9 results about "Barbituric acid" patented technology

The invention belongs to the technical field of methyl red azo dye purification, and discloses a methyl red azo dye adsorbent with good adsorption performance on a methyl red azo dye adsorbent, and a preparation method and application thereof. The preparation method comprises the following steps: (1) preparing a first precursor solution and a second precursor solution; the first precursor solution contains melamine, and the second precursor solution contains cyanuric acid and / or barbituric acid; (2) sequentially adding the first precursor solution and the second precursor solution into biomass carbon powder to form a reaction solution; enabling the supermolecule aggregate to grow in situ and coat the surface of the biomass carbon powder under a stirring condition to form a solid-liquid mixture; removing the solvent in the solid-liquid mixture, and drying to obtain a supramolecular composite precursor; (3) carrying out pressure molding on a mixture of the supramolecular composite precursor, silicate clay mineral and nickel salt to obtain a green body; and (4) carrying out heat treatment on the green body to obtain the methyl red azo dye adsorbent.

The invention discloses a polypropylene material which comprises the following components in parts by weight: 68-97 parts of polypropylene; 0.04 to 1.6 parts of polyethyleneimine; 0.05 to 0.6 part of barbituric acid or a derivative thereof; 0-12 parts of a toughening agent; and 0-35 parts of an inorganic filler. By introducing a specific content of polyethyleneimine and barbituric acid or a derivative thereof into the polypropylene material, the volatilization of aldehyde organic matters can be effectively inhibited, and the low glossiness of the polypropylene material can be effectively reduced.

The application discloses an oil oxidation type time-temperature indicator, which comprises a sealed container which is partially or wholly transparent, vegetable oil and a thio-barbituric acid color developing agent which are packaged in the sealed container. The application mixes the vegetable oil and the thio-barbituric acid color developing agent to prepare an oxidation indicator, and the oxidation degree of food containing the same vegetable oil can be indicated by using the color developing reaction of the vegetable oil oxidation product and the thio-barbituric acid color developing agent, and the color change is irreversible. The oxidation indicator is packaged in the sealed container which is partially or wholly transparent, so that the oil oxidation indicator with small volume, convenient use and direct indication is prepared. The problem that the color change of the existing time-temperature indicator for food containing vegetable oil is not obvious or reversible is solved.

The invention relates to the field of analysis and detection, in particular to a fluorescent probe as well as a preparation method and application thereof. The fluorescent probe provided by the invention is prepared by carrying out condensation reaction on barbituric acid and 2-hydroxy-1-naphthaldehyde in a polar solvent, a carbon-carbon double bond formed by condensation of barbituric acid and 2-hydroxy-1-naphthaldehyde is used as a key pi bridge in a molecule, and a chromophore with a strong intramolecular charge transfer effect is jointly constructed; the fluorescent dye shows cyan appearance and strong green fluorescence in an aqueous solution. After specific reaction with hypochlorite, a conjugated skeleton and an ICT process of the whole molecule are destroyed, so that the color of a solution is changed from cyan to colorless, fluorescence is remarkably quenched, and'off-on 'type detection is realized. The probe has the advantages of quick response, high sensitivity and good selectivity, can be applied to qualitative and quantitative detection of hypochlorite in environmental water quality and biological samples, and supports test paper portable detection.

This invention relates to a highly sensitive polarity and ONOO ‑ The dual-response fluorescent probe and its preparation method include the following steps: (1) adding 1,3-dicyclohexylbarbituric acid to acetic anhydride, and then adding boron trifluoride diethyl ether to react and obtain an intermediate product; (2) adding 7-(diethylamino)coumarin-3-carboxaldehyde, the intermediate product and piperidine to a first organic solvent, and after heating and reflux, extraction, filtration and recrystallization, obtaining the fluorescent dye LD-YB; (3) preparing the metal-organic framework material UiO with hafnium tetrachloride and organic ligands; (4) adding LD-YB and UiO to a second organic solvent, and reacting to obtain polar and ONOO. ‑ Dual-response fluorescent probe. This invention obtains polar and ONOO fluorescent probes by loading LD-YB onto UiO. ‑ The dual-response fluorescent probe improves detection accuracy and has good hydrophilicity.

The application belongs to the field of electrochemical synthesis, and discloses a method for preparing indane compounds under electrochemical conditions. The method uses inexpensive nickel as a catalyst to realize the cycloaddition reaction of 1,6-diynyl and alkyne under electrolytic conditions at room temperature, and rapidly and efficiently synthesizes indane compounds. The method can be applied to the cycloaddition reaction of 1,6-diynyl derived from the barbituric acid, a sedative and hypnotic, and 2,6-dichloro-5-fluoronicotinic acid ethyl ester, a medical intermediate, and synthesizes indane compounds containing a pharmacologically active fragment. The method has green and mild reaction conditions, does not need heating and uses a noble metal catalyst, has low reaction cost, and has good application value.

The application belongs to the technical field of methyl red azo dye purification, and discloses a methyl red azo dye adsorbent with good adsorption performance on methyl red azo dye, and a preparation method and application thereof. The preparation method comprises the following steps: (1) preparing a first precursor solution and a second precursor solution; the first precursor solution contains melamine, and the second precursor solution contains cyanuric acid and / or barbituric acid; (2) sequentially adding the first precursor solution and the second precursor solution into biomass carbon powder to form a reaction liquid; under stirring, in-situ growth of a supramolecular aggregate is realized and the supramolecular aggregate is coated on the surface of the biomass carbon powder to form a solid-liquid mixture; the solvent in the solid-liquid mixture is removed, and the supramolecular composite precursor is obtained through drying; (3) pressure forming a mixture of the supramolecular composite precursor, a silicate clay mineral and a nickel salt into a green body; and (4) performing heat treatment on the green body to obtain the methyl red azo dye adsorbent.

The application provides a continuous flow synthesis method of a Bose factor derivative, which comprises flowing reaction of D-glucose and dimethyl barbituric acid under alkaline conditions in a micro-channel reactor to synthesize 2,4(1H,3H)-pyrimidine dione-5-D-glucopyranosyl-6-hydroxy-1,3-dimethyl sodium salt, and flowing reaction of the reaction product with an oxidizing agent in another micro-channel reactor to obtain the Bose factor derivative (2ξ,3ξ)-3,7-dehydrated-N-methyl-D-glucosinamide. The continuous synthesis method of the Bose factor derivative has the advantages of short reaction time, simple operation, high automation degree, cheap and easily obtained reagent, high purity of the obtained product, and few impurities. Meanwhile, the preparation method has the advantages of high safety, large production capacity, high yield, reduced environmental pollution, and good application prospect.

The application provides a spiro-barbituric acid-epoxyhexane compound and a synthesis method and application thereof. A structural formula of the compound is as follows: wherein, a group R 2 is C 1‑6 alkyl, C 1‑6 alkoxy, hydrogen, halogen, halogenated C 1‑6 alkyl, nitro or naphthyl, a group R 3 is C 1‑6 alkyl, C 1‑6 alkoxy, hydrogen, halogen or naphthyl; and a group R 4 is C 1‑6 alkyl or benzyl. The application further provides a synthesis method of the compound, which comprises using an alkenyl barbituric acid compound and a 1,2-substituted allyl carbonate compound as raw materials, and under the action of a palladium catalyst, a chiral ligand and a base, asymmetric cycloaddition reaction is generated to synthesize a series of spiro-barbituric acid-epoxyhexane compounds. The synthesis method has the advantages of mild reaction condition, simple operation, wide applicable range of substrates, high yield and good stereoselectivity. It is tested that the compound has certain antitumor activity. The application provides an application of the compound in preparation of an antitumor drug.