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Multi-Active Microtargeted Anti-Aging Skin Cream Polymer Technology

a skin cream and multi-active technology, applied in the direction of peptides, medical preparations, plant/algae/fungi/lichens ingredients, etc., can solve the problems of high side effects, prescription, irritation of sensitive skin types, etc., and achieve the effect of reducing the signs of aging and without exacerbating acn

Inactive Publication Date: 2011-12-15
MACRENE ACTIVES LLC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0021]The anti-aging and skin rejuvenation cream and lotion compositions of the current invention include a unique composition with DNA repair molecules, polyphenols from a variety of plant sources, amino acids, hyaluronic acid in small molecular weights, antioxidants of all classes, UV repair molecules of all classes, peptides and rich emollients that are combined actively to reduce wrinkles, reverse sun damage, diminish redness and abnormal pigment, and improve the signs in the various categories of skin aging. The present invention is to be applied daily on the skin to obtain results in reducing wrinkles, redness and abnormal discolorations that result from UV damage and aging. The present invention also yields the unexpected finding of dramatic reduction in redness and improvement in acne and rosacea. The composition includes:
[0032]Accordingly, it is a principal object of the invention to provide topical cream and lotion compositions for applying to the skin to comprehensively address all categories of skin aging with actives encompassing all categories of anti-aging activity, including reducing the appearance of wrinkles, laxity, redness, brown discoloration, elastosis, UV damage, poor texture, and abnormal skin growths.
[0034]It is a further object of the invention to provide topical skin cream and lotion compositions that reduce the signs of aging.
[0035]Still another object of the invention is to provide a topical skin cream and lotion composition that leaves the skin feeling soft to the touch without exacerbating acne.

Problems solved by technology

Topical tretinoin cream has been shown to reduce wrinkles but has a high incidence of side effects and requires a prescription.
Alpha-hydroxy acids have been reported to increase the risk of sunburn and are also irritating to sensitive skin types.
Over-the-counter skin care preparations are generally inadequate in providing anti-aging results, and often make the skin feel greasy and exacerbate acne, as they often include petrolatum or mineral oil.
Their moisturizing qualities also tend to vanish quickly, and they tend to yield little, if any, results in the aforementioned categories of skin aging.
In addition, many include potentially toxic parabens, propylene glycol and fragrances, which are irritants.
Prior scientific research has shown the efficacy of small combinations of few active substances to target a specific category of skin aging, but the comprehensive combination of multiple classes of active substances systematically targeting the various categories of aging has not been carried out.
Finally, the plethora of anti-aging skin products on the market which contain very few ingredients demonstrated in the published literature to provide clinical results to the skin has resulted in confusion in the market among consumers and skin care providers alike.
Additionally, glycolic acid when used regularly is irritating to sensitive skin, and photosensitizing, increasing the risk of sunburn.
However, the skin cream of Mausner is lacking plant-derived polyphenols and antioxidants, and contains the undesirable propylene glycol and animal- or human-derived ingredients (serum proteins).
This composition by Mausner contains retinol, which is an irritant to many users, propylene glycol, which has been reported to result in untoward effects and potential toxicity and animal- or human-derived agents, such as serum proteins.
In addition, the composition lacks DNA repair, peptides and most classes of plant-derived polyphenols.
However, the composition is lacking in amino acids, DNA repair, peptides and polyphenols, and conversely contains propylene glycol, which is sensitizing and retinol, which has a high incidence of irritation to sensitive skin types.
The patents do not define the various categories of skin aging nor do they rigorously define the various categories of actives with respect to clinical outcome.
In addition, none of the prior art included Ilex paraguensis extract in skin cream compositions heretofore described.

Method used

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  • Multi-Active Microtargeted Anti-Aging Skin Cream Polymer Technology
  • Multi-Active Microtargeted Anti-Aging Skin Cream Polymer Technology
  • Multi-Active Microtargeted Anti-Aging Skin Cream Polymer Technology

Examples

Experimental program
Comparison scheme
Effect test

production example 1

Cream

[0067]Multi-Active Anti-Aging Cream Base. For making the cream polymer base, combine in a beaker the hydrogenated lecithin, sodium methyl stearoyl taurate, glycerin and squalane with hydroxypropylmethylcellulose stearoxy ether. Homogenize. To this, add the phenoxyethanol, caprylyl glycol, ethylhexylglycerine, hexylene glycol, water, xantham gum, Tremella fuciformis polysaccharide, glycerin, disodium EDTA, and caffeine. At this point, homogenize for 10 minutes then mix and begin heating to 80 degrees C. The next step is to mix sorbitan stearate, cetyl alcohol, Helianthus annus seed oil unsapofiniables, Santalum album extract, Phillodendron amurense bark extract, Hordeum distichon extract, trimethylopropane tricaprylate / tricaprate, dimethicone, tetrahexyldecyl ascorbate and stearic acid. Cool to 25 degrees C.

[0068]The next step involves the addition of the DNA repair actives and amino acids. Acetyl tyrosine, proline, hydrolyzed vegetable protein, adenosine triphosphate are added ...

production example 2

Cream

[0073]Multi-Active Anti-Aging Cream (Base) with the following alteration: replace acetyl tetrapeptide-2 with palmitoyl oligopeptide and palmitoyl tetrapeptide-7.

[0074]The preferred method of making the skin rejuvenation cream of Example 2 is the same as in Example 1. This cream works particularly well for very wrinkled skin.

production example 3

Cream

[0075]Multi-Active Anti-Aging Cream (Base) with the following alteration: addition of Camellia sinensis extract.

[0076]The preferred method of making the skin rejuvenation cream of Example 3 is the same as in Example 1. This cream works particularly well for very inflamed, sensitive skin and skin with abnormal lesions.

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Abstract

A comprehensive, single agent cosmetic cream or lotion containing a high number of ingredients that target anti-aging in a defined manner. The cream or lotion contains a high number and variety of active substances that demonstrate excellent safety and efficacy in all of the various defined categories of skin aging, including but not limited to wrinkles, abnormal pigment or brown spots due to aging of the skin and an unexpectedly high efficacy in the reduction of redness and acne and rosacea blemishes.

Description

CROSS-REFERENCE TO RELATED APPLICATION[0001]This application claims priority from a previously filed provisional application Ser. No. 61 / 352,956, filed Jun. 9, 2010, entitled “Multi-Active Microtargeted Anti-Aging Skin Cream Polymer Technology,” by the same inventor.BACKGROUND OF THE INVENTION[0002]1. Field of the Invention[0003]The present invention relates to a comprehensive multi-active anti-aging and skin rejuvenation cream and lotion especially beneficial for the various categories of skin aging, including but not limited to wrinkles, redness and abnormal pigment or brown spots and is associated with an unexpected result in the dramatic reduction of redness, acne and rosacea.[0004]2. Description of the Prior Art[0005]The need for anti-aging creams / lotions and moisturizers without a prescription is evident. Topical tretinoin cream has been shown to reduce wrinkles but has a high incidence of side effects and requires a prescription. Alpha-hydroxy acids have been reported to incr...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K8/97A61Q19/00A61Q19/08A61K8/96
CPCA61K8/922A61K8/678A61Q19/08A61K8/11A61K8/14A61K8/553A61K8/92A61K8/96A61K8/975A61Q17/04A61Q19/00A61K8/31A61K8/34A61K8/345A61K8/347A61K8/35A61K8/365A61K8/44A61K8/4913A61K8/4946A61K8/735A61K8/891A61K8/4953A61K8/64A61K8/645A61K8/676A61K8/97A61K8/9728A61K8/9789A61K8/9794
Inventor ALEXIADES-ARMENAKAS, MACRENE
Owner MACRENE ACTIVES LLC
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