thickening agent, 5-10% of a dispersing agent, 15-25% of a plant extract, 5-10% of an emulsifier, 10-20% of an emollient, 0.1-0.3% of a chelating agent, 1-3% of an adhesive, 0.1-0.5% of an antioxidant, 0.3-0.8% of a slow release agent and the balance of water, the plant extract is a mixture of evening primrose oil, cranberry seed oil, a mint leaf extract, a kudzu vine root extract, an angelica sinensis extract and a lithospermum erythrorhizon extract. By reasonably controlling the variety and proportion of the plant extracts, the obtained shower head balm has better effects of inhibiting bacteria, relieving itching, moisturizing, nourishing and lasting fragrance.

The invention belongs to the technical field of medicines, and discloses a gynecological bacteriostatic lotion and a preparation method and application thereof.The lotion is prepared from extracts of traditional Chinese medicinal materials such as radix sophorae flavescentis, cortex phellodendri, coptis chinensis, scutellaria baicalensis, rhizoma smilacis glabrae, cortex dictamni, fructus cnidii, areca nuts, cortex meliae, golden larch bark, lithospermum erythrorhizon, lavender, rheum officinale and honeysuckle as main raw materials, and parachloroxylenol, salicylic acid and borneol as auxiliary materials. A compound preparation with multiple effects is formed through scientific proportioning and a preparation process, the product can effectively inhibit common pathogenic bacteria such as Candida albicans, Staphylococcus aureus and Escherichia coli, shows a broad-spectrum and efficient antibacterial effect, and is small in irritation, high in safety to vaginal mucosa and genital tract environment and free of toxic and side effects. The product can maintain local micro-ecological balance and reduce inflammation recurrence while cleaning and nursing, has the advantages of long-term conditioning of a traditional Chinese medicine compound and rapid sterilization of western medicine components, and is suitable for clinical popularization and application.

The invention provides lithospermum liquid shampoo soap and a preparation method thereof, and belongs to the technical field of liquid soap. The preparation method comprises the following steps: mixing lithospermum oil, nigella nigra seed oil and coconut oil to obtain a vegetable oil mixture I; mixing more than two of fennelflower essential oil, lavender essential oil, jasmine essential oil and ginger essential oil to obtain a vegetable oil mixture II; freezing the Wumann grass juice, and adding potassium hydroxide for dissolving to obtain alkali juice; adding the alkali juice into the first part of the vegetable oil mixture I, stirring for emulsification reaction, then adding the vegetable oil mixture II, and continuously stirring to obtain liquid soap; putting the liquid soap into a mold, and carrying out saponification reaction to obtain a soap blank; mixing the soap embryo with lavender hydrolat, heating until the soap embryo and the lavender hydrolat are completely dissolved, then adding a second part of the vegetable oil mixture I and the emulsifier, and carrying out secondary emulsification; and adding a selective functional additive, uniformly mixing, standing and filtering. The liquid shampoo soap is mild, high in active matter content and excellent in heat-resistant and cold-resistant stability.

This invention provides a traditional Chinese medicine composition for reflux esophagitis, relating to the field of traditional Chinese medicine pharmaceutical technology. The composition comprises rose, Lithospermum erythrorhizon, Sargentodoxa cuneata, Rabdosia rubescens, honeysuckle, licorice, Evodia rutaecarpa, pearl, Coix seed, and Salvia miltiorrhiza. This composition is obtained through rational combination based on the principles of traditional Chinese medicine syndrome differentiation and treatment, with synergistic effects among the various herbs. This invention's composition exhibits significant anti-inflammatory effects and demonstrates significant repair and improvement effects on damaged esophageal mucosa. It shows significant efficacy in treating reflux esophagitis, significantly improving the treatment effectiveness and cure rate, significantly alleviating patient discomfort and pain. This invention's composition is a pure traditional Chinese medicine preparation, with no toxic side effects and no drug resistance.

The application discloses a construction method of a UPLC characteristic spectrum of a radix-lithospermi and application thereof, 1) preparation of a control medicinal material reference solution; 2) preparation of a control reference solution: a certain amount of protocatechuic acid, protocatechuic aldehyde, ferulic acid, rosmarinic acid, caffeic acid tetramer and danshensu are taken to prepare a mixed solution by adding methanol, serving as the control reference solution; 3) preparation of a test solution; 4) determination: the control medicinal material reference solution, the control reference solution and the test solution are respectively taken and injected into a liquid chromatograph to determine characteristic spectra, wherein the characteristic spectra include at least 12 characteristic peaks; 5) qualitative analysis of a sample to be determined is carried out by using the characteristic spectra obtained in the above steps. The characteristic spectrum includes 12 characteristic peaks, can effectively distinguish radix-lithospermi (Xinjiang radix-lithospermi) and its pseudo products of different origins, and embodies the integrity of quality control of radix-lithospermi.

This application belongs to the field of traditional Chinese medicine, specifically relating to a spleen-strengthening and blood-activating traditional Chinese medicine preparation that enhances the expression of metallothionein and its uses. This application provides a traditional Chinese medicine composition comprising, by weight, the following raw materials: 1-20 parts jujube, 1-20 parts yam, 1-10 parts Buddha's hand, 1-9 parts Lithospermum erythrorhizon, 1-9 parts corn silk, 1-9 parts lotus leaf, 1-15 parts ginseng leaf, and 1-20 parts hawthorn. This application also provides a traditional Chinese medicine preparation, as well as the uses of the above-mentioned traditional Chinese medicine composition and preparation. The traditional Chinese medicine preparation provided in this application effectively enhances the liver's detoxification, antioxidant, and anti-inflammatory capabilities by increasing the expression of hepatic metallothionein, thereby reducing the probability of liver damage and preventing and delaying the further development of liver diseases.

This invention belongs to the field of medical pharmaceuticals, specifically relating to a traditional Chinese medicine alcohol dressing and its application method; a traditional Chinese medicine alcohol dressing comprising one of Lithospermum erythrorhizon, borneol, or Polygonum cuspidatum, and alcohol; the weight ratio of one of Lithospermum erythrorhizon, borneol, or Polygonum cuspidatum to alcohol is 1.5–2:10; a method of applying the traditional Chinese medicine alcohol dressing includes the following steps: clearing static electricity; spraying the traditional Chinese medicine and alcohol onto the wound and blisters, avoiding the mouth, eyes, ears, and nose, for rapid pain relief and heat dissipation; preserving the intact wound and blisters; implementing corresponding treatment measures according to the type of burn; discharge from the hospital after treatment and rest at home to allow the biological cells' electromagnetic sensing self-healing ability to recover; during the operation of the aforementioned method, to avoid secondary trauma, the burn wound must never be bandaged or disinfected with iodine; only spraying and application are permitted. This application invents a traditional Chinese medicine alcohol dressing and its application method, which is highly targeted, effectively relieves pain and prevents infection, reduces scar formation, and is suitable for different types of burns.

The invention discloses scald ointment with a superstrong healing function, and relates to the field of scald ointment. According to the scald ointment with the super-strong healing function, the honey can keep a wound moist, reduce pain and prevent infection; the garden burnet has the effects of astringing to stop bleeding, diminishing inflammation and detoxifying, and can relieve edema, relieve pain and promote granulation tissue growth when being used for scalds; the radix arnebiae seu lithospermi has the effects of clearing away heat and toxic materials and cooling and activating blood and can promote cell regeneration, diminish inflammation and repair damaged skin; the coptis chinensis has relatively strong antibacterial and anti-inflammatory effects and is suitable for preventing and controlling scald infection; scutellaria baicalensis has the effects of clearing heat, drying dampness, purging fire and removing toxin, and is cooperated with coptis chinensis to enhance the antibacterial and anti-inflammatory effects and relieve the heat toxin symptom caused by scald; borneolum syntheticum has the effects of cooling, relieving pain and diminishing inflammation, can immediately relieve pain and burning heat caused by scald, and promotes transdermal absorption of the medicine; all the components interact to remarkably improve the healing speed of the wound surface, and the formula adopts natural components and is small in side effect and rapid in comprehensive effect.

The invention discloses a process for treating burns and scalds without using antibiotics. The process comprises the following steps: S1, setting a treatment environment: carrying out the whole burn and scald treatment process in a sterile room; s2, heat-dissipating and pain-relieving operation: spraying an antibacterial, pain-relieving and heat-dissipating spray on the wound surfaces of the burns and scalds every 5-10 minutes; s3, wound surface treatment measures: preparing special medicine patch gauze for wound surface treatment; 30% of alcohol lithospermum liquid, 15% of pseudo-ginseng liquid and a proper amount of alcohol are blended into a 75-degree alcoholic solution, gauze is soaked to prepare the medicine patch, the medicine patch is directly applied to burn and scald wounds, the wounds are kept in an unbound state, it is ensured that the wounds make full contact with air, heat dissipation and drying are facilitated, and the bacterium breeding environment is reduced. The problem of bacterial drug resistance and adverse drug reaction caused by use of antibiotics are effectively avoided, the body burden of patients is relieved, and the traditional Chinese medicine composition is beneficial to long-term health of the patients.

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine nano preparation for treating gynecological infection and a preparation method thereof. The traditional Chinese medicine nano preparation comprises the following raw materials in parts by weight: 30-60 parts of traditional Chinese medicine extract, 20-40 parts of PLGA, 15-30 parts of mucous membrane penetrating peptide modified chitosan, 30-60 parts of carboxymethyl chitosan, 20-40 parts of oxidized sodium alginate and 5-15 parts of polyvinyl alcohol, the traditional Chinese medicine extract of coptis chinensis, lithospermum erythrorhizon, radix sophorae flavescentis, astragalus membranaceus and liquorice is taken as a core, core-shell nanoparticles are formed through PLGA, and the core-shell nanoparticles are prepared into the traditional Chinese medicine nano preparation. According to the preparation method, mucous membrane penetrating peptide modified chitosan is adopted for coating, finally, the mucous membrane penetrating peptide modified chitosan is loaded in pH intelligent response type hydrogel composed of carboxymethyl chitosan and oxidized sodium alginate, the constructed important nano preparation has the synergistic effects of efficient mucous membrane penetrating, targeted accumulation and antibacterial-anti-inflammatory-repair, and the bioavailability and the treatment safety are remarkably improved.

The invention discloses a plant extract-containing composition applied to eczema and application of the plant extract-containing composition, and belongs to the technical field of cosmetics. The composition is prepared from the following components in parts by mass: 2 to 20 parts of folium mori extract, 2 to 20 parts of aloe barbadensis leaf polysaccharide, 2 to 20 parts of colloidal oat powder, 0.5 to 12 parts of bisabolol, 2 to 20 parts of ceramide, 15 to 40 parts of herba portulacae extract, 15 to 40 parts of radix gentianae extract and 15 to 40 parts of radix arnebiae seu lithospermi extract. The composition provided by the invention breaks through the limitation of a traditional single target spot, realizes four-dimensional regulation and control of inflammation control, targeted soothing, micro-ecological regulation and barrier reconstruction, and has a better treatment effect on eczema.

The invention provides a compound lithospermum erythrorhizon seaweed gel preparation capable of improving skin problems, the preparation comprises a carrier and an active component connected with the carrier, the carrier is a sodium alginate gel matrix, the active component comprises a modified lithospermum erythrorhizon ointment mixture, the modified lithospermum erythrorhizon ointment mixture exists in a microcapsule form, and the microcapsule is a microcapsule. Wrapping the modified lithospermum ointment mixture serving as a water phase in an oil phase in the microcapsule; the modified radix arnebiae seu lithospermi ointment mixture is prepared from the following raw materials: radix arnebiae seu lithospermi, radix angelicae sinensis, radix angelicae, frankincense, myrrh, green tea, raw rhizoma typhonii, silkworm larva, radix astragali seu hedysari, flos lonicerae, flos chrysanthemi, rhizoma anemarrhenae and calcined gypsum. According to the invention, through a microcapsule packaging technology of the modified lithospermum ointment mixture with a specific ratio and in combination with a sodium alginate gel carrier, the stability and bioavailability of the active ingredients are remarkably improved, the slow release and long-acting effects of the active ingredients are realized, and meanwhile, the oil phase combination and preparation process are optimized; the skin problem is effectively improved on the premise of ensuring the mildness.

The invention provides a traditional Chinese medicine composition for treating psoriasis as well as a preparation method and application thereof, the traditional Chinese medicine composition takes indigo naturalis and lithospermum as a basic formula, camellia oil is supplemented, and Sichuan coptis root, radix sophorae flavescentis and rhizoma zedoariae or different combinations thereof are respectively added in different compatibility; according to the invention, the ground powder and / or the extracted active ingredients are combined according to the mass parts; according to the invention, active ingredients of indigo naturalis, lithospermum erythrorhizon and sophora flavescens are extracted, and compatibility is carried out based on the obtained active ingredients to obtain different ointments and pharmaceutically achievable medicament forms for treating psoriasis. The compound preparation comprises traditional Chinese medicine components and skin protection components for combined use, and the treatment effect is more comprehensive through the combined action of exterior and interior. And the traditional Chinese medicine composition is prepared from all natural components, so that the side effects are low, and hormone dependence is avoided.

The invention relates to pan dragon jade and lithospermum gel as well as a preparation method and application thereof. The pan dragon jade and lithospermum gel is prepared from the following components in parts by weight: 20 to 50 parts of lithospermum oil mixed oil phase, 1 to 25 parts of pan dragon jade powder, 10 to 40 parts of surfactant, 2 to 8 parts of gel matrix, 200 to 700 parts of water phase, 25 to 75 parts of humectant, 1 to 5 parts of pH regulator and 0.5 to 2 parts of preservative, the lithospermum oil mixed oil phase is composed of lithospermum oil and a first oil phase, the mass ratio of the lithospermum oil to the first oil phase is 1: (0-10), and the lithospermum oil is prepared by wetting segment-shaped or granular lithospermum with a second oil phase, dipping and percolating. The oil-phase percolate is directly adopted as a target medicine to prepare the medicine-carrying oil phase, pan dragon jade powder is adopted as a mineral medicine, the advantages of the oil-phase percolate and the pan dragon jade powder are combined, and the gel which is good in stability, moderate in viscosity and easy to coat is obtained.

The invention discloses a dehumidifying and detoxifying medicine for treating eczema and a preparation method thereof. The medicine is prepared from radix sophorae flavescentis, herba portulacae, cortex phellodendri, fructus cnidii, radix sanguisorbae, cortex dictamni, radix salviae miltiorrhizae, nidus vespae and Sinkiang lithospermum erythrorhizon. The traditional Chinese medicine has the effects of clearing heat, drying dampness, astringing liquid, cooling blood, removing toxicity, diminishing swelling, dispelling wind, arresting itching and astringing sores, can be used for treating symptoms such as skin redness and swelling, scorching hot, papule, blister, erosion and exudation caused by eczema, and is suitable for patients with eczema caused by damp-heat accumulation in skin and exuberance of blood heat and toxin.