The invention discloses a bone-strengthening
drug quality detection method, and belongs to the
drug quality detection technical field. The adopted technical scheme comprises that the bone-strengthening
drug is made into capsules by an artificial tiger bone
powder and auxiliary materials, and the quality detection method includes the following determining steps: 1) after the bone-strengthening drug is hydrolyzed, determining the content of
total amino acids in the samples, wherein each
capsule contains not less than 65 mg of the
total amino acids; and 2) determining the content of
total calcium in the bone-strengthening drug by adopting atomic absorption
spectrophotometry, wherein each
capsule contains not less than 55 mg of
calcium. The determination method for determining the content of the
total amino acids in the preparation by adopting
microwave hydrolysis and automatic online derivation, using a full-automatic
amino acid analyzer or adopting traditional
hydrolysis and PITC
derivation method and using
high performance liquid chromatography is established, the determination method for determining the content of
calcium in the samples by adopting the atomic absorption
spectrophotometry is increased, the accuracy and advancement of the quality detection method is ensured, and the product quality of Jintiange capsules can be effectively controlled.