657results about How to "Fast penetration" patented technology

Systems that can include a microneedle array and a small molecule metabolic reporter are disclosed. The systems can be used to penetrate the epidermis and monitor the change in concentration of one or more metabolite or analyte.

An earth wellbore heat loop system has been developed which has, in certain aspects, a heat loop wellbore in the earth extending from an earth surface down into the earth to a bottom of the wellbore, a heat loop disposed in the heat loop wellbore and extending down to a position near the bottom thereof, the heat loop including a heat loop comprising pipe and a bottom member, the pipe extending down to the bottom member on one side thereof and up from the bottom member on another side thereof, the bottom member comprising a body, a first bore through the body extending from a first opening of the body to a second opening of the body, the first opening and the second opening each sized and configured for receipt therein of an end of a heat loop pipe, a second bore having at least a one opening on the body, the second bore sized and configured for securement thereat of an end of coil tubing. Filler material has been developed for use in a heat loop wellbore that has, in certain aspects an amount of water, and an amount of a gel material, such as a polymer. An amount of thermally conductive solids may be used with the polymer and the water.

An earth energy loop transfer system with a moving energy transfer fluid, the system for transferring energy for an entity, the system having means for measuring an amount of energy transferred for the entity to or from the moving energy transfer fluid, and means for invoicing the entity for the amount of energy transferred. The system including means for calculating a price for the amount of energy transferred, said invoicing based on said price. The system including means for transmitting a signal indicative of a measured amount of energy transferred from the means for measuring to the means for invoicing. Methods are disclosed for using such systems to measure and calculate an amount of energy transferred and / or to invoice an entity for the transferred energy.

Apparatus and methods for rapid tissue crossing are described utilizing a device to penetrate and rapidly cross a tissue layer in a patient body without the need to withdraw the tissue visualization catheter out of the patient body to be replaced with a separate dilator. The distal end of a dilator sheath, within which the visualization device is positionable, may be collapsible to form a conical dilator. Upon the placement of the tip of the dilator at the site of transseptal puncture, the conical dilator may be advanced distally through the puncture to enlarge the opening. With passage of the dilator sheath through the opening, a visualization hood may be advanced and deployed through the conical dilator which opens from its conical shape to allow the passage of the hood or other instruments therethrough.

The present invention relates to a disposable injection device for delivering a dose of medicament, comprising a generally elongated housing (10), a container (14) containing medicament to be injected through a needle (16), force means (34) acting on said container and capable of, upon activation, move said container and said needle for penetration and subsequently expelling medicament through said needle, activating means (26) arranged to activate said force means, characterized in that said activating means comprises a needle shield (12) arranged slidable in relation to said housing, a collapsible holding member (58) connected to the inner end of said needle shield, whereby, upon movement of said needle shield, said collapsible holding member collapses when a certain force is applied by the needle shield, and whereby further movement of said needle shield activates said activation means, which in turn releases said force means initiating an injection of medicament.

An earth energy transfer system with a moving energy transfer fluid, the system for transferring energy for an entity, the system, in certain aspects, having apparatus and related items for measuring an amount of energy transferred for the entity to or from the moving energy transfer fluid, and apparatus and related items for invoicing the entity for the amount of energy transferred. The system, in certain aspects, including apparatus and related items for calculating a price for the amount of energy transferred, said invoicing based on said price. The system, in certain aspects, including apparatus and related items for transmitting a signal indicative of a measured amount of energy transferred from the apparatus and related items for measuring to the apparatus and related items for invoicing. Methods are disclosed for using such systems to measure and calculate an amount of energy transferred and / or to invoice an entity for the transferred energy.

A light application unit for a combined photodynamic diagnosis and photodynamic therapy of non-malignant diseases of a parodontium and a tooth of a living being having administered a pharmaceutical preparation allowing the photodynamic diagnosis and the photodynamic therapy comprises a light source, a focusing unit for focusing light emitted by the light source, at least one element arrangeable in a light beam path of the light, and at least one wave guide for transmitting the light from the light source to a distal emitting end, the wave guide is configured rigidly in at least a distal handling end section thereof and being curved in a distal end section.

A detectable pavement warning assembly includes a web having a plurality of projections attached to one another by linear connectors, a planar cover with a series of apertures for receiving the projections therethrough and an adhesive sheet. In use a rigid substrate such as a sidewalk is selected, and a primer is applied. The web, cover and adhesive sheet all pre-assembled are placed on the primed substrate. Next, the warning assembly is heated with an open flame to soften and fuse the pavement warning assembly with the primed substrate. The projections will remain extended sufficiently above the cover to provide a warning to pedestrians that walk thereon, such as when approaching a traffic area or other hazard.

The present invention provides a torsional energy control assembly and method for eliminating slip-stick and / or drill bit oscillations comprising axial and / or rotational oscillations. In one preferred embodiment, the assembly permits slippage between an upper portion of the drilling string and a lower portion of a drill string. The rotational control assembly may be installed at any desired position in the drill string. The rotational control assembly could also be utilized as a component of other drilling mechanisms such as a downhole drilling motor. The rotational control permits slippage while drilling for a selected time or selected rotational distance or other criteria to thereby release torsional energy in the drilling string which otherwise may produce damaging slip-stick torsional oscillations such as slip-stick. The rotational control assembly may, in one embodiment, comprise an on-off clutch whereby torque is either substantially completely transmitted or substantially not transmitted through the assembly for brief periods.

The object of the invention to provide a recording ink with excellent discharge stability and storage stability, which rapidly penetrates into a recording medium and forms a coating, and which will never generate smearing upon high-speed printing or double-sided printing, and which excels in marker resistance, and which enables high quality image recording with less bleeding, and the ink cartridge, the ink record, the inkjet recording apparatus, and the inkjet recording method using the recording ink. The recording ink containing at least water, a colorant, a resin fine-particle, a water-soluble organic solvent and a penetrant, in which the penetrant is a diol compound whose carbon number is 7 to 11 and the resin fine-particle is a silicone modified acrylic resin not containing a hydrolyzable silyl group.

Provided herein is an aqueous ink, which is excellent in both image density and fixing ability irrespective of the kind of a recording medium even when the volume of an ink droplet is small and has such excellent properties that white stripes are not caused even when high-speed recording is conducted. The aqueous ink comprises at least water, a water-soluble organic solvent, a water-insoluble coloring material, a surfactant and a poor medium for the water-insoluble coloring material and / or a salt. The dynamic surface tension of the aqueous ink at a lifetime of 50 milliseconds determined by a maximum bubble pressure method is higher than 47 mN / m, and the dynamic surface tension at a lifetime of 5,000 milliseconds determined by the maximum bubble pressure method is 38 mN / m or lower.

A system and method for simultaneously installing a pipe loop and a grout pipe in a wellbore has been invented which, in one aspect, is used to grout the wellbore by releasing the grout pipe from the pipe loop or from a bottom member connected with the pipe loop and then introducing grout through the pipe into the wellbore as the grout pipe is removed upwardly from the wellbore. In one aspect the system has a curved member or members or a ball or part thereof at the bottom of the pipes to facilitate movement of the system through a wellbore.

The invention discloses a water-based metal cutting liquid. The water-based metal cutting liquid is prepared from raw materials in percentage by mass as follows: 2%-7% of an antirust agent, 0.2%-2% of a corrosion inhibitor, 10%-20% of organic alkali, 20%-45% of an oleate lubricant, 2%-7% of amide, 2%-6% of an emulsifier, 4%-9% of an oiliness agent, 0%-5% of a coupling agent, 0%-3% of a softener, 1%-5% of a sterilizing agent, 0.1%-2% of a defoaming agent and the balance of water. The water-based metal cutting liquid provided by the invention contains no sulfur, phosphorus, chlorine or boric acid and is efficient, environment-friendly and recyclable.

Hypotonic formulations were evaluated for delivering water-soluble drugs and for drug delivery with muco-inert (that is, non-adhesive) mucus-penetrating nanoparticles (MPP). Hypotonic formulations markedly increased the rate at which drugs and MPP reached the epithelial surface, including deep into the vaginal folds. Minimally hypotonic formulations, preferably ranging from 20-220 mOsm / kg, provided rapid and uniform delivery of MPP to the entire vaginal surface, with minimal risk of epithelial toxicity. Data also show that there is a higher osmolality in the colon, such that vehicles with an osmolality above that of blood plasma (generally considered isotonic at ˜300 mOsm / kg), still lead to improvements in distribution in the colon due to rapid, osmotically-induced fluid absorption. The range for improved colon distribution with a hypotonic vehicle in the colon is ˜20 mOsm / kg-450 mOsm / kg.

An earth energy transfer system with a moving energy transfer fluid, the system for transferring energy for an entity, the system, in certain aspects, having apparatus and related items for measuring an amount of energy transferred for the entity to or from the moving energy transfer fluid, and apparatus and related items for invoicing the entity for the amount of energy transferred. The system, in certain aspects, including apparatus and related items for calculating a price for the amount of energy transferred, said invoicing based on said price. The system, in certain aspects, including apparatus and related items for transmitting a signal indicative of a measured amount of energy transferred from the apparatus and related items for measuring to the apparatus and related items for invoicing. Methods are disclosed for using such systems to measure and calculate an amount of energy transferred and / or to invoice an entity for the transferred energy.

Bottom members for a heat loop for an earth energy transfer system with a moving energy transfer fluid and heat loops with such a bottom member; the bottom member in one aspect including a body with a top surface and a bottom surface, the body configured for connection at a lower end of the heat loop, the bottom surface shaped to facilitate passage of the heat loop through a borehole extending down into the earth.

An oily inkjet ink comprises a pigment, a pigment dispersant, and a solvent, wherein the solvent contains a hydrocarbon type solvent (A), a solvent (B) having at least an ester group and an ether group in one molecule, and a solvent (C) that is soluble in the hydrocarbon type solvent and the solvent having at least an ester group and an ether group in one molecule.

This invention provides a leakage test method and a device including: marking a basic tendency of an underground line to be tested, injecting a tracer gas in a certain pressure composition of 5% hydrogen and 95% nitrogen to the line, testing the H2 signal along the tendency of the pipeline with a H2-sensitive probe of a movable hydrogen leak detector, converting the test signal to an electric signal then converting it to a digital signal by A / D conversion, memorizing and analyzing the continuously tested digital signals to judge the leakage orientation based on the change trend weak or strong of the test signal and judging the accurate position of the leak point by comparing with the maximum value of the memory and an indicator displays the maximum value of the concentration of the tested hydrogen and indicates the location of the direction and leakage definitely. Advantage: direct indication, accurate location to reduce work intensity of test.

The invention provides a wood antiquing agent, which is prepared by mixing the following raw materials in percentage by mass: 1 to 10 percent of K2CO3, 0.1 to 1 percent of KMnO4 and the balance of water. The wood antiquing agent can rapidly permeate in wood fibers to give an ancient feeling after the surface of wood is brushed, spray-coated or impregnated with the wood antiquing agent, so that the added value of a product is increased; a process is simple, and the wood antiquing agent is low in cost, and can be widely applied to the manufacturing and repair of ancient furniture, ancient wooden crafts and ancient building door and window components.

The invention relates to a specific antibody directed against, for use for treating graft versus host disease.

The invention relates to lubricating rust preventive oil and application thereof, mainly aiming to solve the problems of the prior art that: a rustproof product has poor adhering property; and the prior art only lays stress on rustproof property and does not attach equal importance to the extreme pressure property, oxidation resistance and permeability of a petroleum product. The lubricating rust preventive oil solves the problems better through adopting the following technical proposal that: the compositions in percentage by weight of the lubricating rust preventive oil are: (a) 0.1 to 10 percent of extreme pressure antiwear agent, (b) 0.5 to 15 percent of rustproof agent, (c) 0.5 to 5 percent of oxidation and corrosion inhibitor, (d) 0.1 to 15 percent of viscidity temperature index improver, (e) 0.1 to 12 percent of friction improver and (f) the balance being base oil. The lubricating rust preventive oil can be used in fields such as harbor machinery, excavator, travelling crane, cargo winch and commercial elevator cable.

The present invention relates to a disposable injection device for delivering a dose of medicament, comprising a generally elongated housing (10), a container (14) containing medicament to be injected through a needle (16), force means (34) acting on said container and capable of, upon activation, move said container and said needle for penetration and subsequently expelling medicament through said needle, activating means (26) arranged to activate said force means, characterised in that said activating means comprises a needle shield (12) arranged slidable in relation to said housing, a collapsible holding member (58) connected to the inner end of said needle shield, whereby, upon movement of said needle shield, said collapsible holding member collapses when a certain force is applied by the needle shield, and whereby further movement of said needle shield activates said activation means, which in turn releases said force means initiating an injection of medicament.

There is disclosed a sanitary tampon including an absorber including: an absorbent layer made of an absorbent fibrous material; and a hydrophobic liquid-permeable layer covering the absorbent layer. The absorber is formed firstly into a flat shape and then into a column shape. The absorbent layer forming the flat absorber is formed with a plurality of small recesses which open in the surface of the absorbent layer and extend into the absorbent layer.

A Peripheral Intravenous Safety Catheter with Quick, Painless Puncture System (PISCQPPS) and a cannula with a retractile needle mounted in a manually operated bellows mechanism to prevent re-use, avoid accidental perforation and ensure safe disposal. This PISCQPPS offers the advantages of reducing or eliminating pain; reducing the possibility of multiple perforation; reducing the need for experience and technical know-how in the matter of injection; being fitted with a safety system; and easy to use. The PISCQPPS consists of two sequential operating systems - namely, a painless insertion system that is located inside a case, consisting of a catheter, a catheter holder, a trigger guard, a trigger-guard holder, a catheter-holder tube, a cannula, a cannula holder, a spring, a filter holder, and a filter; along with a safety system inside whose case the cannula holder, the cannula and the bellows all operate at the same time.

The present invention provides a method for producing a pretreated or hydrolyzed lignocellulosic feedstock. The method comprises feeding a lignocellulosic feedstock to a plug formation device and forming a feedstock plug therein. The plug or segments thereof are fed into an elongate chamber that comprises steam addition means for direct steam addition and a rotating shaft mounted co-axially within the chamber having one or more disintegrating elements mounted on it. Disintegrated feedstock particles are produced in the elongate chamber by the disintegrating elements. The disintegrated feedstock particles are heated by contact with the steam introduced through the steam addition means. The disintegrated feedstock particles are then treated in a reactor to produce the pretreated or hydrolyzed lignocellulosic feedstock. Further provided is a feedstock composition comprising disintegrated feedstock particles. Also provided are methods for reducing erosion on equipment by maintaining the discharge consistency from the plug formation device below 35 wt %.

The invention belongs to the field of coatings for architectural ornament, and particularly relates to an outdoor waterborne woodenware penetration paint and a preparation method thereof. The penetration paint is prepared from the following components by weight: 10 to 15 parts of water, 65 to 80 parts of waterborne emulsion, 2 to 5 parts of coalescing agent, 2 to 25 parts of coloring agent and 4.5to 9 parts of other aids. The outdoor waterborne woodenware penetration paint prepared by the method has good base material closing property, excellent weather fastness and water resistance on the basis of a traditional woodenware paint; in addition, the cracking of a substrate can be reduced and the substrate can be protected from being corroded to a certain extent.

The invention discloses stereoscopic nonwoven fabric with a pore structure, comprising protrusion areas, recess areas and the pore structure. The protrusion areas and the recess areas are defined on the basis of a nonwoven application surface; fiber density from the protrusion areas to the recess areas is gradient, namely the fiber density of the edges from the protrusion areas to the recess areas is higher than that of the tops of the protrusion areas; the edge fiber density is 1.5-30 times of the top fiber density of the protrusion areas; the fiber density of the recess area is 1.5-20 times of the top fiber density of the protrusion areas; a height difference between the protrusion areas and the recess areas is larger than 0.2mm; the average area of each single pore of the pore structure is smaller than 20mm<2>, with smaller than 50% of porosity; the area of the protrusion areas accounts for 20-80% of total area of the stereoscopic nonwoven fabric. Pressure resistance of the high-density fiber areas keeps the stereoscopic nonwoven fabric significantly uneven, liquid permeation is quickened, residue is reduced, and the stereoscopic nonwoven fabric is high in permeating speed and is dry, cool and comfortable.