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66results about How to "Restore immune function" patented technology

Chinese medicinal extract for eliminating face red blood streaks and preparation method and application thereof

The invention discloses a Chinese medicinal extract for eliminating face red blood streaks and a preparation method and application thereof. The Chinese medicinal extract is extracted from a Chinese medicinal composition which consists of rhubarb, pagoda tree flower bud, astragalus and matricaria chamomilla according to the weight part ratio (30-50):(15-25):(15-25):(5-15). The preparation method comprises the following steps of: smashing the rhubarb, pagoda tree flower bud, astragalus and matricaria chamomilla in the ratio; adding propylene glycol serving as an extracting agent for soaking; performing ultrasonic extraction; cooling; filtering and centrifuging; and performing suction filtration, and extracting supernate to obtain the Chinese medicinal extract. The extraction and separationmethod of the Chinese medicinal extract provided by the invention is simple and convenient, the obtained product has high purity, and the product quality is improved greatly. The used Chinese medicinal composition has the effects of reducing the blood vessel permeability, restoring microcirculation, regulating the immunologic function, promoting skin metabolism, increasing collagen and elastin, and the like, so that the extract of the Chinese medicinal composition can be taken as an additive for eliminating face red blood streaks.
Owner:BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY

Anti-African swine fever virus and anti-CD double-target pig-derived antibody, preparing method and application

PendingCN109734810ASolve the problem of mass deathAvoid damageBiocideHybrid immunoglobulinsAntigenInfected cell
The invention relates to the technical field of biological medicine, in particular to an anti-African swine fever virus and anti-CD double-target pig-derived antibody, a preparing method and application. The prepared anti-African swine fever virus and anti-CD pig-derived double-target compound antibody has two antigen combination sites which are combined with African swine fever viruses and immunecells respectively to generate the bridging effect and realize the two major functions; on one hand, the antigen proteins which cause immunosuppression and immune escape are inactivated, the immunosuppression and immune escape are eliminated, and the African swine fever viruses entering a body are killed; on the other hand, the functions of T cells are activated, the immune system is restored, the cell-mediated immunity is started, and virus expansion is prevented; meanwhile, infected cells are split and dissolved, phagocytes are activated to clear away the viruses and the infected cells, andthe aim of preventing and treating the African swine fever viruses is achieved. By means of the compound antibody, a biological medicine and a biological safety feed additive which eliminate the infection of the African swine fever viruses and prevent and treat the African swine fever can be prepared.
Owner:SHENZHEN JASON INTELLIGENT BIOTECH CO LIMLTED PRC

Skin barrier repairing composition and preparation method thereof

The present invention discloses a skin barrier repairing composition and a preparation method thereof. A formula of the skin barrier repairing composition comprises a water phase humectant, an oil phase emulsifier, an active substance, and an organic synthesis intermediate. The oil phase emulsifier comprises the following ingredients in parts by weight: 6-9% of shea butter, 1-6% of crambe abyssinica seed oil, 3-6% of cocoa-caprylate / decanoate, 0.5-4% of limnanthes alba seed oil, 2-10% of isostearyl alcohol isostearate, 1-6% of C12-20 alkyl glucoside and 1-6% of C14-22 alcohol. The preparationmethod comprises the following steps: step one, selecting materials; step two, producing the oil phase emulsifier; step three, producing the water phase humectant; step four, adding the active substance for emulsification; step five, adding the organic synthesis intermediate; and step six, conducting unloading and packaging. The skin barrier repairing composition can maintain skin's normal moisturizing functions, at the same time, the effective soothing ingredients can enhance thickness of epidermal layers and strengthen skin barrier functions, and thus the skin barrier repairing composition strengthens skin's physiological defense system, accelerates skin's metabolism, helps to restore normal immune functions of the epidermal layers and prevents and alleviates couperose skin.
Owner:武汉洛园生物科技有限公司

Natural drug for treating human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS)

InactiveCN102895399AObvious advantageGood effectAntiviralsPlant ingredientsCentipedeClerodendrum cyrtophyllum
The invention discloses an all-natural drug for treating a human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) and a preparation method for the all-natural drug. The all-natural drug is a compound preparation prepared through extracting effective active components from marine organisms and various animal and vegetable medicinal materials. The formulation of the all-natural drug comprises the following components in weight percentage: 10 percent of American ginseng, 10 percent of Astragalus mongholicus, 10 percent of Angelica sinensis, 10 percent of Salvia miltiorrhiza, 10 percent of radix rehmanniae, 5 percent of rheum officinale, 7 percent of goldthread root, 7 percent of Clerodendrum cyrtophyllum, 8 percent of zaocys dhumnade, 8 percent of Gekko japonicus, 7 percent of Chinese Polyphaga, 1 percent of centipede, 1 percent of sea dragon, 1 percent of sea horse and the balance marine algae. On the basis of the new theory of ZhengXue medicine originated by the first applicant of the invention, the formulation of the all-natural drug disclosed by the invention is improved through trial and error. Through pharmacological study and clinical use, the curative effect of the all-natural drug is remarkable. The all-natural drug not only can be used for effectively restraining HIV replication but also can be used for reconstructing an immune system, correcting immunodeficiency and recovering an immunologic function, and host cells infected by the HIV are effectively targeted, so that the viral load is greatly lowered to reach a level that the HIV cannot be checked out, and moreover, the viral load does return after drug withdrawal. The body function can be recovered, and the syndrome can be eliminated. Toxic and side effects do not exist. AIDS patients can be totally recovered.
Owner:莫以贤 +1

Traditional Chinese medicine pill used for treating postpartum thyroiditis and preparation method

The invention discloses a traditional Chinese medicine pill used for treating postpartum thyroiditis and a preparation method, and belongs to the field of traditional Chinese medicine. The traditional Chinese medicine pill is prepared from, by weight, 65-80 parts of radix ophiopogonis, 61-75 parts of Chinese yam, 56-72 parts of adenophora stricta, 53-68 parts of Polygonatum sibiricum Delar., 50-65 parts of jujube, 48-62 parts of dried radix rehmanniae, 45-60 parts of fructus lycii, 42-56 parts of white paeony roots, 40-52 parts of poria cocos, 37-50 parts of radix angelica sinensis, 34-47 parts of atractylodes macrocephala, 32-45 parts of platycodon grandiflorum, 30-42 parts of glossy privet fruit, 8-40 parts of cornus pulp, 26-37 parts of radix codonopsis, 23-35 parts of semen cuscutae, 20-33 parts of radix astragali, 16-30 parts of dendrobium, 14-25 parts of coix seeds, 12-23 parts of caulis bambusae in taenian, 9-20 parts of radix glycyrrhizae, 6-15 parts of oriental stephania roots, 4-10 parts of picrorhiza and 1-5 parts of prunella vulgaris. Medicinal materials selected for the traditional Chinese medicine pill conform to the monarch, minister, assistant and guide principle, the traditional Chinese medicine pill can clear fire, nourish yin, enrich blood and tonify qi and is good in absorption effect, remarkable in treatment effect and free of toxic and side effects and clinical adverse reactions, and the clinical verification shows that the cure rate of the traditional Chinese medicine pill for postpartum thyroiditis is high.
Owner:夏修菲

Microemulsion gel of anti-human papillomavirus(HPV) plant extract and preparation method and application of microemulsion gel

ActiveCN113244357ASolve the problem of poor infection prevention and control effectIncrease intakeAntibacterial agentsAntimycoticsBiotechnologyHuman papillomavirus
The invention discloses microemulsion gel of an anti-human papillomavirus(HPV) plant extract and a preparation method and application of the microemulsion gel. The microemulsion gel comprises a plant extract and auxiliary materials, and the plant extract includes one or more of a rhizoma curcuma extract, a folium eucalypti extract, a radix sophorae flavescentis extract, a fructus cnidii extract, a radix stemonae extract and a cortex phellodendri extract. According to the invention, the natural plant extract not only can serve as a component of a carrier but also can serve as an active ingredient to enhance the medicine efficacy; by taking carbomer as a matrix, a local topical preparation with antibacterial, anti-inflammatory and antiviral functions is prepared; and the microemulsion gel used for HPV infection and prevention, bacterial and fungal vaginitis, cervical erosion, and daily care of women's private parts especially can reduce mRNA expression levels of key oncogenes E6 and E7 in Hela cells. The microemulsion gel prepared by the invention has high safety, high stability, convenience in administration and high patient compliance; and the processing technology is simple, cost is low and large-scale production is facilitated.
Owner:CHINA PHARM UNIV

Fusion protein for restoring function of failing immune cell and application thereof

The invention relates to a fusion protein for restoring a function of a failing immune cell. The fusion protein comprises a functional area for recognizing the failing immune cell and a functional area for conducting activation and amplification on the failing immune cell, and the two functional areas are connected through a non-functional amino acid fragment with a certain length, wherein the amino acid sequence of the fusion protein is the sequence shown in SEQ ID NO:5 or the sequence with similar functions and a similarity of at least 90%. The invention further relates to the application ofthe fusion protein. By means of the fusion protein, the failing immune cell can be recognized while other immune cells can be activated, amplified and recognized, and the function of killing antigenpositive cells of the immune cell is restored. Compared with the prior art, the proliferative utility on a CD 8 effector cell is further improved, the activation of the effector cell and the expression of a costimulatory molecule are enhanced, the restriction of tumor growth and the function of virus infection control can be further enhanced, and the fusion protein has good clinical prospect and wide application range.
Owner:科弈(浙江)药业科技有限公司

Intelligent system preparation for conditioning physiques and preventing and treating various psoriasis and preparation method

The invention discloses an intelligent system preparation for dialectically conditioning physiques and preventing and treating various psoriasis and a preparation method. For different physiques and etiology, pathogenesis and skin lesion characteristics of various psoriasis, 62 traditional Chinese medicines such as astragalus mongholicus and the like are respectively adopted and are subjected to steps of decocting and the like to prepare different formula preparations; by external application to related acupoints of the upper part (the Dazhui acupoint), the middle part (the Danzhong acupoint,the Shenque acupoint and the Guanyuan acupoint), the lower part (double Xuehai acupoints, double ZuSanli acupoints, double Sanyinjiao acupoints and double Yongquan acupoints) and an affected part (theashi acupoint) and oral administration, a five-in-one integral conditioning and preventing-treating integrated system is formed; and the intelligent system preparation is depended on an automatic dynamic integral regulation and control mechanism of a five-organ-in-one system of a human body, and implements intelligent dialectical physique conditioning and prevention and treatment. The intelligentsystem preparation disclosed by the invention has the effects of dispersing and descending, regulating lung and skin, clearing heat and dispelling cold, relieving exterior syndromes and removing freckles, warming yang and strengthening kidney, promoting water circulation and removing dampness, activating blood and dissolving stasis, detoxifying and dredging collaterals, reinforcing qi and nourishing blood, and dispelling wind and arresting itching, and is used for conditioning physiques and preventing and treating various psoriasis.
Owner:左耀武

External traditional Chinese medicine composition for treating skin diseases and using method of external traditional Chinese medicine composition

The invention belongs to the technical field of treatment of the skin diseases by traditional Chinese medicines, aims to solve the technical problems that existing skin diseases are difficult to cure, and symptoms are aggravated when the skin diseases are treated, and complications are severe, and provides an external traditional Chinese medicine composition for treating skin diseases and a using method of the external traditional Chinese medicine composition. The external traditional Chinese medicine composition comprises the following components in parts by weight: 0.5-2 parts of silicon iodide, 1-3 parts of manganese, 1-3 parts of potassium, 1-3 parts of sodium, 1-3 parts of Wuhan tobacco, 1-3 parts of brine, 0.5-2 parts of dandelion, 0.2-1 part of Rhizoma Acori Graminei, 0.1-0.5 part of Rhizoma Phragmitis, 0.1-0.5 part of Pericarpium Citri Reticulatae, 5-25 parts of green persimmons, 1-3 parts of Radix Sophorae Flavescentis, 0.1-0.5 part of Radix Astragali, 0.1-1 part of Fructus Cnidii, 0.1-0.3 part of Ramulus Cinnamomi, 0.2-0.8 part of Folium Artemisiae Argyi, 0.1-0.3 part of Rhizoma Kaempferiae, 0.5-2 parts of Fructus Kochiae, 0.1-0.5 part of Radix Stemonae, 0.5-2 parts of Rhizoma Atractylodis, 0.1-0.3 part of Cortex Eucommiae, 0.5-1.5 parts of Borneolum Syntheticum, 0.3-1 parts of Herba Menthae, 1-5 parts of Flos Carthami, 0.5-3 parts of old vinegar, 0.5-3 parts of glycerol, 1-4 parts of olive oil, 0.5-3 parts of SOD, 0.5-3 parts of banana peel and 20-100 parts of shea butter. By the external traditional Chinese medicine composition for treating skin diseases, skin inflammation is controlled effectively, effects of expelling wind and removing dampness, and improving immunity are achieved, the skin is not infected repeatedly again by sterilization and bacteria inhibition, the activity of the skin is activated, and the purpose of treating the skin diseases is achieved.
Owner:成都斌能节能环保科技有限公司

Traditional Chinese medicine anticancer agent

I study Neijing and Compendium of Materia Medica for many years, screen out natural medicinal materials which grow in China, and develop a special-acting drug-a traditional Chinese medicine anticanceragent which can resist malignant tumors in the middle and advanced stages. The agent is non-toxic, and has special effects on lung, stomach, liver, kidney, heart disease, esophagus, breast, thyroid,cervix, colorectal, leukemia and the like, and cure rate is much higher than 62%. For the human immunodeficiency virus, the agent can reduce a HIV viral load. The mechanism of the agent is to block anenergy source of cancer cells, resist the growth of tumor angiogenesis, enhance immune functions, (devour and destroy heterogeneity in blood), induce tumor cell apoptosis and block oncogene mutationand transcription. If the traditional Chinese medicine anticancer agent is taken, pain, nausea and vomiting are soon alleviated and disappeared. Diet is increased, sleep is improved, physical strengthis increased, and the development of the cancer cells is obviously controlled. A tumor block is softened, shrunk and disappeared. After two to three courses of treatment (three months after one course of the treatment), B-ultrasound or CT are used for re-examination of a patent with fast curative effect, a primary lesion disappears, no metastasis and recurrence occurs, and the patient has good health.
Owner:高良福
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