The invention discloses a supramolecular composition for resisting
sunlight damage as well as a preparation method and application of the supramolecular composition, and belongs to the technical field of
cosmetics. The supramolecular composition disclosed by the invention is prepared from
nicotinamide, 4-hydroxyethylpiperazine
ethanesulfonic acid and
riboflavin. The invention also provides a preparation method of the supramolecular composition, which comprises the following steps: S1, mixing the
nicotinamide, the 4-hydroxyethylpiperazine
ethanesulfonic acid and the
riboflavin according to the proportion, heating in
inert gas, and assembling the components into the liquid supramolecular composition by using a
microwave-assisted method after the components are completely molten; and S2, cooling the supramolecular composition obtained in the step S1, performing
vacuum drying, and crushing into
powder to obtain the supramolecular composition. The supramolecular composition is constructed through specific component combination, and the photoresponse characteristic is changed to inhibit generation of photosensitive by-products; all the components have a synergistic effect, so that respective light protection characteristics can be retained, a stable structure can be formed through
intermolecular interaction, and the technical limitations that a traditional
single component is easy to inactivate and single in function are overcome.