The invention relates to a traditional Chinese medicine preparation for treating peptic ulcer. The preparation is composed of the following traditional Chinese herbals: cuttlefish bone, banksia rose, dittany bark, rhizoma corydalis, pseudo-ginseng powder, dark plum, rheum officinale, bletilla striata, Korean pine bark charcoal, chorion ovi, curcuma tuber, indigo naturalis, borneol, pomegranate rind, scorched bighead atractylodes rhizome, radix bupleuri, and adenophora root, and has the functions of neutralizing acid, astringing ulcer, activating blood, removing stasis, promoting tissue generation, regulating qi, relieving pains, soothing the liver, invigorating the stomach, warming the middle, and dissipating cold. The drug directly acts on the internal organs after being orally taken, is capable of reducing the acid concentration in stomach and improving the pH value of the stomach, can reduce the pepsin activity, promote the repairing of gastric mucosa, and strengthen the defensive performance of gastric mucosa, can also promote the proliferation of mucosa cells, and maintain the integrity of mucosa, moreover, is capable of inhibiting the activity of gastric wall cells and acid secretion caused by various irritants, promotes the gastric dynamic to recover the self-adjusting performance of the digestive system, can radically eliminate the symptoms such as nausea, emesis, abdominal distention, and the like, and finally radically cures the peptic ulcer.