184 results about "Methyl formate" patented technology

The invention discloses an anti-yellowing PVB (Polyvinyl Butyral) adhesive for laminated glass and a preparation method thereof, and relates to the technical field of adhesives. The yellowing-resistant PVB glue for the laminated glass has the advantages that the yellowing resistance is high; the modified PVB / nano silicon dioxide composite material is prepared from the following raw materials in parts by weight: 55 to 65 parts of modified PVB resin, 4 to 6 parts of modified nano silicon dioxide, 15 to 20 parts of dioctyl adipate, 0.5 to 1 part of a compound antioxidant, 0.3 to 0.8 part of an ultraviolet absorbent UV-327, 0.2 to 0.5 part of a silane coupling agent KH-560, 0.3 to 0.6 part of ethylene bis stearamide, 0.1 to 0.3 part of 2-benzimidazole methyl carbamate, 3 to 5 parts of tris (1-chloro-2-propyl) phosphate and 0.1 to 0.3 part of nano titanium dioxide. 5 to 8 parts of isopropanol; 0.8 to 1.2 parts of polycarbodiimide. The special modified PVB resin and the nano silicon dioxide are matched with the auxiliary agents such as the compound antioxidant, the anti-yellowing performance of the PVB glue for the laminated glass is remarkably improved through precise process preparation, the components have a synergistic effect, the process is controllable, the product performance is stable, and the cohesiveness is good.

The invention relates to the technical field of catalyst materials and discloses a low-temperature catalyst for preparing methyl formate through methanol dehydrogenation as well as a preparation method and application of the low-temperature catalyst. The low-temperature catalyst comprises Cu nano-particles and a composite metal oxide attached outside the Cu nano-particles, the composite metal oxide comprises CaO and CeO2. When the low-temperature catalyst disclosed by the invention is used for catalyzing methanol dehydrogenation to prepare methyl formate, the reaction can be realized at a relatively low temperature, and the low-temperature catalyst has relatively high methyl formate selectivity.

The present application relates to a kind of chalcone amide alpha-glucosidase inhibitors and its preparation and application, the inhibitor structural formula is: preparation method specifically is (1) after 2-hydroxyacetophenone, sodium hydroxide and methyl p-formylbenzoate are reacted, intermediate in formula (a) is obtained after post-processing;(2) intermediate in formula (a) is dissolved in organic solvent and potassium hydroxide is reacted, after reaction, intermediate in formula (b) is obtained after post-processing;(3) intermediate in formula (b) and substituted aniline are dissolved in organic solvent, after reaction, the inhibitor shown in formula (c) is obtained after post-processing.Compared with prior art, the compound of the present application is novel, and experiments show that it has good alpha-glucosidase inhibitory activity, and can be used for preparing alpha-glucosidase activity inhibiting drug.

The invention relates to the technical field of organic synthesis, and particularly provides a thiophene-containing tetraarylethene compound as well as a preparation method and application thereof. According to the invention, two phenyl groups of tetraphenylethylene are replaced by methyl formate thiophene groups, and the substituted tetraarylethylene compound has more remarkable photochromic and mechanochromic dual functions through the interaction of a specific substituent group at the position 2 of thiophene and a large conjugated group formed by four aromatic rings; and light-operated double-color display in a polymer mechanism can be realized. The mechanochromism of the compound does not depend on ultraviolet light, when the compound is subjected to mechanical force, the molecular accumulation mode and conjugate planarity are changed, and the color change can be directly observed by naked eyes. Different from traditional tetraphenyl ethylene force-induced discoloration recessive fluorescence change, the dominant color change can be used in the fields of visual stress monitoring, anti-counterfeiting marks, inkless writing materials, safe ink and the like in ultraviolet-free environments (such as indoor and closed spaces), and the application prospect is wide.

The invention relates to the field of organic synthesis, in particular to a synthetic method of (2R, 4S)-N-BOC-4-hydroxypiperidine-2-methyl formate. The synthesis method of (2R, 4S)-N-BOC-4-hydroxypiperidine-2-methyl formate comprises the following steps: mixing a material A, a material B, potassium carbonate, sodium iodide and a solvent, and reacting to obtain a material C; mixing the material C, the material D, triethylamine and a solvent, and reacting to obtain a material E; mixing the material E, ammonia water and a solvent, and reacting to obtain a material F; and mixing the material F, di-tert-butyl dicarbonate, a palladium carbon catalyst and a solvent, and carrying out a reaction to obtain the (2R, 4S)-N-BOC-4-hydroxypiperidine-2-methyl formate. The process route is easy to operate and has no special dangerous reaction. Reaction materials are cheap and easy to obtain, and the prepared product is high in purity.

The present invention provides a blowing agent for producing extruded polystyrene foam having low lambda over time and low foam density. [Solution] The foaming agent comprises (a) a first co-foaming agent consisting of (a) about 50% to about 70% by weight of HFO and / or HFCO having three or four carbon atoms, (b) about 2% to about 15% by weight of methyl formate, (c) a second co-foaming agent consisting of about 20% to about 30% by weight of dimethyl ether, isobutane and combinations thereof, and (d) a third co-foaming agent consisting of about 2% to about 25% by weight of carbon dioxide, acetone and combinations thereof.

The invention discloses (E)-1, 4-diether olefin and a preparation method thereof, and the (E)-1, 4-diether olefin is obtained by using 1, 3-diene as a raw material and carrying out electrochemical reaction in the presence of an electrolyte and a solvent, wherein the 1, 2, 4-trimethyl-1, 3- The structural formula of the 1, 3-diene is as follows: R1 is phenyl, p-fluorophenyl, p-chlorphenyl, p-bromophenyl, p-methylphenyl, p-methoxyphenyl, p-trifluoromethylphenyl, p-trifluoromethoxyphenyl, p-acetoxyphenyl, p-methyl formate phenyl, p-cyanophenyl, p-pinacol borate phenyl, p-phenylphenyl, o-oxybenzyl phenyl and o-methoxyphenyl; r1 is one of 1, 2-naphthyl; the solvent is a mixed solvent containing methanol. The preparation method of (E)-1, 4-diether olefin has high E-selectivity and 1, 4-selectivity, and an electro-catalysis mode is adopted, so that the use of a stoichiometric toxic, expensive or dangerous oxidant is avoided.

The present application belongs to the technical field of fermented fruit juice, and particularly relates to a method for preparing high-quality probiotic fermented strawberry juice based on magnetic field assistance. The present application first uses Lactobacillus plantarum CTCF-LP-1 to perform static fermentation on the strawberry juice to be fermented in a fermentation device for more than 24 hours, and then places the fermentation device in a static magnetic field. The static magnetic field reduces the generation of organic acid components by Lactobacillus plantarum during the fermentation process of the strawberry juice, reduces the acidity, and improves the fermentation quality of the strawberry juice. The magnetic field strength of the static magnetic field is 1.0-2.5 mT, and the fermentation time in the static magnetic field is 0.5-1.5 h. After the static fermentation and the magnetic field treatment, the content of malic acid, isocitric acid, glutaconic acid and other organic acid components in the fermented strawberry juice is significantly reduced, while the content of alcohol and ester components such as n-octanol, 2-phenylethanol, methyl benzoate, 3-hexyl hexanoate and butyl valerate is increased, the types of aroma components are more abundant, and the taste and quality of the strawberry juice are significantly improved.

The application discloses a preparation method of 2-pyrimidine methyl formate. The application provides a preparation method of 2-pyrimidine methyl formate, which comprises the following steps: step (1), 2-cyanopyrimidine and methanol are reacted in the presence of water and acid; and step (2), a dehydrating agent is added into the reaction solution in step (1) to prepare 2-pyrimidine methyl formate. The preparation method has one or more advantages of simple operation, high yield, high purity, low cost and suitability for industrial production.

The invention relates to the technical field of electrolyte, in particular to electrolyte for a lithium ion capacitor and a preparation method of the electrolyte. The electrolyte for the lithium ion capacitor comprises the following preparation raw materials: 50 to 55 parts of ethylene carbonate, 30 to 35 parts of methyl cyclohexylformate, 8 to 10 parts of siloxane solvent, 20 to 25 parts of lithium salt, 0.5 to 0.8 part of bis (trifluoromethanesulfonyl) imine, 2 to 5 parts of quaternary ammonium salt and 2 to 2.5 parts of functional additive. The electrolyte for the lithium ion capacitor prepared by the invention has excellent low-temperature performance, high power characteristic, wide temperature range adaptability, long cycle life and safety by optimizing the solvent system, the lithium salt ratio and the synergistic effect of the multifunctional additive, and is suitable for the high-performance lithium ion capacitor.

The invention relates to the technical field of dispergators, and discloses a dispergator and a preparation method and application thereof, the dispergator comprises the following components by mass: 50-100 parts of a penetrant, 50-100 parts of a swelling agent, 10-20 parts of a dispersant, 0.1-1 part of a surfactant A, 0.1-1 part of a surfactant B, and 1-5 parts of a catalyst; the penetrant is composed of methyl formate, ethanol, ethyl acetate, acetone and dichloromethane; the swelling agent is prepared from N-methyl pyrrolidone, dimethyl sulfoxide, tetrahydrofuran, N, N-dimethyl formamide, N, N-dimethyl acetamide, hexamethylphosphoric triamide and xylene. By compounding the penetrating agent, the swelling agent, the dispersing agent, the surfactant and the catalyst, the obtained dispergator can decompose an epoxy resin adhesive at a higher dispergation speed in the process of disassembling the retired battery pack.

The invention relates to the field of organic synthesis, in particular to a synthetic method of (2R, 4S)-N-BOC-4-hydroxypiperidine-2-methyl formate. The synthesis method of (2R, 4S)-N-BOC-4-hydroxypiperidine-2-methyl formate comprises the following steps: mixing a material A, a material B, potassium carbonate, sodium iodide and a solvent, and reacting to obtain a material C; mixing the material C, the material D, triethylamine and a solvent, and reacting to obtain a material E; mixing the material E, ammonia water and a solvent, and reacting to obtain a material F; and mixing the material F, di-tert-butyl dicarbonate, a palladium carbon catalyst and a solvent, and carrying out a reaction to obtain the (2R, 4S)-N-BOC-4-hydroxypiperidine-2-methyl formate. The process route is easy to operate and has no special dangerous reaction. Reaction materials are cheap and easy to obtain, and the prepared product is high in purity.

The objective is to provide a fragrance composition that has high reproducibility of the fragrance of forsythia flowers and excellent palatability. [Solution] The forsythia flower fragrance composition comprises (A) methyl salicylate and / or ethyl salicylate, (B) methyl benzoate and / or ethyl benzoate, and (C) linalool and / or limonene, wherein the total content of component (A) and component (B) is 50 to 90% by mass, and the mass ratio (A / B) is 1 to 10.

The invention relates to the technical field of organic chemical synthesis, in particular to a catalyst and a process for preparing methyl glycolate and co-producing methyl formate through methanol dehydrogenation coupling oxalate hydrogenation, which comprises the following steps: S1) providing a coal-to-ethylene glycol device which comprises a methanol rectifying tower, a DMO synthesis system, a DMO refining system, a DMO hydrogenation reactor and a condensing system; s2) taking methanol extracted from a methanol rectifying tower as a raw material, and carrying out anaerobic dehydrogenation reaction under the action of the catalyst in any one of claims 1-2 or the catalyst prepared by the preparation method in claim 3 to obtain methyl formate, H2 and CO; and S3) by taking dimethyl oxalate extracted from a DMO refining system as a raw material, carrying out hydrogenation reaction under the action of the catalyst in any one of claims 4-5 or the catalyst prepared by the preparation method in claim 6 to obtain methyl glycolate and methanol.

The invention discloses a dithiocarbamate nickel (II) complex as well as a preparation method and application thereof, the chemical formula of the nickel (II) complex is [NiIILCl], and L is (E)-2-(phenyl (pyridine-2-yl) methylene) hydrazino methyl dithioformate. The nickel (II) complex is mild in synthesis condition and high in target yield. In-vitro MTT activity evaluation proves that the introduction of copper ions has a synergistic effect on the anticancer activity of the nickel (II) complex, so that the activity of the nickel (II) complex is improved from a micromole level to a nanomole level, and the amplification is as high as 200 times or more. Cell scratch experiments prove that the nickel (II) complex and copper (II) ions are combined for use, so that the migration resistance is achieved. A nickel (II) complex and copper ion combination strategy provided by the invention not only has a direct killing effect on cancer cells, but also can effectively inhibit the migration ability of the cancer cells, and shows huge application potential in the field of cancer treatment.

The invention relates to the technical field of industrial methyl formate preparation, and particularly discloses carbon monoxide gas pretreatment and impurity removal equipment for industrial methyl formate preparation, the side face of a tower body is fixedly connected with a feeding component, the top of the tower body is fixedly connected with an exhaust port, the inner side of the tower body is fixedly connected with a spraying component, and the spraying component is fixedly connected with a gas outlet. The side face of the spraying part is fixedly connected with a water pipe. The carbon monoxide gas pretreatment and impurity removal equipment for industrial methyl formate preparation is provided with a contact mechanism, an arc-shaped contact plate is attached to the inner wall for cleaning, impurities are prevented from being attached and gathered on the tower body, the stable spraying and impurity removal efficiency is guaranteed, a second spring buffer structure can resolve overlarge extrusion force, the contact plate is prevented from rubbing the inner wall of the tower body, and the service life of the tower body is prolonged. The service life of equipment is prolonged, the cleaning range is complemented in the reset process of the triangular scraping plate, the blind area problem caused when a single contact plate moves downwards is solved, and inner wall cleaning under all working conditions is achieved.

Described herein are processes for the synthesis of P2X3 antagonists, wherein the P2X3 antagonist is methyl (S)-2-((2-(2,6-difluoro-4-(methylcarbamoyl)phenyl)-7-methylimidazo[1,2-a]pyridin-3-yl)methyl)morpholine-4-carboxylate (Compound 1), or a pharmaceutically acceptable salt or co-crystal thereof.

This invention relates to a heteropolyacid catalyst for the condensation of formaldehyde and methyl formate to methyl glycolate, the preparation method of which includes the following steps: (1) loading the active component and (2) overflow hydrogen reduction. This invention uses common silica as a support and employs a co-impregnation method to load the active component to prepare the catalyst, under mild conditions and with a stable and controllable process. By doping with an appropriate amount of metal, overflow hydrogen is induced to reduce some coordinating atoms in the heteropolyacid as basic sites, which synergistically interact with the strongly acidic sites of the heteropolyacid to promote the cross-condensation of formaldehyde and methyl formate, thereby improving the reaction activity and selectivity. The prepared catalyst has advantages such as low reaction temperature, high activity, and good selectivity.

The present application relates to the technical field of tail gas treatment of pesticide compound production, and particularly relates to a tail gas absorption system in cyanamide methyl formate production process, comprising: a tail gas collecting pipeline, a pretreatment unit, a deep purification unit and a detection device; wherein the pretreatment unit comprises a dust removal tower for cooling and dedusting the tail gas; the deep purification unit comprises an absorption tower made of stainless steel, PPH or glass steel, which is used for purifying the tail gas and treating toxic and harmful substances in the waste gas; the detection device is used for real-time monitoring of tail gas emission indexes to ensure standard emission. The technical scheme can quickly and effectively adsorb and purify the tail gas generated in the cyanamide methyl formate production process, has high adsorption performance, and also has large adsorption capacity and excellent selectivity.

The application discloses an organic complex of different metals LTG-RuCe and a preparation method and application thereof, and belongs to the technical field of catalysts. The preparation method of the organic complex of different metals LTG-RuCe comprises the following steps: synthesizing a ligand HL by using methyl formylbenzoate, 2-acetylpyridine, ethanol, potassium hydroxide and ammonia water; synthesizing a ligand [Ru(HL)2]·(PF6)2 by using trichlororuthenium, the ligand HL, methanol, potassium hydroxide and HPF6; and synthesizing the organic complex of different metals LTG-RuCe by using cerium nitrate hexahydrate, the ligand [Ru(HL)2]·(PF6)2 and N,N-dimethylformamide. The organic complex of different metals LTG-RuCe synthesized by the application has high CO2 catalytic activity, good repeatability and a structure which is not easy to collapse; and the method for preparing the organic complex of different metals provided by the application has high yield and strong operability.

Described herein are two processes for the preparation of methyl (5)-2-((2-(2,6-difLuoro-4-(methylcarbamol)phenyl)-7-methylimidaz[1,2-a]pyridine-3-yl)methyl)morpholine-4-carboxylate, a P2X3 antagonist, in a stepwise manner and chemical intermediates used in the synthetic processes.

The application relates to a synthesis method of a compound 4-bromo-5-(trifluoromethyl) thiophene-2-carboxylic acid methyl ester, characterized in that the synthesis method takes 4,5-dibromothiophene-2-methyl ester as raw material, takes cuprous halide as a catalyst, takes diphenyl(trifluoromethyl)sulfonium triflate as a trifluoromethyl reagent, and reacts at a selected temperature, so that 4-bromo-5-(trifluoromethyl) thiophene-2-carboxylic acid methyl ester is generated with high selectivity. The method is high in atom economy, simple to operate, high in regioselectivity, relatively mild in reaction conditions, and very suitable for industrial scale production.

The invention discloses a method for preparing polyoxymethylene dimethyl ether with low polymerization degree by using a water-containing formaldehyde system, and belongs to the technical field of methanol-based clean fuel and environment-friendly solvent preparation. According to the method, water-containing formaldehyde with the mass concentration of 55%-85% and methylal with the mass concentration of 92%-99% serve as raw materials, DMM2-4 is synthesized in a fixed bed reactor under the catalysis of strong acid cation exchange resin, after dimethyl ether and methyl formate by-products are removed from reaction products through flash evaporation, unreacted formaldehyde, methyl alcohol and formic acid are separated through multi-stage water extraction, and DMM2-4 is obtained. Returning the water phase to the methylal preparation unit for cyclic conversion; and carrying out multi-tower rectification and finishing on the organic phase to respectively obtain high-purity DMM2 and DMM3-4 products. Water is adopted as an extracting agent, organic pollution is avoided, the total utilization rate of formaldehyde is larger than or equal to 97%, the product purity reaches up to 98% or above, acidity is low, the product can be directly used as a diesel additive or an environment-friendly solvent, and the advantages of being low in raw material cost, environmentally friendly in process, high in product purity and the like are achieved.

The present application relates to the technical field of polyurethane coating, in particular to a waterproof polyurethane composite coating and a preparation process thereof. The preparation process of the waterproof polyurethane composite coating comprises the following steps: preparing quercetin grafted composite filler, preparing modified isophorone diisocyanate solution and preparing polyurethane composite coating. In the present application, polybutylene adipate, dimethylol butyric acid and dibutyltin dilaurate are mixed with the modified isophorone diisocyanate solution to carry out pre-polymerization, then 2-hydroxy-5-substituted long-chain fatty acyloxy methyl benzoate is added to carry out reaction, long-chain fatty acyloxy and methyl benzoate structure are introduced into the polyurethane molecular chain, trimethylolpropane is added to carry out crosslinking reaction, finally, 1,4-butanediol is added as a chain extender to react with the remaining -NCO to prepare the polyurethane composite coating, which can effectively improve the water resistance and adhesion of the polyurethane composite coating.

According to the method and system for preparing formic acid by catalyzing hydrolysis of methyl formate through the ionic liquid, in the system and method, the reversible reaction of hydrolysis of methyl formate can be prevented through the basic ionic liquid, hydrolysis of methyl formate into methyl alcohol and formic acid is promoted, and the conversion rate of methyl formate is increased; meanwhile, the re-esterification reaction of the hydrolysis product formic acid and methanol can be inhibited, so that the concentration of formic acid in the hydrolysis product is improved, the energy consumption during formic acid concentration is reduced, and more favorable conditions are provided for subsequent formic acid concentration. In addition, the alkaline ionic liquid can break azeotropy of formic acid and water so as to realize efficient hydrolysis and product separation. In addition, through reasonable backflow and cyclic utilization of materials among the towers, unnecessary multiple rectification separation is avoided, energy consumption is reduced, and production efficiency is improved.

This invention relates to the field of seawater desalination technology, specifically to a high-permeability and selective reverse osmosis membrane and its preparation method. The high-permeability and selective reverse osmosis membrane is obtained by sequentially immersing a porous support layer in an aqueous solution and an oil solution for interfacial polymerization, thereby forming a desalination layer on the surface of the porous support layer. This invention increases the compatibility of the water / oil phases by adding N-methylpyrrolidone to the aqueous phase and methyl benzoate to the oil phase, thereby reducing the surface tension of the two phase solutions, promoting the diffusion of amine monomers into the organic phase, and altering the surface morphology and polymer chain aggregation state of the separation layer. This results in a higher roughness and cross-linking degree of the desalination layer, and improved permeability and selectivity.

The invention relates to the field of high-barrier PET composite materials, in particular to a high-barrier PET composite material as well as a preparation method and application thereof. The high-barrier PET composite material is prepared from the following raw materials in parts by mass: 80 to 90 parts of polyethylene glycol terephthalate, 6 to 8 parts of mushroom nano chitin compound, 1 to 2 parts of chain extender and 1 to 2 parts of antioxidant. According to the preparation method, mushroom nano chitin (ChNF) is utilized, surface modification is carried out through 3, 4-dihydro-2H-1, 4-benzoxazine-7-methyl formate (BZ-M), and nano diamond is anchored on the surface of ChNF in situ; and in the subsequent melt blending process, micro-crosslinking with a PET molecular chain is continued, so that the multiple barrier properties of oxygen barrier property, water vapor barrier property, ultraviolet barrier property and bacteria barrier property of the PET composite material are improved under the condition that the mechanical property and light transmittance are maintained.

The present invention relates to a salt and crystal form of an AT2R agonist and use thereof in pharmaceutics, and specifically relates to a salt and crystal form of methyl ((4-fluoro-5-isobutyl-3-(4-((2-(trifluoromethyl)-1H-imidazol-1-yl)methyl)phenyl)thiophen-2-yl)sulfonyl)carbamate (a compound represented by formula (I)) and use thereof in pharmaceutics.

The present application relates to a kind of aryl carboxylate compounds and its preparation method, preparation method includes the following steps: S1, under inert atmosphere, chloroformate or its derivative, aryl iodine, ligand, reducing agent, additive and catalyst are dissolved in solvent, obtain the reaction body solution;S2, the reaction body solution obtained in S1 step is stirred, obtain the aryl carboxylate compound of structural general formula as shown in III, wherein, R 1 Group is selected from H, 4-trifluoromethyl, 4-methoxy, 4-methyl formate in any one of methyl group, R 2 It is selected from 4-trifluoromethyl, 4-acetyl, 4-methyl formate in any one of methyl group.Compared with prior art, the present application uses chloroformate or its derivative, aryl iodine as substrate, aryl carboxylate compound is prepared, reaction condition is mild and substrate is widely adaptable, yield is as high as 80%.And raw material cost is low and easy to obtain, preparation condition is simple and also easy to realize.

The present invention discloses a flotation collector, a preparation method, and an application thereof, and relates to the field of mineral processing technology. The flotation collector comprises carbonized methyl carbamate, zinc diethyldithiocarbamate, butyl octanol, and sulfate in a mass ratio of (3-6): (1-12): (2-3): (3-8). During the flotation treatment of cassiterite ore, the composite flotation agent prepared thereby reduces the loss of easily muddied fine and micro-grained cassiterite in tailings after one roughing, three scavenging, and three cleaning steps. The agent accurately adsorbs and reduces the cassiterite content in the cassiterite ore, achieves efficient recovery of fine and micro-grained cassiterite, improves the effective recovery of cassiterite, and significantly improves the tin grade and recovery rate in the tin concentrate.