6results about How to "Excellent temperature sensitive performance" patented technology

The application provides an apatite structure silicate fluorescent powder, a preparation method thereof and application thereof in the field of optical temperature sensing, and relates to the technical field of fluorescent materials. z (SiO4)6O2:0.01Bi 3+ ,xEu 3+ ; 0 < x < 0.12, z = 8(1-0.01-x). The application adjusts Bi 3+ →Eu 3+ energy transfer by controlling Eu 3+ doping concentration in the Mg2Gd8(SiO4)6O2 matrix, realizes tuning of the fluorescent powder from blue light to red light, and particularly, the Bi 3+ →Eu 3+ energy transfer in the process of temperature rise and drop is beneficial to improving the temperature measurement sensitivity of the fluorescent temperature probe based on FIR, and realizes high-sensitivity optical temperature sensing (the maximum relative sensitivity reaches 0.92%K ‑1 (498K)). Meanwhile, the fluorescent powder can also be widely applied in the field of temperature visualization.

This invention relates to a mildly photothermal-releasing, injectable, self-healing hydrogel dressing for wound healing after oral cancer surgery. The hydrogel dressing is prepared by loading NO donor-loaded nanoparticles into a thermosensitive ABA triblock copolymer. This hydrogel dressing possesses thermosensitivity, injectability, self-healing properties, mild photothermal antibacterial activity, controlled NO release, blood compatibility, and biocompatibility. It can promote tissue regeneration, angiogenesis, and cell migration in postoperative wounds after oral cancer surgery, making it an ideal material for postoperative wound management in oral cancer patients.

The invention relates to a thermo-sensitive black phosphorus hydrogel (BP at Gel) for wound healing. The hydrogel is composed of a black phosphorus nanosheet loaded drug sulfadiazine silver and a chitosan thermo-sensitive hydrogel. The hydrogel has the temperature-sensitive characteristic, and can continuously release the medicine silver sulfadiazine under near-infrared irradiation, so that photo-thermal and antibacterial synergistic treatment is achieved. Meanwhile, the antibacterial effect on staphylococcus aureus is achieved. The thermo-sensitive black phosphorus hydrogel is a good wound dressing, and in a rat skin wound model, collagen deposition is promoted, new vessels are increased, and inflammatory factors are inhibited. The preparation method provided by the invention is simple to operate, and the hydrogel has thermosensitivity and good stability and biocompatibility, and can significantly improve the capability of promoting wound healing.

This invention discloses the preparation and application of radiofrequency thermoresponsive platinum ion crosslinked black phosphorus nanogel. The nanogel has a core-shell structure, comprising a core composed of a radiofrequency thermosensitive agent and chemotherapeutic drugs, and a shell constructed from a thermosensitive nanopolymer. The thermosensitive nanogel BP-Pt@PNA prepared using the above components exhibits radiofrequency thermosensitive properties. Simultaneously, the introduction of the thermosensitive nanopolymer improves the stability of the radiofrequency thermosensitive agent and chemotherapeutic drugs, enabling long-term drug retention and fully leveraging the synergistic effect of non-invasive radiofrequency thermotherapy and chemotherapy. This drug-loaded nanogel can achieve multimodal treatment applications, including non-invasive radiofrequency thermotherapy-chemotherapy synergistic antitumor therapy and invasive radiofrequency ablation-chemotherapy-vascular embolization synergistic antitumor therapy, demonstrating significant clinical translational potential.

The invention discloses a 3D printing cavernous body organ-like model capable of simulating an erectile physiological process, and belongs to the technical field of tissue engineering and regenerative medicine. The hydrogel is formed by photo-curing 3D printing of a dual-network hydrogel material formed by blending a pig cavernous body acellular extracellular matrix pregel solution and polyethylene glycol diacrylate, and has a bionic sine curve expansion structure; micron-sized grooves for guiding the directional arrangement of smooth muscle cells are formed in the surface of the micro-sphere, and an elliptical cavity for providing structural support is formed in the micro-sphere. A pig cavernous body dECM pre-gel solution is used as a base material, so that a microenvironment for living of cells in a body can be effectively simulated; by regulating and controlling the proportion of PEGDA, the mechanical property of the model is matched with that of a natural cavernous body tissue. The organ model can reproduce the NO-mediated smooth muscle cell relaxation and tissue expansion physiological process in vitro, and provides an effective in-vitro platform for researching the pathological mechanism of erectile dysfunction, screening drugs and developing a novel treatment method.

The present application belongs to the technical field of thermoelectric conversion, and particularly relates to a self-repairing thermoelectric hydrogel based on lignin, a thermoelectric conversion device, and a preparation method and application thereof. The present application successfully prepares a self-repairing thermoelectric hydrogel based on lignin by compounding specific inorganic small-molecule thermoelectric materials with cyclodextrin-modified lignin sulfonate and adamantane acrylate. In the formation process of the thermoelectric hydrogel, the inorganic small-molecule thermoelectric materials are uniformly dispersed in the network structure of the hydrogel, so that the hydrogel has excellent mechanical properties; the host-guest interaction introduced by the cyclodextrin-modified lignin sulfonate enables the hydrogel to have excellent self-repairing ability; the hydrogel also has good temperature sensitivity; the above characteristics greatly improve the thermal effect, thermoelectric conversion performance and electrochemical performance of the thermoelectric conversion device prepared based on the above thermoelectric hydrogel; and the preparation method of the above thermoelectric hydrogel is simple and easy to operate, the conditions are mild, the raw materials are easy to obtain, and the thermoelectric hydrogel has a wide application prospect.