87 results about "Indane" patented technology

The invention concerns a process for separating meta-xylene from a hydrocarbon feed comprising isomers containing 8 carbon atoms, comprising: a step for bringing said feed into contact with a faujasite type zeolite adsorbant, the water content of the adsorbant being in the range 0 to 1% by weight and the adsorption temperature being from 160° C. to 180° C.; a desorption step employing a solvent selected from toluene, indane and mixtures thereof.

This disclosure relates to a polymer that includes a first repeat unit and at least one end-cap group at one end of the polymer. The first repeat unit includes at least one imide moiety and at least one indane-containing moiety. The end-cap group is capable of undergoing a cycloreversion reaction. This disclosure also relates to a thermosetting composition containing the above polymer.

The present invention encompasses compounds of Formula (I): as well as the pharmaceutically acceptable salts and hydrates thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.

The present invention relates to indane derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

A method of inhibiting cell proliferation in a patient suffering from such disorder comprising administering to said patient an effective amount of a composition comprising, in admixture with a pharmaceutically acceptable carrier, a compound, or a pharmaceutically acceptable salt thereof, which is a substituted styrene compound which can also be a naphthalene, an indane or a benzoxazine; including nitrile and molononitrile compounds, and pharmaceutical compositions comprising, in admixture with a pharmaceutically acceptable carrier, a pharmaceutically-effective amount of such compound.

The invention discloses a chiral spiro phosphoramide derivative, which is a compound with a structural formula (1), a racemate or an optical isomer thereof. The chiral spiro phosphoramide derivative has a chiral spirobiindane skeleton, and is synthesized by adopting a 1,1'-spiro indane-7,7'-diphenol derivative with a spiro skeleton and a characteristics of optical activity as a chiral starting raw material. The chiral spiro phosphoramide derivative is a novel Bronsted acid organic small molecule catalyst, and can be widely used for catalysis of a plurality of asymmetric organic reactions.

Derivatives and conjugates of indinavir for generation of antibodies and labeled conjugates for use for detection of indinavir in biological samples. The derivatives are synthesized out of the indane ring hydroxyl group or the pyridine ring nitrogen of indinavir. Also disclosed is synthesis of a major metabolite of indinavir (M6) in a single step from indinavir using palladium catalyst and hydrogen gas. Indinavir M6 has been extended to synthesize various analogs of indinavir with suitable functional groups. These derivatives are useful in the development of indinavir immunogens, antibodies, and labeled conjugates in the development of indinavir immunoassays.

Reduced emissions in a jet fuel having aromatics content can be achieved by incorporating a quantity of an aromatic kerosene fuel blending component, preferably a bio-derived synthetic aromatic kerosene, comprising at least 90 wt. % of aromatics, less than 10 wt. % of indanes and tetralins and less than 1 wt. % of naphthalene into a jet fuel in a manner to meet the aromatic content specification for jet fuels. A jet fuel having aromatics content having reduced number-based nvPM emissions compared to equivalent total aromatics content petroleum-derived kerosene jet fuel is obtained.

The invention relates to a liquid crystal aligning agent, a liquid crystal alignment layer, a liquid crystal display element, polyamide acids and polyimides. The liquid crystal aligning agent provided does not deteriorate due to film absorbing water after liquid crystal alignment layer is formed and exposed to air for a while, has excellent coating peeling property and excellent printing performance. The liquid crystal aligning agent contains at least one polymer selected from a group consisting of polyamide acids and polymides obtained by dewatering cyclization of the polyamide acids, and the polyamide acids are obtained through reaction between diamines and tetracaboxylic dianhydrides. The liquid crystal aligning agent is characterized in that the diamines are special diamines having a structure of phenyl - indane and diamines containing carboxyl.

The invention discloses a device and a method for reclaiming and separating heavy component residue of a coked crude benzene hydrogenation process, and belongs to the technical field of rectification separation. The reclaiming device comprises a heavy component removal tower, a light component removal tower, a trimethyl benzene tower, an indane tower and a tetrahydronaphthalene tower connected sequentially; the bottom of each tower is communicated with a re-boiler, the top of each tower is communicated with a condenser, and the condenser is communicated with a vacuum system; the heavy component residue of the coked crude benzene hydrogenation process is continuously rectified and separated through the heavy component removal tower, the light component removal tower, the trimethyl benzene tower, the indane tower and the tetrahydronaphthalene tower in sequence, and trimethyl benzene, indane, tetrahydronaphthalene and naphthalene are obtained and respectively have purity of over 98.0 weight percent, 99.5 weight percent, 99.7 weight percent and 99.0 weight percent. The process has the advantages of reasonable flow, high reclaiming rate, low operating temperature, low process energy consumption, high product quality and the like, and is an efficient and feasible process for reclaiming and separating the heavy component residue of the coked crude benzene hydrogenation process.

Tetrahydroindene is dehydrogenated in a vapor phase in the presence of a metallic catalyst, e.g., a nickel-molybdenum catalyst, to produce indene, which is industrially useful in high yield while inhibiting the catalyst from suffering a decrease in activity. In particular, a higher yield can be attained by a method in which tetrahydroindene is dehydrogenated to first convert it into indane, which is further dehydrogenated to obtain indene.

The invention discloses a method for extracting, rectifying and separating pseudocumene and indane, which comprises the following steps: (1) using sulfolane as a solvent for extractive rectification, and adding the sulfolane and a raw material mixture into an extractive rectification tower according to a certain proportion; (2) after separation, leaving the high-purity pseudocumene at the tower top, and leaving the sulfolane solvent and the indane at the tower bottom; (3) delivering the tower bottom material into a solvent regeneration tower to carry out distillation operation, wherein an extract at the tower top is the indane, and the tower bottom is the sulfolane solvent; and (4) delivering the solvent sulfolane at the tower bottom back to the extractive rectification tower for recycling. A product of the method is the pseudocumene of which the purity is more than or equal to 99.5 percent; and the extracted and rectified sulfolane solvent can be recycled, and simultaneously the reclaiming rate of the indane is more than or equal to 97 percent. Compared with the conventional common distillation method, the purity of the product is higher, the reclaiming rate is higher, and the energy consumption is lower.

The invention discloses a C9 heat polymerization type petroleum resin product with a light color and a high softening point and a preparation process thereof, and belongs to the technical field of petroleum resin preparation. The preparation method includes the following steps that C9 aromatic hydrocarbon fraction, which is a by-product of a cracking ethylene plant, serves as the main raw material, first the C9 raw material oil is subjected to rectification treatment to obtain a de-weighted C9 raw material; then, the de-weighted C9 raw material, dicyclopentadiene, methyldicyclopentadiene, indene, indane and the like are accurately weighed according to a certain proportional relationship, dissolved in a solvent oil and added into a thermal polymerization reactor, a the reaction initiator isadded, the mixture is stirred to be uniform, polymerization is carried out under a nitrogen atmosphere and normal pressure, the polymerized reactant is treated by a stripping device for recovering the solvent, and then the C9 heat polymerization type petroleum resin is obtained. According to the C9 heat polymerization type petroleum resin product with the light color and the high softening pointand the preparation process thereof, the C9 heat polymerization type petroleum resin suitable for the paint industry can be prepared by adjusting the contents of some components in the reaction materials and adding the reaction initiator.

The invention discloses an aromatic air disinfectant spray special for wards and a preparation method thereof, and belongs to the technical field of medical disinfection. The aromatic air disinfectantspray special for the wards is prepared from the following raw materials: carboxymethyl isomaltooligosaccharide, triethanolamine, nano zinc oxide, Chinese prickly ash extract, hydroxyl indane musk, benzoin resin, chitosan, activated carbon, rhizoma atractylodis, radix angelicae dahuricae, radix rehmanniae preparata, green tea, amino silicone oil, apple juice, and deionized water. The disinfectantspray of the invention is used for disinfecting the wards, can keep the fragrant and apple complex flavor in a ward, has an effect of adjuvant treatment of disease, greatly improves an adjuvant treatment rate, and has a certain inhibitory effect on escherichia coli and staphylococcus aureus, and the inhibitory rates are 94.14% to 96.34% and 92.57% to 94.33% correspondingly.

The invention discloses a method for preparing donepezil hydrochloride. The method prepares the donepezil hydrochloride by five steps of reduction reaction for preparing 5,6-dimethoxy-2-(-4-piperidine methyl)-indane-1-ketone acetate, condensation, reduction, substitution and closed ring decarboxylation. The preparation method has the advantages of easily obtained and cheap raw materials, simple synthesis operation, mild reaction conditions, good reaction selectivity and good yield, and is easy to control and suitable for industrialized production.

The invention relates to preparation methods and applications of a chiral spirophosphine-nitrogen-phosphine tridentate ligand SpiroPNP and an iridium catalyst Ir-SpiroPNP thereof. The chiral spirophosphine-nitrogen-phosphine tridentate ligand is a compound represented by a formula I, or a racemate or an optical isomer thereof, or a catalytically acceptable salt thereof, and is mainly structurallycharacterized by having a chiral spiro indane skeleton and a phosphine ligand with a large steric hindrance substituent. The chiral spirophosphine-nitrogen-phosphine tridentate ligand can be synthesized by taking a 7-diaryl / alkylphosphino-7'-amino-1,1'-spiro indane compound with a spiro skeleton as a chiral starting raw material. The iridium catalyst of the chiral spirophosphine-nitrogen-phosphinetridentate ligand is a compound represented by a formula II which is described in the specification, or a raceme or an optical isomer, or a catalytically acceptable salt thereof, can be used for catalyzing asymmetric catalytic hydrogenation reaction of carbonyl compounds, particularly shows high yield (greater than 99%) and enantioselectivity (as high as 99.8% ee) in asymmetric hydrogenation reaction of simple dialkyl ketone, and has practical value.

The invention provides a novel fire retardant tri(1,3-dioxa-2-phospho hetero-2-oxo-1,2-indane) m-cresyl phosphate and a preparation method thereof. The novel fire retardant is characterized in that the structural formula of the novel fire retardant is shown in a formula I. By using the preparation method, the novel halogen-free phosphorus fire retardant is synthesized, the novel halogen-free phosphorus fire retardant has the advantages of good antiflaming effect, environment friendliness and no pollution as well as good degradability. Simultaneously, the fire retardant is simple and availablein raw material, is low in cost, and has strong practicability.

The invention relates to a treatment method for recovering pentamethyl indane in galaxolide production. The treatment method comprises the following steps: adding a certain amount of ferrous sulfate into a recovered pentamethyl indane solution, and slowly and dropwise adding a certain amount of concentrated sulfuric acid to provide an acidic environment; after the concentrated sulfuric acid is dropwise added, controlling a certain temperature, dropwise adding hydrogen peroxide and carrying out Fenton oxidation reaction; after dropwise adding is completed, carrying out heating to a certain temperature to continue the reaction, and after the reaction is completed, conducting standing for layering and separating out lower-layer acid water; adding excessive alkaline water into an upper-layer pentamethyl indane phase for neutralization; and after neutralization is completed, separating out lower-layer alkaline water to obtain treated pentamethyl indane. According to the method, the conversion rate of pentamethyl indane is increased, production cost is reduced, production efficiency is greatly improved, the reaction efficiency and the material utilization rate of the whole production process are optimized, and the economic benefits of enterprises are increased.

The present invention relates to an improved process for producing alkyl substituted indanes which are used in the synthesis of fragrance ingredients for perfumery applications.

The invention belongs to the field of organic optoelectronics and discloses an electroluminescent monomer and polymer and preparation and application methods thereof. The structural formula of the electroluminescent polymer is shown as follows, which introduces a naphthalene nucleus on the structural basis of 10, 12-indane[2, 1-b] fluorene, accordingly, not only can the advantages of the 10, 12-indane[2, 1-b] fluorene which can effectively inhibit production of exciplexes and shortening of conjugated length to lead to movement of luminescent wavelength towards short wavelength and further to facilitate emission of purer blue light be retained, but also, by means of an asymmetric structure, the electroluminescent polymer can facilitate formation of amorphous film to inhibit fluorescence quenching. The electroluminescent polymer is high in dissolving property and applicable to processing solution, reducing device production costs as well as preparing large-area flexible OLED (organic light emitting diode) devices, and saves annealing treatment during production of electroluminescent devices, thereby being simple in production processes and having a huge potential and prospect for development in the field of organic electronic display.

Provided are compounds which are an NMDA antagonist having a broad safety margin and are useful as a treating agent or a preventing agent for Alzheimer's disease, cerebrovascular dementia, Parkinson's disease, ischemic apoplexy, pain, etc. Concretely provided are an amine derivative or its salt characterized in that the amine-containing structure A therein bonds to a 2- or 3-cyclic condensed ring (e.g., indane, tetralone, 4,5,6,7-tetrahydrobenzothiophene, 4,5,6,7-tetrahydrobenzofuran, 7,8-dihydro-6H-indeno[4,5-b]furan, 2,3-dihydro-1H-cyclopenta[1]naphthalene) via X 1 (bond or lower alkylene); and an NMDA antagonist containing it as an active ingredient thereof.A compound useful as an NMDA antagonist having a wide safety region which is a therapeutic agent for Alzheimer's disease, vascular dementia (vascular agnosia), Parkinson's disease, ischemic apoplexy, and pains or a preventive agent for these. The compound is an amine derivative or salt thereof characterized by comprising an amine-containing structure (A) and a di- or tricyclic fused ring (indane, tetralone, 4,5,6,7-tetrahydrobenzothiophene, 4,5,6,7-tetrahydrobenzofuran, 7,8-dihydro-6H-indeno[4,5-b]furan, 2,3-dihydro-1H-cyclopenta[a]naphthalene, etc.) bonded to the structure (A) through X<1> (a bond, lower alkylene, etc.). The NMDA antagonist contains the derivative or salt as an active ingredient.

The present invention belongs to the field of chemical technology. During the catalytic synthesis of AMS cyclic dimer 1,3,3-trimethyl-1-phenyl indane, alpha-methyl styrene is used as raw material andammonium salt type ionic liquid R3NHX-MaXb is used as catalyst, where R is C2-C10 alkyl or aryl, HX is inorganic acid or organic acid and MaXb is inorganic acid or organic acid salt. The catalyst amount accounts for 2-25 wt% of total material and reaction temperature is controlled in 25-100 deg.c. After finishing the reaction, the reacted mixture is cooled, settled and separated to obtain the product. The production process has mild reaction condition, low cost, no volatilization of organic solvent and other advantages.

The invention relates to a chiral spiro phosphoric acid dirhodium complex as well as a preparation method and application thereof. The chiral spiro phosphoric acid dirhodium complex is a compound shown in a formula I, can be prepared by reacting phosphoric acid with a chiral spiro indane skeleton with rhodium acetate, and is mainly structurally characterized in that four chiral spiro phosphoric acid anions are coordinated to two rhodium atoms. The complex can catalyze the insertion reaction of carbene derived from diaryldiazo to a silicon-hydrogen bond to prepare a chiral organosilicon compound.

Disclosed are compounds for medical uses, for example, compounds of formula (Ia), wherein A1, A2, A3, A4, A5, A6, A7, R6, R7 and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.

Provided is a solution comprising a polymer and an organic semiconductor compound, wherein the semiconductor compound is a thiophene derivative, and wherein the solvent is a mixture comprising a) at least one of 4-methyl anisole, indane and an alkylbenzene with a linear or branched alkyl group containing from 4 to 7 carbon atoms; and b) at least one of tetrahydronaphthalin and 1,2,4-trimethylbenzene.

The present invention provides a sulfonated coal tar distillate salt polymer that is a condensation product of an aldehyde, preferably formaldehyde, and a sulfonated middle fraction obtained during coal tar distillation. The middle fraction includes from about 40% to about 95% by weight naphthalene and from about 5% to about 60% by weight of a plurality of compounds selected from the group consisting of quinoline, indene, biphenyl, indane, acenaphthene, anthracene, phenanthrene, methyl naphthalene, cresol, phenol, xylenol, and tetralin. The present invention also provides a method of forming a sulfonated coal tar distillate salt polymer. The method includes sulfonating the middle fraction to form a middle fraction sulfonic acid mass, optionally adding a first portion of water to the middle fraction sulfonic acid mass to form a mixture, reacting the mixture and an aldehyde to form a condensate, optionally adding a second portion of water to dilute the condensate, and adding a base to form a sulfonated middle fraction salt polymer. Sulfonated middle fraction salt polymers formed in accordance with the method of the invention are useful as dispersants and plasticizers in aqueous cementitious slurries.

This invention relates to a solvent for crystallizing and purifying anthracene series products, which is composed of toluene, xylene, trimethylbenzene, styrene, benzofuran, indane and indene, wherein the sum of toluene, xylene and trimethylbenzene is 70-95 wt.%; the sum of xylene and styrene is 70-90 wt.%; the sum of benzofuran, indane and indene is 1-5 wt.%. The solvent can increase the washing and separation abilities to the impurities in the anthracene range in tar, improve the purification effect of anthracene and carbazole, and increase the yield.