61results about How to "Reduce vomiting" patented technology

The invention provides a novel Exendin variant and the Exendin variant conjugate conjugating polymer thereon, the pharmaceutical composition comprising them and use of them for treating diseases such as reducing blood glucose, treating diabetes, especially Type II diabetes. The invention also provides the use of Exendin conjugate for lowering body weight.

The objective of the invention is to provide a traditional Chinese medicine granule for treating side effects on an alimentary canal after cancer chemotherapy and a preparation method thereof. The invention is characterized in that the granule is prepared from an active component, a binder and pharmaceutically acceptable adjuvant, and the active component is prepared from the traditional Chinese medicines consisting of 600 to 800 g of milkvetch root, 250 to 350 g of dwarf lilyturf tuber, 150 to 250 g of red ginseng, 150 to 250 g of white atractylodes rhizome fried with bran, 150 to 250 g of Poria cocos, 200 to 300 g of licorice, 200 to 300 g of radix scrophulariae, 200 to 300 g of Chinese angelica, 250 to 350 g of dark plum, 250 to 350 g of prepared pinellia tuber, 200 to 300 g of cablin patchouli herb, 200 to 300 g of dried orange peel and 200 to 300 g of curcuma rhizome. The granule is applicable to cancer patients who vomit or retch because of damage of both qi and yin and rising of stomach qi resulting from damage of the spleen and the stomach by anti-radiogenic cancer and chemotherapy drugs, and the granule can mitigate symptoms like no appetite, tiredness, hypodynamia, a red or light red tongue with little fluid and weak pulse.

The invention provides a novel Exendin variant and the Exendin variant conjugate conjugating polymer thereon, the pharmaceutical composition comprising them and use of them for treating diseases such as reducing blood glucose, treating diabetes, especially Type II diabetes. The invention also provides the use of Exendin conjugate for lowering body weight.

The invention provides a method for preparing an enhanced DC-CIK cell induced by traditional Chinese medicines. The method comprises the step of adding extracts of radix astragali and radix codonopsitis into a DC or CIK cell culture fluid or DC-CIK cell culture fluid or DC, CIK and DC-CIK cell culture fluids, wherein the extracts of radix astragali and radix codonopsitis are radix astragali polysaccharide and radix codonopsitis polysaccharide. According to the method disclosed by the invention, the activity and the functions of the DC or CIK cell can be activated, and the specificity of the DC-CIK cell is improved so that the DC-CIK cell can resist tumor in the body for long time; a large amount of DC-CIK cells can be obtained according to the method, and the cell culture time is reduced; the enhanced DC-CIK cells obtained according to the method disclosed by the invention can be used for cell treatment of tumor diseases, and can directly kill tumor cells and adjust the immunity of the body when re-infused into the body.

The invention discloses application of a phosphodiesterase4 (PDE4) inhibitor ZL-n-91 in preparing medicine for treating prostate cancer proliferation and transfer. Animal experiments and cytology experiments of mice are utilized to show that the phosphodiesterase4 inhibitor ZL-n-91 disclosed by the invention can obviously inhibit prostate cancer cell proliferation and transfer, so that the phosphodiesterase4 inhibitor ZL-n-91 is indicated to hopefully become an important target of prostate cancer proliferation and transfer researches, a foundation is provided for preparing medicine for resisting prostate cancer proliferation and transfer, and the phosphodiesterase4 inhibitor ZL-n-91 has a good development and application prospect.

A pet food comprising an aggregate of granules, wherein 60% or more of the granules in the aggregate have a hardness of 2.5 kgw or lower immediately after being soaked in diluted hydrochloric acid (pH 2.5) having a temperature of 20 to 25° C. for 10 minutes.

The invention discloses an effective fraction of Xiao Ban Xia Tang. The effective fraction has physicochemical properties that: the effective fraction is a yellowish-brown extract, has certain moisture absorption and can be dissolved in hot water and ethanol; and the effective fraction mainly contains organic acid components, such as succinic acid, hydroxysuccinic acid, citric acid and linoleic acid. The invention also discloses a preparation method and application of the effective fraction of the Xiao Ban Xia Tang. An organic acid part extracted from the Xiao Ban Xia Tang has obvious pharmacological and pharmacodynamic effects. The effective fraction has an obvious effect of arresting vomiting; and through experimental models of pigeon emesis induced by both bluestone and cisplatin, results indicate that the organic acid part has obvious activity of arresting vomiting and can obviously reduce the vomiting frequency of pigeons; and the effective fraction has an effect of inhibiting gastric emptying of normal mice.

The invention discloses an effective part of a small Pinellia ternate decoction. The effective part has the following physical and chemical properties: the effective part is a yellow oily substance, and the effective part which has certain volatility can be dissolved in hot water and ethanol; and the effective part which mainly contains gingerol and shogaol components concretely contains 40-50% of 6-gingerol and 12-20% of 6-shogaol. The invention also discloses a preparation method and an application of the effective part of the small Pinellia ternate decoction. The fat-soluble effective partextracted from the small Pinellia ternate decoction has the following obvious pharmacological drug effects: 1, the vomiting prevention effect is obvious, results of experiments of pigeon vomiting caused by copper sulfate and a chemotherapeutic cis-platinum as experiment models show that the fat-soluble part has a substantial vomiting prevention activity and can obviously reduce the vomiting frequency of pigeons; and 2, the effective part has a normal mouse stomach evacuation inhibition effect.

The invention discloses a liquid feed bag which comprises a bag body made of a flexible material, wherein a liquid orifice used for allowing liquid to flow in and out of the bag body and an air orifice used for allowing air to flow in and out of the bag body are formed in the bag body; a liquid tube is inserted into the liquid orifice and connected with the bag body in a sealed manner; the tail end of the liquid tube stretches into the bottom of the interior of the bag body; concentrated liquor or dried powder of a corresponding amount is filled in the bag body according to the volume of the bag body and the concentration of the needed solution; the interior of the bag body is vacuumized, and when the preparation needs to be prepared, reverse osmosis water is injected into the bag body through the liquid tube. The invention further provides a displacement liquid preparation system which comprises the liquid feed bag, and a blood circuit, a blood filter, a displacement liquid circuit, a dialysate supply switch circuit and a waste liquid discharging circuit. The invention has the beneficial effects of being automatic in adjustment, high in control precision, wide in usage range, convenient to use, low in cost, stable and reliable.

The present invention provides a dispersible tablet dosage form of doxifluridine, which is characterized by its speedy decentralization and dissolution when being in vitro. Through clinical applications, it is found that compared to common doxifluridine capsules, the clinical curative effect is considerably improved, at the same time the adverse reaction is remarkably reduced and unexpected effects are acquired. In accordance with the present invention, for extensive cancer patients executing chemotherapy by adopting doxifluridine, the pains of chemotherapy are considerably alleviated, the neoplastic chemotherapy effect is improved, and said medicine has prodigious clinical use values; 5-FU is a specific anti-metabolizing medicine during the S period, and the unexpected effects obtained in accordance with the present invention are of good enlightening significance for researching pharmacodynamics features and mechanism of action of doxifluridine. In addition, it is convenient for aged and children to take the medicine in accordance with the present invention, with stable formulation, fast absorption, high bioavailability and few adverse reaction, which can be used as medicine for treating breast carcinoma, cancer of stomach, carcinoma of colon, restocarcinoma, nasopharyngeal carcinoma and the like.

The invention relates to the field of mechanical instruments, in particular to a gravity sham feeding device. The gravity sham feeding device comprises a container, a container cover and a connector located at the bottom of the container. A connector cover is arranged outside the connector and a nipple is further connected to the feeding device. The feeding device is connected with the nipple through the container and gravity feeding is combined with sham feeding. According to the gravity feeding, milk is evenly and slowly dripped into the stomach through the gravity action, the milk gradually flows to the small intestine along with gastrointestinal motility, and therefore abdominal distension and emesis are reduced. Compared with nasal feeding, the gravity feeding has the advantages that the milk amount of a premature infant is increased, the whole stomach and intestine nutrition time can be achieved in advance, complications related to feeding are reduced, weight gain can be facilitated, the time of a hospital stay is shortened, and the work efficiency of a nurse is improved. Sham feeding is conducted at the same time, and therefore the premature infant can be stimulated through non-nutritive sucking so that the vagus can be excited and the gastrointestinal tract G cells can be stimulated to conduct gastrin secretion; meanwhile, the sucking ability of the infant can be trained and a certain pacifying function can be achieved.

The invention discloses a double-cavity balance fluid supply system with fluid preparation functions for purifying blood. The double-cavity balance fluid supply system comprises a blood circuit, a blood filter, a substitution fluid circuit, a dialysis fluid supply switching circuit and a waste fluid drain circuit. A first inlet of the blood filter is communicated with an outlet of the dialysis fluid supply switching circuit and the arteries of a human body via the blood circuit, and a first outlet of the blood filter is communicated with the veins of the human body via the blood circuit; a second inlet of the blood filter is communicated with an outlet of the substitution fluid circuit via the dialysis fluid supply switching circuit, and fluid can be outwardly drained from a second outlet of the blood filter via the dialysis fluid supply switching circuit and the waste fluid drain circuit; the dialysis fluid supply switching circuit comprises at least two supply circuits, and the various supply circuits are alternately communicated with the second inlet of the blood filter or closed to the second inlet of the blood filter and can be alternately communicated with the second outlet of the blood filter or closed to the second outlet of the blood filter, so that continuous supply structures can be switched over. The double-cavity balance fluid supply system has the advantages of automatic adjustment, high control precision, convenience in use, stability and reliability.

The invention discloses a solute clearing monitoring system of blood purification equipment. The solute clearing monitoring system comprises a blood loop, a blood filter, a displacement liquid loop, a dialysate supply switching loop and a waste liquid discharging loop, wherein a first electric conducting detection device is connected in series between a second inlet of the blood filter and the dialysate supply switching loop; a second electric conducting detection device is connected in series between a second outlet of the blood filter and the dialysate supply switching loop. The invention also provides a solute clearing monitoring method of the blood purification equipment; the method comprises the following steps of (1) respectively detecting the electrical conductivity of the second inlet and the second outlet of the blood filter through the first electric conducting detection device and the second electric conducting detection device every other set time; (2) obtaining the clearing rate of dialyzate ions according to an expression; (3) calculating a urea clearing kinetic model. The system and the method have the advantages that the monitoring on the concentration of the cleared solute in real time can be realized; the concentration of concentrated electrolyte A and B does not need to be changed in the real-time monitoring process.

This invention relates to a 24 hour extended release dosage formulation and unit dosage form thereof of venlafaxine hydrochloride, and antidepressant, which provides better control of blood plasma levels than conventional tablet formulations which must be administered two or more times a day and further provides a lower incidence of nausea and vomiting than the conventional tablets. In its primary aspect, this invention provides an improved core of the extended release spheroids comprised of venlafaxine hydrochloride and microcrystalline cellulose, that is, without the addition of hydroxypropylmethylcellulose.

The invention discloses the technical field of edible oil and specifically relates to compound edible oil for pregnant women and a preparation method thereof. Raw materials of the compound edible oilcomprise: camellia seed oil, refined sesame oil, walnut oil, purple perilla seed oil and a DHA emulsion. The camellia seed oil and purple perilla seed oil have a good regulating effect on the heart and cerebral vessels, digestion, reproduction, neuroendocrine and immune system of pregnant women, and effectively reduce the occurrence of hypertensive symptoms during pregnancy. Refined sesame oil isrich in vitamin E, and has a flavor-enhancing effect. Vomiting and loss of appetite are prone to occur for pregnant women in the early stage of pregnancy. Refined sesame oil makes the compound edibleoil for pregnant women taste delicious so as to effectively improve the appetite of pregnant women. Walnut oil and the DHA emulsion promote the development of fetal brain. The DHA emulsion is preparedfrom DHA algae oil as a raw material. With the addition of the emulsifier, stability of DHA algae oil is increased so as to increase stability of the compound edible oil for pregnant women and make the compound edible oil to be easily stored.

The invention relates to dendrobii officinalis caulis wine capable of protecting intestines and stomach and nourishing faces, and belongs to the technical field of dendrobium wine. The dendrobii officinalis caulis wine is prepared from the following raw materials in parts by weight: 9-15 parts of base wine and 0.2-1.5 parts of dendrobii officinalis caulis extract. The extraction method of the dendrobii officinalis caulis extract comprises the following steps: A1, pretreatment; A2, drying; A3, extraction; and A4, concentration. The invention also relates to a preparation method of the dendrobiiofficinalis caulis wine capable of protecting intestines and stomach and nourishing faces. The preparation method comprises the following steps: S1, cooking; S2, fermentation; S3, secondary fermentation; and S4, filtering. The method can improve nutritional ingredients of the dendrobii officinalis caulis wine, and the wine achieves the effects of tonifying the spleen, nourishing the stomach and enhancing immunity.

A disposable acupressure strip providing 72 hours of nausea and vomiting relief for surgery and cancer treating patients includes a raised portion of a contact button extending from a film substrate through a cutout positioned over the P6 pericardium acupressure point on a user's wrist and secured there by a medical grade surgical adhesive tape.

The invention provides a natural efficient anti-hair-loss hair restorer. A formula of the natural efficient anti-hair-loss hair restorer comprises cannabidiol crude oil, Morocco nut oil, frankincenseoil, tea tree oil, castor oil, bergamot oil and cannabis oil. Raw materials are weighed according to the formula, the raw materials are put into a mixing kettle to be stirred for 10-15 minutes at thetemperature of 35-39 DEG C to enable the raw materials to be in a homogenate state, still standing is conducted for two hours to obtain the natural efficient anti-hair-loss hair restorer, and bottlingis conducted by using a rubber head dropper tool. The natural efficient anti-hair-loss hair restorer is prepared by taking the cannabidiol crude oil as the main raw material, cannabidiol acts on receptors such as the CB1 receptor, the TRPV1 receptor and the 5-HT1A receptor in a human body, thus the activity of 5-alpha reductase is inhibited advantageously, androgen can be generated after the 5-alpha reductase is controlled to react with and testosterone in the human body, and thus the aim of treating alopecia is fulfilled by reducing the androgen level.

The invention provides application of polaprezinc in preparation of a medicine for treating or alleviating alimentary tract complications and irritable bowel syndromes caused by chemoradiotherapy. By the aid of the polaprezincr, rising of emesis-related neurotransmitters incluiding 5-hydroxy tryptamine and NF-kB in blood and brain tissues, which is caused by the chemoradiotherapy, can be lowered, stimulations and hurts to the alimentary tract from the chemoradiotherapy can be reduced, and related symptoms of 5-hydroxy tryptamine related irritable bowel syndromes can be alleviated; proved by clinical tests, the polaprezincr is capable of alleviating symptoms of emesis and alimentary injuries of a patient effectively and is remarkably effective in treatment of 5-hydroxy tryptamine related irritable bowel syndromes.

Sublingual immunotherapy (SLIT) with reduced oral itchiness is disclosed. The improved sublingual immunotherapy combines a monotonically increasing dose of allergen, along with a constant dose of mast cell stabilizer, thereby substantially avoiding the oral itchiness and other uncomfortable adverse reactions typically experienced with SLIT, which can improve patient compliance. An antihistamine and / or a leukotriene inhibitor can also be added along with the mast cell stabilizer. Multi-layer and / or coated tablets, and flexible paired ampoules with special features to advantageously time the dose of the allergen relative to the dose of the mast cell stabilizer, have been provided to effectively administer the improved sublingual immunotherapy in a highly convenient manner. Methods, preparations, and apparatuses for administration of SLIT, apparatus for sequentially dispensing, methods for producing a sequence of allergen doses with reduced adverse reactions, methods for producing a stock solution for dilution, and methods for producing cooperative pre-filled vials are also disclosed.

A Chinese medicine for treating esophagus cancer is prepared from compound aspirin, atropine, luminal, and 19 Chinese medicinal materials including curcuma root, red sage root, peach kernal, Chinese angelica root, etc through decocting the Chinese-medicinal materials, comcentrating, and adding said powdered Western medicines.

Provided is pet food which contains refined cellulose and has a moisture content of 6% to 15% by mass, in which an average grain size of the refined cellulose is 50 μm or greater, and 60% or more of food granules in the entire food granules constituting the pet food have a hardness of 2.5 kgw or less immediately after being immersed in dilute hydrochloric acid (pH of 2.5) at 25° C. for 10 minutes.

I study Neijing and Compendium of Materia Medica for many years, screen out natural medicinal materials which grow in China, and develop a special-acting drug-a traditional Chinese medicine anticanceragent which can resist malignant tumors in the middle and advanced stages. The agent is non-toxic, and has special effects on lung, stomach, liver, kidney, heart disease, esophagus, breast, thyroid,cervix, colorectal, leukemia and the like, and cure rate is much higher than 62%. For the human immunodeficiency virus, the agent can reduce a HIV viral load. The mechanism of the agent is to block anenergy source of cancer cells, resist the growth of tumor angiogenesis, enhance immune functions, (devour and destroy heterogeneity in blood), induce tumor cell apoptosis and block oncogene mutationand transcription. If the traditional Chinese medicine anticancer agent is taken, pain, nausea and vomiting are soon alleviated and disappeared. Diet is increased, sleep is improved, physical strengthis increased, and the development of the cancer cells is obviously controlled. A tumor block is softened, shrunk and disappeared. After two to three courses of treatment (three months after one course of the treatment), B-ultrasound or CT are used for re-examination of a patent with fast curative effect, a primary lesion disappears, no metastasis and recurrence occurs, and the patient has good health.

The invention relates to a medicine for treating adverse reaction of digestive tract in tumor radiotherapy and chemotherapy and preparation method thereof. According to the medicine disclosed by the invention, cyclo-(leucine-tyrosine) and isoprenone are used as active components for treating the adverse reaction of the digestive tract in the tumor radiotherapy and chemotherapy, so that synergistic interaction of the two active components can be exerted, retching latency period of a patient received tumor radiotherapy and chemotherapy can be prolonged, and retching and vomiting times can be reduced.

The invention discloses an application of a traditional Chinese medicine composition in preparation of a medicine for treating dementia. The traditional Chinese medicine composition is composed of 11traditional Chinese medicines such as radix astragali, radix ginseng and radix salviae miltiorrhizae. The research finds that on the basis of Western medicine routine treatment, the medicine is added,the curative effect of treating the senile dementia and the improvement of the life quality of patients are obviously superior to those of pure western medicine treatment, and it is fully proved thatthe medicine has a remarkable clinical curative effect on the dementia caused by various reasons.

The invention relates to a traditional Chinese medicine capable of treating cervical and spinal disc protrusion and / or rheumatism bone diseases. The traditional Chinese medicine contains the following components in parts by weight: 20-50 parts of processed semen strychni, 5-10 parts of frankincense, 5-10 parts of myrrh, 5-10 parts of cortex eucommiae, 5-10 parts of rhizoma curcumae longae, 5-10 parts of radix cyathulae, 5-10 parts of liquorice, 5-10 parts of herba ephedrae, 5-10 parts of ground beeltle, 5-10 parts of rhizoma atractylodis, 5-10 parts of bombyx batryticatus, 2-8 parts of radix angelicae pubescentis, 2-8 parts of herba taxilli, 2-8 parts of rhizome chuanxiong, 2-8 parts of flos carthami, 2-8 parts of pawpaws and 2-8 parts of dipsacus asperoides. The traditional Chinese medicine disclosed by the invention has the efficacies of enriching and activating blood, dredging collaterals, dispelling wind, eliminating dampness, expelling coldness, removing stasis, promoting tissue regeneration, promoting the circulation of vital energy, arresting convulsion, relieving pain, removing bone spurs, tonifying kidney, strengthening tendons and bones and treating both symptoms and root causes, can take effect rapidly, is definite in treatment effect, short in recovery period and unlikely to relapse and has no toxic and side effects.

The invention relates to a catheter device and a method thereof for waking up the anesthesia in a brain functional region surgery, comprising a tracheal catheter, an opening is formed on the top of the outer end of the tracheal catheter which is inserted to the esophagus direction, the top part of the inner end is closed, an esophagus closed cuff is arranged in the vicinity of the top part of theinner end, a pharyngeal cavity closed cuff is further arranged on the tracheal catheter; a vent hole is arranged at the part of the tracheal catheter between the esophagus closed cuff and the pharyngeal cavity closed cuff for leading an air duct to be communicated with and a glottis of a trachea; the esophagus closed cuff and the pharyngeal cavity closed cuff are respectively connected with a ventpipe. The catheter device is provided with the esophagus closed cuff and the pharyngeal cavity closed cuff on the tracheal catheter and is provided with the vent hole between the esophagus closed cuff and the pharyngeal cavity closed cuff, so the usage of the catheter device of the invention for carrying out the waking-up of the anesthesia can not only meet the requirements on the precise positioning of the function region, but can also be safe and convenient, and the catheter does not need to be inserted and drawn repeatedly, thus eliminating the risks of excessive injuries of a patient, being able to resect a tumor to the maximum extent and protecting the normal brain tissues of the brain functional region to the utmost extent.

The invention belongs to the field of medicines or health products, and particularly relates to a composition for assisting conditioning of tumor radiotherapy and chemotherapy patients and a preparation method thereof. The technical problem solved by the invention is to provide a brand-new composition for replenishing uprightness of a body and enhancing physique, especially for the assisting conditioning of the tumor chemotherapy and the radiotherapy patients, and a role of auxiliary protection against radiation hazards. The composition of the invention adopts cordyceps, reishi shell-broken spore powder, radix angelicae sinensis, radix astragali, cortex cinnamomi and radix glycyrrhizae as raw material medicines, and the weight ratios are as follows: 1 to 8 parts of cordyceps, 5 to 30 partsof reishi shell-broken spore powder, 3 to 25 parts of radix angelicae sinensis, 10 to 80 parts of radix astragali, 3 to 25 parts of cortex cinnamomi and 10 to 60 parts of radix glycyrrhizae. Comparedwith similar products on the market, the composition for the assisting conditioning of the tumor radiotherapy and the chemotherapy patients has the advantages of a clear effect, a stable curative effect and being controllable, and provides public with a brand-new choice.

The invention discloses lysine hydrochloride and zinc gluconate tablets. The lysine hydrochloride and zinc gluconate tablets are prepared from lysine hydrochloride, zinc gluconate, bulbil of common yam, hawthorn fruit and radix astragali. By adding effective constituents of bulbil of common yam, hawthorn fruit and radix astragali based on an existing formula of lysine hydrochloride and zinc gluconate tablets, the compound lysine hydrochloride and zinc gluconate tablets combining traditional Chinese medicine with western medicine are prepared. The prepared lysine hydrochloride and zinc gluconate tablets can well solve the problems of growth retardation, malnutrition and anorexia of children and teenagers due to lack of lysine and zinc, can also greatly relieve gastrointestinal tract irritation and reduce adverse drug reaction, and can reduce side effects such as stomach discomfort, nausea, vomiting and constipation.