6results about How to "Reduced shear damage" patented technology

The application relates to the technical field of coil coating, and discloses a radiation refrigeration coil coating composition, a coating and application, the coating composition comprises a basecoat composition and a topcoat composition which are arranged independently. The basecoat composition comprises polyvinylidene fluoride resin slurry, hydroxy acrylic resin, heat-reflecting filler and blocked polyisocyanate curing agent; the topcoat composition comprises polyvinylidene fluoride resin slurry, hydroxy acrylic resin, heat-emitting filler and topcoat crosslinking agent. The application sets the unblocking starting temperature of the basecoat curing agent to be lower than the starting temperature of the topcoat crosslinking reaction, realizes gradient crosslinking of a multilayer coating film from bottom to top, and solves the exhaust blistering defect during baking of a thick coating film. The glass transition temperature of the multilayer coating body is controlled to be 35 DEG C to 50 DEG C, the deformation requirement of warm stamping processing is met, and the coating film is prevented from cracking.

The utility model discloses a microbial fermentation device which comprises a tank body, a stirring frame and at least two layers of stirring paddles which are arranged in the tank body and are distributed along the axial direction of the tank body, and the microbial fermentation device has the beneficial effects that fermentation liquor in the tank body can be stirred and aerated through the matched use of the arranged stirring frame and an aeration main pipe, so that the dissolved oxygen transmission efficiency and the mixing uniformity are improved; meanwhile, by arranging the flow guide pipe with the jet flow direction opposite to the rotating direction of the stirring paddle, a reverse strong vortex field can be formed in the tank, so that gas-liquid two phases generate a shearing effect, the retention time of bubbles is prolonged, and the oxygen dissolving efficiency is improved, in addition, due to strong vortexes generated by reverse jet flow, the rotating speed of the stirring frame can be properly reduced; the shearing damage caused by high rotating speed is reduced, and the problems of insufficient dissolved oxygen, low viable bacteria rate and over-high energy consumption in the traditional fermentation device are solved.

The application discloses an exosome purification preparation method and medicinal composition for hemorrhagic stroke, relates to the field of hemorrhagic stroke exosome preparation, and first collects a serum-free culture supernatant of human umbilical cord mesenchymal stem cells, removes complete cells, cell fragments and large-particle-size vesicles in the supernatant by low-speed and medium-speed two-stage pre-centrifugation, concentrates the supernatant through an ultrafiltration tube to obtain an exosome crude extract; the crude extract is loaded into an affinity chromatography column coated with an anti-human thrombin monoclonal antibody, and specific adsorption is performed to remove coagulation-related impurities such as a blood coagulation factor, fibrinogen and prothrombin complex compound in the crude extract. The exosome medicinal composition prepared by the application has no blood coagulation activity impurity residue, can avoid the risk of inducing intracranial secondary hemorrhage after medication, is completely suitable for the special medication safety requirements of hemorrhagic stroke, has high purity, excellent biological activity reservation and no immunogenic adverse reaction risk.

The application discloses a kind of immobilized enzyme, based on the method and device of bio-oil of the enzyme can be reused, the immobilized enzyme is with polyethylene glycol modified Fe3O4 Nanoparticle as matrix, matrix first adsorbs and loads first part free protease, then it is dispersed in sodium alginate aqueous solution with second part free protease and mixed uniformly, sequentially through Ca 2+ Two-step action process of ion hardening and glutaraldehyde crosslinking reaction, the outer sodium alginate reaction forms reticulated macroporous gel microspheres, finally after washing, drying, the microsphere complex of embedding second part free protease and polyethylene glycol modified nano Fe3O4 load immobilized protease is prepared.The stability of the immobilized enzyme in the non-homogeneous slurry mixing system, in-situ separation convenience greatly improves, immobilized enzyme can be better reused, in addition, the stirring paddle of bio-oil reactor is improved, and the stability of immobilized enzyme use can be further improved.

The invention discloses a stirring method for a coated asphalt reactor, which comprises the following steps: an oxidation reaction stage: introducing oxidizing gas into a reaction kettle, controlling a stirring assembly to operate in a first operation state, and utilizing a lower-layer shearing type stirring paddle to provide a shearing effect so as to disperse the gas, a gas-liquid mixed flow field is maintained by utilizing an upper-layer circulating stirring paddle; and a steam stripping stage: stopping introducing the oxidizing gas, introducing a steam stripping medium into the reaction kettle, and controlling the stirring assembly to operate in a second operation state, the stirring strength of the second operation state being lower than that of the first operation state, so as to reduce the shearing effect and maintain the whole kettle circulation, and avoid the situation that bubbles are difficult to escape in a heterogeneous fluid system due to too fine shearing. The large change of the material viscosity can be adapted, and the uniformity and the production stability of the product are improved.

The application discloses a building steel structure bolt anti-loosening self-locking device, and particularly relates to the technical field of bolt anti-loosening self-locking devices, which comprises a fixed ring, an inner ring and a rotating outer ring, the inner wall of the fixed ring is provided with threads for connecting a bolt, and the outer wall of the fixed ring is provided with a ratchet plate through a rotating shaft; the inner wall of the inner ring is provided with a wedge-shaped block which is attached to the ratchet plate; the inner part of the rotating outer ring is provided with a damping cavity filled with silicon-based damping glue, and the outer wall of the rotating outer ring is connected with the inner ring through a connecting buckle. When the device works, the fixed ring is tightened along with the bolt to press the fastening plate and the connecting frame on the steel structure column. If there is a reverse loosening trend, the ratchet plate is pressed along the inclined surface of the wedge-shaped block and abuts against the limiting wall, and the fixed ring is locked instantaneously by using one-way locking; the damping cavity absorbs and dissipates high-frequency vibration. The application combines mechanical locking and damping shock absorption, effectively prevents bolt loosening and fatigue fracture, and significantly improves the connection reliability of steel structure nodes and the construction and maintenance efficiency.