51 results about "Liquid liquid partition" patented technology

The invention relates to a detection method of determining 16 types of photoinitiators in a paper printing and packaging material, which is used for determining residual amounts of the 16 types of photoinitiators of 2-hodroxy-2-methyl-1-phenylacetone, mehtyl phenylglyoxylate, benzophenone and the like and is characterized by comprising the following concrete steps of: a, sample pretreatment; b, preparation of a standard work solution; c, instrumental analysis; and d, result calculation. Compared with the prior art, through sample pretreatment and optimization of instrumental analysis conditions, the detection method has the advantages that efficiency is high, the 16 kinds of photoinitiators can be simultaneously analyzed and determined within 25m; and printing ink impurities in a sample extraction solution can be better removed in a liquid-liquid distribution impurity removal mode adopted in the sample pretreatment process, so that cost is low, consumption is little, efficiency is high, and sensitivity is high; and in addition, the detection method also has the advantages of high accuracy and good repeatability.

The present invention generally provides systems and methods for the detection, identification, or characterization of differences between properties or behavior of corresponding species in two or more mixtures comprised of molecules, including biomolecules and / or molecules able to interact with biomolecules, using techniques such as partitioning. The experimental conditions established as distinguishing between the mixtures of the molecules using the systems and methods of the invention can also be used, in some cases, for further fractionation and / or characterization of the biomolecules and / or other molecules, using techniques such as single-step or multiple-step extraction, and / or by liquid-liquid partition chromatography. The methods could also be used for discovering and identifying markers associated with specific diagnostics, and can be used for screening for such markers once discovered and identified during diagnostics screening.

The invention discloses a novel process for extracting and separating tea phenol, which comprises the steps of extracting, liquid-liquid partition chromatography, and column chromatography integrated separation or the steps of extracting, liquid-liquid partition chromatography, and concentration integrated separation. The process comprises the following steps of: firstly, mixing water and tea at the mass ratio of between 0.2 and 1 to 1 uniformly, using extractant to extract the solution to obtain extraction liquid; then performing column chromatography or concentration drying to obtain tea phenol products with various specifications. During the extraction process, water-soluble impurities such as tea polysaccharide are retained in the tea and no tea polysaccharide waste water is produced. The tea polysaccharide, protein, fibrin, microelements and other compositions are retained in dried tea dregs after extraction, which can be used as good feed additives. The process can adopt integrated separation so as to improve the stability and the degree of automation greatly and reduce the number of workers and the labor intensity.

A liquid collection and distribution device is provided to support a bed of packing material and to collect liquid exiting the bed and redistribute it to an underlying bed of packing material with improved compositional and volumetric flow uniformity. The liquid collection and distribution device includes a liquid collector, a liquid distributor, and a lattice-type framework positioned between and supporting the liquid collector and the liquid distributor. In addition to supporting the liquid collector and liquid distributor, the framework has internal fluid passages that convey the liquid from the liquid collector to the liquid distributor while shielding the liquid from ascend vapor or gas flow.

A liquid dispensing nozzle having an opening, a removable cap, a residual liquid evaporation path between the opening and the exterior of the nozzle, an element for blocking the evaporation path, mobile in the cap between a blocking position and a position opening the evaporation path, the cap including an exterior envelope and an interior envelope that are coaxial, and mobile relative to one another in an axial direction between: a storage configuration; a configuration for unscrewing the cap when a bearing force exerted on the cap has an intensity greater than a predetermined threshold; a safety configuration if a bearing force exerted on the cap has an intensity lower than the predetermined threshold or if no bearing force is exerted on the cap, the blocking element being configured to be driven by the movement of the exterior envelope to pass from the blocking position to the opening position.

The invention relates to the technical field of detection of ingredients in liquid, in particular to an extraction structure and a liquid pretreatment device. The extraction structure comprises a cavity and a first pore passage, wherein a first filtering sheet, an extraction agent layer and a porous filtering sheet are sequentially arranged inside the cavity; an expanding agent is arranged inside the first filtering sheet, so that the filtering sheet capable of realizing sealing when meeting water is formed; the water solution passing can be prevented; the processes of liquid-liquid distribution and solid phase extraction can be realized in one step. The liquid pretreatment device using the extraction structure comprises a storage tank and a transferring device, wherein a filtering membrane used for filtering and support is arranged between the transferring device and the extraction structure; an organic solvent is filtered for many times, so that the detecting result of the ingredients of the collected organic solvent is more accurate; all steps of liquid-liquid distribution extraction, solid-phase extraction purification, microfiltration membrane filtering and transferring of liquid samples containing ingredients to be detected of the ingredients to be detected of the liquid samples can be realized in one step.

The invention discloses an ultrasonic assistant liquid-liquid spray extraction method. A liquid sample is pressed into an extraction container containing organic solvent in an atomization mode, meanwhile, the extraction container is soaked into an ultrasonic generator, so that the liquid sample and the organic solvent form turbulent flow, then the liquid sample contacts with the organic solvent in a smaller drop form, and the target compound in the sample is rapidly transferred into an organic phase to achieve fast extraction separation. Micromolecules in the atomized liquid sample are beneficial to improving the contact area with the organic solvent to quickly achieve liquid-liquid partition equilibrium; and the assistance of the ultrasonic generator enables the sample in the smaller drop form to contact with extracting agent, thereby the extraction efficiency is improved. The invention can separate and collect the liquid sample and has the advantages of time and labor saving, small dosage of solvent, easy operation, being applicable to large-capacity sample analysis, easy realization of semi-automation, and the like.

The invention relates to a detection method for simultaneously measuring the residue of chlordimeform and 4-chloro-2-methylaniline as the metabolite thereof in royal jelly, in particular to a detection method for measuring the residue of chlordimeform and 4-chloro-2-methylaniline as the metabolite thereof in the royal jelly by the gas chromatography-mass spectrometry (GC-MS). The method comprises the following steps: precipitating protein by a trichloroacetic acid solution; then, adjusting the pH value until the solution is alkaline; further purifying the solution by the liquid-liquid partition using acetonitrile / n-hexane; and measuring the residue by the GC-MS. The residue of chlordimeform and 4-chloro-2-methylaniline as the metabolite thereof in the solution to be measured can be measured in a way that chlordimeform and 4-chloro-2-methylaniline as the metabolite thereof coexist without conversion, therefore, the invention has the characteristics that the method is accurate, sensitive and simple.

The invention belongs to the field of natural organic chemistry, and relates to a method for purifying aloe polysaccharides, particularly a preparation method for enriching and purifying aloe polysaccharides in aloe by a high-speed countercurrent chromatography separation process. The method is characterized by purifying natural plant aloe leaching liquor twice by a high-speed countercurrent chromatography separation process to obtain aloe polysaccharides of which the purity is higher than 95%. The method is suitable for preparing high-purity aloe polysaccharides from natural plants containing aloe polysaccharides and extracts of the natural plants. The method is suitable for preparing aloe polysaccharides by separating with various types of countercurrent chromatographs, and the aloe polysaccharides prepared by the high-speed countercurrent chromatography process can be continuously, efficiently and quickly separated by liquid-liquid partition chromatography; and thus, the method has the characteristics of great separation amount, no sample loss, high recovery rate, mild separation environment, solvent saving and the like.

The invention belongs to the filed of natural organic chemistry and relates to a method for purifying agrimonine, in particular to a method for gathering and purifying the agrimonine in agrimony by utilizing high-speed counter current chromatography. The method is characterized in that leaching liquor of natural plant agrimony is purified twice by utilizing the high-speed counter current chromatography, thus obtaining the agrimonine with the purity of 98 percent. The method is suitable for preparing the high-purity agrimonine by adopting various natural plants and extracts of the natural plants containing the agrimonine as the main materials. The method is suitable for separating and preparing the agrimonine by adopting a counter current chromatograph of various types, and the method for preparing the agrimonine by utilizing the high-speed counter current chromatography can carry out continuous, efficient and rapid liquid-liquid partition chromatographic separation and has the advantages of large separation amount, no sample loss, high recovery rate, mild separation environment, saving solvent and the like.

The invention discloses a residue detection method for quinclorac in tobacco leaf and tobacco planting soil, belonging to the technical field of physical and chemical detection of residue of a paddy field herbicide. The residue detection method for the quinclorac in the tobacco leaf and the soil is researched by using high-performance liquid chromatography. The tobacco leaf and the tobacco planting soil are subjected to extraction by using 0.05 mol / L sodium hydroxide solution, liquid-liquid partition by using ethyl acetate and are purified by using a graphitized carbon and florisil mixed solid-phase extraction small column. When the addition level in the tobacco leaf and the soil is 0.05-2.00 mg / L, the average recovery rates of the tobacco leaf and the soil are 79.4-94.9 percent and 92.9-108.2 percent respectively, and the relative standard deviations are 8.1-12.9 percent and 5.5-9.6 percent respectively. The method has the advantages of easy, convenient and fast pretreatment method, low cost and high accuracy and precision, and can be used for providing reference for residue detection and fate research of the quinclorac in the tobacco leaf and the soil in a paddy-tobacco crop rotation system.

The invention relates to a liquid distributor with two stages of runners for a chromatographic column. The liquid distributor is provided with a main distribution disc, wherein a plurality of radial launders distributed along the circumference are formed in the surface of one side of the main distribution disc, an annular axial through hole communicated with the launders is formed in the middle of the main distribution disc, the longitudinal fracture surfaces of one sections, from the near edge of the main distribution disc to the axial through hole, of the launders are in tilted curve shapes, and the longitudinal fracture surfaces of one sections, from the axial through hole to the main distribution disc, of the launders are in downward-inclined linear shapes; a second-stage distribution disc is arranged on the other side of the main distribution disc, an annular runner is formed between the second-stage distribution disc and the main distribution disc, a central hole and a plurality of radial runners are formed in the second-stage distribution disc, the radial runners are communicated with the annular runner and the central hole, and a liquid outlet or inlet pipe is arranged on the second-stage distribution disc. According to the liquid distributor with two stages of runners, the longest flowing distances of liquid in the launders can be shortened, and the distribution uniformity and chromatography efficiency of the liquid are improved.

The invention provides an effective part of perilla leaf resisting hyperuricemia and a preparation method and application thereof. The effective part takes the perilla leaf as a raw material, and is prepared by the steps of extracting with water, concentrating, ethanol precipitation, reducing pressure, recycling ethanol and obtaining an extractive; performing liquid-liquid partition of n-butyl alcohol and water on the extractive to obtain the separated part of the n-butyl alcohol; purifying the separated part of the n-butyl alcohol by macroporous resin to obtain the effective part of perilla leaf. The sum of the weight of caffeic acid, caffeic acid vinyl ester, rosmarinic acid and methyl rosmarinate accounts for 50 to 70 percent of the effective part, and the effective part contains 5 to 10 percent of scutellarin. A modern separation method and pharmacological activity screening are combined to determine the best effective part, so that the ingredient of the obtained effective part is more clear, the content of the active components is high; the result of experiment in vitro and vivo shows that the effective part of perilla leaf resisting hyperuricemia can inhabit the xanthine oxidase activity to achieve the effect of reducing trioxypurine.

The invention provides a gas and liquid two-phase flow uniform-distributing device and a gas and liquid two-phase flow mixing method for a plate-fin heat exchanger. The plate-fin heat exchanger internally comprises a fin channel area 1, a liquid distributing seal, a fin channel area II, a gas distributing seal, and a fin channel area III from bottom to top along the flowing direction of fluid; the fin channel area 1, the fin channel area II and the fin channel area III are channels that are internally provided with heat exchanging fins; and the length of the liquid distributing seal and the length of the gas distributing seal are consistent with the width of the heat exchanger. The invention also relates to a method for mixing the gas and liquid two-phase flow in the plate-fin type heat exchanger. In the invention, the device and the mixing method have the advantages that when the gas and liquid two-phase flow is gathered in the middle of the heat exchanger, the distributing uniformity of the two-phase flow fluids can be improved, the quantity of the gas and liquid two-phase flow fluids passing by the inlet and outlet can be reduced, the flow for re-distributing the two-phase fluid can be reduced, the resistance of the fluid can be reduced, and the length of the heat exchanger can be reduced under the condition of ensuring the area of the heat exchanger.

The invention relates to a liquid distributor or collector for liquid chromatography columns with a preferably round base. Said liquid distributor or collector is particularly suitable for columns that have a large diameter in relation to the packing height.

The invention discloses a detection method of environmental hormone dibutyl phthalate (DBP) in traditional Chinese medicinal materials, which belongs to the technical field of analysis and detection, and comprises the following steps of carrying out ultrasonic-assisted extraction on the traditional Chinese medicinal materials, and carrying out secondary purification, namely a purification method of removing water-soluble impurities by dichloromethane-water phase liquid-liquid partition, and removing fat-soluble impurities by an ODS (octadecyl silane)-C18 solid phase column is adopted; and the advantages of high GC-FID (gas chromatography-flame ionization detector) sensitivity, good separation effect and accuracy in quantification are utilized, so that the degree of accuracy, the degree of precision and the reproducibility can be ensured. Potential long-term harms can be formed when people take foods or the traditional Chinese medicinal materials containing the environmental hormone dibutyl phthalate for a long time; and therefore, conditions of higher requirements on cultivation, transportation and storage of the traditional Chinese medicinal materials need to be proposed, and strengthening monitoring and early warning on DBP has certain practical applicability, and the method has significance. The detection method can accurately detect the DBP content in the traditional Chinese medicinal materials, and is low in cost, and is simple, convenient and fast.

Liquid dispenser for discharging pharmaceutical liquids, having a housing, an outlet opening and an outlet valve assigned to the outlet opening. The outlet valve includes a pressure chamber arranged upstream of a valve opening and delimited to one side by a valve plate of a valve body. By increasing the pressure in the pressure chamber, the valve can be opened. The pressure chamber has a flat form and has a large surface area in contact with liquid in relation to the volume.At least one portion of the valve plate which is in contact with liquid in the pressure chamber is of a valve plate material produced using metallocenes as catalysts.

The invention discloses a gas chromatography-negative chemical source-tandem mass spectrometry detection method for fipronil and a metabolite amide fipronil of the fipronil in a bird egg. By means ofthe method, the residual amounts of the fipronil and the metabolite amide fipronil of the fipronil in the bird egg can be accurately determined. Acetonitrile is added into a bird egg sample to extracta target and obtain to-be-purified liquid, the to-be-purified liquid is subjected to liquid-liquid partition degreasing through n-hexane and purification through a matrix dispersion purification tube, qualitative analysis is conducted on the target under a monitoring mode of a gas chromatography-negative chemical source-tandem mass spectrometer according to retention time and ion pair informationcomparison, and quantification is conducted through an internal standard method. The method is high in analysis speed, high in sensibility and good in reproducibility and accuracy, and the novel detection method is provided for guaranteeing the bird egg quality safety.

A value determining method for a sulfonamide veterinary drug residual matrix reference material in pork is provided. The method includes a matrix reference material pretreatment step. The pretreatmentincludes (1) a step of extraction, namely adding an extracting solvent into a matrix reference material for target substance extraction, and allowing an obtained liquid supernatant to pass through ananhydrous sodium sulfate column to obtain an extract; and (2) a step of purification, namely a step of subjecting the extract obtained in the step (1) to water-bath rotary evaporation drying, addinga mobile phase to a constant volume to dissolve the extract; performing filtration through a liquid-liquid partition purification process and performing filtration to obtain the pretreated matrix reference material, wherein the anhydrous sodium sulfate column is infiltrated with acetonitrile in advance and the mobile phase is saturated with n-hexane in advance. The n-hexane-saturated mobile phaseis added to the extract of the sulfonamide veterinary drug residual matrix reference material to a certain volume, thus reducing distribution of sulfonamide drug in an extract liquid into an organic phase during liquid-liquid partition. The sulfonamide drug recovery rate is 95.7-104.8%, and the relative standard deviation is less than 5% (with n being 6).

A liquid dispensing nozzle including a liquid dispensing opening and a removable cap designed to cover the recess. The cap has an exterior envelope and an interior envelope that are coaxial, mounted mobile relative to one another in an axial direction and each have a sealing surface and able to assume a before first use storage configuration, in which the sealing surfaces of the exterior envelope and the interior envelope are in hermetically sealed contact with one another. The cap further includes a safety envelope mounted mobile relative to the exterior envelope between a configuration for unscrewing the cap when a bearing force exerted on the safety envelope has an intensity greater than a predetermined threshold, and a safety configuration when the bearing force has an intensity less than a predetermined threshold or when no bearing force is exerted on the safety envelope.