148 results about "Infection sources" patented technology

The embodiment of the invention provides a disease prediction method, device, a medium and electronic equipment. The disease prediction method comprises steps: activity trajectories of multiple usersare acquired; if a patient diagnosed with an infectious disease appears in the multiple users, based on the activity trajectories of the multiple users in a predetermined time period, the position relationship between other users in the multiple users and the patient in each time point is determined; according to the position relationship between other users and the patient in each time point, thecontact degrees between other users and the patient are calculated; and target users with the contact degrees with the patient higher than a predetermined threshold are predicted as a high-risk diseased population. In the technical scheme provided by the embodiment of the invention, persons closely contacted with the infection source of the infectious disease (that is, the patient) are determinedthrough the position information of the user, persons at risk of infection can be further accurately determined, corresponding measures are taken timely, and the health control level of the user is improved.

The invention discloses a method for tracking infection sources and predicting trends of infectious diseases by utilizing mobile phone tracks. The method comprises the following steps: acquiring new infected person data from a disease control and prevention center to obtain new infected persons; acquiring mobile phone traffic data and related base station data of the new infected persons in periods of time before and after the attack; carrying out track visualized analysis on the mobile phone traffic data and the related base station data of the new infected persons on a geographic information system platform; and analyzing the high-danger areas and crowds with infectious disease transmission, and predicting the trends of the infectious diseases. According to the method disclosed in the invention, the mobile phone tracks of the new infected persons and the geographic information system are combined, so that the regions through which the infection sources pass and the environmental conditions of the regions can be rapidly and correctly judged, the high-danger areas and crowds can be determined and prevention and control measures can be adopted in time.

Methods and apparatus for the inactivation of infectious agents in, on or around a catheter residing in a patient's body cavity. The method comprises transmitting non-ultraviolet sterilizing electromagnetic radiation (EMR) substantially axially along an optical element in the catheter body. Through delivery of the sterilizing EMR to particular areas of highest infection, the present disclosure is able to inactivate the major sources of infection in catheters.

The invention relates to the public health technology field and discloses the prevention and control method of disease control and travel information interconnection. The method comprises the following steps of retrieving the historical data of local infected cases and the composition of environmental factors affecting the survival of a disease infection source, and fitting a grid risk map; determining a newly infected person as an infection source, and obtaining the travel information of the newly infected person in the period of time before attack; classifying and screening the travel information, excavating possible resident points, combining with spatial road network data and carrying out semantization on the possible resident points; comparing the possible resident points in step 3 with the risk map generated in step 1 to acquire a main suspicious point which is taken as a high probability occurrence point; adopting an association rule excavation algorithm or a string pattern excavation algorithm to excavate a motion pattern so as to predict a possible propagation trend; and according to the above result, intervening a high risk area. The trend of an infectious disease is predicted and prevention and control cost is reduced.

Antibiotics (Abx) are the world's most misused drugs. Antibiotics misuse occurs when the drug is administered in case of a non-bacterial infection (such as a viral infection) for which it is ineffective. Overall, it is estimated that 40-70% of the worldwide Abx courses are mis-prescribed. The financial and health consequences of Abx over-prescription include the direct cost of the drugs, as well as the indirect costs of their side effects, which are estimated at >$15 billion annually. Furthermore, over-prescription directly causes the emergence of Abx-resistant strains of bacteria, which are recognized as one of the major threats to public health today. This generates an immediate need for reliable diagnostics to assist physicians in correct Abx prescription, especially at the point-of-care (POC) where most Abx are prescribed. Accordingly, some aspects of the present invention provide methods using biomarkers for rapidly detecting the source of infection and administrating the appropriate treatment.

The invention discloses a computer virus monitoring system, which comprises a monitoring module, an antivirus engine, a control module and a rule base, wherein the monitoring module is suitable for monitoring file-based dangerous behaviors in computer equipment and calling one or more antivirus engines when the dangerous behaviors occur; the antivirus engine is suitable for judging whether a file corresponding to a dangerous behavior is a threatening file, acquiring characteristic information on the threatening file and calling the control module when the file corresponding to the dangerous behavior is the threatening file; the control module is suitable for receiving the characteristic information on the threatening file and extracting and returning a scanning strategy matched with the characteristic information on the threatening file from the rule base; and the rule base is suitable for storing the preset scanning strategy. According to the computer virus monitoring system, a virus infection source can be cut off from the source, and the propagation of infection type virus is timely prevented.

The invention discloses a computer virus monitoring method and device. The method comprises judging whether files corresponding to dangerous behaviors are threatening files or not when the dangerous behaviors based on the files occurring in computer equipment are monitored; obtaining feature information of the threatening files and sending the feature information to a control procedure on yes judgment; receiving the feature information of the threatening files through the control procedure and extracting a scanning strategy matched with the feature information of the threatening files from a preset scanning strategy; and returning the matched scanning strategy through the control procedure. The computer virus monitoring method and device can cut off a virus infection source from a source and timely prevent spreading of infection viruses.

The invention provides a detection reagent and a method for identifying a porcine pseudorabies virus vaccine strains and a wild strain, and belongs to the field of animal pathogen detection. The detection reagent comprises two primer pairs as shown in SEQ ID NO.1-4 and probes as shown in SEQ ID NO.5-6. The invention further provides a method for identifying a porcine pseudorabies virus vaccine strain gD gene and a wild strain gE gene by using the detection reagent. The porcine pseudorabies virus vaccine strains and the wild strain can be simultaneously identified through dual fluorogenic quantitative PCR, high-flux detection on large-scale samples can be achieved, the detection reagent has the characteristics of rapidness, specificity, sensitivity, accuracy, simplicity and convenience, provides an effective tool for surveying porcine pseudorabies infection sources and tracing infection environments and disease sources, and has relatively good application value in prevention and control on porcine pseudorabies.

The invention relates to a fluorescence PCR (polymerase chain reaction) detection method for diagnosing infection of Chlamydia trachomatis (CT), neisseria gonorrhoeae (NG) and ureaplasma urealyticum (UU), which belongs to the field of nucleic acid in vitro diagnosis. The method comprises a polymerase chain reaction (PCR) system based on fluorescence PCR technology, contains a forward primer and areverse primer aiming at the CT/the NG/the UU and a fluorescent probe, and can detects DNA of three pathogens such as the CT, the NG, the UU and the like simultaneously in a reaction tub under suitable PCR condition. The method can diagnosing the infection of the CT/the NG/the UU in a clinical sample simply, conveniently and rapidly, has high sensitivity and specificity, and has important clinical value to early control and prevention of relevant genitourinary tract infections, blocking of an infection sources, and infection reduction of related pathogen.

The present invention discloses a method for control of phytophthora blight of pepper by mixed application of trichoderma preparation and fungicides. The method comprises: seeding after mixing pepper seeds with the trichoderma preparation during seeding, or, applying the trichoderma preparation during pepper seedling transplanting and planting; during pepper cultivation, applying the fungicides before the occurrence of the disease or in early days of the disease; wherein the active strain in the trichoderma preparation is Trichodermaasperellum Thz01, and the preservation number thereof is CGMCC No. 6422; the fungicides are one or both of eugenol and mandipropamid. The trichoderma preparation used in the method of the invention has good control effect on phytophthora blight of pepper in the fields, and can effectively reduce the primary infection source when being used alone; while the additional application of the fungicides can effectively control disease epidemics. According to the method of the invention, the application amount of the fungicides is reduced, so residues of pesticides in the soil and pepper products are decreased, thereby ensuring environmental and product safety.

The invention belongs to the field of inspection and quarantine technology. Specifically, the invention is a nucleic acid detection reagent kit for synchronous discriminating and diagnosing avian influenza virus and newcastle disease virus. The detection reagents of the reagent kit include extraction reagent for extracting virus by silicon gel absorption column method, detection amplification reagent for detecting nucleic acid by RT-PCR Taq Man fluorescent probe method, and pretreatment liquid for solid tissue specimen for extracting virus RNA. Further, the invention employs in vitro transcription RNA as a positive contrast of the reagent kit. The reagent kit can rapidly and synchronously discriminate and diagnose avian influenza virus and newcastle disease virus which are highly infectious among avian plagues and have similar symptom, determine current major prevalent subtypes, such as H5, H7, H9, etc., and discriminate whether a infection source is an avian influenza having high pathogenicity, non-pathogenic avian influenza or mildly pathogenic avian influenza to human. The reagent kit is suitable for livestock and veterinarian station, import and export inspection and quarantine bureau, as well as other laboratories, and can be used for large-scale detection of influenza and epidemic surveillance.

The invention discloses a litopenaeus vannamei and fish mixed culturing ecological breeding method. A pond with brackish water is selected, during a slack winter season, spiral shell harm is removed, filiform algae are cultured in a directed mode, deposit phosphori in the pond bottom are adsorbed and removed, on around the Tomb-sweeping Day in spring, quick lime dry method pond poisoning is carried 20 days before culturing, 10 cm water adding is carried out before fry adding planning, bleaching powder is used for soaking a disinfecting tank bottom for 12 h, 80 cm water adding is carried out, after water adding is completed, oil tea cakes which are soaked by warm water for 24 h in advance are splashed, and organic fertilizer obtained through microbial fermentation is hung at the side of the pond. After water cultivating, young shrimps are subjected to out-of-cage breeding, after seven days, small-specification mixed-culturing fingerlings obtained after salinization are subjected to out-of-cage breeding, on the 35th day, large-specification mixed-culturing fingerlings are subjected to out-of-cage breeding, then the water level is deepened gradually, the water level is controlled to be 1.1 m-1.2 m, in the early period, feeding is carried out 2 times a day, in the medium-later period, feeding is carried out 3 times a day, computing is carried out according to 2%-8% of body weight, breeding is carried out for 80-100 days, and litopenaeus vannamei is harvested. Mixed fishes with the proper matched density are used for eliminating sick and weak shrimps, the infection source of sick shrimps is removed, prawn abnormal group swimming is avoided, sick shrimps are reduced, and the success rate of culturing is improved.

Antibiotics (Abx) are the worlds most misused drugs. Antibiotics misuse occurs when the drug is administered in case of a non-bacterial infection (such as a viral infection) for which it is ineffective. Overall, it is estimated that 40-70% of the worldwide Abx courses are mis-prescribed. The financial and health consequences of Abx over-prescription include the direct cost of the drugs, as well as the indirect costs of their side effects, which are estimated at >$15 billion annually. Furthermore, over-prescription directly causes the emergence of Abx-resistant strains of bacteria, which are recognized as one of the major threats to public health today. This generates an immediate need for reliable diagnostics to assist physicians in correct Abx prescription, especially at the point-of-care (POC) where most Abx are prescribed. Accordingly, some aspects of the present invention provide methods using biomarkers for rapidly detecting the source of infection and administrating the appropriate treatment.

The invention discloses a fluorogenic quantitative PCR detection reagent for FAdV-4TaqMan MGB and a preparation method and application of the fluorogenic quantitative PCR detection reagent. The fluorogenic quantitative PCR detection reagent comprises a pair of specific primers and a fluorescence probe. The nucleotide sequences of the specific primers are SEQ ID NO.1-2, and the nucleotide sequence of the fluorescence probe is SEQ ID NO.3. The aviadenovirus I subgroup C-race forth serotype virus (FAdV-4)TaqMan MGB fluorogenic quantitative PCR detection primers and probe and an FQ-PCR detection method established based on the primers and probe have the advantages of being fast, specific, sensitive, high in flux and the like, detection can be completed within 1 h to 2 h, and the requirement for large-batch and fast detection of aviadenovirus I subgroup C-race forth serotype viruses can be met. An effective tool is provided for fast detection, infection source surveying, transmission environment and pathogeny tracing of aviadenovirus, and great significance is achieved for prevention and control of the viruses.

The invention discloses a combined method of a stereo ecological polyculture mode and the prevention and control of hepatopancreatic necrosis disease and white spot syndrome. Specifically, 3 days before adding prawn seeds, 200 scatophagus argus fries with length of 3-5cm and 300 siganids fries with length of 2-3cm are added into every Mu of a breeding pond; when prawn seeds are to be added, a prawn seed addition amount is 80000-100000 seeds/Mu; when prawn length reaches 4-5cm, 5-6 Nile perch with length of 8-10cm and 10-15 hybrid giant tiger groupers with length of 8-10cm are added into every Mu of the pond. According to the invention, fishes with different feeding habits are cultured with prawns at a same time, such that diseases and weak prawns are eliminated in time, prawn disease infection source is eliminated, and a water cleaning function is realized. A polyculture mode of prawns and fishes with suitable specifications is started from a breeding early-mid stage, such that a prawn disease infection source is cut off, and hepatopancreatic necrosis disease and white spot syndrome outbreak is prevented. The breeding mode is optimized, such that prawn breeding success rate is improved. The method provided by the invention is suitable for the breeding of prawns such as litopenaeus vannamei, marsupenaeus japonicas, penaeus monodon and the like.

A network worm active hampering method based on driver checking and a confronting tool automatic generation system relate to the field of network security. The method and the system are used for improving the response speed to new worms, timely hampering spread of infection sources, eliminating the worms and the leaks of uncontrollable nodes and thoroughly eliminating the worms. The method is technically characterized by comprising performing packet capture detection by arranging a probe at the outlet of a network; when finding the infected host of worms, entering the infected target host through leaks and taking measures of searching and killing the worms, mending the leaks, immunizing the host and the like to achieve the aim of eliminating the network worms; meanwhile, scanning the host inside the network through a quick scan technology to achieve remote mending of existing leaks. The confronting too automatic generation system comprises a remote network worm eliminating tool analysis and automatic generation subsystem, a delivery tool analysis and automatic generation subsystem and an active mending patch analysis and automatic generation subsystem. The network worm active hampering method based on driver checking and the confronting tool automatic generation system can achieve a response speed to effectively hamper the worms in the spreading initial period of the worms.

The invention provides an intelligent terminal for hand hygiene compliance supervision. The intelligent terminal comprises a wearable terminal used for being worn on the human body and a signal projector which is used for being installed on a specific position of an inpatient ward; the wearable terminal comprises a main controller, a low-frequency sensing module, an attitude sensing module, a man-machine interaction module, an acoustic-optic alarming module and a power module, and the low-frequency sensing module, the attitude sensing module, the man-machine interaction module, the acoustic-optic alarming module and the power module are connected with the main controller; the main controller comprehensively judges whether personnel are in contact with an infection source or not or clean the hands or not according to information acquired by the low-frequency sensing module and the attitude sensing module, and gives out prompting information through the acoustic-optic alarming module according to the judgment result; meanwhile, personnel feedback information is received through the man-machine interaction module, the judgment result is corrected, and a judgment mechanism is improvedaccording to the correction result. By means of the intelligent terminal for the hand hygiene compliance supervision, mixed sensing technologies like low-frequency sensing and recognition, attitude sensing and infrared approach sensing are comprehensively adopted, and the executing situations of hand hygiene can be effectively monitored.

The invention discloses a transportable quarantine isolation ward comprising a quarantine consulting room, an isolation room, a power supply system, a water supply system, a sewage collecting and treating system and an air treating and discharging system, wherein the quarantine consulting room and the isolation room formed by plates in an enclosed manner are separated and have a shape and a size suitable for transportation, the sewage collecting and treating system is used to sterilize and disinfect discharged sewages and the air treating and discharging system is used to disinfect and discharge the air. The quarantine consulting room is provided with an apparatus for washing hands, an apparatus for storing quarantine articles, an apparatus for quarantine and diagnosis for patients in the isolation room, an intercommunication system for communication with the isolation room and an apparatus for storing dirts. The isolation room is provided with an apparatus for washing hands, beds for the patients, a transportable stool and an apparatus for storing dirts. The invention provides a transportable quarantine isolation ward which can be moved at any moment and is convenient and fast for quarantine, thus effectively isolating infection sources and controlling the propagation.

The invention relates to a collection box, in particular to a medical garbage collection box capable of isolating an infection source. The utility model relates to the medical garbage collection box,in particular to the medical garbage collection box capable of isolating medical garbage, preventing bacteria from flying out to cause infection of surrounding people, preventing people from seeing the medical garbage and avoiding discomfort. The medical garbage collection box capable of isolating the infection source comprises a bottom plate and a shell, one side of the bottom plate is fixedly connected with a collection barrel, and the collection barrel is used for collecting medical garbage; and the shell is placed on one side of the bottom plate. According to the medical garbage collectionbox, a pedal is treaded to move downwards, so that the right portion of a cover plate swings upwards to not block the top of the shell, meanwhile, a collecting frame rotates reversely to be in a horizontal state, people throw medical waste into the shell to fall into the collecting frame, the pedal is loosened, the collecting frame resets to pour the medical waste into a collecting barrel, and the cover plate blocks the top of the shell; and the situation that the bacteria on the medical garbage fly out to cause personnel infection is avoided.

The invention discloses a nucleic acid (DNA/RNA) real-time constant-temperature gene amplification detection method. The method is a rapid and efficient novel isothermal amplification detection method taking microplate reader detection as a core. The method particularly comprises the following steps that a to-be-detected sample DNA/RNR template is added into a 15 microliters-25 microliters of LAMP amplification system with certain neutral red concentration and then put into a microplate reader with the temperature ranging from 60 DEG C to 65 DEG C to detect change of absorbance of a reaction system in real time, and therefore the reaction is indirectly monitored. A reaction signal is expressed in the form of a curve, the curve enters a logarithmic phase within 30 min-60 min to express that a detected sample is positive, and the curve extends all the time but not enters the logarithmic phase to express that the detected sample is negative. The nucleic acid (DNA/RNA) real-time constant-temperature gene amplification detection method is simple, rapid and convenient, a great push function is achieved for subsequent basic-level popularization, compared with a traditional PCR detection method, rapid and safe detection of a gene is achieved, and an important significance in the aspects of blocking transmission routes, effectively controlling and tracking infection sources and effectively controlling outbreak and prevalence of superbacteria is achieved.

The invention discloses a light split-type peritoneal dialysis heat exchange heating system and a heating method, wherein the system comprises an isolating disinfecting operating compartment and a split-type intelligent heating compartment; medical latex gloves for left and right hands, which are fixed to two sidewalls, are arranged in the isolating disinfecting operating cabin; a compartment door, which can slide up and down, is arranged on the front wall of the isolating disinfecting operating cabin; three round holes are formed in the lower edge of the compartment door, so that a drainage bag pipeline, a solution bag pipeline and an external short pipe can be placed; an ultraviolet disinfecting lamp is arranged on the upper edge of the rear wall of the isolating disinfecting operating cabin; a heating panel is arranged at the bottom of the split-type intelligent heating compartment; a temperature-sensitive contact is arranged on the heating panel; an intelligent control panel is connected to the outside of the split-type intelligent heating compartment; a hook, which is used for hanging a peritoneal dialysis liquid bag, is arranged on the inner wall of the split-type intelligentheating compartment; and heat of the split-type intelligent heating compartment can be continuously preserved. The light split-type peritoneal dialysis heat exchange heating system provided by the invention is small in required operating space and short in duration in the operating compartment; infection sources are greatly reduced; peritoneal dialysis liquid heating and heat-preserving are integrated; and patient's life quality is improved.

The invention relates to a rapid pulse field gel electrophoresis typing method for streptococcus fish. The typing method takes streptococcus from separation and culture as an analysis sample, and comprises the following steps of gel piece preparation, cell lysis, gel piece washing, digestion of DNA (Deoxyribonucleic Acid) in a gel piece, sample feeding, electrophoresis and image acquisition in sequence, wherein the steps of gel piece preparation, cell lysis, gel piece washing, sample feeding and image acquisition are all implemented according to an ordinary pulse field gel electrophoresis method, and parameters are optimized; the water bath temperature in the gel washing is 50 DEG C; the digestion of the DNA in the gel piece is performed by SmaI enzyme; and in electrophoresis parameters, the voltage is 6V/cm, the corresponding pulse time is 10s-45s, the included angle of an electricity field is 120 degrees, the electrophoresis temperature is 14 DEG C, and the total electrophoresis time is 22h. The method has stronger classification capability on the streptococcus fish, and the time of a whole experimental process is shortened by 3 to 4 days, so that the method has great significance to monitoring of streptococcus fish diseases, infection source tracing, transmission route investigation and recognition and the like.

A portable device for collecting and sterilizing the flying saliva of SARS patient is composed of a face mask with air or oxygen inlet and air outlet connected to sterilizer via a tube, and a sterilizer consisting of disinfectant storage, coiled exhaust tube, and air-drawing fan installed in its exhaust outlet. Its advantages are simple structure and high effect on cutting off the infection source.

The invention discloses a cleaning device for a nursing surgical department. The cleaning device comprises a base. A connector is arranged on the base. A hydraulic rod cavity is arranged on the connector. A hydraulic cylinder, a hydraulic pump and a control cabinet are arranged on the base. The control cabinet is electrically connected with a hydraulic rod cavity, a piston rod, a hydraulic cylinder and a hydraulic pump through a control system. A temperature monitor is arranged on a baffle. An alarm device is arranged on the temperature monitor. The temperature monitor is adopted for performing temperature monitoring on a cleaning solution, and the phenomenon that a cleaning solution loses efficacy and scalds a patient due to the fact that the heating temperature is excessively high is avoided; a sewage tank and a garbage can are arranged, environmental pollution and infection source diffusion caused by random sewage drainage are avoided, the number of supporting legs is four, the bearing capacity is uniformly distributed, the service life of the cleaning device is prolonged, and the whole device is simple in structure and convenient to operate, has the high user-friendly design, and has the market promotion and application value compared with a traditional cleaning device with the single function.

The invention discloses a gene chip for detecting 15 clinical common pathogenic microorganisms. The gene chip comprises specific detection probes fixed on a solid phase vector, wherein the probes are designed for 16SrRNA gene and ITS gene sequences of staphylococcus aureus, klebsiella pneumoniae, pseudomonas aeruginosa, proteus mirabilis, Escherichia coli, shigella, enterobacter aerogenes, pseudomonas fluorescens, candida albicans, candida glabrata, candida tropicalis, candida parapsilosis, aspergillus terreus, aspergillus flavus and rhizopus oryzae, and screened and verified by repeated tests, and have high hybridization specificity and accuracy. The chip provided by the invention ensures simple detection operations and relatively lower cost, saves time, is applied to the screening of the clinical common pathogenic microorganisms, the early rapid diagnosis of critical patients and the diagnosis of suddenly occurring infection event pathogens and favorable for clinically rapidly diagnosing infection sources and functions in the early detection and early diagnosis of clinical diseases.

The present invention relates to a fluorescent PCR (polymerase chain reaction) detection method for diagnosing low risk type human papilloma virus (HPV) infection, belonging to the in vitro nucleic acid diagnosis field. The present invention comprises a multiple polymerase chain reaction (PCR) system based on fluorescent PCR technique, includes a forward primer and a reverse primer which aim at a plurality of HPV types, as well as a fluorescent probe, and can simultaneously detect DNA comprising six HPV types at most, namely HPV6, 11, 40, 42, 43 and 44, in one reaction tube under proper PCR conditions. The detection method can conveniently and rapidly diagnoss HPV infection in clinical samples, is high in specificity, and has great clinical value for preventing and controlling condyloma acuminatum in an early stage, blocking infection sources and reducing HPV infection.