The invention discloses a traditional Chinese medicine water-honeyed pill for treating gout and a preparation method of the pill, which belongs to the field of traditional Chinese medicine. The effective component of the traditional Chinese medicine water-honeyed pill is prepared from the following raw material medicines: 30 g of rhizoma smilacis glabrae, 20 g of astragalus membranaceus, 20 g of radix achyranthis bidentatae, 20 g of polygonum cuspidatum, 15 g of caulis spatholobi, 15 g of angelica, 15 g of rhizoma alismatis, 15 g of turmeric, 15 g of large-leaved gentia, 15 g of salvia miltiorrhiza, 15 g of radix clematidis, 10 g of radix stephaniae tetrandrae, 10 g of notopterygium root, 10 g of trogopterus dung, 15 g of ligusticum wallichii, 10 g of myrrh, 10 g of semen brassicae, 10 g of stiff silkworm, 10 g of moutan bark, 10 g of golden cypress, 10 g of fructus liquidambaris, 12 g of radix bupleuri, 10 g of immature bitter orange, 10 g of rhizoma cyperi, 10 g of radix curcumae, 10 g of cassia twig, 10 g of monkshood, 6 g of peach kernel and 6 g of safflower. The traditional Chinese medicine water-honeyed pill has the functions of promoting blood circulation to remove meridian obstruction, clearing away heat and removing dampness, cooling blood and inducing dieresis, and soothing the liver and strengthening the spleen. The traditional Chinese medicine water-honeyed pill is good in curative effect, safe in medication, economical, reliable, and the like, and can effectively inhibit the development of gout and perfect the symptoms and signs of patients, and the curative effect is significant.