46results about How to "Facilitate delivery" patented technology

Systems that can include a microneedle array and a small molecule metabolic reporter are disclosed. The systems can be used to penetrate the epidermis and monitor the change in concentration of one or more metabolite or analyte.

The present invention relates to delivery of biologically active molecules to cells. Specifically, the invention relates to polycationic compositions, polymers and methods for delivering nucleic acids, polynucleotides, and oligonucleotides such RNA, DNA and analogs thereof, including short interfering RNA (siRNA), ribozymes, and antisense, or peptides, polypeptides, proteins, antibodies, hormones and small molecules, to cells by facilitating transport across cellular membranes epithelial tissues and endothelial tissues. The compositions and methods of the invention are useful in therapeutic, research, and diagnostic applications that rely upon the efficient transfer of biologically active molecules into cells, tissues, and organs.

This invention features conjugates, degradable linkers, compositions, methods of synthesis, and applications thereof, including galactosamine and N-acetyl galactosamine derived conjugates of biologically active compounds, including antibodies, antivirals, chemotherapeutics, peptides, proteins, hormones, nucleosides, nucleotides, non-nucleosides, and nucleic acids including enzymatic nucleic acids, DNAzymes, allozymes, antisense, dsRNA, siNA, siRNA, triplex oligonucleotides, 2,5-A chimeras, decoys and aptamers.

Devices, systems, and methods are disclosed for delivering enhanced message content to subscribers and for overcoming common incompatibilities found in message delivery mechanisms. Exemplary embodiments, of the present subject disclosure profile an intended recipient's network capabilities, the intended recipient's device, and / or the recipient's service feature profile. This profile is leveraged to predictively and adaptively adjust the subsequent enhanced message content delivery process. Further, content modification can be applied for those cases where there is a defined mismatch that can be handled in order to facilitate delivery of the substance of the enhanced content. Finally, in cases where the content needs to be delivered intact to the intended recipient, but where the recipient network, the recipient's device and / or the recipient's service profile do not allow for delivery, the content may be delivered to an alternative device or system. An informational reference vector, such as a Universal Resource Locator (URL), is delivered to the intended recipient's device to locate the content. These alternative devices or systems may be managed by the sender, the recipient, or a service provider's network.

The present system facilitates delivery and pickup of goods by providing a locker module at a location near a customer's residential site. For a vendor to deliver a good to the customer, the vendor leases a unit in the locker module from the system controller by accessing the system controller's website and providing details of the customer and a delivery agent. The vendor then notifies the delivery agent to make the delivery. The delivery agent provides the system controller the particulars of its delivery person. The designated delivery person accesses the leased locker unit using a registered smart card and delivers the good. The system controller notifies the customer of the delivered good. The customer accesses the locker unit containing the good by using a registered smart card.

Apparatus, in the form of a eutectic alloy plug (1) and a deployment heater (10) are provided. The plug (1) and the deployment heated (10) are provided with means (5, 13) for releasably retaining the deployment heater (10) within a cavity (4) in the plug (1). The nature of the retaining means is such that once the plug (1) is secured in a well the heater (10) can be recovered without the plug (1). An extraction heater (20), which is also receivable within the cavity (4) of the plug (1), is provided to re-melt the eutectic alloy and thus enable the extraction of the plug from a well. Various method of plugging abandoned wells are made possible by the control that the provided apparatus gives.

Compositions and methods for preventing or inhibiting the growth of a hyperproliferative lesion in a subject that include a nucleic acid comprised in a solid or semi-solid formation or in a transdermal or transcutaneous delivery device are disclosed. Also disclosed are compositions of a nucleic acid capable of preventing or inhibiting the growth of a hyperproliferative lesion in a subject that include an adhesive. Compositions of a nucleic acid capable of preventing or inhibiting the growth of a hyperproliferative lesion in a subject that include a nucleic acid uptake enhancer are also disclosed. Methods of preventing or inhibiting the growth of a hyperproliferative lesion in a subject that involve these therapeutic compositions and devices are also disclosed.

In a wireless communications network, a system is provided for securely executing the transfer of rights between holders of accounts. The secure transfer of messages may represent the exchange of title to monetary assets. Each title holder is provided with a SIM card containing a transaction application that can interpret menu messages, accept user inputs and generate transaction messages for processing by the system. Each of the menu and transaction messages is delivered as a short messaging service message. The holder inserts his SIM into a mobile handset, and (after authentication with the system) is permitted to interact with the system to conduct rights transfer transactions. Since the transactions are in the form of simple text messages, the mobile handset need not conform to a high specification (i.e. may not support GPRS).

A method of facilitating delivery of traffic messages is disclosed. Data indicating a plurality of traffic conditions on a road network are obtained. For each of the traffic conditions, the data provides a location description. For each of the traffic conditions, the method determines at least one broadcast service area in which the traffic condition is located. A plurality of traffic messages is transmitted. Each traffic message is associated with a broadcast service area code identifying the broadcast service area in which the traffic condition is located.

An anti-aging method and composition are disclosed. The composition is a micro-cluster water having anti-oxidant and free-radical quenching properties. The method involves contacting a cell or portion thereof in danger of free-radical or oxidant damage with the micro-water.

A shipping system for shipping packages involving the coordinated use of at least a first carrier and a second carrier. The shipping system includes physical delivery facilities for the physical delivery of packages, the physical delivery facilities including at least one transfer location at which the second carrier may take over delivery responsibilities for a package. The shipping system also includes an information system having a shipper computer system configured to record and determine whether the delivery address of a package is an efficient destination for the first carrier. If not an efficient destination, such as a delivery address having a rural zip code, the shipper computer system is configured to label the package for delivery to one of the transfer locations, allowing the first carrier to transfer the selected package to the second carrier for completion of the less efficient portion of the delivery.

Support devices and pods for the head and neck region of patients undergoing radiation therapy are provided herein. The pod generally includes a support shell shaped to generally conform to the shape of the head and neck region of the patient, a foam insert that conforms to the head and neck region of the patient, and an immobilization facemask attached directly to the shell, thereby facilitating close placement of the radiation beam delivery device to the patient and reducing any attenuation and perturbation of radiation doses directed at the patient. The components of the pod are made from materials having properties that reduce any attenuation and perturbation of prescribed radiation doses.

A system and method for an on-line swapping service. The service registers members and allows members to list items that each member is willing to swap in exchange for credits with the service for an item from listed by another member. An example of the items that may be swapped using the swapping service is books, such as paperback books. To facilitate delivery through the mail of an item from one member to another member, a printable mailing wrapper is created by the system with the appropriate destination address. The system emails, downloads or otherwise sends the mailing wrapper to the member who is in position of the item to be shipped. That member simply prints the mailing wrapper on a standard printer, and wraps it around the item to be shipped via standard postal services.

A passive transcutaneous bone conduction device configured to deliver externally-generated mechanical vibrations to a bone of a recipient's head, the device comprising: an implantable magnetic coupler configured to be rigidly attached to the bone; and an external vibrator including an actuator having a movable magnetic mass; wherein the movable magnetic mass and the magnetic coupler form a transcutaneous magnetic coupling sufficient to retain the vibrator against soft tissue covering the bone with sufficient force to facilitate delivery of mechanical vibrations from the vibrator to the bone.

A toothbrush assembly including a toothbrush and a toothpaste cartridge. The toothbrush includes: a handle having a compartment to receive the toothpaste cartridge; a head having bristles; a door covering an opening of the compartment; and a conduit running from the compartment to the head to deliver toothpaste from the toothpaste cartridge in the compartment to the head and the bristles. The toothpaste cartridge includes: a housing having a cavity to store toothpaste; a piston having threads; a paste plate coupled to the piston via the threads; a knob coupled to the piston to turn the piston to move the paste plate along the piston toward the head of the toothbrush to dispense the toothpaste from the cavity to through the conduit into the bristles; and an end plate having at least one hole to discharge the toothpaste from the cavity of the cartridge to the conduit of the toothbrush

The invention provides a gas-liquid two-phase atomization cleaning device and relates to the technical field of the semiconductor chip technology. The gas-liquid two-phase atomization cleaning device comprises a gas pipeline, a liquid pipeline and a gas-liquid two-phase atomization nozzle, one end of the gas pipeline and one end of the liquid pipeline are arranged on a swing arm while the other end of the gas pipeline and the other end of the liquid pipeline are communicated with the gas-liquid two-phase atomization nozzle to form atomization particles, and the swing arm drives the gas-liquid two-phase nozzle to reciprocate in a circular arc manner between the edge and the center of a wafer. High-speed liquid flow and high-speed gas flow are sufficiently acted through a gas-liquid two-phase atomization nozzle structure, superfine atomized droplets uniform in particle size are formed by adjusting gas flow rate and liquid flow rate of small flow rate, the superfine atomized droplets are sprayed on the surface of the wafer after being accelerated through the high-speed gas flow, and cleaning is completed. By the arrangement, transferring of impurities in troughs to a main flow body is promoted, efficiency in cleaning is improved, cleaning effect is improved, and damage to the surface structure of the wafer is reduced due to small quality of the atomization particles.

The application discloses a nanoparticle coated lithium ion battery diaphragm and a preparation method thereof. The nanoparticle coated lithium ion battery diaphragm comprises a basal membrane and nanoparticles coated on at least one surface of the basal membrane, wherein the nanoparticles have porous structures, and at least a part of channels penetrate the surface of the nanoparticles. The nanoparticle coated lithium ion battery diaphragm employs the nanoparticles with the porous structures to prepare a coating, the nanoparticles with the porous structures have developed channel structures,lithium ions can diffuse in gaps between nanoparticles, and lithium ions can freely diffuse in the internal channels in the porous structures of the nanoparticles, in order to improve porosity of thediaphragm with the nanoparticle coating, and improve wettability of diaphragm electrolyte. The nanoparticle coated lithium ion battery diaphragm keeps heat resistance of the traditional diaphragms with nanoparticle coatings, and at the same time improves conductivity of lithium ions, so that batteries have high rate performance and long circulation performance.

A glycolipopeptide comprising a carbohydrate component, a peptide component and a lipid component, for use as a therapeutic or prophylactic vaccine. Also provided are monoclonal and polyclonal antibodies that recognize the glycolipopeptide of the invention, as well as uses thereof.

Media content associated with a playlist is provided for remote access over a packet-based network. According to an example embodiment of the present invention, a host server provides access to a user-defined playlist depicting media content available from user's media content source (e.g., at a registered user's PC). User-defined playlists and associated media content are managed to facilitate access to media in accordance with characteristics of the media content and / or playlist such as format and bitrate, and as may be related to an intended playback use of the playlist. Media content for the playlists is stored in a network storage device for remote access, with the storage managed to facilitate remote access in appropriate formats, with selective cross-referencing among playlists for different playlist types, content format and content bandwidth.

A guidewire navigable through body vessels of a human subject for delivery of a catheter or the like is provided. The guidewire includes an expandable segment movable between a collapsed state and an expanded state. If the catheter encounters resistance in a vessel and cannot be advanced further, the medical professional can move the expandable segment to the expanded state in which the expandable segment engages an inner surface of the catheter. The expandable segment locks onto the catheter, which allows the guidewire and catheter to be advanced through the vessel together as a single unit. An inflatable balloon catheter movable along the guidewire requires only a single tube and is sealed by the expandable segment of the guidewire for subsequent inflation.

Various systems, methods, and apparatuses are described for locating a patron and delivering an order. One example method may comprise detecting a mobile device of a customer at an establishment. The example method may further comprise determining a location of the mobile device of the customer within the establishment. The example method may further comprise linking the determined location to an order placed by the customer. The example method may further comprise enabling delivery of the order to the customer at the determined location. Similar and related methods, apparatuses, systems, and computer program products are also provided.

Electrical systems and related methods are disclosed. An electrical system includes a wearable mobile electronic device including cellular voice equipment configured to enable a user to participate in cellular voice calls, cellular data equipment configured to enable the wearable mobile electronic device to communicate through a cellular data network, one or more biometric sensors, and at least one audio speaker. A method includes selecting audio media based, at least in part on biometric information, and providing, with a remote server, data corresponding to the selected audio media to the wearable mobile electronic device through a cellular data network. An electrical system includes a wearable mobile electronic device including control circuitry configured to interact with a remote server to together provide smart mobile electronic device features to a user through the wearable mobile electronic device, wherein the control circuitry is alone insufficient to provide the smart mobile electronic device features.

A print media feed system for media of variable thickness having a slanted loading platform with drive wheels to direct print media to a feed zone having a belt system and hanging friction wheels to draw out single print medium of varying thickness and feed the medium to a print zone for a ink jet, laser or other printer wherein the print zone includes a floating deck to maintain a constant clearance distance between the printhead and the print medium.

A transdermal drug delivery patch with an array of spatially organized reservoirs. The invention provides greater penetration of drug into the skin compared to current transdermal drug delivery systems, and facilitates the delivery of drugs that are presently refractory to transdermal delivery due to high molecular weight.

A refilling apparatus for a refillable container and associated methodology is described and wherein the apparatus includes a refillable dispensing container; a source of pressurized propellant for delivery to the refillable dispensing container; a valve coupled in fluid flowing relation relative to the source of pressurized propellant; a source of a liquid to be dispensed by the refillable container and which is coupled in fluid flowing relation relative to the valve, and a pressurized vessel positioned downstream relative to both the sources of the liquid to be dispensed, and the pressurized propellant, as well as the valve, and which encloses a volume of the liquid to be dispensed to refill a depleted refillable dispensing container when the refillable dispensing container engages the valve.

The presence of a cardiac pulse in a patient is determined by evaluating fluctuations in an electrical signal that represents a measurement of the patient's transthoracic impedance. Impedance signal data obtained from the patient is analyzed for a feature indicative of the presence of a cardiac pulse. Whether a cardiac pulse is present in the patient is determined based on the feature in the impedance signal data. Electrocardiogram (ECG) data may also be obtained in time coordination with the impedance signal data. Various applications for the pulse detection of the invention include detection of PEA and prompting PEA-specific therapy, prompting defibrillation therapy and / or CPR, and prompting rescue breathing depending on detection of respiration.

An information marketplace is provided in which information items are received from various sources. Each item and the item providers carry descriptors that identify various attributes of the information being provided and by whom it is being provided. Requests for information are received from information consumers that are also tagged with attributes describing the consumer and the information being requested. A subset of the information available in the marketplace is provided to the consumer based on a degree of match among the characteristics describing the information, the attributes associated with the provider of the information, and the attributes associated with the consumer without identifying the actionable investment opportunity to the information consumer or identifying the information consumer to the information provider.

The invention relates to a preparation method of a three-dimensional ordered mesoporous MOF material. The preparation method comprises the following steps of: the step A, preparing polystyrene PS microspheres; the step B, preparing a three-dimensional ordered mesoporous zif8 material; B1, dispersing a proper amount of zinc nitrate hexahydrate into methanol to obtain a solution A, dispersing a proper amount of 2-methylimidazole into methanol to obtain a solution B, adding the solution B into the solution A, adding 1-2g of PS microspheres obtained in the step A for uniform stirring, sealing, standing and aging; B2, sequentially adopting methanol and ethanol as solvents after centrifuging, and respectively washing for three times; drying the solid and liquid to obtain a 3Dzif8 material with an ordered mesoporous structure; the step C, carbonizing the 3Dzif8 material; putting the 3Dzif8 material in the step B2 into a tubular furnace, performing carbonizing at a high temperature in Ar / H2 mixed gas, and performing cooling to a room temperature to obtain the CNT-3Dzif8. According to the preparation method, the 3D ordered zif8 material is prepared by adoption of a template method, and thethree-dimensional ordered ZnS material is prepared after carbonization, so that the electrochemical performance of the lithium ion battery is improved.