The invention belongs to the technical field of testing or analyzing materials by means of the chemical or physical properties of determination materials, and discloses a double-mode Raman-
optical projection tomography system. A
laser beam subjected to beam expanding through a
beam expander shines a sample, all
modal optical signals are separated through a spectroscope,
signal collection is conducted by adopting sparse sampling, an optical transmission projection
signal collection module collects sample transmission light, and an optical
projection image is formed; a multispectral Raman scattered
signal collection module collects Raman scattered signal generated by the sample; collected data is subjected to
background noise removing; sparse sampling data is rebuilt by adopting ART based ona TV minimization algebraic
reconstruction method; a three-dimensional structure image and a three-dimensional
chemical composition image which are obtained through rebuilding are blended, and a three-dimensional volume image containing multiple information is obtained. Accordingly, Raman
spectral imaging and
optical projection tomography are skillfully combined to the same
system, triple information is provided, and information fit is high; the large scale sample imaging speed is high, and operation is easy and flexible.