108results about How to "Synthetic raw materials are cheap" patented technology

The invention provides a carbon-coated cobalt sulfide material as well as a preparing method thereof and application of the carbon-coated cobalt sulfide material as a catalyst in the aspect of hydrogen production through the electric catalytic cracking of water and belongs to the fields of catalyst synthesis technologies and application. An organic matter rich in sulfur is used as a sulfur source and a carbon source, a cobalt salt is used as a cobalt source, the organic matter and the cobalt salt are forged in an inert atmosphere after being mechanically mixed uniformly, and the carbon-coated cobalt sulfide material can be obtained. The preparing method is simple and controllable, adopts cheap raw materials, has good sample repeatability, spends short time in the synthesis process, has low requirements on equipment and is suitable for massive production. As an active substance is effectively protected by a carbon coating layer from electrolyte corrosion, the electric conductivity of the material is improved, and accordingly, the material shows excellent hydrogen production electric catalysis performance in acid, neutral as well as alkaline electrolytes. The most important is that the development of the catalyst capable of being used in the whole pH range opens a novel path for the preparation of a cheap, efficient and environment-friendly non-noble metal electric catalysis material for hydrogen production.

The invention discloses a 1T-MoS2-modified ZnCoS solid solution hollow dodecahedral nanocomposite and a preparation method and application thereof. Firstly, a ZnCo-MOF is calcined at a high temperature to obtain a derivative of the ZnCo-MOF, then the derivative and molybdate are subjected to hydrothermal vulcanization reaction to obtain a MoS2/ZnCoS nanocomposite, and the ZnCo-MOF is a bi-metal organic framework material and is obtained through reaction of cobalt acetate, zinc acetate and dimethylimidazole. The bi-metal organic framework material with a large specific surface area and a stablethree-dimensional space structure is used as a template, the ZnCo bi-metal oxide derivative is obtained through high-temperature calcination, and finally a mixture of the derivative and the molybdateis subjected to hydrothermal vulcanization to obtain the transition metal sulfide nanomaterial with high catalytic activity. The prepared hollow polyhedral MoS2/ZnCoS nanocomposite has high performance of producing hydrogen by water decomposition under photocatalysis.

The invention provides a carbon-coated vanadium nitride electrocatalyst. Carbon-rich organic matter is used as a carbon source; metal vanadium salt is used as a vanadium source; urea, ammonium carbonate, ammonium hydrogencarbonate and the like are used as a nitrogen source; and carbon-coated vanadium nitride nanoparticles are obtained through one-step calcination after the constituents are uniformly mixed through a mechanical method. The carbon-coated vanadium nitride electrocatalyst has the advantages that the raw material is cheap; the synthesis method is simple; the controllability is high;the obtained vanadium nitride is nanoparticles and coated with amorphous carbon layers, so that the electrical conductivity of the material is enhanced; and the carbon-coated vanadium nitride nanomaterial prepared by the method has uniform chemical composition and higher purity and crystallinity, and exhibits hydrogen production catalytic activity to a certain extent.

A method for synthesizing pure silicon Beta molecular sieves in a hydrothermal and fluoride-free manner belongs to the technical field of preparation of zeolite molecular sieves. The method is implemented by adding Beta molecular sieve seed crystals into an initial gel to synthesize the pure silicon Beta molecular sieves under hydrothermal and fluoride-free conditions. Specifically, the method comprises taking low-price silicon sources, templates and alkali sources as well as the homemade pure silicon Beta molecular sieve seed crystals as the raw materials, dissolving the silicon sources, the templates, the alkali sources and the seed crystals into distilled water, performing mixing to obtain a uniform gel, and then performing hydrothermal crystallization; washing and drying the hydrothermally crystalized products to obtain the pure silicon Beta molecular sieves. Compared with the prior art, the method for synthesizing the pure silicon Beta molecular sieves in a hydrothermal and fluoride-free manner has the advantages of being low in price of the synthetic raw materials, simple in synthesis and free from application of fluoride ions during synthesizing processes, thereby having a good industrialized application prospect.

The invention provides a preparation method of graphite-phase carbon nitride solid fluorescent powder and application thereof in quickly developing latent fingerprints on different object surfaces. The graphite-phase carbon nitride solid fluorescent powder can be used for fluorescence labeling, and can be used in the fields of crime scene criminal detection and the like. The invention aims to quickly develop latent fingerprints on different individual and different object surfaces by utilizing the characteristic of photoluminescence of the nano graphite-phase carbon nitride. The high-fluorescence-responsivity graphite-phase carbon nitride solid fluorescent powder is prepared by using melamine as an N-containing precursor and using sodium chloride and potassium chloride as assistants. The application process in fingerprints comprises the following steps: lightly dipping a fingerprint brush into a small amount of graphite-phase carbon nitride solid fluorescent powder, lightly brushing the suspected fingerprint region, removing the excess powder, putting under a 365nm ultraviolet lamp, and observing the special blue light which is conveniently photographed and stored by a digital camera. Due to the specific adsorptivity of the nano material, the affinity between the nano powder and fingerprint ridges is high. The graphite-phase carbon nitride solid fluorescent powder can be used for successfully extracting fingerprints on different individual and different object surfaces.

The invention discloses pseudomonas putida WP07, a preparation method and purpose. The pseudomonas putida WP07 is preserved in the China General Microbiological Culture Collection Center, and the preservation number is CGMCC No.17760. By a microbiological method, pigwash oil is converted into biodegradable plastic PHA which has environment affinity, so that resource utilization and innocent treatment of the pigwash oil can be realized, the preparation cost of the PHA can also be reduced, and the pseudomonas putida WP07 has favorable application prospects.

The invention provides a red fluorescent material. The chemical formula of the red fluorescent material is Ca2AlNbO6: Mn4+, and the luminescence center is a non-rare-earth activator Mn4+. The invention provides a preparation method of the red fluorescent material. The preparation method comprises the following steps: weighing the raw materials according to the molar ratio of the elements, carryingout high-temperature solid-phase reaction, adding a proper amount of flux to control the solid-phase synthesis temperature, introducing a proper amount of a charge compensation agent, ensuring the pure phase range of the sample, furthermore improving the luminous performance of the perovskite structure niobium aluminate red fluorescent material, and finally obtaining high-efficiency and stable red fluorescent powder. The perovskite structure niobium aluminate is used as a matrix, the Mn4+ is used as an activator, no expensive rare earth element is used, the raw materials and the final productare free of harmful substances such as fluorine, and the fluorescent powder is used for strong absorption of exciting light of the ultraviolet band and blue light band, the red light wave with the proper bandwidth is emitted, and the red fluorescent material is suitable for being applied to the fields of illumination and display of warm white light LED devices excited by ultraviolet or blue lightLED chips.

The invention discloses a novel nicotinamide ribose phosphate transferase inhibitor as well as a synthetic method and application thereof. The novel nicotinamide ribose phosphate transferase inhibitor is a compound or pharmaceutically acceptable salts thereof shown in the structural formula I in the specification. The novel nicotinamide ribose phosphate transferase inhibitor is prepared from cheap synthetic raw materials, concise in route, simple in operation and suitable for industrial production; the obtained compound is excellent in antitumor activity and is expected to be developed as a new antitumor drug.

The invention discloses a novel binary eutectic solvent and application of the binary eutectic solvent in NH3 trapping. The eutectic solvent is composed of a component A and a component B; the component A is a proton type ionic salt, and the component B is a phenolic compound or an imide compound. In the eutectic solvent provided by the invention, the component A is a hydrogen bond acceptor, the component B is a hydrogen bond donor, and the component A and the component B have certain weak acidity and can provide double active sites for reversible chemical absorption of NH3. The eutectic solvent provided by the invention has the characteristics of large NH3 absorption capacity, high selectivity, good cycle performance and low volatility, and an efficient, green and environment-friendly absorbent is provided for separation and recovery of NH3 in industrial tail gas.

The invention relates to the field of functional macromolecular materials, in particular to novel linear temperature-sensitive type polyurethane and a preparation method thereof. The preparation method of polyurethane comprises steps as follows: polycarbonate diol and dimethylolpropionic acid are added to an organic solvent and are mixed uniformly at the temperature of 75-85 DEG C under the protection of nitrogen, then hexamethylene diisocyanate and a catalyst are added, the mixture is stirred at the temperature of 75-85 DEG C and reacts for more than 3 h to generate linear polyurethane with isocyanato as an end group, ethylenediamine and triethylamine are added, the mixture is stirred to react for 2 h or longer, linear polyurethane with amino as an end group is obtained, N-isopropyl acrylamide is added, the mixture is stirred to react for 12 h or longer, then deionized water is added, an organic solvent is removed through rotary evaporation in a vacuum state, and the novel linear temperature-sensitive type polyurethane is obtained. Two ends of a polyurethane chain segment of the novel linear temperature-sensitive type polyurethane are directly sealed with N-isopropyl acrylamide, no other chain segments are contained, the synthetic method is simple, the synthesis and chemical grafting steps of poly(N-isopropyl acrylamide) are omitted, synthetic raw materials are also saved, and the cost is reduced.

The invention belongs to the technical field of furfuryl alcohol preparation, and discloses a method for preparing furfuryl alcohol by catalyzing transfer hydrogenation of furfural through non-noble metal-loaded nitrogen-doped carbon. According to the method, a cobalt oxide-loaded nitrogen-doped carbon catalyst is used for catalyzing furfural to prepare furfuryl alcohol, wherein nitrogen-doped carbon in the catalyst is a carrier, and cobalt oxide in the catalyst is an active component. According to the method, a nitrogen-doped carbon material loaded by cobalt oxide is used as the catalyst, organic alcohol is used as a solvent and a hydrogen donor, and transfer hydrodeoxygenation of furfural is catalyzed to synthesize furfuryl alcohol; the method is simple in the whole process, easy to operate and low in cost; a reaction system is green; the catalyst is high in activity; the furfuryl alcohol is high in selectivity and yield; and the method has wide industrial application prospects. H2 is prevented from being directly used, and the organic alcohol serves as the hydrogen donor, so storage and use are convenient, the requirement of a reaction solvent on hydrogen solubility is lowered,and hydrogenation effect is good.

The invention discloses a preparation method of a carbon-coated vanadium sulfide electrocatalyst and an application thereof in an aspect of serving as an electro-catalysis cracking water hydrogen-generating catalyst, and belongs to the field of catalyst synthetic technologies and applications. Disulfide vanadium is used as a layered material, more and more focused by people in recent years. However, there is less report about V3S4, and an electro-catalysis aspect is not reported yet. The method is capable of using a sulfur-enriched organic matter as a sulfur source and a carbon source, and using metal vanadic salt as a vanadium source, after uniformly mixing through a mechanical method, acquiring carbon-coated vanadium sulfide nanoparticles through one-step calcining. The method is rapid and simple, and an acquired material is the hydrogen-generating catalyst which is uniform in chemical composition and has electrocatalytic activity in full PH electrolyte.

The invention relates to the field of material synthesis, and discloses a composite material with a light hydrocarbon adsorption function, a preparation method of the composite material, a method for removing light hydrocarbons by using the composite material and application of the composite material. The composite material comprises an association structure formed by a polymer and a copper-based metal organic framework material loaded in the association structure, the weight ratio of the polymer to the copper-based metal organic framework material is 1: (1-15), and the polymer is selected from at least one of polyvinyl formal, polypropylene, polyethylene sulfone and polyamide. The composite material is stable in framework structure and has high mechanical stability, the pore volume, the pore diameter and the specific surface area of the composite material are large, the light hydrocarbon adsorption capacity is high, the method for preparing the composite material is simple and environmentally friendly, synthesis raw materials are low in price, and large-scale production and application are easy.

The invention discloses an indirubin derivative and application of the indirubin derivative used as a dual-target inhibitor of CDK/HDAC. The indirubin derivative can effectively inhibit the activity of the CDK/HDAC, and can be used as the dual-target inhibitor of CDK/HDAC; and in addition, according to the indirubin derivative and the application of the indirubin derivative used as the dual-targetinhibitor of CDK/HDAC, synthetic raw materials are cheap, the cost is low, antitumor activity is obvious, and the indirubin derivative can be used for novel high-efficiency and low-toxicity CDK/HDACdual-target inhibitor antitumor drugs.

The invention provides a carbonic anhydrase fluorescent probe with high brightness and high light stability. The structural formula of the probe is shown as (1), the probe is 4-substituted naphthalimide dye which can be used for carbonic anhydrase detection and fluorescence imaging, and the dye has the advantages of cheap synthetic raw materials, simple method, easiness in derivation and the like.Researches show that a benzenesulfonamide structure contained in the compound can be combined with carbonic anhydrase in cells in a high-selectivity manner; azetidine is introduced to the 4-site of the naphthalimide dye, so that the TICT process can be inhibited, and the brightness and the light stability of the dye are improved. The molar extinction coefficient of the dye in ethanol reaches 15382 M<-1>cm<-1>, and the quantum yield reaches 0.52. The dye shows short fluorescence lifetime in a water environment and shows long fluorescence lifetime in a weak polarity environment after being combined with carbonic anhydrase, and the fluorescence lifetime is increased from 4.27 ns to 10.6 ns. The carbonic anhydrase dye has very high brightness and light stability, can quickly mark carbonic anhydrase and is applied to the fields of carbonic anhydrase detection, fluorescence imaging, fluorescence lifetime imaging and the like.

The invention discloses a furazolidone AOZ-D4 synthesis method, which comprises: 1) carrying out a reaction on deuterated acetic acid and bromine in the presence of TFAA to obtain deuterated bromoacetic acid; 2) carrying out a reaction on the deuterated bromoacetic acid and oxalyl chloride (or SOCl2) in DMF, adding benzyl alcohol, and continuously carrying out a reaction to obtain deuterated benzyl bromoacetate; 3) adding the deuterated benzyl bromoacetate into the THF solution of NaBD4, and carrying out a reaction to obtain deuterated bromoethanol; 4) dissolving hydrazine hydrate in dehydrated alcohol, adding NaOH, stirring, adding the deuterated bromoethanol, and carrying out a reaction to obtain deuterated 2-hydroxyethyl hydrazine; and 5) carrying out a reaction on the deuterated 2-hydroxyethyl hydrazine and dimethyl carbonate in the presence of an alkali to synthesize furazolidone AOZ-D4.

The invention provides a preparation method of fingolimod hydrochloride (1). The method comprises the following steps: carrying out a reducing reaction on 3-nitro-1(4-octylphenyl)propyl-1-one (2) to obtain a compound 1-(3-nitropropyl)-4-octylbenzene (3); reacting 1-(3-nitropropyl)-4-octylbenzene (3) with formaldehyde to generate 2-(4-octylphenylethyl)-2-nitro-propane-1,3-diol (4); and reducing the compound 4, and carrying out salt formation on the reduced compound 4 and hydrochloric acid to generate the 2-(4-octylphenylethyl)-2-amino-propane-1,3-diol hydrochloride (1) which is the fingolimod hydrochloride. The method has the advantages of short synthetic route, cheap and easily available synthetic raw materials, no obvious pollution in the synthetic process, and total yield reaching 40-45%, is a simple and economic method for preparing the fingolimod hydrochloride. The invention also provides a synthetic method of intermediates.

The invention provides a high-brightness lipid droplet cell nucleus multicolor imaging fluorescent probe. The probe is 4-substituted naphthalimide dye which can be used for multicolor fluorescence imaging of lipid droplets and cell nucleuses in living cells, and the dye has the advantages of low synthesis raw material cost, simple method, easiness in derivation and the like. Researches show that an azetidine structure is introduced to the 4-site of a naphthalimide matrix in the dye, so that the rigidity and planarity of the dye are improved, the TICT process is effectively inhibited, the molarextinction coefficient of the dye in ethanol is about 15,000 M<-1>cm<-1>, the fluorescence quantum yield is about 0.6, and the dye has very high brightness and light stability. According to the present invention, a morpholine ring, N,N-dimethyl and other basic groups are introduced to the dye, such that the dye can target the cell nucleus, and the molecule has the appropriate lipid solubility soas to achieve the precise positioning of the cell nucleus and the lipid droplet; the dye has very high brightness and light stability, can rapidly mark cell nucleuses and lipid droplets, and can be used in the fields of multicolor fluorescence imaging and the like.

The invention discloses a domino catalytic system to prepare branch polythene and application, which is characterized by the following: comprising the catalytic system as multiple allocating catalytic system; setting as main accelerant, oligomerisation catalyst promoter and copolymerization catalyst promoter; setting the formula of the main accelerant as AnML4-n; setting n as 1, 2, 3 or 4; expressing ligand beta-diketone with A; setting the M as Ti or Zr; setting the L as assistance coordination group; setting the oligomerisation catalyst promoter as alkyl aluminium; setting the oligomerisation catalyst promoter as aluminium alkyl oxygen alkyl and three isobutyl aluminum; preparing branch polythene under the function of main accelerant, oligomerisation catalyst promoter and copolymerization catalyst promoter. This invention can decrease the cost of branch polythene, which possesses simple craft and easy control.

The invention relates to the field of high polymer functional materials, in particular to a linear temperature-sensitive polyurethane and a preparation method thereof. The preparation method includes: S1. preparing a primary hydroxyl group-containing monomer molecule M with temperature-sensitive effect from N-isopropylacrylamide and ethanolamine; S2. subjecting polycarbonate diol, dimethylolpropionic acid, hexamethylene diisocyanate and a catalyst to reaction to generate polyurethane, then adding the monomer molecule M synthesized in S1 to cap two ends of the obtained polyurethane, finally adding triethylamine and deionized water, and carrying out vacuum rotary evaporateion to remove the organic solvent, thus obtaining the linear temperature-sensitive polyurethane. According to the temperature-sensitive polyurethane provided by the invention, the monomer molecule M plays a temperature-sensitive role, two ends of the polyurethane chain segment are directly capped by the monomer molecule M, and no other chain segment is contained. The synthesis method is simple, omits the poly(N-isopropylacrylamide) chain segment synthesis and chemical grafting steps, also saves the synthesis raw materials, and reduces the cost.

The invention discloses a preparation method of a NiV2S4 nanoparticle electrocatalyst and an application of the NiV2S4 nanoparticle electrocatalyst as electrocatalytic cracking hydrogen aquatic production catalysts, and belongs to the field of catalyst synthesis technology and application. Sulfur-rich organic matter is used as a sulfur source; metal vanadium salt is used as a vanadium source; metal nickel salt is used as a nickel source; and the hydrogen production eletrocatalyst with NiV2S4 nanoparticles, uniform chemical composition and electrocatalytic activity in the whole PH electrolyte is obtained through one-step calcination after the constituents are uniformly mixed through a mechanical method. The preparation method has the advantages that the synthetic raw material is cheap, thesynthesis method is simple, the production cost is low, and the controllability is high. NiV2S4 is a novel aquatic cracking hydrogen production electrocatalyst that exhibits hydrogen production catalytic activity to a certain extent within the full pH range (0-14).

The invention provides a full-spectrum optical switch molecule as well as synthesis and application thereof. The optical molecular switch is a full-spectrum optical switch molecule designed and synthesized based on fluorescent matrixes such as naphthalimide and rhodamine, and can be used for excitation of 405nm, 450nm, 488nm, 560nm and 640nm. Intramolecular twisting is limited through azetidine, cyclobutylamide and other rigid structures, and the stability and brightness of the dye are greatly improved. The series of optical switch molecules do not need activation light, and only need monochromatic excitation light to realize reciprocating circulation from a dark state to a bright state of the molecules so as to obtain more accurate light spot positioning information. Molecules based on rhodamine dye have switch balance in a ground state, quenching of strong laser is not needed, and super-resolution imaging of cells can be achieved through mild laser. The dye provides full-spectrum novel photoswitch molecules, and has good application prospects in the fields of living cell super-resolution imaging, information storage and the like.

The invention provides a fluorescent dye for lipid droplet marking as well as a synthesis method and application of the fluorescent dye. The fluorescent dye is based on perylene bisimide. Two amino substituents are introduced into one electron donating group end for design and synthesis; the structural formula of the dye is shown as (1). Compared with commercial lipid droplet dyes, the light stability of the series of dye is greatly improved, and the fluorescence emission wavelength in different solvents reaches a near infrared region (680-730 nm), the brightness (phi) is greater than 0.4, thehalf-peak width (less than 60 nm) is narrow, and the biocompatibility is good. The fluorescent dye can be used for quickly and accurately dyeing lipid droplets in various living cells and oleaginousyeasts at low concentration. Besides, the fluorescence emission wavelength of the lipid droplet fluorescent dye in a triglyceride environment reaches 711nm, the tissue and living body penetrability ishigh, and the lipid droplet fluorescent dye has high biological applicability and can be widely applied to detection and imaging of lipid in a living body.