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Preparation method and application of ginsenoside-loaded triple-assembled pickering emulsion

PendingCN122251245Agood physical and chemical stabilitysignificant improvement <other></other>Cosmetic preparationsHydrocarbon active ingredientsBULK ACTIVE INGREDIENTPhenol
The application relates to a preparation method and application of a ginsenoside-loaded triple-assembled Pickering emulsion, and belongs to the biomedical technology field. In order to solve the problems that the Pickering emulsion constructed by natural active ingredients in the prior art has insufficient mechanical strength of an interface film, is easy to break and lose stability, has passive release behavior, lacks controllability and environmental responsiveness, and is difficult to realize precise release, a ginsenoside-loaded triple-assembled Pickering emulsion is provided. Through a three-step cascade strategy of "molecule-interface-function", a stable "metal-phenol coordination network" interface layer is constructed on the surface of oil droplets, the physical and chemical stability of the emulsion is fundamentally improved, a Pickering emulsion which is all-natural, highly stable and has a pH response intelligent release function is successfully constructed, and the triple-assembled Pickering emulsion has significant advantages in stability, controllable release and function integration, and provides a feasible technical strategy for a response type delivery system design based on natural products.
Owner:CHANGCHUN UNIV OF CHINESE MEDICINE +1