Focusing supersonic modulation reflection type optical chromatography imaging method and its apparatus

An optical tomography and focused ultrasound technology, applied in the field of biomedical imaging, can solve the problem of difficult to achieve accurate measurement of deep tissue, and achieve the effect of practicability, high resolution, and improved signal-to-noise ratio.

Inactive Publication Date: 2003-06-11
SOUTH CHINA NORMAL UNIVERSITY
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Problems solved by technology

It is a non-destructive testing technology, not only has high optical detection accuracy, resolution can reach micron level, but also can perform functional imaging, which is of great significance for distinguishing diseased tissues in living biological tissues, because some diseased tissues have physical characteristics or There is no difference or little difference between the appearance and normal tissue,

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  • Focusing supersonic modulation reflection type optical chromatography imaging method and its apparatus
  • Focusing supersonic modulation reflection type optical chromatography imaging method and its apparatus
  • Focusing supersonic modulation reflection type optical chromatography imaging method and its apparatus

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Embodiment

[0033] The working process is as follows:

[0034] (1) The laser light emitted by the laser 1-1 with a wavelength of 632nm is polarized by the polarizer 1-2, coupled into the optical fiber 1-3, and incident into the biological tissue simulation medium through the central hole of the ultrasonic transducer 2-3;

[0035] (2) computer 5 controls function generator 2-1 to produce the electric signal of ultrasonic frequency, input to power amplifier 2-2, drives ultrasonic transducer 2-3 to produce ultrasonic 9 after amplifying, the frequency of the ultrasonic wave that present embodiment adopts It is 1MHz; after the ultrasound is focused by the focusing lens 2-4, it modulates the biological tissue simulation medium near the focal point, and when the laser beam passes through this area, it is also modulated due to the change of the parameters of the biological tissue there;

[0036] (3) Scattered laser light containing modulation information (such as light intensity changing at ultra...

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Abstract

The focussing ultrasonic modulation reflection type optical chromatographic imaging method utilizes the focussing ultrasonic technique to make modulation and tissue location of the laser injected into deep biological tissue, and uses optical technique to make high-sensitivity detection and real-time high-speed. Fourier transform to process signal, and can obtain the chromatogram of pathologic changed tissue region. The injection laser mand modulation ultrasonic wave are coaxially-retained, and its signal exciting device and receiving device adopt homoside reflection mode. Said optical chromatographic imaging equipment is formed from laser, optical polarization component, ultrasonic component, photo-electric conversion component, signal display and real-time rapid Fourier transform module and computer.

Description

technical field [0001] The invention relates to biomedical imaging technology, more precisely, a focused ultrasound modulation reflective optical tomography method. [0002] The invention also relates to a device for implementing the above optical tomography method. Background technique [0003] At present, widely used biomedical imaging diagnostic technologies, such as X-ray tomography (CT) and nuclear magnetic resonance imaging, etc., have certain damage to human tissues, and X-ray tomography devices and nuclear magnetic resonance equipment are expensive; although B-mode ultrasonic detection There is basically no harm to people, and the cost of the instrument is relatively low. However, due to the reflection imaging of the tissue interface, tomography cannot be realized, and the resolution is also low. For tissues in the body with simple structures, the best resolution is a few millimeters. And the resolution drops further when examining the moving organs. Although new t...

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Application Information

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IPC IPC(8): A61B6/00A61B8/00
Inventor 邢达傅洪波
Owner SOUTH CHINA NORMAL UNIVERSITY
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