Quality control method for dried ginger

A quality control method, the technology of dried ginger, applied in the direction of measuring devices, instruments, scientific instruments, etc., can solve the problems of evaluating the quality of dried ginger medicinal materials, and achieve the effect of ensuring clinical curative effect and good accuracy

Inactive Publication Date: 2019-02-01
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Abstract
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AI Technical Summary

Problems solved by technology

At present, the quality control methods of dried ginger medicinal materials reported in the literature mainly use gingerol chemical components as the main evaluation indicators, while the 2015 edition of "Chinese Pharmacopoeia" only includes 6-gingerol as the content determination of dried ginger medicinal materials, which is difficult to comprehensively and accurately Objectively used to evaluate the quality of dried ginger
At present, there is no report on the comprehensive and effective control of dried ginger medicinal materials with a multi-index determination method using gingerols and volatile oil active components and fingerprints as quality control indicators.

Method used

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  • Quality control method for dried ginger
  • Quality control method for dried ginger

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Embodiment 1

[0038] 1. a quality control method of dried ginger, which may further comprise the steps:

[0039] (1) Preparation of test solution

[0040]Take about 0.5 g of dried ginger medicinal materials (see Table 1) powder (passed through a No. 3 sieve) from different origins and different batches, weigh them accurately, place them in conical flasks with stoppers, and add methanol with a volume concentration of 75% precisely. 20ml, packed tightly, weighed, ultrasonically treated (power 1000W, frequency 40kHz) for 40min, taken out, allowed to cool, weighed again, supplemented with 75% methanol to make up the lost weight, the extract was centrifuged at 13000rpm for 10min, placed on The supernatant was passed through a 0.45 μm membrane filter, and the filtrate was taken to obtain the test solution.

[0041] (2) Preparation of reference substance solution

[0042] Accurately weigh the appropriate amount of 6-gingerol, 8-gingerol, 6-shogaol, 10-gingerol, α-curcumene and (E)-β-farnesene re...

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Abstract

The invention discloses a quality control method for dried ginger. The method comprises the following steps of: determining the content of 4 ginger phenolic chemical components including 6-gingerol, 8-gingerol, 6-shogaol and 10 gingerol, and 2 volatile oil chemical components including alpha-curcumene and (E)-beta-farnesene in the dried ginger medicinal materials by adopting an HPLC-PDA method; and taking the total amount of the ginger phenolic components, the total amount of the volatile oil components, or the total amount of the ginger phenolic components and the volatile oil components as an evaluation index, which is used for formulating a standard for evaluating the quality of the dried ginger medicinal material and controlling the quality. The method is capable of comprehensively, objectively and effectively evaluating the quality of the dried ginger medicinal material by simultaneously detecting two types of the active ingredients of the dried ginger medicinal material and analyzing the fingerprint spectrum and comparing with a single analysis of one or a class of chemical components, and is used for the quality control thereof, and the method is simple and convenient to operate, good in stability and easy to be popularized.

Description

technical field [0001] The invention relates to a quality control method of Chinese medicinal materials, in particular to a quality control method of dried ginger. Background technique [0002] Dried ginger is the dried rhizome of Zingiber offcinale Rosc., which is commonly used clinically to treat cold pain in the abdomen, vomiting and diarrhea, cold extremities and weak pulse, cold drink and cough. The efficacy of Feihuayin. At the same time, dried ginger is also a commonly used condiment. Modern research shows that dried ginger mainly contains volatile oil, gingerols and diphenylheptane compounds, among which gingerols have anti-inflammatory, anti-oxidation, anti-tumor, liver-protecting and choleretic effects and inhibit the central nervous system, and volatile oil has Anti-hypoxia and improving blood circulation are the main material basis for the traditional efficacy of dried ginger. At present, the quality control methods of dried ginger medicinal materials reported...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N30/02G01N30/06G01N30/74G01N30/54
CPCG01N30/02G01N30/06G01N30/54G01N30/74G01N2030/027G01N2030/062
Inventor 严辉李鹏辉郭盛包贝华彭国平黄胜良汪国强
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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