1545results about "Medical preparations" patented technology

The invention relates to a zirconia-based all-ceramic false tooth and a preparation method thereof. A core layer of the zirconia-based all-ceramic false tooth is prepared from the following components in parts by mass: 90 to 94 parts of ZrO2, 5 to 9 parts of Y2O3, 0.1 to 0.5 part of Al2O3, 0.01 to 0.5 part of Fe2O3, 0.01 to 0.5 part of Er2O3 and 0 to 0.2 part of MnO2, and a shell layer of the zirconia-based all-ceramic false tooth is prepared from the following components in parts by mass: 24.5 to 49.5 parts of CaCO3, 45 to 50 parts of SiO2, 0 to 25 parts of MgO, 0.01 to 0.5 part of Fe2O3, 0.01 to 0.5 part of Er2O3 and 0 to 0.2 part of MnO2. The preparation process comprises the following steps: performing dry pressing and isostatic pressing on raw materials of the core layer, presintering, and carving to obtain a zirconia-based false tooth biscuit; meanwhile, calcining raw materials of a shell layer, then adding deionized water, a dispersing agent and an adhesive, and carrying out ball milling and mixing to obtain calcium-magnesium-silicon-based ceramic slurry; and coating the calcium-magnesium-silicon-based ceramic slurry on the surface of the zirconium oxide-based false tooth biscuit, and sintering to obtain the zirconium oxide-based all-ceramic false tooth provided by the invention. The zirconia-based all-ceramic false tooth has good jade texture and is closer to the natural color of natural teeth.

The invention discloses a method for preparing a light-transmitting gradient multicolor zirconium oxide material through photocuring, which comprises the following steps: preparing modified aluminum oxide which is formed by attaching a strontium element and a chromium element to the surface of aluminum oxide; preparing bottom-layer slurry, middle-layer slurry and upper-layer slurry from the zirconium-aluminum powder; the bottom layer slurry comprises zirconium aluminum powder and a coloring agent; the middle layer slurry comprises zirconium-aluminum powder, a light-transmitting auxiliary agent and a coloring agent; the upper-layer slurry comprises zirconium-aluminum powder, a light-transmitting auxiliary agent and a coloring agent; preparing a bottom layer green body by using the bottom layer slurry through 3D printing by using the photocuring slurry, preparing a middle layer green body on the surface of the bottom layer green body by using the middle layer slurry, and preparing an upper layer green body on the surface of the middle layer green body by using the upper layer slurry, so as to obtain a zirconium oxide material green body; the light-transmitting gradient multicolor zirconia material with gradient light transmission and gradient color is directly prepared through 3D printing, the color of the light-transmitting gradient multicolor zirconia material is closer to that of real teeth, and the strength and toughness are not reduced.

The present invention provides an adhesive composition for stereolithographic articles and non-stereolithographic articles, possessing excellent adhesive properties to both objects fabricated by stereolithography and molded articles made by methods other than stereolithography. The present invention relates to an adhesive composition for stereolithographic articles and non-stereolithographic articles, comprising: a polyfunctional (meth)acrylic polymerizable monomer (A); and an organic solvent (B) having a normal boiling point of 120° C. or less, and a viscosity at 25° C. of 10 mPa·s or less, wherein the polyfunctional (meth)acrylic polymerizable monomer (A) comprises two or more polymerizable groups per molecule, and at least one selected from the group consisting of a urethane bond, an aromatic skeleton, and an amide bond, and the polymerizable groups of the polyfunctional (meth)acrylic polymerizable monomer (A) are (meth)acryloxy groups or (meth)acrylamide groups.

The invention provides a granulation raw material, a pre-sintered body, a zirconia porcelain block, a fast firing production method and application. The fast firing production method comprises the following steps: S1, providing a first zirconium oxide material and a second zirconium oxide material; s2, compounding the first zirconium oxide material and the second zirconium oxide material, and granulating together with an auxiliary material to obtain a granulation raw material; s3, obtaining a green body based on the granulation raw materials; s4, carrying out pre-sintering treatment on the green body to obtain a pre-sintered body; and S5, machining the pre-sintered body, and then carrying out fast firing treatment to obtain the zirconium oxide porcelain block. On the basis of compounding of granulation raw materials, the overall performance of the zirconia ceramic block can be improved while a pre-sintered body can be rapidly sintered.

The invention discloses a double-component reinforced 5Y-PSZ dental ceramic material and a preparation method thereof, and relates to the technical field of ceramic material preparation. The method comprises the following steps: mixing ZrCl4 and deionized water, and dropwise adding an ammonia water solution to prepare m-ZrO2 nano ceramic powder; zrOCl2. 8H2O, Y (NO3) 3.6 H2O and deionized water are mixed, the m-ZrO2 nano ceramic powder and polyethylene glycol 2000 are added, and the material is prepared through calcination, spray granulation, hot-pressing presintering and high-temperature sintering. According to the 5Y-PSZ dental ceramic material disclosed by the invention, the nano-scale m-phase ZrO2 is adopted as a reinforcing material and is dispersed and distributed inside the 5Y-PSZ, and through volume expansion generated by t-m phase change of the m-phase ZrO2, the anti-aging performance is guaranteed, and meanwhile, the reinforcement of the 5Y-PSZ dental ceramic material is realized. The invention solves the problem of insufficient strength of the 5Y-PSZ dental ceramic material in the prior art.

A photocurable composition, contains a (meth)acrylic monomer component, and photopolymerization initiator, in a case in which a rectangular sheet-like test piece A1 with a length of 40 mm, a width of 10 mm, and a thickness of 1.0 mm is produced by photomodeling under conditions in which the photocurable composition is irradiated with visible light having a wavelength of 405 nm at an irradiation dose of 11 mJ / cm2 to form a cured layer A1 with a thickness of 50 μm, the cured layer A1 is stacked in a thickness direction thereof to form a rectangular sheet-like modeling product A1 with a length of 40 mm, a width of 10 mm, and a thickness of 1.0 mm, and the modeling product A1 is irradiated with ultraviolet rays having a wavelength of 365 nm at an irradiation dose of 3 J / cm2 to produce the test piece A1.

The invention discloses silk fibroin-sodium alginate-chitosan bionic leather and a preparation method and application thereof.The preparation method comprises the following steps that a silk fibroin solution and a sodium alginate solution are mixed, after calcium salt is added, a chitosan solution continues to be added and mixed with waterborne polyurethane, and a mixed solution is obtained; and carrying out surface activation treatment on base cloth, coating the activated base cloth with the mixed solution, and carrying out drying curing and ultrasonic lamination to obtain the silk fibroin-sodium alginate-chitosan bionic leather. The silk fibroin, sodium alginate and chitosan bionic leather prepared by the invention not only has high strength and good ductility, but also has excellent tensile strength, folding resistance and wear resistance, and also has good biodegradability, so that the burden of waste post-treatment on the environment can be reduced, and the raw material cost and post-treatment cost of the bionic leather can be remarkably reduced; the method has both environmental benefits and outstanding economic benefits.

The present invention relates to: a photocurable restoration composition comprising a ceramic composition; and a dental prosthesis using a 3D printer. More specifically, the present invention relates to: a photocurable restoration composition comprising a silane-treated ceramic composition; and a dental prosthesis manufactured using the photocurable restoration composition by using a 3D printer. According to the present invention, it is possible to obtain a dental prosthesis having improved gloss, excellent thermal resistance and hardness, and improved uniformity and reliability.

The invention discloses a synergistic phase change reinforced dental zirconia material and a preparation method and application thereof, and relates to the technical field of ceramic materials.The preparation method comprises the following steps that a zirconium oxychloride solution and a polyvinyl alcohol solution are mixed, dried and then subjected to heat treatment, and ZrC ceramic powder is obtained; then mixing with yttria-stabilized zirconia (Y-PSZ) to obtain composite powder; the composite powder is subjected to hot pressing sintering and cooling, and a pre-sintered body is obtained; introducing Ar-O2 mixed gas, and carrying out controllable oxidation to obtain an oxidation phase change reinforced pre-sintered body; and carrying out high-temperature sintering to obtain the synergistic phase change reinforced dental zirconia material. The invention further discloses the synergistic phase change reinforced dental zirconia material and application of the synergistic phase change reinforced dental zirconia material in preparation of dental products. According to the method, ZrC is introduced, and a pressure stress field formed by crystal transformation in ZrC oxidation and high-temperature sintering processes is utilized, so that the yttrium oxide stabilized zirconia dental ceramic is strengthened, and the mechanical strength of the yttrium oxide stabilized zirconia dental ceramic is remarkably improved.

To provide a calcined body that is processed easier than a conventional calcined body and where differences in hardness between production lots are suppressed.SOLUTION: A calcined body comprises: at least one first transition metal element selected from the group consisting of manganese (Mn), iron (Fe), cobalt (Co), nickel (Ni), copper (Cu), molybdenum (Mo), technetium (Tc), ruthenium (Ru), rhodium (Rh), palladium (Pd), and silver (Ag); a coloring element of at least one of a lanthanoid rare earth element and a second transition metal element different in kind from the first transition metal element; and zirconia containing a stabilizing element. A content of the first transition metal element is 100 mass.ppm or more, a content of the second transition metal element is less than 100 mass.ppm, and an absolute value of a difference in hardness relative to a hardness of a calcined body obtained from a commercially available powder is 10 HV or less.SELECTED DRAWING: None

The invention discloses antibacterial glaze paste for a ceramic false tooth and a preparation method thereof, and belongs to the technical field of antibacterial glaze paste manufacturing, the antibacterial glaze paste for the ceramic false tooth comprises: 70-95% of glaze powder matrix composed of feldspar, quartz, kaolin and calcium carbonate; the antibacterial agent is composed of zinc oxide and bismuth oxide, the molar ratio of the bismuth oxide to the zinc oxide is 5%-18%, the surfaces of particles of the antibacterial agent are coated with a plurality of silicon dioxide shell layers, the thickness of the shell layers is 3-15 nm, and the shell layers are treated through a coupling agent; the antibacterial agent can further contain a trace amount of silver or copper nanoparticles with the mass fraction of 0.01-0.3%, and through the synergistic effect of zinc oxide and bismuth oxide, limited release of multiple SiO2 shell layers and addition of a trace amount of Ag / Cu, the ceramic false tooth antibacterial glaze paste can keep efficient antibacterial ability for a long time without external illumination or special excitation conditions, the antibacterial rate is larger than or equal to 98%, and the antibacterial effect is good. The method is obviously superior to uncoated or single-step sintered contrast samples.

A dental adhesive material kit may have desirable adhesive properties for tooth structure, and, while ensuring appropriate strength, may allow easy removal of excess cement in a semi-cured state created by temporarily applying light to excess portions of cement with a photoirradiator. Such a dental adhesive material kit may include a dental aqueous adhesive composition (A) and a dental curable composition (B), satisfying the inequality (I)0≤t2−t1≤3.0  (I),wherein t1 (min) is a contactual polymerization start time of the dental aqueous adhesive composition (A) and the dental curable composition (B), and t2 (min) is a polymerization start time of the dental curable composition (B).

The invention discloses an application of monocalcium aluminate in a premixed dental filling material, the premixed dental filling material and a preparation method of the premixed dental filling material, the premixed dental filling material takes monocalcium aluminate as a main hydraulic material, calcium oxide is supplemented as a curing accelerator and an expanding agent, and the premixed dental filling material can also comprise calcium pyrophosphate, calcium carbonate, calcium carbonate and calcium carbonate. The biological hydrogel paste with excellent injectable performance is prepared. The material keeps fluid under a sealed condition, and is hydrated, solidified and hardened after being placed in a physiological environment and contacted with physiological body fluid. According to the present invention, by using the excellent biocompatibility and the biological activity of the monocalcium aluminate, the premixed aluminate hydrogel dental filling material is prepared from the monocalcium aluminate, and can be used for medical applications and dental applications, including the fields of pulp capping, root canal therapy, hard tissue repair and the like.

The invention discloses light-cured resin, a preparation method and application, and belongs to the technical field of light-cured 3D printing. The light-cured resin provided by the invention comprises the urethane acrylate oligomer, the modified acrylate oligomer and the reactive diluent, and the urethane acrylate oligomer can improve the toughness and reaction speed of the light-cured resin and reduce the volume shrinkage of the light-cured resin, so that the light-cured resin has good light-cured effect. The modified acrylate oligomer can improve the durability of the light-cured resin, adjust the hardness and toughness and reduce the volume shrinkage of the light-cured resin, and the reactive diluent can improve the hardness and toughness of the light-cured resin; the polyurethane acrylate oligomer, the modified acrylate oligomer and the reactive diluent are compounded, and the dosage of each component is limited, so that each component fully plays a synergistic role, and the light-cured resin has low volume shrinkage and high hardness, and keeps high toughness and durability at the same time.

A composite, three-dimensionally stable facing material for adding aesthetic features to a denture base. The composite may be a flexible, flat strip of material capable of being molded to gingival surfaces of the denture base and retained on the denture base. The strip is capable of being trimmed and then cured to a hardened state. Fibers and / or other characterization may be added for increasing realism of the denture gingival surfaces.

The invention relates to glass powder as well as a preparation method and application thereof. The glass powder is prepared from raw materials including an inorganic mixture and glass clinker, by taking the total mass of the preparation raw materials of the glass powder as 100wt%, the percentage contents of the inorganic mixture and the oxides contained in the glass clinker are as follows: 40wt%-54wt% of SiO2, 5wt%-9wt% of Al2O3, 10wt%-30wt% of SrO, 5wt%-8wt% of B2O3, 5wt%-15wt% of ZrO2, 0wt%-5wt% of CaO, 1wt%-8wt% of MgO, 1wt%-2wt% of Y2O3 and 0wt%-5wt% of a sodium-potassium mixture. The glass powder provided by the invention does not contain barium element, and has good biological safety, X-ray developing capability and low-temperature chemical stability. According to the preparation method provided by the invention, impurities are prevented from entering the glass powder, and the glass powder is high in quality and good in batch stability.

The invention relates to a light-cured dental resin adhesive containing a silane coupling agent modified monomer as well as preparation and application of the light-cured dental resin adhesive. The dental resin adhesive comprises a resin matrix, an organic polymer and a photoinitiator, wherein the resin matrix consists of methacrylate resin grafted and modified by a silane coupling agent and unmodified methacrylate resin. According to the method, the isocyano group of the silane coupling agent is selected to react with the hydroxyl group on the resin monomer to generate the silane modified grafted resin monomer, and the method is simple, low in equipment requirement and suitable for large-scale production; the obtained dental resin adhesive can be internally covalently cross-linked to enhance the self mechanical property, can also be chemically bonded with a bonding substrate by utilizing a grafted silane coupling agent to improve the interface bonding strength, is especially suitable for being used as an enamel bonding material, and can remarkably improve the service life and the curative effect of a bonded restoration.

The present invention relates to methods for curing polymeric dental appliances comprised of partially cured photopolymerizable components, especially for additively manufactured denture base and artificial tooth components utilized in the production of full and partial dental prostheses. In particular, the invention relates to methods of utilizing a curing apparatus having one or more controllable heating sources and one or more controllable LED light sources to achieve specific preheating and light curing conditions for more effectively converting partially cured photopolymerizable components from a partially cured state to a final cured state.

The present invention provides a method for manufacturing a dental prosthesis in which defective baking of a porcelain material is suppressed by using a zirconia composite sintered body that contains Nb2O5 and / or Ta2O5. The present invention relates to a method for manufacturing a dental prosthesis, the method comprising a step for performing a heat treatment or a polishing treatment as a pretreatment on a zirconia composite sintered body that contains Nb2O5 and / or Ta2O5, and a step for building up a porcelain material on the pretreated zirconia composite sintered body and performing firing.

The invention provides a tooth patch for repairing tooth hardness and a preparation method thereof, the tooth patch comprises a support material and gel, and the gel comprises the following components by mass: 1.5-2 parts of regenerated silicon, 0.5-0.7 part of A200, 1.5-2.5 parts of a thickener, 15-20 parts of a film-forming agent, 4-6 parts of a humectant, and 1-1.5 parts of a gelling agent. The tooth paste can form a hydroxyapatite layer on the tooth surface, repair tooth enamel, promote remineralization of the tooth surface and improve tooth hardness, is alkalescent, and can prevent dental caries; after contacting with saliva, hydroxyapatite crystals can be quickly formed in dentinal tubules to block the dentinal tubules, and the hydrogel can be used for treating tooth sensitivity.

The invention belongs to the technical field of biomedical materials, and particularly relates to a mesoporous silica functional filler and a preparation method thereof, and a composite resin material and a preparation method and application thereof. The mesoporous silica functional filler provided by the invention has remineralization performance and pH response type. Functional modification is carried out on the surface of mesoporous silica, the modified mesoporous silica can load phosphorylated chitosan / amorphous calcium phosphate through electrostatic attraction, and the pH response performance is given to the modified mesoporous silica. The phosphorylated chitosan can simulate the effect of dentin matrix protein 1, can regulate the remineralization process of dentin, and can chelate calcium ions to stabilize amorphous calcium phosphate in the solution to form an amorphous nano precursor. The polyelectrolyte may be replaced with a biomimetic analog to initiate the remineralization process. The size of the mineral precursor and the deposition sequence and layer of the mineral precursor inside and outside the collagenous fiber can be regulated and controlled, and meanwhile nucleation and growth of apatite crystals inside and outside the collagenous fiber can be promoted.

The present invention provides a zirconia composite sintered body which has suitable strength for dental use, which has excellent mechanical workability in a sintered body state, and which has excellent aesthetic properties. The present invention relates to a zirconia composite sintered body comprising: zirconia; a stabilizer which is capable of suppressing a phase transition of the zirconia; and Nb2O5 and / or Ta2O5, said zirconia composite sintered body comprising a plurality of layers which differ in terms of the content of at least one component from among the stabilizer, the Nb2O5, and the Ta2O5, with respect to the total amount, in moles, of the zirconia, the stabilizer, the Nb2O5 and the Ta2O5.

The present invention provides: a zirconia composite sintered body that can be machined and exhibits exceptional adhesiveness without sandblasting being performed after machining; and a dental preservation repair kit including the zirconia composite sintered body. The present invention relates to a dental zirconia composite sintered body containing monoclinic zirconia, the abundance ratio fm of monoclinic systems represented by formula (1) being higher than 10% and not higher than 60%.　Formula (1): fm = I28 / (I28 + I30) × 100 (In the formula, fm represents the abundance ratio (%) of monoclinic systems, I28 represents the area intensity of a peak around 2θ = 28° where a monoclinic main peak appears in XRD measurement, and I30 represents the area intensity of a peak around 2θ = 30° where a tetragonal or cubic main peak appears in XRD measurement).

The invention provides a rapid sintering method of zirconia ceramic for dentistry and zirconia ceramic, the rapid sintering method of zirconia ceramic for dentistry comprises the following steps: obtaining a pre-sintered body prepared from zirconia powder with stable yttrium oxide, and obtaining a standard active sintering temperature of the zirconia powder; the pre-sintered body is subjected to final sintering in a preset final sintering stage, the zirconia ceramic is obtained, the preset highest sintering temperature in the preset final sintering stage is higher than the standard active sintering temperature, and the difference value between the preset highest sintering temperature and the standard active sintering temperature ranges from 10 DEG C to 60 DEG C. According to the embodiment of the invention, the preset highest sintering temperature in the preset final sintering stage is set to exceed the standard active sintering temperature by 10-60 DEG C, so that the highest sintering temperature of the final sintering process is improved, the final sintering time of the zirconia ceramic is shortened, the production efficiency of the zirconia ceramic product is improved, and the production cost is reduced. And meanwhile, the material can obtain excellent mechanical properties and transparency within an extremely short time.

The present invention achieves exceptional adhesive strength, and inhibits any decrease in adhesive strength even when a filling material is packed to a greater thickness. Provided is a single-component-type dental adhesive composition that is used in order to bond a photocurable filling material to dentin, the composition containing a polymerizable monomer (A) including an acid monomer (A1), a photopolymerization initiator (B), water (C), a water-soluble organic solvent (D), and a monovalent to tetravalent metal compound (E). The acid monomer (A1) includes a strong acid monomer (a1) and a carboxylic-acid-polymer-based polymerizable monomer (a2). The amount of the monovalent to tetravalent metal compound (E) contained per 1 mol of the strong acid monomer (a1) is 0.02-1 mol in terms of the number of moles of metal ions constituting the monovalent to tetravalent metal compound (E). The amount of the monovalent to tetravalent metal compound (E) contained per 1 g of the carboxylic-acid-polymer-based polymerizable monomer (a2) is 0.0002-0.005 mol. The metal ions constituting component (E) form an aggregate with at least some of the strong acid monomer (a1).　

The invention relates to an enamel repair material and a preparation method thereof, and belongs to the technical field of medical filling materials for tooth defects, the enamel repair material comprises F-HAp, APTES-ZrO2, MPC modified composite resin, 10-MDP, gamma-MPS, a composite initiator, MPC and a dispersant; f-HAp is a fluorine-doped enamel-like hydroxyapatite nanorod, and F-HAp is a fluorine-doped enamel The APTES-ZrO2 is nano zirconium oxide modified by aminopropyl triethoxy silane, and the nano zirconium oxide modified by the aminopropyl triethoxy silane is The MPC modified composite resin is 2-methacryloyloxyethyl phosphorylcholine grafted and modified dimethyl acrylic acid carbamate and glycidyl methacrylate elastomer composite resin; the F-HAp, APTES-ZrO2 and MPC modified composite resin is prepared by adopting a special method, and is compounded with other components according to a certain proportion to obtain the enamel repair material, so that the enamel repair material has good cohesiveness, strength and biocompatibility and excellent leakage resistance, and the use safety and durability are improved.

According to the antibacterial zirconia false tooth porcelain block material and the preparation method thereof, a piezoelectric ceramic material is added into the zirconia false tooth porcelain block material, and the piezoelectric discharge characteristic of the piezoelectric composite material is utilized, that is, in the daily food chewing process of a human body, the piezoelectric ceramic material can be used as a piezoelectric ceramic material; the piezoelectric potential generated by the periodic compression mechanical vibration of the zirconia false tooth material is catalyzed to generate reactive oxygen species (ROS) to kill bacteria, so that the false tooth achieves the bacteriostatic effect in the use process, and the bacteriostatic effect is stable and efficient; the technical problems that an existing antibacterial zirconia false tooth material is high in cost due to the fact that silver ions are used, and the sterilization performance is reduced after the antibacterial zirconia false tooth material is used are effectively solved.

A photocurable composition includes a (meth)acrylic monomer component and a photopolymerization initiator, wherein an adhesive force of a cured product is less than or equal to 1.5 N, and a rupture elongation of the cured product is greater than or equal to 20%.

Polymerizable, radiation-curable compositions are provided and comprise (i) monomers and (ii) at least one further component, wherein the (i) monomers comprise (a) at least one urethane (meth)acrylate that is at least difunctional, (b) at least one monofunctional acrylate having an alicyclic group and / or at least one monofunctional methacrylate having an alicyclic group, and (ii) the at least one further component comprises (c) at least one photoinitiator for the UV and / or visible range or a photoinitiator system for the UV and / or visible range. The compositions are usable for producing, via a rapid prototyping, manufacturing, or tooling process, dental prosthetic parts, orthopaedic instruments, or dental pre-forms that have a flexural strength of greater than or equal to 75 MPa, a modulus of elasticity of greater than or equal to 2600 MPa, and / or a water absorption of less than 45 [μg / mm3].

To provide a dental medical member exhibiting superior adhesive strength, and a method for producing the dental medical member.SOLUTION: A dental medical member comprises a zirconia (Zr) material as a substrate, where the substrate includes an ion implantation region with implanted silicon (Si) or phosphorus (P) ions, and where the ion implantation level within 20 nm from the surface is 2×1012 ions / cm2 or more. A method for producing a dental medical member includes a step of implanting silicon (Si) or phosphorus (P) ions into a substrate composed of a zirconia (Zr) material to form an ion implantation region, where the ion implantation level within 20 nm from the surface is 2×1012 ions / cm2 or more.SELECTED DRAWING: Figure 6