13 results about "Zingerone" patented technology

The invention relates to the technical field of cosmetics, in particular to a sensitive skin care composition for soothing nerves and a preparation method thereof. According to the sensitive skin care composition capable of soothing the nerves, provided by the invention, the acetyl zingerone clathrate compound, the strawberry fruit extract and the 4-tert-butyl cyclohexanol are compounded, and through the dual-channel synergistic effect of transient inhibition of neural signals and long-acting repair of a cell microenvironment, the synergy of immediate soothing and long-term barrier repair is realized; the vicious circle of sensitive skin is effectively blocked.

The present invention relates to the field involved in the production of phenylbutanone or phenylbutanone derivative compounds, such as frambinone or zingerone, and in particular strains genetically modified to express a benzalacetone reductase.

The invention relates to a preparation method of boiled wine, which is characterized in that red wine is used as base wine, auxiliary materials such as dried orange peel, white pepper, dried shredded ginger, haw slices and xylitol are added, and the boiling is completed through a multi-step preparation process. The method comprises the steps of pre-frying, braising, pre-cooking, high-pressure braising, secondary cooking, low-temperature seasoning cooking and the like, and it is ensured that aromatic substances in the auxiliary materials are fully released. Compared with a traditional boiling technology, coumarin and citrus aldehyde in the dried orange peel and gingerol in the dried ginger shreds can be reserved in the stir-frying and braising processes, so that part of piperine in the white pepper is volatilized, and the spicy feeling is reduced; high-pressure braising and natural cooling prevent aromatic substances from volatilizing along with steam. In addition, secondary cooking can promote the conversion of gingerol to zingerone, so that the cooked grape wine is more sweet and warm in mouth feel, and the quality and flavor of the finished product are improved.

The invention relates to an agent containing zingerone, an active plant compound derived from ginger that is easy to use, non-toxic, antioxidant, and anti-apoptotic, for the treatment of diabetes-related male reproductive damage.

The invention belongs to the technical field of biological medicine, and provides a zingiberone-loaded self-assembled nano-drug, a soluble microneedle patch as well as a preparation method and application thereof, and the zingiberone-loaded self-assembled nano-drug comprises zingiberone, indocyanine green and a polymer mPEG-PLA in a mass ratio of (1.5-5): (0.35-1.4): (10-20). The invention also provides a preparation method of the zingiberone-loaded self-assembled nano-drug. The invention further provides a soluble microneedle patch, the soluble microneedle patch comprises the zingiberone-carrying self-assembled nano-drug, and the soluble microneedle patch comprises a patch substrate and a needle head arranged on the surface of the patch substrate; the needle head is prepared from a ball-carrying zingerone self-assembled nano-drug and a soluble matrix material. The zingiberone-loaded self-assembled nano-drug provided by the invention has an anti-tumor effect, can be used for treating melanoma, and improves the solubility and bioavailability of zingiberone.

The present disclosure generally relates to ketone compounds, such as zingerone, and their use for enhancing the perception of alcohol (ethanol) in food, beverages, and other comestible compositions. In certain aspects, the disclosure provides the use of such ketone compounds to enhance an alcoholic (ethanolic) flavor of a beverage, for example, a low-alcohol or zero-alcohol beverage. In certain other aspects, the disclosure provides low-alcohol or zero-alcohol beverages containing such ketone compounds.

The present invention relates to the field of cosmetic products, and is notably directed towards proposing the cosmetic use of i) at least one compound of formula (I) With R1, R2, R3, R4, et R5, and A as defined in the description as a masking agent and / or as an inhibitor of the odour ii) of organic UV-A and / or UV-B screening agent(s), and also to compositions comprising one or more UV-A and / or UV-B screening agent(s).

Disclosed herein is a frambinone methacrylate (FMA) or raspberry ketone methacrylate (RKMA) monomer having the following structure:anda zingerone methacrylate (ZMA) having the following structureAlso disclosed are homopolymers and co-polymers utilizing same monomer. Also disclosed is a class of methacrylate monomers comprising a bio-based moiety and a reactive ketone moiety. Also disclosed are paint compositions made with a copolymer including FMA and / or ZMA.

The invention discloses an anti-tumor composition and application thereof. The active ingredients of the composition are sunitinib with a treatment effective dose and zingiberenone A for enhancing the treatment effect of the sunitinib. The concentration ratio of zingiberenone A to sunitinib is 1: (0.5-2.5). According to the anti-tumor composition provided by the invention, the zingiberenone A and sunitinib are combined for use, so that the drug sensitivity of tumors can be improved, a synergistic effect on inhibiting the multiplication capacity and migration capacity of human kidney cancer cells 786-O is achieved, and a new strategy is provided for treating renal cell carcinoma.

The invention relates to the field of gene engineering, and discloses a recombinant strain for producing zingiberone, a construction method and application of the recombinant strain, and a method for producing zingiberone through fermentation. The recombinant strain is obtained by using yarrowia lipolytica as an original strain through genetic engineering modification, and compared with the original strain, a polygene co-expression plasmid of P450 hydroxylase-zingiberone synthase-P450 reductase is introduced into the recombinant strain. The recombinant strain provided by the invention has the advantages of high fermentation yield of zingiberenone, easiness in extraction of fermentation products and the like, heterologous production of zingiberenone is realized, the catalytic efficiency from alpha-humulene to zingiberenone is improved, the yield of zingiberenone is remarkably improved, and the production process is simple and easy to industrialize.

The application discloses application of a novel nano preparation containing zingerone A in preparation of an antitumor drug, and the nano preparation comprises aminated dendritic mesoporous silica and zingerone A loaded on the aminated dendritic mesoporous silica. The application adopts the aminated dendritic mesoporous silica to load the zingerone A, and a novel nano preparation containing zingerone A with high drug loading, high encapsulation rate and high biocompatibility is prepared. The preparation has low cytotoxicity, can be quickly taken up by tumor cells, significantly enhances the ability of the zingerone A to remove tumor cells, effectively inhibits the proliferation of tumors in vivo, and has a treatment effect superior to that of a commonly used clinical antitumor drug, namely, dabrafenib, and has a wide application prospect.

Disclosed are methods of preparing zingerone from ginger, as well as compositions obtained using these methods and methods of using these compositions. Beneficial compositions and methods of utilizing these compositions are disclosed.

Described herein are compositions and formulations for the treatment of acne, hyperpigmentation, wrinkles, and combinations thereof. The compositions comprise active agents in amounts of from about 0.1-20% based on the total weight of the composition, and an active agent comprising at least one hyperpigmentation agent in an amount of 15 weight % or less. In some embodiments, the composition comprises acetyl zingerone, azelaic acid, bakuchiol, and licorice extract.