127 results about "Phenylacetone" patented technology

The invention relates to a method for biosynthesis of tyrosol in Escherichia coli and application of tyrosol, which belongs to the field of bioengineering technology. According to the method for biosynthesis of tyrosol in Escherichia coli, tyrosine or glucose is used as a substrate, (4-hydroxyphenyl)pyruvic acid is produced under the catalysis of ammonialyase coded by Escherichia coli; (4-hydroxyphenyl)acetaldehyde is produced under the action of the microzyme 4-hydroxyphenylpyruvate decarboxylase; (4-hydroxyphenyl)acetaldehyde is catalyzed by alcohol dehydrogenase so as to produce tyrosol; and a phenylacetaldehyde dehydrogenase gene of Escherichia coli is knocked out at the same time so as to block the transformation channel for (4-hydroxyphenyl)acetaldehyde into (4-hydroxyphenyl)acetic acid and promote accumulation of (4-hydroxyphenyl)acetaldehyde and transformation of (4-hydroxyphenyl)acetaldehyde into tyrosol. The invention provides a novel production approach for tyrosol; and the method lays a foundation for large-scale industrial production of tyrosol and has important economic values and social benefits.

The invention relates to a detection method of determining 16 types of photoinitiators in a paper printing and packaging material, which is used for determining residual amounts of the 16 types of photoinitiators of 2-hodroxy-2-methyl-1-phenylacetone, mehtyl phenylglyoxylate, benzophenone and the like and is characterized by comprising the following concrete steps of: a, sample pretreatment; b, preparation of a standard work solution; c, instrumental analysis; and d, result calculation. Compared with the prior art, through sample pretreatment and optimization of instrumental analysis conditions, the detection method has the advantages that efficiency is high, the 16 kinds of photoinitiators can be simultaneously analyzed and determined within 25m; and printing ink impurities in a sample extraction solution can be better removed in a liquid-liquid distribution impurity removal mode adopted in the sample pretreatment process, so that cost is low, consumption is little, efficiency is high, and sensitivity is high; and in addition, the detection method also has the advantages of high accuracy and good repeatability.

The invention discloses a high-fire-retardant ultraviolet curing coating. The high-fire-retardant ultraviolet curing coating comprises the following raw materials: urethane acrylate, epoxy acrylate, epoxidized soybean oil acrylate, phosphorus-containing acrylate, N-vinyl pyrrolidone, polyethylene glycol acrylate, tri(propylene glycol) diacrylate, pentaerythritol triacrylate, trimethylolpropane triacrylate, benzophenone, 2-methyl-2-hydroxyl-1-phenylacetone, coumarone, nano-silica, nano aluminum hydroxide, ammonium polyphosphate, silica powder, expanded graphite, a flattening agent, a defoaming agent, a wetting agent, a dispersant and a coupling agent. The high-fire-retardant ultraviolet curing coating disclosed by the invention is good in flame retardance property, high in adhesion force, excellent in comprehensive performance and long in service life.

The invention discloses a soluble hydrogel microsphere and a preparation method and an application thereof in single cell detection. The preparation method comprises following steps: evenly mixing acrylamide, N,N-bis(acrylamide)amide, acetic acid, and 2-hydroxyl-2-methyl-1-phenyl-1-acetone, adding sodium hydroxide to obtain a prepolymer solution; adopting a single emulsion device, taking the prepolymer solution as an inner phase and an oil phase substance as an outer phase to obtain micro droplets, and carrying out online polymerization to obtain the microsphere. The single cell detection method comprises following steps: marking a bar code on the soluble hydrogel microsphere; injecting the soluble hydrogel microsphere, single cell suspension, and lysate of reverse transcriptase into a droplet micro reactor to form oil-in-water droplets, breaking the droplets, dissolving the soluble hydrogel microsphere, carrying out specific catalytic reverse transcriptional reactions and cDNA amplification; and differentiating single cells through the bar codes. The provided single cell detection method can improve the utilization rate of reverse transcriptase and solves the problem of channel obstruction.

The embodiment of the invention provides ultraviolet light curing ink and a preparation method of the ultraviolet light curing ink, wherein the ultraviolet light curing ink comprises the following ingredients: methacrylic acid isobornyl thiocyanoacetate, 2-hydroxy acrylic resin, 1-hydroxy cyclohexyl phenylacetone, essence microcapsules, pigments and alkyd resin. The ultraviolet light curing ink provided by the embodiment of the invention is favorable for improving the ink toughness, and further, the product quality is improved.

The invention relates to an energy transmission optical fiber, which comprises an optical fiber and a layer of low-refractive-index coating coated on the surface of the optical fiber. The energy transmission optical fiber is characterized in that low-refractive-index coating comprises the following components in percentage by weight: 10 to 25 percent of fatty group urethane acrylate, 3 to 10 percent of vinyl silicone oil, 8 to 15 percent of perfluoroalkylethyl acrylate, 3 to 10 percent of TMMPS, 40 to 65 percent of trifluoro ethyl methacrylate and 3 to 8 percent of 2-hydroxy-2-methyl-1-phenylacetone. The energy transmission optical fiber has the advantage of reducing the production cost of the energy transmission optical fiber.

The invention provides an ultraviolet-quick-curing dendriform resin, and a divergent preparation method and application thereof. Ethylenediamine (EDA), diethylenetriamine (DETA), triethlenetetramine (TETA) and other polyamines are used as initiation cores, tripropylene glycol diacrylate (TGPDA), ethoxylated trimethylolpropane triacrylate (TEPTA) and other polyfunctional group monomers are used as branching units, and a divergent method is utilized to prepare the regular-structure highly-branched high-double-bond-density low-viscosity dendriform series resins containing different acrylate double bonds at terminal groups; benzoin aether and 2-hydroxy-2-methyl-1-phenyl-1-acetone with different photoinitiation activities are used as photoinitiators, are matched and uniformly mixed with the dendriform series resins containing different acrylate double bonds at terminal groups in a dark room, and are cured under the irradiation of an ultraviolet curing lamp to prepare different product series of quick-curing dendriform photosensitive resins. The preparation method can implement large-scale application and production, and has the characteristics of small pollution, high curing speed and high production efficiency.

The invention relates to a trifunctional photoinitiator and a preparation method thereof. The molecular formula of the trifunctional photoinitiator is C43H44O13, and the molecular weight of the trifunctional photoinitiator is 769.82. 2-hydroxyl-2-methyl-phenylacetone (Darocur 1173 or HMPP) and chloridized metaphthalic anhydride which are used as raw materials undergo an esterification reaction tointroduce acid anhydride, and the acid anhydride reacts with two molecules of a photoinitiator [4-(2-hydroxyethoxy)phenyl]-2-methyl-1-acetone (Darocur 2959 or HHMP) to obtain the trifunctional photoinitiator HTH containing one molecule of Darocur 1173 and two molecules of the Darocur 2959 group. The photoinitiator contains three active groups, sp the photoinitiator has the advantages of increasedmolecular weight, an enhanced activity, excellent mobility, excellent volatility and excellent thermal stability.

The invention discloses ultraviolet light polymerization water-based paint universal for metal and non-metal and a preparation method of the paint. The ultraviolet light polymerization water-based paint universal for metal and non-metal comprises the following raw materials in parts by mass: 60-70 parts of vinyl ester resin, 38-46 parts of urethane acrylate, 1-2 parts of 2-hydroxy-2-methyl-1-phenylacetone, 0.5-1 part of bimercaptoacetic acid isooctyl di-n-octyltin, 35-40 parts of ethanol and 150-180 parts of water. The paint is short in curing time, that is, the curing time is 3 minutes and the adhesion capability to a substrate is of 1 grade, is good in stability and free of layering after being preserved for 6 months. The paint is simple in preparation method and applicable to popularization and application in a wide range.

The invention relates to a method for preparing (1R, 2S)-norephedrine, (1R, 2R)-norpseudoephedrine and a midbody thereof. The method comprises the following steps: in the reaction process in the first step, by taking a carrot as a medium, carrying out bio-transforming on 2-oximido-1-phenylacetone and reducing into (R)-2-oximido-1-phenyl propyl alcohol; in the second step, reducing (R)-2-oximido-1-phenyl propyl alcohol into a mixture of (1R, 2S)-norephedrine and (1R, 2R)-norpseudoephedrine; adding a chiral reliquid reagent (R)-O-acetyl mandelic acid and decomposing, thereby acquiring an optical pure (1R, 2S)-norephedrine and (1R, 2R)-norpseudoephedrine monomeric compound.

The invention provides a method for synthesizing substituted phenyl acetone. Halide aryl compound reacts with magnesium powder to produce Grignard reagent aryl magnesium halide; the aryl magnesium halide reacts with propylene oxide to produce 1-aryl-2-propanol; the 1-aryl-2-propanol reacts with oxydol under the catalyst of sodium tungstate and quaternary ammonium salt to produce 1-substituted phenyl acetone. In the method, the material is easily obtained, the process is simple and practical and the overall yield of the product reaches 83 percent.

The invention discloses a polymerizable hydroxyalkyl benzophenone derivative photoinitiator and a preparation method thereof. 2-hydroxyl-2-methyl-1-phenylacetone (Darocur1173) is modified with (methyl) acryloyl chloride under the ice bath condition, and carbon-carbon double bonds which can participate in a photocuring reaction is introduced after hydroxyl esterification of Darocur1173, so that the photoinitiator which can participate in curing is prepared, the part, which is not photolyzed, of the initiator can be effectively prevented from being migrated to the surface of a coating, the product quality is guaranteed, the requirements of the food packaging field and the drug packaging field can be met, and the initiation efficiency of the modified initiator is high.

The invention discloses a tank-interior electrochemistry composite technique of methoxylbenzyl-ketone relates to electrochemistry technique field. Adopt Pt filament as positive pole and stainless fin as negative pole in bi-room electrolysis tank, acetic acid-acetic acid anhydride as disslovant, kalium acetate as electrolysis support, at certain temperature, in the electrolysis tank in positive pole room the anethole and lead acetate both as electrolysis basal material. The anethole directly electrolysis reaction on the positive pole takes place at the same time the indirect oxidation with lead tertraacetic as intermediate reactor develops. Hydrolyric decomposite the obtained product with sulfuric acid and further process to acquire the final product methoxylbenzyl-ketone. The invention has got advantages such as simple and easy reaction material, environmental reaction process, safe operation, high productivity and low cost, is a technique of high added value.

The invention discloses coating, and particularly relates to wear-resistant ultraviolet curing magnetic roller coating and a preparation method thereof. The coating is composed of the following raw materials by weight: 8 to 18 parts of graphene; 0.2 to 1.2 parts of methyl silicone oil; 2 to 12 parts of organosilicon resin; 0.2 to 1 part of organic modified polysiloxane acrylic acid type leveling agent; 0.2 to 2.5 parts of fumed silica, 10 to 32 parts of urethane acrylate, 0.01 to 15 parts of hexanediol diacrylate, 1 to 8 parts of 2-hydroxy-2-methyl-1-phenyl-1-acetone, 2 to 16 parts of inositolhexaphosphate, 0.25 to 2.5 parts of a titanate coupling agent, 5 to 15 parts of alicyclic epoxy resin and 10 to 18 parts of zinc powder. The coating is prepared by multi-step mixing and dispersing. The coating can conduct electricity after being subjected to ultraviolet curing, and has enough hardness and excellent wear resistance and tensile strength.

The invention provides a preparation method of fingolimod hydrochloride (1). The method comprises the following steps: carrying out a reducing reaction on 3-nitro-1(4-octylphenyl)propyl-1-one (2) to obtain a compound 1-(3-nitropropyl)-4-octylbenzene (3); reacting 1-(3-nitropropyl)-4-octylbenzene (3) with formaldehyde to generate 2-(4-octylphenylethyl)-2-nitro-propane-1,3-diol (4); and reducing the compound 4, and carrying out salt formation on the reduced compound 4 and hydrochloric acid to generate the 2-(4-octylphenylethyl)-2-amino-propane-1,3-diol hydrochloride (1) which is the fingolimod hydrochloride. The method has the advantages of short synthetic route, cheap and easily available synthetic raw materials, no obvious pollution in the synthetic process, and total yield reaching 40-45%, is a simple and economic method for preparing the fingolimod hydrochloride. The invention also provides a synthetic method of intermediates.

The invention belongs to the technical field of anti-wear and anti-scratching processing of the surface of a plastic product and particularly relates to an anti-yellowing UV (ultraviolet) varnish. The anti-yellowing UV varnish is characterized in that the anti-yellowing UV varnish comprises the following components in percentage by weight: 50-80% of aliphatic polyurethane hex-acrylate, 15-30% of butyl acrylate, 0-15% of dipropylene glycol diacrylate, 1-4% of 2-hydroxyl-2-methyl-1-phenylacetone and 1-4% of 1-hydroxycyclohexyl phenyl ketone. The anti-yellowing UV varnish has good anti-yellowing performance and coating flexibility and is particularly suitable for use in anti-wear and anti-scratching processing of a plastic hose.

The invention discloses a method for preparing phenylacetone from phenylacetic acid, and belongs to the technical field of preparation of the phenylacetone. The method comprises the following steps: a, adding the phenylacetic acid, sodium acetate and acetic anhydride into an enamel reaction kettle, and uniformly stirring the phenylacetic acid, the sodium acetate and the acetic anhydride; b, heating the enamel reaction kettle till acetic acid is distilled off from the tower top of a distilling tower, and condensing substances, distilled from the distilling tower, through a plastic coiler to enable the substances to flow back into the enamel reaction kettle for reaction, thus obtaining reaction liquid; c, heating the reaction liquid, and distilling out the acetic acid and the acetic anhydride in sequence; d, cooling the reaction liquid to normal temperature, adding water, thus obtaining separation liquid, and performing standing layering on the separation liquid, thus obtaining first oil liquid on the upper layer; e, adjusting the pH value of the first oil liquid to be 12 through a sodium hydroxide solution, and performing alkaline hydrolysis, thus obtaining alkaline hydrolysis liquid; f, standing the alkaline hydrolysis liquid, thus obtaining second oil liquid on the lower layer; g, performing reduced pressure distillation on the second oil liquid, thus obtaining the phenylacetone. According to the method disclosed by the invention, by improvement on a production process of the phenylacetone, the prepared phenylacetone has the characteristics of low cost and high purity.