The invention provides a
meloxicam patch as well as a preparation method and application thereof. The
meloxicam patch comprises a back lining layer, a
medicine storage layer and an anti-sticking layer, wherein
medicine storage layer is prepared from an
active component-
meloxicam or pharmaceutically acceptable salts thereof, pressure-sensitive
adhesive and a
drug transdermal absorption accelerant, wherein the dosages of the meloxicam or the pharmaceutically acceptable salts thereof and the
drug transdermal absorption accelerant respectively account for 0.5-60% and 0.1-50% of the
solid component weight content of the
medicine storage layer. The preparation method of the meloxicam patch comprises the steps of dissolving the meloxicam or the pharmaceutically acceptable salts thereof into a
solvent, sequentially adding all pharmaceutic accessories into the obtained solution, stirring and evenly mixing; standing and degassing,
coating, volatilizing the
solvent, compounding the back lining layer, and
cutting the product into a patch with suitable size according to the dosage requirement. The meloxicam patch is high in adhesiveness and good in flexibility, not only can avoid stimulation, caused by orally taking a medicine, for the
gastrointestinal tract, but also can improve the
transdermal permeation of the medicine, is lasting and stable in
curative effect, and can be interrupted at any time.