Medical application of natural product 6-shogaol in enhancing chemosensitivity of pancreatic cancer on gemcitabine and compound drug composite of natural product 6-shogaol

A technology of gemcitabine and shogaol, applied in the field of natural medicine
CN103263433AInactive Publication Date: 2013-08-28CHINA PHARM UNIV
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Patent Information

Authority / Receiving Office
CN Β· China
Current Assignee / Owner
CHINA PHARM UNIV
Publication Date
2013-08-28
Estimated Expiration
Not applicable Β· inactive patent

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Abstract

The invention relates to the field of natural drugs, and discloses medical application of natural product 6-shogaol in enhancing the chemosensitivity of pancreatic cancer on gemcitabine and a compound drug composite of the natural product 6-shogaol. According to the invention, low-dose gemcitabine can generate biological effect under high dose through the combined administration of the 6-shogaol and the gemcitabine, so that the clinical usage amount of the gemcitabine can be greatly reduced, the toxic side effect can be reduced, the clinical treatment safety index can be enhanced, and good clinical application development prospect is achieved.
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Description

technical field

[0001] The invention relates to the field of natural medicines, and discloses a medical application of a natural product 6-shogaol that can enhance the chemosensitivity of pancreatic cancer to gemcitabine and a compound pharmaceutical composition thereof. Background technique

[0002] Pancreatic cancer is a malignant tumor of the digestive tract with hidden clinical manifestations, rapid development, and poor prognosis. Its early diagnosis is difficult and treatment methods are limited, so the mortality rate is high. In western countries, the death rate of pancreatic cancer ranks fourth; in my country, pancreatic cancer is also one of the three major digestive tract malignancies. Traditional treatments for pancreatic cancer mainly include surgery, radiotherapy, and chemotherapy. So far, surgery is still the most effective treatment for pancreatic cancer, but pancreatic cancer lacks obvious symptoms in the early stage, and most cases have lost the chance of r...

Claims

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