Anti-African swine fever virus and anti-CD double-target pig-derived antibody, preparing method and application

A technology for the preparation of African swine fever virus and antibodies, which is applied in the field of anti-African swine fever virus and CD dual-target swine-derived antibodies, which can solve the problems of inability to fight against the infection and spread of African swine fever, the inability to treat African swine fever, and the inability to prevent it. question
CN109734810APending Publication Date: 2019-05-10SHENZHEN JASON INTELLIGENT BIOTECH CO LIMLTED PRC
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHENZHEN JASON INTELLIGENT BIOTECH CO LIMLTED PRC
Publication Date
2019-05-10

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Abstract

The invention relates to the technical field of biological medicine, in particular to an anti-African swine fever virus and anti-CD double-target pig-derived antibody, a preparing method and application. The prepared anti-African swine fever virus and anti-CD pig-derived double-target compound antibody has two antigen combination sites which are combined with African swine fever viruses and immunecells respectively to generate the bridging effect and realize the two major functions; on one hand, the antigen proteins which cause immunosuppression and immune escape are inactivated, the immunosuppression and immune escape are eliminated, and the African swine fever viruses entering a body are killed; on the other hand, the functions of T cells are activated, the immune system is restored, the cell-mediated immunity is started, and virus expansion is prevented; meanwhile, infected cells are split and dissolved, phagocytes are activated to clear away the viruses and the infected cells, andthe aim of preventing and treating the African swine fever viruses is achieved. By means of the compound antibody, a biological medicine and a biological safety feed additive which eliminate the infection of the African swine fever viruses and prevent and treat the African swine fever can be prepared.
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Description

technical field

[0001] The invention relates to the technical field of biomedical engineering, and more specifically relates to an anti-African swine fever virus and CD dual-target swine-derived antibody, a preparation method and an application. Background technique

[0002] African swine fever (African swine fever, ASF) is an acute and severe infectious disease caused by African swine fever virus (ASFV). Not only seriously endanger the pig industry in my country and the world, but also seriously affect the international trade related to the pig industry and other related industries. The World Organization for Animal Health (Office international desépizooties, OIE) lists ASF as a must-report animal disease, and our country lists it as a first-class animal disease, which is an exotic disease that is focused on prevention and control.

[0003] Given that African swine fever is a complex disease that spreads rapidly around and invades the food chain causing major socio-economic...

Claims

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