The invention relates to a bioreactor for producing tissue engineering products, which comprises a waste liquid bottle, a fluid replacement bottle, a liquid storage bottle, a four-nature mixer, an acid liquor bottle, an alkali liquor bottle and a bioreaction box assembled by a reaction box body, a reaction box cover, layer boxes, a constant temperature jacket and a sealing gasket. The layer boxes are superposed from bottom to top in an alternate manner of forward direction and backward direction in the reaction box; the overflow gutter of the pan of the upper layer is over the opposite end of the overflow gutter of the pan of the lower layer, and one end of the overflow gutter of the pan at the lowest layer is close to the liquid outlet of the reaction box body and one end of the positioning pin of the pan at the uppermost layer is arranged below a liquid baffle. Compared with the prior art, the bioreactor has good expansibility, simple structure, small volume, few pipes, high universal property and wide application range, is suitable for mass production, not only applicable for the culture of tissue engineering skin at gas-liquid interfaces to produce tissue engineering skin but also for the systemization and production of scaffold tissue engineering products (such as bones, cartilage, muscle tendon and the like).