784results about How to "Quantity maximization" patented technology

A method and device for treating a mammalian organism to obtain a desired local or systemic physiological or pharmacological effect is provided. The method includes administering a sustained release drug delivery system to a mammalian organism in need of such treatment at an area wherein release of an effective agent is desired and allowing the effective agent to pass through the device in a controlled manner. The device includes an inner core or reservoir including the effective agent, an impermeable tube which encloses portions of the reservoir, and a permeable member at an end of the tube.

Embodiments of this invention provide methods, systems, and apparatus for determining whether a fetal chromosomal aneuploidy exists from a biological sample obtained from a pregnant female. Nucleic acid molecules of the biological sample are sequenced, such that a fraction of the genome is sequenced. Respective amounts of a clinically-relevant chromosome and of background chromosomes are determined from results of the sequencing. A parameter derived from these amounts (e.g. a ratio) is compared to one or more cutoff values, thereby determining a classification of whether a fetal chromosomal aneuploidy exists.

Apparatus and methods are described for treatment of morbid obesity using minimally invasive techniques. The apparatus includes a system of components that may be used separately or in combination for effectively reducing stomach volume, bypassing a portion of the stomach and / or small intestines, reducing nutrient absorption in the stomach and / or small intestines and / or depositing minimally or undigested food farther than normal into the intestines, thereby stimulating intestinal responses. The components described include a gastric sleeve device, an intestinal sleeve device, and a combined gastrointestinal sleeve device.

The invention is directed toward a malleable bone putty and a flowable pastel composition for application to a bone defect site to promote new bone growth at the site which comprises a new bone growth inducing compound of partially demineralized lyophilized allograft bone material having a residual calcium content ranging from 4 to 8% dry weight. The bone powder has a particle size ranging from about 100 to about 800 microns and is mixed in a high molecular weight hydrogel carrier containing a sodium phosphate saline buffer, the hydrogel component of the carrier ranging from about 1.00 to 50% of the composition and having a molecular weight of about at least 700,000 Daltons. The composition has a pH between 6.8-7.4 contains about 25% to about 35% bone powder and can be additionally provided with BMP's.

Apparatus and methods are described for treatment of morbid obesity using minimally invasive techniques. The apparatus includes a system of components that may be used separately or in combination for effectively reducing stomach volume, bypassing a portion of the stomach and / or small intestines, reducing nutrient absorption in the stomach and / or small intestines and / or depositing minimally or undigested food farther than normal into the intestines, thereby stimulating intestinal responses. The components described include an artificial stoma device, a gastric sleeve device, an intestinal sleeve device and a combined gastrointestinal sleeve device.

The invention is directed toward an osteoimplant for application to a bone defect site to promote new bone growth at the site which comprises a new bone growth inducing composition of demineralized allograft bone material mixed with an aqueous phosphate buffered gelatin which when lyophilized to remove water from the composition cross links the gelatin to form a solid structure.

Passive balanced probes are disclosed for use with a signal analysis device. The probes are very low cost relative to typical commercially available probes and provide an extremely flat response over a frequency range of approximately 0 to at least 1.5 gigahertz. The probes include a probe body constructed primarily from conventional components, a first surface mount resistor electrically connected between a probe tip and a center conductor, and two surface mount resistors electrically connected and parallel between the center conductor and a conductive shield. The probes further include a coaxial cable for connection to an instrument combiner or other instrument connection device.

The invention is directed toward a formable bone composition for application to a bone defect site to promote new bone growth at the site which comprises a new bone growth inducing compound of demineralized lyophilized allograft bone particles. The particle size ranges from about 0.1 mm to about 1.0 cm and is mixed in a hydrogel carrier containing a sodium phosphate saline buffer, the hydrogel component of the carrier ranging from about 1.0 to 5.0% of the composition and a pH between 6.8–7.4 with one or more additives of a cellular material, growth factor, demineralized bone chips or mineralized bone chips.

An inductive power transfer system includes a number of controllable reactive components (3, 6, 12, 13, 16) that allow the resonant frequency of a primary and / or secondary resonant circuit to be controllably varied to thereby control power available to a load (10).

The invention is directed toward a malleable bone putty and a flowable gel composition for application to a bone defect site to promote new bone growth at the site which comprises a new bone growth inducing compound of demineralized lyophilized allograft bone powder. The bone powder has a particle size ranging from about 100 to about 850 microns and is mixed in a high molecular weight hydrogel carrier, the hydrogel component of the carrier ranging from about 0.3 to 3.0% of the composition and having a molecular weight of about at least 10,000 Daltons. The composition contains about 25% to about 40% bone powder and can be additionally provided with BMP's and a sodium phosphate buffer.

Session data is encoded in a tag-length-value format and encrypted using a modified encryption key. A session cookie is then formed by concatenating the length of the length of the secret, the length of the secret, the secret itself, and the encoded and encrypted configuration data. The session cookie is transmitted from a server computer to a client computer, where it is stored.

A biopsy device used to capture a tissue sample by placing the tissue under tension, thus allowing a greater sized sample with increased quality. The device uses a rotating cannula and stylet with a concave “sample notch.” The rotation of the stylet places the tissue under tension while the rotation of the cannula as it is fired severs the sample.

The present invention relates to a wind energy generating and storing system comprising methods and apparatuses for providing energy dedicated for immediate use and energy storage, to provide electrical power on an uninterrupted and continous basis, to locations remote from an electrical power grid. In a large application, the invention contemplates having a predetermined number of windmills dedicated for immediate use, and a predetermined number of windmills dedicated for energy storage, as compressed air energy in one or more high pressure tanks. A hybrid windmill having the ability to simultaneously switch between energy for immediate use and energy storage can also be provided.

A nozzle comprised of a thin, flexible membrane material having a plurality of pores is disclosed. In one embodiment, the pores have an unflexed exit aperture diameter in the range of about 0.5 to about 2 microns (preferably about 1 micron) and are positioned substantially uniformly in the material, preferably about 50 microns apart. The nozzle preferably has a conical or trumpet-shaped cross-section. In another aspect of the invention, the exit aperture of the nozzle is surrounded by an elevated area protruding above the substantially planar exit side of the membrane in order to prevent intrusion of liquid back into the nozzle. The nozzle can be used to form an aerosol containing a pharmaceutical composition from the exit side of the nozzle upon forcible application of the composition to the entrance side of the nozzle. This aerosol can be used to administer the pharmaceutical composition, for example, to the eye or to a selected portion of the respiratory tract. The nozzle is preferably a component of a container which holds a formulation of drug.

An auction system for providing an auction service via a communication network comprises an auction server machine and buying user terminals which are connected to the communication network; wherein the buying user terminals specify a single item or any combination of items for bidding when multiple items are sold as grouped items at the auction held by the auction server machine; and the auction server machine decides on successful bidders for bids made on a variety of combinations of the grouped items from the buying user terminals, such that the items composing the grouped items do not overlap to multiple bidders and the total price becomes maximal.

A method for the production of ethanol and a modified animal feed is provided. The method replaces the starch in known corn-based animal feed with biomass fiber treated to make it more digestible by animals. The process includes wherein the pericarp and germ are removed from the corn kernel and processed for by-products. The starch and protein are also removed and separated. The starch is then fermented and distilled to ethanol and stillage. The bioavailable modified animal feed comprises the pericarp and germ removed from corn kernels and optionally by-products of the pericarp and germ processing, and lignocellulosic materials. The modified animal feed may optionally include energy materials such as animal and vegetable fats, vegetable soapstocks, or glycerin, and combinations thereof.

A system provides a user with free Internet network access, in which an access control system sends video advertising files to a user who gains access to the Internet through a network connection that includes a viewer program that operates independently of the user's browser and e-mail programs. The viewer receives ads from the access control system and manages an ad pool that collects multiple video advertising files. Video advertising files are downloaded when the user is not actively using the bandwidth of the Internet connection to download Internet content of the user's choosing. The viewer program periodically opens a viewer window, which opens on top of any other open windows, and in which a video ad from the ad pool is displayed. When one or more video ads are finished, the viewer window is hidden or made an inactive window for a quiet interval. At the conclusion of the quiet interval, the viewer window is activated and the next ad in the ad pool is displayed. The viewer program cycles through existing ads in the ad pool until a new ad is received from the access server. The viewer program manages the ad pool such that the oldest ad is discarded when a new ad is received, and such that each ad is displayed or viewed in order of download for the average time it takes to download an ad in the ad pool. This ensures that ad viewing can continuously cycle through the ad pool with the minimum of repetition, and with no interruption to the user's Internet experience.

A hand-held power syringe. The power syringe includes a handle with pivotally connected first and second members. The first member is also pivotally connectable to a syringe barrel, while the second member is pivotally connectable to a syringe plunger. These three pivotal connections provide leverage for forcing high viscosity fluids into and out of a receptacle of the syringe barrel. One or both of the first and second members of the handle may be bent to facilitate a user's gripping and movement of the first and second handle members. The power syringe may be used in any suitable injection, infusion, or sample-obtaining application, including angiography and angioplasty.

A system for the production of a blood component composition is provided. The system includes a centrifuge having a blood reservoir for receiving and separating a blood sample into multiple components; a dispenser disposed outside of the centrifuge having a first collection chamber containing an activation agent and a second collection chamber containing one or more medicinal agents; means for removing a first portion at least one separated blood component from the centrifuge to the first container and a second portion to the second collection chamber, wherein the first collection chamber activates the first portion and stores the resulting clot and thrombin; a filter for separating the thrombin from the clot; and a nozzle for entraining and mixing the thrombin with the second portion containing the one or more medicinal components.

Some embodiments of the invention provide a single-select method and system for launching clinical information in multiple dashboards based on a selection of a single piece of clinical information (e.g., based on a cursor-click selection of a patient name in a patient list). In some embodiments, each launched dashboard is a single “flat” dashboard that cannot be “drilled down” to another dashboard. In other embodiments, each launched dashboard can be a drilldown dashboard, i.e., a dashboard that is several dashboards that are linked together so that a user can navigate between them by selecting items displayed in the dashboards (e.g., by traversing from a first dashboard to a second dashboard through a selection of an item in a window pane of the first dashboard). Accordingly, some embodiments use the single-select method of some embodiments in lieu of drill-down dashboards, while other embodiments use the single-select method in conjunction with drill-down dashboards.

A putter golf club that resists twisting by increasing the rotational inertia of the golf club to the maximum degree possible by distributing mass away from the center of mass of the putter, and thereby expands the sweet spot of the putter. Rotational inertia is maximized via use of a heel control wing and a toe control wing extending rearwardly and outwardly from a striking face of the putter as well as a tail rod extending perpendicularly from striking face. Further increase of rotational inertia is accomplished via s symmetrical recesses incorporated into heel and toe control wing.

A wind turbine includes a rotor having a hub and at least one blade having a torsionally rigid root, an inboard section, and an outboard section. The inboard section has a forward sweep relative to an elastic axis of the blade and the outboard section has an aft sweep.

A method for the production of ethanol and a modified animal feed is provided. The method replaces the starch in known corn-based animal feed with biomass fiber treated to make it more digestible by animals. The process includes wherein the pericarp and germ are removed from the corn kernel and processed for by-products. The starch and protein are also removed and separated. The starch is then fermented and distilled to ethanol and stillage. The bioavailable modified animal feed comprises the pericarp and germ removed from corn kernels and optionally by-products of the pericarp and germ processing, and lignocellulosic materials. The modified animal feed may optionally include energy materials such as animal and vegetable fats, vegetable soapstocks, or glycerin, and combinations thereof.

The invention relates to sustained release implants and to methods for treating eyes, particularly the eyes of mammals having eye disorders or diseases. By using the implants and methods described herein, the delivery of the one or more bioactive agents can be localized at a desired treatment site, particularly the choroid and the retina.

Provided are apparatuses and methods for padding a series of real-time service time-slice bursts with related non-real-time service data in a digital broadcast transmission system. Real-time services (e.g., streaming video) are formed into a series of bursts or slots as a single frame. Available capacity within each slot of the frame is filled using related non-real-time service data (e.g., a file download). Receivers may receive individual bursts from within the frame and / or may receive the entire frame in order to receive the related non-real-time service data.

An automatic truck unloader for unloading / unpacking product, such as boxes or cases, from trailers and containers is disclosed. In one embodiment, a mobile base structure provides a support framework for a drive subassembly, conveyance subassembly, an industrial robot, a distance measurement subassembly, and a control subassembly. Under the operation of the control subassembly, an industrial robot having a suction cup-based gripper arm selectively removes boxes from the trailer and places the boxes on a powered transportation path. The control subassembly coordinates the selective articulated movement of the industrial robot and the activation of the drive subassembly based upon the distance measurement subassembly detecting objects, including boxes, within a detection space, and dimensions of the trailer provided to the control subassembly.