12 results about "Infection type" patented technology

The invention relates to compound herba houttuyniae eye drops as well as a preparation method and application of the compound herba houttuyniae eye drops. Comprising the following preparation raw materials in percentage by mass: 1-6% of a herba houttuyniae extracting solution, 1-5% of an aglaia odorata extracting solution, 1-2% of a gelidium amansii extracting solution, 0.1-0.3% of acyclovir, 0.1-0.3% of tobramycin, 0.01-0.1% of dexamethasone sodium phosphate, 0.1-1% of sodium hyaluronate, 0.1-3% of glycerol and 88-93% of purified water. According to the compound herba houttuyniae eye drops prepared by the preparation method disclosed by the invention, the herba houttuyniae extracting solution, the aglaia odorata extracting solution, the gelidium amansii extracting solution, the acyclovir, the tobramycin and the dexamethasone sodium phosphate are combined for use, so that the compound herba houttuyniae eye drops have a relatively good curative effect on pets suffering from bacterium and virus mixed infection type conjunctivitis / keratitis; the compound herba houttuyniae eye drops are good in high-temperature-resistant storage stability and good in curative effect, the problem of frequent administration can be reduced, and the compound herba houttuyniae eye drops are more convenient to use and store.

The invention provides a kit and a method for identifying the infection category of a sample to be detected by detecting host peripheral blood gene expression, the kit simultaneously detects expression levels of two groups of genes in the sample to be detected, the first group is genes for identifying bacterial infection, the group of genes are S100P gene, ANXA3 gene, ITGAX gene and ITGAM gene, and the group of genes are S100P gene, ANXA3 gene, ITGAX gene and ITGAM gene. The first group is a gene for identifying fungal infection, the second group is a gene for identifying fungal infection, the group comprises an IFI44L gene, an IFIT3 gene, an IFIH1 gene, an LY6E gene, an IFIT1 gene and an IFITM3 gene, and whether the sample to be detected is bacterial infection, fungal infection, simultaneous bacterial and fungal infection or non-bacterial and non-fungal infection is determined by detecting the two groups of genes. According to the invention, ten genes expressed in peripheral blood are screened out, so that the detection cost and accuracy for distinguishing bacterial infection and virus infection can be kept at a balance point, and finally, clinical application can be realized.

A method of determining an infection type in a subject is disclosed. The method comprises measuring the concentration of a first determinant selected from the group consisting of the determinants which are set forth in Table 1 and a second determinant selected from the group of the determinants which are set forth in Table 2 in a subject derived sample, wherein the concentration is indicative of the infection type.

This invention belongs to the field of biological detection technology, and particularly relates to a reproductive tract HPV-mRNA-E6 / E7 detection system and method based on nanopore sequencing. The system includes a sample pretreatment module, an RNA extraction and purification module, a reverse transcription module, a nanopore sequencing module, and a bioinformatics analysis module. The method includes the following steps: (1) reproductive tract sample collection and pretreatment; (2) extraction and purification of HPV-mRNA in the sample; (3) reverse transcription of the purified HPV-mRNA into cDNA; (4) nanopore sequencing of the cDNA to obtain raw sequencing data; (5) filtering, comparing, and annotating the sequencing data through the bioinformatics analysis module to achieve HPV type identification and quantitative analysis of E6 / E7 gene expression levels. This invention utilizes the advantages of nanopore sequencing, such as long read length and real-time detection, combined with the specificity of E6 / E7 mRNA as a biomarker of active infection. It can directly detect latent and active HPV infection, improve detection sensitivity, accurately distinguish infection types, and shorten the detection cycle. It enables rapid, accurate, and high-throughput detection of active HPV infection in the genital tract, providing reliable technical support for early screening, disease monitoring, and prognostic assessment of HPV-related diseases such as cervical cancer.

The invention provides an infectious fever antibacterial scheme selection method and system based on multi-dimensional data, and belongs to the technical field of infectious disease diagnosis and treatment. The method comprises the following steps: step (1), identifying a fever type based on symptom and sign data and inspection data, and positioning a pathogen type, an infection site and severity; (2) generating candidate antibiotic schemes based on the antibiotic knowledge base and a guide rule engine; (3) adjusting the dosage according to the individual parameters of the patient, and generating a first scheme and an alternative scheme; through multi-dimensional data integration, infection types are rapidly identified, antibiotics recommended by a guide are matched, and an accurate and safe antibacterial scheme (including a first scheme and an alternative scheme) is generated according to individual conditions of patients.

The present application relates to the technical field of pest image analysis, and particularly relates to an AI image recognition and grading method for field crop leaf diseases and pests, comprising the following steps: under the irradiation of a fixed light source in a field, multiple polarized reflection images are synchronously collected at a predetermined angle interval around the crop leaves; a pixel polarization degree matrix of a leaf area in each polarized reflection image is extracted; the pixel polarization degree matrix is input into a polarization transmission model, and an abnormal cuticle coefficient map is output, and a region exceeding a preset abnormal threshold in the abnormal cuticle coefficient map is marked as a highlighted display region; an infection type template library is matched according to a distribution mode of the highlighted display region in the abnormal coefficient map; an infection intensity value is calculated in combination with a diffusion gradient of the highlighted region, and a disease and pest grade is output. The present application characterizes the optical mutation region boundary of a lesion area, not only improves the physical interpretation of disease detection, but also provides a distinguishable feature space for different infection mechanisms (such as a fungal growth layer and a pest piercing point).

The invention relates to the technical field of keratitis detection systems, in particular to a detection system for rapidly diagnosing keratitis. The invention provides a detection system for rapidly diagnosing keratitis, which comprises a kit and an excitation light source, the kit comprises three independently packaged reagent single tubes; the three reagent single tubes comprise a first reagent single tube, a second reagent single tube and a third reagent single tube which are arranged in sequence according to a medication sequence; a reagent in the third reagent single tube comprises 6PD-DPAN; reagents in the first reagent single tube and the second reagent single tube are independently DO-DPAS or M1-DPAN, and the reagents in the first reagent single tube and the second reagent single tube are different; and the lambda ex of the excitation light source is equal to 200 to 420 nm. The detection system can simply, conveniently, quickly and accurately detect the infection type of keratitis.

The application belongs to the field of biological detection, and particularly relates to sgRNA and RPA primer group, a detection system and application for synchronous detection of four pig-derived viruses. The sgRNA and RPA primer group for synchronous detection of four pig-derived viruses comprises sgRNA and RPA primer group for detecting porcine acute diarrhea syndrome coronavirus, porcine rotavirus, porcine transmissible gastroenteritis virus and porcine epidemic diarrhea virus. The application further provides a centrifugal microfluidic chip for synchronous detection of four pig-derived viruses, which can be used to synchronously and highly specifically identify multiple pig-derived viruses and accurately distinguish infection types in a single detection process, and the detection result has both laboratory-level sensitivity and accuracy.

This invention provides a kit and method for identifying the infection type of a test sample by detecting gene expression in host peripheral blood. The kit simultaneously detects the expression levels of two groups of genes in the test sample. The first group consists of genes for identifying bacterial infection, including the S100P, ANXA3, ITGAX, and ITGAM genes. The second group consists of genes for identifying viral infection, including the IFI44L, IFIT3, IFIH1, LY6E, IFIT1, and IFITM3 genes. Detection of these two groups of genes determines whether the test sample is infected with bacteria, virus, a combination of bacteria and virus, or neither bacteria nor virus. This invention screens out 10 genes expressed in peripheral blood, achieving a balance between the cost and accuracy of distinguishing between bacterial and viral infections, ultimately enabling clinical application.

The application discloses a bacillus mucilaginosus for inhibiting systemic infection type, pneumonia type and neurotype chicken pullorum salmonella and application thereof. The bacillus mucilaginosus for inhibiting systemic infection type, pneumonia type and neurotype chicken pullorum salmonella is named Anti-S.gallinarum, is preserved in the China Center for Type Culture Collection, and has a preservation number of CCTCC NO: M20251300.

A computer-implemented method determines an optimal drug dosing regimen to treat a patient against a drug-sensitive pathogenic agent responsible for infection. The method obtains patient data and drug data, including the drug, administration route, adaptation type (priori or posteriori), and a drug treatment regimen. The method includes determining values for pharmacokinetic parameters for efficacy (PPE) and pharmacokinetic parameters for toxicity (PPT) from the patient and drug data using population pharmacokinetic models when PPE and PPT are not obtained directly from measurement concentration(s). The method includes obtaining infection data, including parameters selected from the documentation of infection, localization, infection type, identified pathogen, susceptibility, and minimum inhibitory concentration. The method includes determining an efficacy target for the drug from the infection data and a target at risk of toxicity. The method includes determining an optimal dosing regimen by comparing PPE with the efficacy target and PPT with the risk of toxicity target.

The utility model relates to the technical field of plastic products, in particular to a dustproof and anti-infection type disposable plastic apron forming machine which not only can clean and sterilize a plastic film before hot cutting, prevent an apron from being polluted and improve the tidiness of the apron, but also can press the plastic film to prevent the plastic film from being damaged. The plastic film is prevented from wrinkling in the conveying process; comprising a protection mechanism; the device further comprises two sets of conveying mechanisms, a driving mechanism, a hot cutting mechanism, a discharging mechanism and a cleaning mechanism, the two sets of conveying mechanisms are both installed on the protection mechanism and conduct unwinding and winding on the plastic film, the driving mechanism is installed on the conveying mechanisms and drives the conveying mechanisms to conduct unwinding, and the hot cutting mechanism is installed on the protection mechanism and conducts hot cutting on the plastic film. The discharging mechanism is installed on the driving mechanism and drives the formed plastic aprons to be discharged, and the cleaning mechanism is installed on the protection mechanism and cleans and sterilizes the plastic films.