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Skin care composition capable of dispelling wrinkles and resisting ageing, and purpose of skin care composition capable of dispelling wrinkles and resisting ageing

A skin care composition and anti-aging technology, which can be applied to skin care preparations, cosmetic preparations, medical preparations containing active ingredients, etc. The effect of improving skin elasticity and improving skin condition

Pending Publication Date: 2020-05-12
张传旋
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are various types of products on the market, such as moisturizing water, sunscreen, etc. Most of them add exogenous active substances, such as sunscreens, free radical scavengers, moisturizers, etc., to partially delay skin aging, but most Single effect, unsatisfactory effect

Method used

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  • Skin care composition capable of dispelling wrinkles and resisting ageing, and purpose of skin care composition capable of dispelling wrinkles and resisting ageing
  • Skin care composition capable of dispelling wrinkles and resisting ageing, and purpose of skin care composition capable of dispelling wrinkles and resisting ageing
  • Skin care composition capable of dispelling wrinkles and resisting ageing, and purpose of skin care composition capable of dispelling wrinkles and resisting ageing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] An anti-wrinkle and anti-aging skin care composition, comprising: 0.5 parts of recombinant human epidermal growth factor, 10 parts of low-molecular-weight hyaluronic acid dispersion, 2 parts of high-molecular-weight hyaluronic acid, effective doses of acetyl hexapeptide-3 and acetyl 1 part of base hexapeptide-8 composition, 1.5 parts of lipid nanocapsules containing astaxanthin and lycopene.

[0057] The preparation method of the above-mentioned wrinkle-removing and anti-aging skin care composition comprises the following steps:

[0058] (1) Using a high molecular weight hyaluronic acid solution with an initial concentration of 2 g / L as raw material, it was degraded for 6 hours in an ultrasonic environment with a frequency of 60 kHz, a temperature of 25 ° C, and a pH value of 7.5 to obtain a molecular weight of 17 × 10 4 low molecular weight hyaluronic acid;

[0059] (2) Add alginate and β-glucan to sterile water containing propylene glycol, stir at 75°C to form a unif...

Embodiment 2

[0066] An anti-wrinkle and anti-aging skin care composition, comprising: 1.5 parts of recombinant human epidermal growth factor, 8 parts of dispersion of low molecular weight hyaluronic acid, 1.5 parts of high molecular weight hyaluronic acid, effective amount of acetyl hexapeptide-3 and acetyl 1.5 parts of base hexapeptide-8 composition, 0.3 parts of carnosine, 0.2 parts of palmitoyl tetrapeptide-7, and 3.5 parts of lipid nanocapsules containing astaxanthin and lycopene.

[0067] The preparation method of the above-mentioned wrinkle-removing and anti-aging skin care composition differs from the steps in Example 1 in that:

[0068] Step (1) Using high molecular weight hyaluronic acid solution with an initial concentration of 2.5g / L as raw material, ultrasonically degrade it for 4.5h to obtain a molecular weight of 23×10 4 low molecular weight hyaluronic acid;

[0069] Step (3) Take low-molecular-weight hyaluronic acid and hydrogel in a weight ratio of 0.5:2.5, and then add 0....

Embodiment 3

[0073] An anti-wrinkle and anti-aging skin care composition, wherein the raw materials and parts by weight are consistent with those in Example 1.

[0074] The preparation method of the above-mentioned wrinkle-removing and anti-aging skin care composition optimizes the steps in Example 3, and the specific optimization measures are as follows:

[0075] Step (6) mixes glycerol and water by weight ratio 3:1, and adds 0.15wt% accelerator, forms water phase, makes lipid nanocapsule, and above-mentioned accelerator is that weight ratio is 1:0.8 berberine hydrochloride and talcoside, the average particle size of the obtained lipid nanocapsules is 79.3nm, the polydispersity index is 0.105, and the Zeta potential is -34.1mV;

[0076] Other steps were consistent with Example 1 to prepare wrinkle-removing and anti-aging skin care composition.

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Abstract

The invention provides a skin care composition capable of dispelling wrinkles and resisting ageing, and a purpose of the skin care composition capable of dispelling wrinkles and resisting ageing, andbelongs to the technical field of cosmetics. The composition comprises growth factors comprising recombinant human crust growth factors, hydrating agents comprising low molecular weight hyaluronic acid which exists in protective colloid and exists in the form of dispersoid, an active peptide composition comprising acetyl hexapeptide-3 and acetyl hexapeptide-8, and an antioxidant which exists in the form of lipid nanocapsules and comprises astaxanthin and lycopene. The composition provided by the invention can arouse cell activity, delay running off of protein, promote increase of protein content, repair skin injury, retain water, replenish water, reduce the dissipating quantity of skin moisture, controlling water-oil balance, increase skin elasticity and alleviate skin photoaging, is highin transdermal absorption efficiency and absorption rate, high in retention volume and effective utilization rate and good in storage stability, and can restrain the activity of matrix metalloproteinase-1; and the composition can be used for cosmetics, wound surface rehabilitation materials or / and scar reduction materials.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to a wrinkle-removing and anti-aging skin care composition and its application. Background technique [0002] The skin is a natural barrier between the external environment and the body, protecting the organs in the body from the effects of temperature and humidity changes, as well as the external environment, such as ultraviolet rays and pollutants, etc. Human skin consists of epidermis, dermis and subcutaneous tissue constitute. However, the protective effect of the skin is limited. When the external influence exceeds a certain level, its function will be weakened due to various factors such as genetics, environment, and social psychology, and it will show symptoms of aging. Skin aging is a gradual physiological process. The skin barrier function is gradually damaged, resulting in water loss, making the skin dry, and increasing the skin's susceptibility to external ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/64A61K8/73A61K8/35A61K8/31A61K8/34A61K8/40A61K8/14A61K8/02A61Q19/08A61Q19/00
CPCA61K8/025A61K8/14A61K8/31A61K8/347A61K8/35A61K8/40A61K8/64A61K8/733A61K8/735A61K2800/522A61K2800/592A61K2800/5922A61K2800/782A61Q19/00A61Q19/08
Inventor 张传旋
Owner 张传旋
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