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34 results about "Wound management" patented technology

Particle-form hybrid-scale fiber matrix

Particles of non-woven graft materials for use in specialized surgical procedures such as soft tissue repair and wound management procedures, methods for making the powder, and methods for repairing tissue such as neurological tissue using the powder are disclosed. The particles can advantageously be used to fill irregular shaped areas or can be used in conjunction with non-woven graft materials.
Owner:SOLVENTUM INTELLECTUAL PROPERTIES CO

Packaging box (wound treatment protective film)

ActiveCN310017304SDrug PackageChemistry
1. The name of the design product: packaging box (wound treatment protective film). 2. The use of the design product: the design product is used for the packaging of medicines. 3. The design points of the design product: the combination of shape, pattern and color. 4. The picture or photo that best indicates the design points: perspective view. 5. The design for which protection is sought contains colors. 6. The rear view is the same as the front view, and the rear view is omitted.
Owner:CHONGQING XINLINGFANG BIOPHARMACEUTICAL CO LTD

Biomass antibacterial hemostatic bandage and functionalization method thereof

The present application relates to the technical field of medical bandage, and discloses a biomass antibacterial hemostatic bandage and a functionalization method thereof.The bandage comprises a bandage base material and a composite antibacterial functional layer loaded thereon, the functional layer is composed of a composite antibacterial unit and lysozyme, and the composite antibacterial unit comprises a cationic antibacterial core, a polyphenol sustained-release shell and an enzymatic cellulose scaffold.The present application forms a biomass antibacterial hemostatic bandage with broad-spectrum, long-acting, low drug resistance and hemostatic function by constructing a cationic antibacterial core-polyphenol sustained-release shell-enzymatic cellulose scaffold composite antibacterial unit and synergistically loading lysozyme.The bandage shows significant technical advantages in dealing with complex wound infection, especially gram-negative bacterial infection and drug-resistant bacterial challenge, and provides an efficient and safe solution for clinical wound management, and has important clinical application value and broad market prospect.
Owner:YUNGUANG TECH (SHENZHEN) CO LTD

Preparation method and application of chitosan-based hydrogel wound dressing

PendingCN121819006ABandagesSmart hydrogelsWound dressing
The invention relates to the technical field of intelligent hydrogel dressings, in particular to a preparation method and application of a chitosan-based hydrogel wound dressing, and the preparation method comprises the following steps: integrating sulfydryl chitosan (CS-SH), carbon nanotubes (CNTs) and protocatechualdehyde (PA), and forming the chitosan-based hydrogel wound dressing through a crosslinking effect. The chitosan-based hydrogel wound dressing disclosed by the invention has the characteristics of photo-thermal performance, excellent antibacterial activity, excellent electrical conductivity, sensing performance and the like. The hydrogel wound dressing has great potential in the aspects of infectious wound treatment and real-time body action monitoring, and a new design thought is provided for developing an intelligent wound management system with specific adaptability to patients.
Owner:WUHAN UNIV OF SCI & TECH

A method of intervention in abnormal scarring of a caesarean section wound

PendingCN122369809AOperative woundTissue elasticity
This invention relates to the field of postoperative wound management technology, specifically to a method for intervening in abnormal scar hyperplasia after a cesarean section. The method includes the following steps: based on linear scar detection sites on the abdominal wall, the rebound temporal distribution characteristics are obtained; based on the changes in the rebound sequence, a segmented scar location structure is formed; the segmental nursing interval sequence is determined by combining the rebound arrangement relationship of each segment; nursing execution data is then generated according to the segmental location; and nursing rhythm changes are generated based on the differences in retesting. This invention calculates the recovery ratio based on displacement record changes and determines the rebound sequence to obtain temporal characteristics. By analyzing the internal temporal density, the order of segmental nursing is adjusted; the currently initiated segment is selected to optimize the application execution data; the records are rearranged to establish the nursing rhythm; and the unified treatment is transformed into a dynamic zonal intervention based on tissue elasticity. This eliminates the drawbacks of blind operation and ensures precise inhibition of tension concentration areas, comprehensively enhancing the targeted control of abnormal hyperplasia and improving the overall repair quality.
Owner:THE FIRST AFFILIATED HOSPITAL OF ARMY MEDICAL UNIV

Particle-form hybrid-scale fiber matrix

Particles of non-woven graft materials for use in specialized surgical procedures such as soft tissue repair and wound management procedures, methods for making the powder, and methods for repairing tissue such as neurological tissue using the powder are disclosed. The particles can advantageously be used to fill irregular shaped areas or can be used in conjunction with non-woven graft materials.
Owner:SOLVENTUM INTELLECTUAL PROPERTIES CO

Hydrogel powder loaded with bimetallic nano-enzyme and MG53 protein as well as preparation method and application of hydrogel powder

The invention relates to hydrogel powder loaded with bimetallic nano-enzyme and MG53 protein as well as a preparation method and application of the hydrogel powder, and relates to the technical field of biological medicines. PEG / SF hydrogel is used as a drug carrier, ZnCeO2 nano-enzyme and MG53 protein are encapsulated in hydrogel powder, and the problems that in-situ administration is prone to inactivation, controlled release is difficult and the like are effectively solved; the invention discloses a synthesis method of a ZnCeO2 nano-enzyme, zinc atoms are introduced to directionally regulate and control a complex catalytic reaction in the nano-enzyme, and released Zn < 2 + > can be combined with a specific binding site of MG53 protein, so that the activity of the MG53 protein is enhanced, and plateau wound healing is synergistically promoted. The hydrogel powder efficiently promotes plateau wound healing from inflammation control and tissue repair, provides a new thought for plateau wound dressing development, and also has important clinical significance on plateau wound management.
Owner:CHONGQING INST OF GREEN & INTELLIGENT TECH CHINESE ACAD OF SCI

Spectral-guided wound modeling and therapeutic dressing

ActiveUS12648879B1Image enhancementImage analysisCollagen scaffoldMedical treatment
A multispectral photonic imaging system and associated methods are disclosed for classifying wound tissue and generating customized therapeutic wound dressings. The system employs wavelength-specific optical sources and integrated image sensors to capture multispectral reflectance data from a wound, enabling computational classification of distinct tissue types such as granulation, slough, and necrosis. A three-dimensional (3D) digital model of the wound is constructed using spatial data from depth sensors. The classified 3D wound model facilitates automated design of patient-specific dressings, featuring heterogeneous regions tailored with therapeutic compounds like antimicrobial agents, analgesics, collagen scaffolds, and hydrogel matrices precisely aligned to corresponding tissue classifications. Additional imaging modalities, including thermal and ultrasound sensors, can be integrated to enhance classification accuracy and inform targeted therapeutic placement, providing a comprehensive and personalized approach to wound management for medical and veterinary applications.
Owner:UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION INC

A wet medical polyurethane foam dressing and a preparation process thereof

The application relates to the field of foam dressings, in particular to a wet medical polyurethane foam dressing and a preparation process thereof. The raw material scheme of the wet medical polyurethane foam dressing comprises polyurethane prepolymer, deionized water, a hydrophilic auxiliary agent, a chain extender, a gel catalyst, a foaming catalyst and a reinforcing agent and the like. The wet medical polyurethane foam dressing provided by the application has excellent comprehensive use performance. After absorbing a large amount of wound exudate, the dressing can still firmly lock the liquid under pressure, significantly inhibits the reverse osmosis phenomenon, and avoids the immersion damage of the skin around the wound. Meanwhile, the dressing has good flexibility and wet structure integrity, can be used in conformity with the wound contour, is not easy to adhere to the new tissue when being replaced, the stable long-acting liquid absorption capacity helps to prolong the replacement period, reduces the nursing workload and medical cost, and provides a more reliable and efficient solution for exudative wound management.
Owner:JIANGSU HONGSHENG BIOLOGICAL ENG CO LTD

Flexible electronic patch integrated with super capacitor film for wound management

The invention relates to the technical field of medical equipment, and discloses a flexible electronic patch integrated with a super capacitor film for wound management. The flexible electronic patch comprises a front-end device which comprises an organic electrochemical transistor and an electrical stimulation electrode, and a grid electrode of the organic electrochemical transistor is coated with drug-loaded DNA hydrogel; the flexible electronic system comprises a flexible electronic mainboard and a flexible super capacitor; the flexible electronic main board is electrically connected with the front-end device, and a near field communication module is integrated in the main board and is used for performing wireless communication with an external NFC reader-writer and providing wireless energy for the patch; the flexible super capacitor is electrically connected with the flexible electronic mainboard and the electrical stimulation electrode, and is used for storing the energy collected by the near field communication module and providing continuous electrical stimulation for the electrical stimulation electrode.
Owner:SUN YAT SEN UNIV

Intelligent disposable devices for wound therapy and treatment

ActiveGB2700130BMedical devicesMedical syringesSingle-Use DeviceMonitoring system
A disposable device 1000 for use with a wound treatment or monitoring system, comprising a substrate 500A (Figure 4A) or housing, and electronic circuitry at least partially supported by the substrate
Owner:SMITH & NEPHEW INC

An injectable self-healing hydrogel dressing, its preparation method and application

ActiveCN117643648BExcellent temperature sensitive performancegood injectabilityPharmaceutical delivery mechanismBandagesAntibacterial activityBiocompatibility
This invention relates to a mildly photothermal-releasing, injectable, self-healing hydrogel dressing for wound healing after oral cancer surgery. The hydrogel dressing is prepared by loading NO donor-loaded nanoparticles into a thermosensitive ABA triblock copolymer. This hydrogel dressing possesses thermosensitivity, injectability, self-healing properties, mild photothermal antibacterial activity, controlled NO release, blood compatibility, and biocompatibility. It can promote tissue regeneration, angiogenesis, and cell migration in postoperative wounds after oral cancer surgery, making it an ideal material for postoperative wound management in oral cancer patients.
Owner:SICHUAN UNIV

Rapid hemostasis and bandaging integrated device for wound

The invention relates to the technical field of wound treatment, in particular to a rapid wound hemostasis and bandaging integrated device which comprises a base, a winding box is fixedly connected to the top of the base, a winding rod is rotationally matched in the winding box, a bandage is fixedly connected to the surface of the winding rod and wound around the winding rod, and a traction opening is formed in the side wall of the winding box; shielding rings are symmetrically and fixedly connected to the winding rod, and first protruding blocks are fixedly connected to the shielding rings. Second protruding blocks are arranged on the shielding rings in a sliding fit mode, a plurality of springs are fixedly connected to the tops of the second protruding blocks, and the tops of the springs are fixedly connected with the inner top wall of the winding box. Through the design of the base and the winding rod, a bandage can be wound and rapidly fixed to the skin surface of a patient, automatic fixing of the bandage is achieved, rotation of the winding rod can be limited through the design of the first protruding block and the second protruding block, and therefore the tightening state of the bandage is guaranteed; a user can complete hemostasis binding operation with one hand, and the wound treatment efficiency is improved.
Owner:THE NAVAL MEDICAL UNIV OF PLA

Intelligent bionic dressing wound surface management system and method based on burns

The invention relates to the technical field of intelligent treatment, in particular to an intelligent bionic dressing wound surface management system and method based on burns, and the system comprises a wound surface observation module, a change recognition module, a wound judgment module, a medicine adjustment module and a remote joint control module. According to the method, a region and time two-dimensional data matrix is constructed through multiple types of sensing structures, temperature, humidity and pH parameters are continuously collected, formats are unified and standardized, a continuous monitoring data set with numbering index and time sequence characteristics is formed, an offset track is extracted based on a difference value sequence, a region with a clear change trend is positioned, and abnormal states are screened. The change amplitude, the growth rate and the offset direction are fused to realize condition judgment and path distinguishing of drug release, a behavior record set of a corresponding number is generated, a remote interaction log channel is established by combining parameter contrast data before and after a behavior, and state recognition refinement, intervention response autonomy, information feedback synchronization and process management closed loop are realized.
Owner:THE FIRST AFFILIATED HOSPITAL OF ARMY MEDICAL UNIV

Wound treatment system

Disclosed herein a wound care systems including an active layer and a foam layer. The wound care system can include one or more active agents, for example a QAS compound. In certain aspects, the wound care system includes K21.
Owner:KIMMERLING HOLDINGS GROUP LLC

Porous silicon nano biological glue as well as preparation method and application thereof

The invention discloses porous silicon nano biological glue as well as a preparation method and application thereof, and relates to the technical field of biomedical materials. The porous silicon nano biological glue comprises a water-based solvent and porous silicon particles uniformly dispersed in the water-based solvent; the intelligent tissue adhesive has the advantages of being good in biocompatibility, high in function integration level, simple and convenient in preparation process and the like, achieves the integrated function of bonding, repairing and monitoring on wounds, and has wide application prospects in the field of wound management as an intelligent tissue adhesive.
Owner:NORTHWESTERN POLYTECHNICAL UNIV

Wireless microfluidic smart bandage for efficient wound exudate management and analysis in human subjects

A wearable wound management system integrating a flexible microfluidic assembly and real-time electrochemical sensing to autonomously sample, transport, and analyze wound exudate. A Janus membrane, formed by selective deposition of perfluoroalkyl-functionalized silica nanoparticles and O2 plasma etching on a PET film, may collect fluid via its superhydrophobic wound-facing side and deliver it to a curved, wedge-shaped microfluidic channel that enhances capillary flow. Downstream, a graded PDMS micropillar array refreshes a sensing region by unidirectional fluid movement. A drop-on-demand inkjet-printed, CO2 laser-patterned flexible sensor patch may measure nitric oxide, oxygen, hydrogen peroxide, pH, temperature, and other relevant metrics. An encapsulated wireless electronic module may transmit health data for wireless monitoring. This system, combined with machine-learning analytics, may enable continuous, in situ monitoring and predictive wound classification, supporting proactive and personalized chronic wound care.
Owner:CALIFORNIA INST OF TECH

VSD intelligent regulation and control system and multi-mode wound surface management method

The invention relates to the technical field of wound surface negative pressure regulation and control, and discloses a vacuum sealing drainage (VSD) intelligent regulation and control system and a multi-mode wound surface management method. The system comprises a wound state monitoring module, a negative pressure dynamic adjustment module, a contraindication early warning module, a data fusion module and a decision engine module. The wound surface state monitoring module is used for acquiring percolate viscosity data through a piezoelectric sensor array and synchronously acquiring impedance spectrum signals under a porous silica gel VSD material and a biological semi-permeable membrane sealing layer; the negative pressure dynamic regulation module regulates a continuous and intermittent suction mode switching threshold value by means of a fuzzy PID (Proportion Integration Differentiation) algorithm according to the data; the contraindication early warning module identifies a tissue activity abnormal region and marks a risk level based on the impedance spectrum signal frequency domain characteristic difference; the data fusion module integrates multiple types of data into a multi-mode wound state matrix; and the decision engine module analyzes the matrix, outputs negative pressure parameter correction including a pressure gradient value, a mode switching interval and a single suction duration, adapts to wound surface changes in real time, and realizes intelligent regulation and control of negative pressure drainage.
Owner:THE FIRST AFFILIATED HOSPITAL ZHEJIANG UNIV COLLEGE OF MEDICINE

Programmed wound treatment device

The programmed wound treatment device comprises dressing and a packaging body for sealing the dressing, a sealing area of the packaging body prevents the dressing from making contact with an external space, a vulnerable structure is arranged on the packaging body, external force acts on the vulnerable structure to partially or completely break the packaging body along the vulnerable structure, and the broken packaging body is separated from the dressing wrapped by the packaging body. The exposed dressings are dressing wiping parts, the dressings still located in the remaining packaging body are dressing holding parts, the dressings are sealed by the packaging body at intervals, and the areas, corresponding to the dressings, of the packaging body are provided with vulnerable structures; a plurality of dressings with different properties are sealed in the packaging body at intervals in three directions or more than three directions and are arranged clockwise or anticlockwise in a programmed manner, and the arrangement sequence is one of cleaning dressing, disinfection dressing, wiping dressing and wound protecting dressing or cleaning dressing, disinfection dressing and wound protecting dressing.
Owner:ZHEJIANG BAICHUANG HEALTH TECH CO LTD

Platinum-doped composite hydrogel, preparation method thereof and wearable electronic device

This application relates to the field of materials technology, providing a platinum-doped composite hydrogel and its preparation method, as well as a wearable electronic device. The platinum-doped composite hydrogel of this application employs a one-step freeze-thaw crosslinking process, free of toxic reagents, with a simple and controllable process. The hydrogel uses polyvinyl alcohol and sodium lignosulfonate as the matrix, exhibiting excellent biocompatibility and good hydrophilicity. It can absorb wound exudate and maintain a moist healing environment, and can stably produce hydrogen even at low voltage. The wearable electronic device of this application uses this hydrogel as an electrode, offering good fit, non-invasive safety, and enabling non-invasive long-term wear and real-time monitoring of wound status, dynamically reflecting inflammation levels. Through closed-loop control, it automatically starts and stops electrocatalytic therapy, producing hydrogen on demand and avoiding excessive intervention. The device boasts high overall integration, portability, and ease of use, effectively promoting wound healing and suitable for long-term care of chronic wounds such as those caused by diabetes. It balances safety and practicality, achieving precise and intelligent wound management.
Owner:CHANGSHA LUSHAN MICRO-NANO TECH CO LTD +1

Active shrinkage hydrogel based on red light carbon dot photosensitizer as well as preparation method and application of active shrinkage hydrogel

The invention relates to the field of biomedical polymer materials, in particular to active shrinkage hydrogel based on a red light carbon dot photosensitizer and a preparation method and application of the active shrinkage hydrogel. The active shrinkage hydrogel is prepared from the following raw material components in parts by mass: 100 parts of N-alkyl substituted acrylamide and derivatives thereof; 10 to 30 parts of anionic polysaccharide; 0.5 to 2 parts of a bisacrylamide compound; 0.5 to 2 parts of a tertiary amine compound; 0.5-2 parts of a free radical initiator; and 1-200 parts of a red light carbon dot photosensitizer. The hydrogel disclosed by the invention can generate remarkable mechanical shrinkage in the interval of 32-40 DEG C and actively release a red light carbon dot photosensitizer, the released red light carbon dot photosensitizer efficiently generates active oxygen 1O2 under the irradiation of visible light, and the bacteriostasis rate on broad-spectrum pathogens such as staphylococcus aureus, escherichia coli and candida albicans is greater than 99%. The preparation method provided by the invention has the characteristics of simple and convenient process, low cost and suitability for large-scale production, and provides an intelligent, efficient antibacterial and healing-assisting dressing material for clinical wound management.
Owner:TECHNICAL INST OF PHYSICS & CHEMISTRY - CHINESE ACAD OF SCI

Infectious disease department nursing protection device capable of rapidly adjusting size

The invention discloses an infectious disease department nursing protection device capable of rapidly adjusting the size, belongs to the technical field of infectious disease departments, and aims to solve the problems that the wound treatment speed is increased and the wound treatment time is shortened only by disinfecting and then converting a treatment site, debridement treatment and foreign matter and necrotic tissue removal in the existing wound treatment. And respiratory tract cough and sneezing of patients in hospitals or droplets remaining in the air can become infection sources. Fixed adjustment is carried out through the supporting base plate and the positioning pushing piece, nursing of the elbow joint of a patient is adapted through the adjusting arch piece, and dirty liquid is collected through the box body; by means of an integrated mechanism of the collecting branch box, a series of debridement processes can be conveniently completed, treatment sites do not need to be converted, the wound treatment speed is shortened, displacement of a wound part during debridement treatment can be prevented, the device can adapt to body structures of different patients, fixing around the wound can be adjusted in size according to the figures of the patients, and the device is convenient to use. And rapid adjustment is facilitated, and adaptability is high.
Owner:FIRST PEOPLES HOSPITAL OF NANNING

Intelligent sensing dressing system for multi-mode wound state monitoring and active intervention

The invention discloses an intelligent sensing dressing system for multi-modal wound state monitoring and active intervention, which relates to the field of medical equipment and comprises a flexible multi-modal sensing layer, a microenvironment regulation dressing layer, an integrated flexible electronic control unit, a local intelligent terminal module and a cloud data platform. The system can collect wound pressure, temperature, pH value and blood flow parameters in real time, operate an artificial intelligence risk prediction algorithm to generate risk levels and nursing suggestions, and send intervention prompts when preset thresholds are reached. The cloud platform realizes data storage, trend analysis and risk alarm pushing, supports remote monitoring and cooperation, and improves wound management efficiency and healing quality.
Owner:TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH

Wireless integrated system for chronic wound infection monitoring and combined treatment

The invention discloses a wireless integrated system for chronic wound infection monitoring and combined treatment, and relates to the technical field of wearable bioelectronic equipment.The technical scheme is characterized in that parameters such as wound temperature, pH and metabolic markers are monitored in real time through multiple electrochemical sensor arrays; and combined treatment is realized by combining electric response hydrogel drug release and electric stimulation. The system has good biocompatibility and mechanical elasticity, chronic wound healing can be remarkably accelerated, and an innovative solution is provided for personalized wound management.
Owner:BEIHANG UNIV

Cancerous wound management system and method based on AI evaluation and QFD

The invention discloses a cancerous wound management system and method based on AI evaluation and QFD, and relates to the technical field of medical health and artificial intelligence crossing. The system comprises a data acquisition module, a QFD demand conversion module, an AI evaluation module, a multi-mode intervention module and a closed-loop adjustment module. The method comprises the steps of demand acquisition and sorting, QFD demand conversion, AI three-dimensional evaluation, multi-mode intervention and closed-loop adjustment. According to the method, the QFD methodology and the AI precise evaluation technology are combined, precise conversion from patient demands to quantifiable technical indexes is achieved, full-period closed-loop management is formed by combining multi-mode physical intervention and a multidisciplinary collaborative scheme, the pain points of disjunction of demands and technologies, extensive evaluation and single treatment in traditional cancerous wound management are broken through, and the method has the advantages of being high in practicability and good in application prospect. The treatment effect and the patient experience are remarkably improved, and the method is suitable for precise and personalized management of malignant tumor related cancerous wounds.
Owner:SHANGHAI MINHANG DISTRICT CANCER HOSPITAL

Negative pressure wound treatment device and method

Negative pressure wound treatment systems and methods for using such systems are described. Preferred embodiments facilitate closure of wounds by preferentially contracting to provide movement of tissue. Some embodiments may include a wound filler aggregate having a filler material and a wound contact layer.
Owner:T J SMITH & NEPHEW

Devices and methods for wound treatment

Devices and methods for wound treatment are disclosed. A chamber may define a treatment space having an interior engineered surface including a plurality of structures configured to provide pathways for the distribution of negative pressure and to exert mechanical stress on a wound. One or more tubes may be in fluid communication with the treatment space to facilitate the application of negative pressure, the introduction of therapeutic agents, and the removal of wound material. Therapeutic agents may be formulated with a gel, for example, a hydrogel, a hydrocolloid, alginate, methyl cellulose, gelatin or any other gels for sustained-release and enhanced usability. A wound fluid collection device including an absorbable material may interface with the wound treatment device to facilitate the collection and disposal of wound material.
Owner:NEW HORIZON INNOVATIONS LLC

Implantable port placement system including low-scarring exterior

A system and a method for streamlining the port placement process. The placement system can simultaneously form an incision, dissect tissue, create a tissue pocket of the correct size for the port being placed, and place the port subcutaneously. In an embodiment, the port includes tunneling features for creating a subcutaneous tissue pocket. In an embodiment, the insertion tool includes tunneling features for creating a subcutaneous tissue pocket. Further, the port includes a reinforced, concave septum that allows for a low overall profile of the port, while still capable of withstanding power injection. This results in reduced procedure times, reduced scarring, and minimized wound management.
Owner:BARD PERIPHERAL VASCULAR INC

Wireless microfluidic smart bandage for efficient wound exudate management and analysis in human subjects

A wearable wound management system integrating a flexible microfluidic assembly and real-time electrochemical sensing to autonomously sample, transport, and analyze wound exudate. A Janus membrane, formed by selective deposition of perfluoroalkyl-functionalized silica nanoparticles and O2 plasma etching on a PET film, may collect fluid via its superhydrophobic wound-facing side and deliver it to a curved, wedge-shaped microfluidic channel that enhances capillary flow. Downstream, a graded PDMS micropillar array refreshes a sensing region by unidirectional fluid movement. A drop-on-demand inkjet-printed, CO2 laser-patterned flexible sensor patch may measure nitric oxide, oxygen, hydrogen peroxide, pH, temperature, and other relevant metrics. An encapsulated wireless electronic module may transmit health data for wireless monitoring. This system, combined with machine-learning analytics, may enable continuous, in situ monitoring and predictive wound classification, supporting proactive and personalized chronic wound care.
Owner:CALIFORNIA INST OF TECH