5results about How to "Enhance skin barrier function" patented technology

The invention belongs to the technical field of biology, and particularly relates to recombinant escherichia coli for producing melonic acid and application of the recombinant escherichia coli. Escherichia coli MG1655 is used as a host cell, and HMG-CoA synthetase MvaS gene and HMG-CoA reductase MvaE gene derived from lactobacillus casei, acetyl-coenzyme A acetyltransferase atoB gene derived from escherichia coli, phosphoketoenzyme fxpk gene derived from bifidobacterium adolescentis and fructose-1, 3-D-glucanase derived from escherichia coli are synthesized into an HMG-CoA synthetase MvaS gene and HMG-CoA reductase MvaE gene derived from lactobacillus casei. And transferring the 2, 6-diphosphatase fbp gene into Escherichia coli host cells to obtain the gene. The recombinant Escherichia coli constructed by the invention can be used for synthesis of the melonic acid, the yield of the melonic acid can reach 87.86 g / L after the recombinant Escherichia coli takes glucose as a substrate and is fermented for 48 hours in a 5L fermentation tank at 37 DEG C, and the recombinant Escherichia coli has the advantages of short fermentation time and high yield and meets the requirements of industrial production.

The invention provides application of recombinant collagen in preparation of a preparation for improving the expression quantity of genes related to a skin barrier function. The amino acid sequence of the recombinant collagen is shown as SEQ ID NO: 45. The expression conditions of a series of related genes capable of enhancing the skin barrier function are detected in a transcriptomics mode, and it is proved that the recombinant collagen provided by the invention can promote the expression of the related genes capable of enhancing the skin barrier function. The collagen can be used for development and application of various cosmetic products, and the cosmetic products are endowed with the efficacy and effect of maintaining the skin barrier function. Meanwhile, a series of screened genes related to the skin barrier function can also be used as references for evaluating the effect of enhancing the skin barrier function by other raw materials or cosmetics.

The invention provides nicotinamide whitening, moisturizing and beautifying cream and a preparation method thereof, and belongs to the technical field of cosmetics. According to the nicotinamide whitening, moisturizing and beautifying cream, the nicotinamide derivative, the fermentation extract and other components are added, so that the prepared nicotinamide whitening, moisturizing and beautifying cream has better functions of whitening, moisturizing, diminishing inflammation, resisting bacteria and enhancing skin barrier, the absorption of active components by skin can be improved, the addition amount of the active components is reduced, the cost is reduced, the effect is improved, and the nicotinamide whitening, moisturizing and beautifying cream has a good application prospect. Wide application prospects are realized.

The present disclosure relates to skin care compositions, skin care products, and methods for providing at least one skin care benefit in a subject in need thereof. More specifically, the present disclosure relates to methods and compositions comprising a Bacillus subtilis ferment, a Bacillus subtilis ferment extract, or a fraction thereof for reducing dandruff, reducing scalp or skin disorders, enhancing skin barrier, improving skin barrier function, moisturizing skin, and any combination thereof.

The invention discloses a preparation method of a constant-water-coagulation moisturizing component and cosmetic application of the constant-water-coagulation moisturizing component, and relates to the technical field of cosmetics. According to the preparation method of the constant-water-coagulation moisturizing component, glycosylglycerol is prepared by adopting taklamaya desert algae in a mode of combining salt stress and enzyme catalysis, the content of the prepared glycosylglycerol is high, and the glycosylglycerol is more beneficial to activation and promotion of cell regeneration; the cell activity is enhanced and the cell metabolism is accelerated; the cell oxidation resistance is enhanced; and collagen synthesis is promoted. The composition is matched with carbohydrate isomeride, sodium hyaluronate, ceramide, squalane and other components to form a constant-water-coagulation moisturizing component, and the constant-water-coagulation moisturizing component is applied to cosmetics and can improve the water content of the cuticle of the cheek skin and reduce the transepidermal water loss rate of the cheek skin.