117 results about "Phosphoramide" patented technology

The invention discloses a hyperbranched polyphosphoramidate and a preparation method thereof. The preparation method of the hyperbranched polyphosphoramidate comprises that one or more B' B2 type hydramine monomers and one or more A2 type monomers selected from phenyl dichlorophosphate, isopropyl phosphonic dichloride, ethyl dichlorophosphite and the like are heated to undergo a reaction in the presence of at least one catalyst under a nitrogen protective atmosphere; reaction products are subjected to solution polymerization to form an AB2 type monomer; and the AB2 type monomer is subjected to further polycondensation to form the hyperbranched polyphosphoramidate. The hyperbranched polyphosphoramidate has the characteristics that a skeletal structure of the prepared hyperbranched polyphosphoramidate contains phosphatide bonds and phosphamide bonds and thus the hyperbranched polyphosphoramidate has good biodegradability; reaction raw materials of the hyperbranched polyphosphoramidate have wide sources; the reaction raw materials are commercial monomers; and the hyperbranched polyphosphoramidate is prepared by typical condensation polymerization. The preparation method has the advantages of mature synthesis way, simple reaction devices, operation and separation purification processes, and high product yield. Ends of molecular chains of the prepared hyperbranched polyphosphoramidate contain a lot of function groups and thus the prepared hyperbranched polyphosphoramidate can react with multiple active groups. The hyperbranched polyphosphoramidate has a wide application prospect especially in a biological material field.

The invention discloses a deoxyribonucleic acid (DNA) base analogue with a photo-crosslinking group biaziridine and a synthetic method thereof, and relates to the DNA base analogue and the synthetic method thereof. The DNA base analogue with the photo-crosslinking group biaziridine is a biaziridine phosphoramidite monomer; an intermediate product with two hydroxyl groups is connected on the basis of a compound 1; a material 1-amino-hexylene glycol is led; an amido bond is formed under condensation of dicyclohexylcarbodiimide and 1-hydroxybenzotriazole, so as to obtain an immediate product 2; the material 4-4'-dimethoxy triphenyl methyl chloride is led; pyridine and dichloromethane are taken as solvents; an immediate product 3 is obtained under catalytic action of 4-dimethylamino-pyridine; the material 2-cyanoethyl N, N-diisopropyl chlorinated phosphoramide is led; N,N-diisopropylethylamine is taken as alkali and a catalyst; dichloromethane is taken as a solvent, so as to obtain the final product under the condition of anaerobic reaction without water.

The invention relates to a copolymerized flame-retardant polyamide fiber and a preparation method thereof. The preparation method comprises the following steps that a flame-retardant polyamide copolymer serves as all or part of spinning raw materials for spinning to obtain the copolymerized flame-retardant polyamide fiber, wherein the flame-retardant polyamide copolymer is prepared by mixing a flame retardant salt with a polyamide 66 oligomer and / or a polyamide 6 oligomer and then carrying out condensation polymerization, the flame retardant salt is prepared from N,Ndi (6aminohexyl) phenyl phosphoramide and binary acid HOOCR1COOH through a high-temperature and high-pressure reaction, the temperature of the high temperature is 210-220 DEG C, and the pressure of the high pressure is 1.7-1.9MPa, and the main material of the finally prepared copolymerized flame-retardant polyamide fiber is the flame-retardant polyamide copolymer. The preparation method is simple to operate, the flame-retardant polyamide copolymer is excellent in flame retardance and good in spinnability, and the prepared copolymerized flame-retardant polyamide fiber is a functional fiber with flame retardance and canbetter meet the requirements of the fields of medical treatment and public health, professional clothing, clothing home textiles and the like in modern life on the flame-retardant polyamide fiber.

The invention relates to a method for preparing flame-retardant polymer polyol from phosphamide. The method mainly comprises the following steps: a, reacting phosphoryl dichloride with organic diaminein a nitrogen atmosphere, adding an acid-binding agent, reacting at 60 DEG C for 2 hours, and filtering to obtain a colorless transparent solution; and b, adding a formaldehyde solution into the phosphamide solution obtained in the step a, heating to react for a period of time, mixing the obtained solution with polyether polyol, heating to react completely, and vacuumizing to remove residual monomers to obtain the flame-retardant polymer polyol with the nitrogen content of 6-9% and the phosphorus content of 3-5% in terms of the weight of the polymer polyol. The polyurethane foam plastic prepared from the flame-retardant polymer polyol has a foaming foam oxygen index of about 30%, good flame retardancy and low smoke generation amount.

The invention provides a cyclohexanediamine-derived phosphamide chiral ligand as well as a preparation method thereof and an application thereof. The method comprises the following steps of: first, protecting one amino of chiral source cyclohexanediamine by using phthalic anhydride; and after the chiral source cyclohexanediamine is acylated with dialkyl phosphoryl chloride, removing a protecting group by using hydrazine hydrate; and performing N-alkylation reaction on the chiral source cyclohexanediamine and halohydrocarbon, so as to obtain the phosphamide chiral ligand. According to the invention, the phosphamide chiral ligand can be used for catalyzing asymmetric addition reaction of zinc alkyl and a carbonyl compound; the yield of an addition product is high up to 99 %; and the enanitomer selectivity ee value is high up to 96 %.