69 results about "Shogaol" patented technology

The invention relates to the field of natural medicines, in particular to application of 6-shogaol to treating cervical cancer, leukemia and breast cancer. A pharmacological activity research of the 6-chogaol discovers that even if the 6-shogol displays the curative activity to a plurality of tumors, the activity differences of different tumors are great, the 6-shogaol has best treating effects to cervical cancer, leukemia and breast cancer in massive tumor inhabitant experiments, and the treating effects to the three cancers are remarkably better than that of other cancers.

It is an object of the invention to discover a substance that effectively increases the production of adrenomedullin, as well as to provide an adrenomedullin production-enhancing agent utilizing this substance. The adrenomedullin production-enhancing agent is characterized by inclusion of a ginsenoside, a sanshool, and / or a shogaol as active ingredients.

The compound represented by the following formula (1):wherein A, B, R1, R2, R3 and Z are as defined in the specification is analogous to shogaol and gingerol useful in the fields of foods, medicines, quasi-drugs, cosmetics, etc., and more highly active in tyrosinase activity inhibition, etc. than shogaol and gingerol.

In accordance with the invention, an industrial process for producing shogaols useful in the fields of for example foods, flavor, pharmaceutical products, qui-pharmaceutical products and cosmetics can be provided. The invention relates to novel intermediates represented by the following general formula and a process for producing shogaols from the intermediates. In accordance with the invention, shogaols can readily be produced, of which mass production has been difficult because shogaols have been produced only by the extraction process from a natural ginger.Intermediates;(in the formula (1), R1 represents hydrogen atom or methyl group; R2 represents optionally branched alkyl group with one to 18 carbon atoms; R3 and R4 each independently represents hydrogen atom, a lower alkyl group or a protective group of the phenolic hydroxyl group; A represents an alkylene group with one to 4 carbon atoms; and X represents benzenesulfonyl group or toluenesulfonyl group.)

The present invention provides a pharmaceutical composition for preventing or treating learning disorders, memory disorders, Parkinson's disease, or ischemic cerebrovascular disease, which comprises a ginger extract or shogaol; and a pharmaceutically acceptable carrier. And also, the present invention provides a food composition for improving learning disorders or memory disorders or alleviating the symptoms of learning disorders or memory disorders which comprises a ginger extract or shogaol as an active ingredient, or a food composition for improving learning or memory which comprises a ginger extract or shogaol as an active ingredient.

The invention discloses a marine antifouling nano paint, which is prepared from the following raw materials: epoxy phenolic resin, titanium dioxide, a nano biological antifouling agent, filler, an acetic acid, and glyceryl tristearate. Capsaicin in the nano-scale biological antifouling agent has a good approach-avoidance effect on marine organisms; tannic acid has an adhesion inhibition effect on barnacle and also has a paralysis function on the beetle; shogaol has strong ability of preventing adhesive ability of mussel. P-cinnamic acid sulfate has a strong adhesion inhibition effect on marine bacteria and barnacle, homarine can prevent adhesion of marine benthic diatom and barnacle, and diterpenes formamide has an effect of inhibiting the barnacle and shellfish larvae. The paint disclosed by the invention comprises a nano-scale pure natural biological antifouling agent, has the approach-avoidance effect on marine organisms, and destroys the adhesive ability of the marine organisms, so as to achieve the target of preventing and treating pollution. The marine antifouling nano paint does not generate any deleterious effect on the marine environment, is free of an injury to the marine organisms, and is purely natural and harmless.