11 results about "VALERIAN EXTRACT" patented technology

The present invention aims to provide a method for evaluating the serotonin reuptake inhibitory effect of a composition containing valerian extract. [Solution] The present invention provides a method for evaluating antidepressant effects, which involves quantitatively analyzing one or more components contained in at least a part of a plant of the genus Valerian or a processed product thereof, and evaluating the antidepressant effect of the test substance by referring to the results of the quantitative analysis and criteria for antidepressant effect.

The invention belongs to the field of traditional Chinese medicines, and provides application of a valerian extract in preparation of a medicine for preventing and treating climacteric syndrome. Pharmacological experiments show that the valerian extract has a regulation effect on a hypothalamic-pituitary-neuroendocrine system, and has important significance in regulating postmenopausal endocrine conditions of middle-aged and old women and improving anxiety, insomnia, dysphoria and other climacteric symptoms related to FSH (follicle stimulating hormone) and LH (luteinizing hormone). In addition, the valerian extract has a good regulation effect on secretion of related sex hormones and hypothalamus neurotransmitters of climacteric rats, and has a certain correction effect on the central monoamine neurotransmitter disorder state of the climacteric rats. The traditional Chinese medicine composition can improve clinical symptoms of climacteric syndrome.

A meat core is formed by baking young pigeon meat and chicken, functional components such as deep sea fish oil, linseed oil and the like are embedded in a wall material containing cranberry powder, chicory roots, lactoferrin and zinc to form a functional coating to wrap the meat core, and a vacuum freeze drying technology is combined, so that the activity of the functional components is effectively protected, and the release performance is improved; zinc ions are supplemented, so that the antibacterial property and the stability are enhanced, and the hair health is promoted. The outermost layer of the cat food adopts the chicken liver powder, the valerian extract and chitosan to form a barrier oil film, oxidation is remarkably delayed, the shelf life is prolonged, meanwhile, the chicken liver powder and the valerian extract are used for improving the food calling effect and the emotion relieving effect, and the palatability is further improved. Unification of functional activity protection, texture optimization and product stability is realized.

The present application belongs to the field of natural medicine, and provides a valerian self-microemulsion drop pill and a preparation method thereof, which is prepared from the following components by weight: valerian volatile oil 20-40 parts, valerian extract powder 8-10 parts, oil phase 10-30 parts, emulsifier 40-80 parts, co-emulsifier 10-50 parts, and base 200-650 parts. The volatile oil and alcohol-soluble components of valerian are extracted, and are prepared into self-microemulsion together with oil ester, emulsifier and co-emulsifier, so as to increase the drug solubility, promote the absorption of the drug, and improve the bioavailability. Then, the self-microemulsion is solidified in the form of drop pill, so as to obtain the valerian self-microemulsion drop pill with high drug solubility, high bioavailability and good stability. By controlling the mass ratio of the base and the valerian self-microemulsion, the heating temperature of the drug-containing base, and the drop distance, the forming rate of the drop pill can reach more than 90%.

The invention provides a valerian extract, a preparation method and application of the valerian extract in sleep-aiding products, and belongs to the technical field of plant extracts and sleep-aiding products. The valerian extract is prepared by performing pretreatment, low-temperature enzymolysis, segmented extraction and ultrafiltration purification on valerian rhizomes. The prepared valerian extract is applied to a water-based sniffing type sleep-aiding product, and the water-based sniffing type sleep-aiding product is obtained by taking the valerian extract as a core active component and compounding the valerian extract with other sleep-aiding components. According to the preparation method disclosed by the invention, the retention rate and the purity of valerian are remarkably improved, and the obtained water-based sniffing type sleep-aiding product does not need to be smeared or pressed and can play a role only through natural sniffing. The preparation process has the advantages of clear parameters, easily available raw materials and conventional equipment, can be directly applied to industrial production, and has the advantages of good product stability, long shelf life and wide market application prospect.

The invention provides valerian and application of a valerian preparation in preparation of a medicine for treating chronic cholecystitis. The valerian is an oral preparation prepared from a valerian medicinal material or a valerian extract as an active ingredient according to a conventional preparation method. The oral preparation is an electuary, a granule, a micro-capsule, a soft capsule, a tablet or an oral liquid. The valerian has the effects of soothing liver-qi stagnation, promoting blood circulation to remove blood stasis, promoting qi circulation to relieve pain and removing toxicity for detumescence, pharmacological experiments show that the valerian and the preparation thereof have the effects of improving immunity and resisting infection of pathogenic microorganisms and can accelerate excretion of gall bladder bile of mice, and the effects may be the pharmacological basis of the effects of soothing liver-qi stagnation, regulating qi and relieving pain; the effective rates of the traditional Chinese medicine for treating qi stagnation and blood stasis type chronic cholecystitis and liver and gall qi stagnation type chronic cholecystitis are 96.0% and 92.8% respectively, the curative effect is remarkable, and the cure rate is high. The traditional Chinese medicine composition is good in clinical curative effect, high in safety and few in adverse reaction, and a new method is provided for clinical treatment of chronic cholecystitis.

The application discloses an anti-aging composition containing recombinant collagen and a preparation method thereof and belongs to the technical field of anti-aging compositions. The preparation method comprises the following steps: preparing material A by taking salvia, uva-ursi leaves, pineapple pulp, salvia miltiorrhiza, caesalpinia and deionized water as raw materials; mixing deionized water and 1,3-butanediol, adding recombinant human type III collagen powder and scallop extract to obtain material B; mixing borneol extract, valerian extract, alocasia macrorrhiza extract, yizhi extract, isopropyl myristate, Tween-20, polyethylene glycol-400, material A and material B, and performing shear homogenization treatment to obtain material C; mixing deionized water and carbomer powder, adding carboxymethyl chitosan powder, adjusting the pH to neutral, adding material C and performing ultrasonic mixing to obtain the anti-aging composition; and the synergistic effect among the components is used to improve the anti-aging effect.

The invention discloses a herbaceous plant extract compound for regulating emotion of pets, a preparation method of the herbaceous plant extract compound and application of the herbaceous plant extract compound in pet food. The compound comprises the following components in percentage by dry weight: 15-35% of valerian extract, 10-28% of passion flower extract, 5-20% of radix bupleuri extract, 3-15% of melissa officinalis extract, 3-12% of chamomile extract, 20-50% of beta-glucan carrier and the balance of nutrition enhancer and functional auxiliary materials. Plant active ingredients are extracted by adopting a supercritical CO2 extraction technology, stability and bioavailability are improved through beta-glucan embedding, and multi-target collaborative regulation is realized. The product disclosed by the invention is natural and safe, can obviously improve the separation anxiety, aggressive behavior and fear reaction of pets, has the anxiety behavior improvement rate of 67%, aggressive behavior reduction of 54% and fear reaction relief of 72%, has no side effect, is suitable for long-term use, and can be widely applied to staple food grains, snacks and nutritional supplements for pets.

The present application relates to the technical field of medicine, and provides a valerian microemulsion temperature-sensitive gel, a preparation method and application thereof.The valerian microemulsion temperature-sensitive gel is composed of a drug valerian extract, an oil phase, a surfactant, a cosurfactant, poloxamer, carboxymethyl chitosan and water.The prepared valerian microemulsion temperature-sensitive gel is in a liquid state at normal temperature, and is converted from the liquid state to a gel state when contacting the skin or mucosa temperature, has almost no irritation to the skin, is safe to use, has a large transdermal permeation amount, a high transdermal permeation rate, a long retention time on the skin surface or mucosa, and has a good sustained-release effect.The preparation method is simple, low in cost, convenient and safe to use, and can effectively promote skin wound healing.The present application provides a new drug dosage form for treating skin wounds or mucosa administration.

Composition including: a) Melatonin up to 5 mg; b) Magnesium up to 500 mg c) Withania somnifera up to 2 g; d) Gamma-aminobutyric acid up to 500 mg; e) L-tryptophan up to 1 g; f) L-Theanine up to 50 mg; g) 5-Hydroxytryptophan up to 100 mg; h) Matricaria chamomilla extract up to 500 mg; i) Valeriana officinalis extract up to 800 mg; and j) Vitamin B6 up to 5 mg.

The invention provides a double-effect slow-release liquid preparation for stress protection and immunity enhancement of pets and a preparation method of the double-effect slow-release liquid preparation, and belongs to the technical field of pet nutrition and health care. The skin care product comprises the following raw materials: 2-4 parts of a valerian extract, 1-2 parts of gamma-aminobutyric acid, 3-6 parts of yeast beta-glucan, 2-4 parts of lactoferrin, 1-2 parts of vitamin E, 0.5-1 part of a rosemary extract, 5-8 parts of olive oil, 3-5 parts of Tween 80, 2-3 parts of chicken protein hydrolysate and 50-60 parts of deionized water. The preparation method comprises the following three core steps: preparing an oil phase, preparing a water phase, dropwise adding the oil phase into the water phase, carrying out high-speed shearing to form a microemulsion, and coating the microemulsion with a temperature-sensitive chitosan solution. Through combination of specific component compounding and a microemulsion-chitosan slow release technology, synergy of rapid stress relief and long-acting immunity enhancement is realized for the first time, meanwhile, the stability and palatability of the product are remarkably improved, and the technical problems that an existing product is single in function and pet food refusal is caused are solved.