75 results about "Tissue specimen" patented technology

A method for removing a tissue specimen from a patient includes introducing a bag at least partially into a cavity in the body of the patient, the bag comprising an open end and a port, positioning a tissue specimen to be removed from the patient into an interior of the bag by passing the tissue specimen through the open end of the bag, sealing the open end of the bag, removing gas from the interior of the bag through the port while the tissue specimen is contained in the interior of the bag, and entirely withdrawing the bag containing the tissue specimen from the cavity. The bag may include a closure device configured to hermetically seal the open end of the bag, and the port may include a one-way gas valve configured to prevent or retard gas from entering the interior of the bag through the port.

A device(100) for immobilizing a tissue specimen or tissue specimens(900) for an automated embedder includes a base(120), a cover(130) and a frame(110). The base(120) has a cavity(121) configured to accommodate the tissue specimen or tissue specimens(900). The cover(130) is coupled to the base(120) and has an orientation structure(131) configured to orientate and secure the tissue specimen or tissue specimens(900) in the cavity(121) of the base(120). The base(120) and the cover(130) are detachably coupled to the frame(110). The orientation structure(131) includes a plurality of elastic ribs(1311) configured to provide a pressure on the tissue specimen or tissue specimens (900) and adjust the pressure according to a height of the tissue specimen(900) or heights of tissue specimens(900); and a flexible sheet(1313) coupled to the plurality of elastic ribs(1311) and having a plurality of flexible portions(13131) configured to contact and wrap the tissue specimen or tissue specimens (900) independently.

An apparatus for storing tissue and other biological materials includes a separable flexible container that includes a first layer coupled to a second layer via a set of seals to define a first storage volume and a second storage volume. Separate tissue specimens are containable within the first storge volume and the second storage volume. A first portion of the first layer or the second layer defines a first opening into the first storage volume. A second portion of the first layer or the second layer defines a second opening into the second storage volume. The opening into the first volume and the opening into the second volume are positioned near opposite edges of the flexible container. The separable flexible container also includes a hinge to allow the first opening and the second opening to move from location on opposing edges of the separable flexible container to adjacent locations.

A method for treating or diagnosing cancer with and endosurgical device comprising at least two lengthwise extending channels (2, 3, 4, 5; 2′, 3′, 4′, 5′), two opposite jaws (9, 10; 9′, 10′; 9″, 10″) with use of diathermy and flushing a tissue specimen to a proximal end of the endosurgical device. The method allows the surgeon to take several tissue specimens from an organ and to perform several functionalities when the device is inside the organ. The endosurgical device for use in the method is also disclosed.

The present application relates to the antibody of phorbolylated isocitrate dehydrogenase 1 and its preparation method and purpose, and specifically provides a polyclonal antibody, the polyclonal antibody is obtained by immunizing animals with the antigen epitope peptide of IDH1 phorbolylated, the specific site of the antigen epitope peptide is phorbolylated, and high-titer antibodies can be prepared, the phorbolylated modification of IDH1 in clinical specimens can be recognized with high specificity, and the polyclonal antibody can be used for the research of cell / tissue specimen immunoblotting and immunohistochemical method and the diagnosis of IDH1 related diseases.

Apparatus, systems, and methods are provided for localizing lesions within a patient's body, e.g., within a breast. The system may include one or more markers implantable within or around the target tissue region, and a probe for transmitting and receiving electromagnetic signals to detect the one or more markers. During use, the marker(s) are into a target tissue region, and the probe is placed against the patient's skin to detect and localize the marker(s). A tissue specimen, including the lesion and the marker(s), is then removed from the target tissue region based at least in part on the localization information from the probe.

Systems and methods for preventing the seeding of cancerous cells during morcellation of a tissue specimen inside a patient's body and removal of the tissue specimen from inside the patient through a minimally-invasive body opening to outside the patient are provided. One system includes a cut-resistant tissue guard removably insertable into a containment bag. The tissue specimen is isolated and contained within the containment bag and the guard is configured to protect the containment bag and surrounding tissue from incidental contact with sharp instrumentation used during morcellation and extraction of the tissue specimen. The guard is adjustable for easy insertion and removal and configured to securely anchor to the body opening. Protection-focused and containment-based systems for tissue removal are provided that enable minimally invasive procedures to be performed safely and efficiently.

An imaging well (100), comprising: an adhesive layer (110), and a liquid layer (120) covering the adhesive layer (110), the adhesive layer (110) and the liquid layer (120) forming a well body. The adhesive layer (110) is used for adhering a tissue specimen, the liquid layer (120) allows photons and liquids to pass through, and the well body accommodates an imaging liquid. The imaging well (100) allows specimen tissue to be adhered, and the operation process is simple and reduces tissue damage, thus significantly improving imaging stability and quality. In addition, the imaging well (100) can maintain the physiological state of tissues for a long time, and is suitable for long-time dynamic imaging research. Moreover, a stage comprising the imaging well (100), a two-photon microscope, and an imaging method are also provided.

Systems and methods for preventing the seeding of cancerous cells during morcellation of a tissue specimen inside a patient's body and removal of the tissue specimen from inside the patient through a minimally-invasive body opening to outside the patient are provided. One system includes a cut-resistant tissue guard removably insertable into a containment bag. The tissue specimen is isolated and contained within the containment bag and the guard is configured to protect the containment bag and surrounding tissue from incidental contact with sharp instrumentation used during morcellation and extraction of the tissue specimen. The guard is adjustable for easy insertion and removal and configured to securely anchor to the body opening. Protection-focused and containment-based systems for tissue removal are provided that enable minimally invasive procedures to be performed safely and efficiently.

A marking composition for marking a tissue specimen is provided. The marking composition includes a film forming resin including an acrylic resin, a rheology modifier including an associative polyurethane, a phyllosilicate, a cellulose, or a combination thereof, and a colorant. The composition has a viscosity of about 70 KU to about 110 KU at room temperature. If the composition includes a rheology modifier comprising cellulose, it is in an amount of about 0.01 wt % to about 0.25 wt % based on the total weight of the composition.

The present invention relates to the technical field of test chip preparation, specifically a method for preparing an immunohistochemical antibody quality test chip, comprising the following steps: S1, chip microarray design: selecting a variety of positive and negative tissue specimens to design 15 points; designing a 5×3 point tissue array; S2, collecting relevant wax blocks: selecting the required tissue wax blocks, and marking representative points in the paraffin specimens according to HE sections. This application clearly explains the operating method and the technical issues that need to be paid attention to during the operation, as well as the time and temperature that need to be controlled, so as to fully guarantee the quality of the corresponding staff during the operation to ensure the test effect. At the same time, this method can effectively increase the number of test chips during the test, and can effectively meet the screening of high-specificity, high-affinity antibodies.

The utility model discloses an intraoperative specimen collecting device for hysteroscopic surgery, which comprises a main pipeline, a sampling pipeline, a sampling pipeline, a sampling pipeline, a sampling pipeline, a sampling pipeline, a sampling pipeline and a sampling pipeline, and is characterized in that the main pipeline comprises a main pipeline body, and one end of the main pipeline body is connected with a suction pipe while the other end is connected with a negative pressure suction device; the collecting pipeline comprises a branch pipe body communicated with the main pipe body, and the free end of the branch pipe body is detachably connected with a negative pressure source; and the control valves are respectively arranged on the main pipe body and the branch pipe bodies and are used for controlling the main pipe body and the branch pipe bodies to be alternately connected and disconnected. According to the aspirator tube, abnormal tissue specimens reserved in the main tube body can be quickly and accurately transferred into a specimen container during an operation, the aspirator tube does not need to be repeatedly inserted and pulled, it is ensured that the specimens are accurately collected, and the specimens are prevented from being polluted or the operation environment is prevented from being polluted.

A marking composition for marking a tissue specimen is provided. The marking composition includes a film forming resin including an acrylic resin, a rheology modifier including an associative polyurethane, a phyllosilicate, a cellulose, or a combination thereof, and a colorant. The composition has a viscosity of about 70 KU to about 110 KU at room temperature. If the composition includes a rheology modifier comprising cellulose, it is in an amount of about 0.01 wt % to about 0.25 wt % based on the total weight of the composition.

The utility model relates to the field of pathological tissue specimen storage, in particular to a pathological tissue specimen storage box. According to the pathological tissue specimen storage box, the placement box can be rapidly limited and fixed, the situation that pathological tissue specimens overflow due to the fact that the placement box is opened is avoided, and the fixing mode is rapid and convenient. A lesion tissue specimen storage box comprises a storage cabinet, a sealing door, temperature control boxes and the like, the left front portion of the storage cabinet is rotationally connected with the sealing door, and a plurality of temperature control boxes are connected into the storage cabinet. The rotary knob is rotated to drive the rotary disc to rotate, so that the extrusion frame moves along the sliding rail on the rotary disc, the extrusion frame synchronously moves outwards to make contact with and extrude the limiting frame, the limiting frame is driven to move outwards, the limiting frame makes contact with the upper portion of the containing box, and the containing box can be rapidly limited and fixed; the pathological tissue specimens are prevented from overflowing due to opening of the placing box, and the fixing mode is fast and convenient.

The utility model provides a tissue specimen fixing device which comprises clamping pieces, the clamping pieces are bent to form a clamping space to clamp tissue, or two sets of clamping pieces are arranged, and the two sets of clamping pieces are located on the two sides of the tissue respectively and used for clamping the tissue; the fixing mechanism is installed on the clamping pieces and used for fixing the clamping pieces on the two sides of the tissue, the tissue is clamped and fixed through the clamping pieces, the clamping pieces play a role in shaping, the tissue is flattened, cells of the tissue are made to be relatively compact, the slicing effect of the soaked tissue is improved, and the tissue is not prone to damage. The fixing mechanism is used for fixing the clamping pieces, the tissue is prevented from falling off from a clamping space formed by the clamping pieces, and the stability of tissue fixing is improved; by using the fixing mechanism and the clamping pieces, the weight of the tissue can be increased, the tissue is completely soaked in the soaking liquid, the problem of tissue floating is solved, and the tissue soaking effect is improved.

A device and method for preparing frozen tissue specimens are disclosed. The device includes a solid block having a top surface and a bottom surface, with two parallel side walls extending upward from the top surface. A slotted groove is formed in the middle of the solid block and extends from the top surface to the bottom surface to receive a specimen chuck, such that a head of the chuck rests on the top surface. Top edges of the side walls support a tissue slide containing an encapsulated specimen. The device may include finger grooves for manual handling and is preferably made of a heat-conducting material to assist in rapid freezing. The method involves placing the specimen chuck in the groove, depositing a freezing medium over it, and positioning the tissue slide so that the specimen contacts the freezing medium for effective specimen preparation.

The invention provides a specimen image generation method based on endoscope shooting and an endoscope. The method comprises the following steps: acquiring a first category of images; wherein the first class image is used for indicating an image acquisition end of an endoscope to shoot an image acquired by a specimen in vitro; based on a preset distortion correction algorithm, distortion correction is carried out on the first type of images to obtain distortion correction images, and the distortion correction algorithm is an algorithm used for carrying out distortion correction on the first type of images; and storing the distortion correction image as a specimen image. By means of the method, the hardware cost can be effectively reduced, the problems that in the treatment process of organ or tissue specimens cut by an endoscope, the flow is complex, and shooting is delayed are solved, meanwhile, distortion correction is conducted on the in-vitro shot images, the images can be displayed according to the normal proportion, and the observation and recording effects of a user are improved.

The invention relates to the technical field of tissue specimen preservation, in particular to tumor specimen auxiliary storage equipment for tumor surgery. The device comprises a base, the top of the base is rotationally connected with an adjusting sealing cover, a low-temperature cavity is defined by the interior of the adjusting sealing cover and the top of the base, and the top of the adjusting sealing cover communicates with an air inlet; when the tumor specimen in the low-temperature cavity is taken out, the top of the side, away from the axis, of the specimen temporary storage piece is in sliding fit with the inner bottom wall of the sealing block, it is ensured that the space size of the buffer cavity is gradually reduced, and it is ensured that the upper portion of the buffer cavity is always kept sealed, so that a positive pressure space is formed in the buffer cavity; cold air originally coming from the low-temperature cavity in the inner part is discharged from an opening which is opened due to the rising of the sealing block; when a new clinical tumor specimen is stored in the low-temperature cavity, external air in a buffer cavity space below the low-temperature cavity is driven away through the downwards-pressed sealing block.

An image display device comprising a processor, in which the processor is configured to acquire a plurality of specimen images in which tissue specimens of a subject provided for an evaluation test of a candidate substance of a drug are imaged, receive designation of a criterion for setting a display priority of the plurality of specimen images from a user, set the display priority in accordance with the designated criterion, and perform control of displaying the plurality of specimen images on a display unit in accordance with the set display priority.

A computer-implemented method is provided of analysing an image of a tissue specimen, which method comprises steps including detecting in the image each of a primary type of biological entity, detecting in the image one or more secondary types of biological entity, associated with each of the detected primary biological entities, generating an entity graph, in which each graph node is assigned to a primary biological entity, and in which each graph node is associated with predictive features measured from the image in respect of that graph node, including at least one predictive feature that is measured relative to two or more types of biological entity.

The invention discloses an oral cancer in-vitro tumor tissue specimen treatment device, which comprises an adjusting part, a storage box, a first driving part arranged in the storage box, a second driving part arranged on the first driving part, and a tumor tissue specimen moving part, the sorting part comprises a placing part mounted on the second driving part, a cutting part and a dip dyeing part, the cutting part and the dip dyeing part are mounted in the placing box, and the tumor tissue is primarily sliced, dyed and observed through the sorting part; the pushing part comprises an upper edge part arranged on the placing part, auxiliary parts installed on the upper edge part and the storage box, and a flat paving part arranged on the auxiliary parts, the pushing part is used for promoting treatment of slices before staining of the tissue specimen, and the integrated treatment process of specimen moving, slicing, staining and observing is achieved; external pollutants are prevented from causing damage to the section, and the diagnosis accuracy is prevented from being influenced.

Components, systems and kits for capturing and removing tissue from mammalian bodies include a tissue container that may be introduced into a body cavity and within which a tissue specimen may be placed, cut and removed from the body cavity. Methods of using these components, systems and kits are also described.

A tissue removal device (20) is provided, comprising: a removal bag (30) having an opening (32) for receiving a resected tissue specimen (22) within a patient's body (24). An electrosurgical cutting wire (34) includes a cutting segment (36) and a pulling segment (40), the cutting segment (36) being detachably coupled to a wall (38) of the removal bag (30), and the pulling segment (40) being not connected to the wall (38) and extending out of the opening (32). The cutting segment (36) is wound around the central longitudinal axis (46) of the removal bag (30) at different locations along the central longitudinal axis (46). While the resected tissue specimen (22) is within the removal bag (30), the pulling segment (40) is pulled during the application of RF electrosurgical power, causing a plurality of successive longitudinal portions of the cutting segment (36) to separate from the wall (38) and cut the resected tissue specimen (22) within the removal bag (30). Other embodiments are also described.

1. Name of the product in this design: Pathological Tissue Dehydration Basket. 2. Purpose of this design: This product is used as a device for dehydrating pathological tissue specimens. 3. The key point of the design of this product lies in its shape. 4. The image or photograph that best illustrates the design's key points: 3D rendering 1.

A tissue removal apparatus (20) is provided that includes a retrieval bag (30) having an opening (32) for receiving a resected tissue specimen (22) within a patient's body (24). An electrosurgical slicing wire (34) includes a slicing segment (36) detachably coupled to a wall (38) of the retrieval bag (30), and a pulling segment (40) free of the wall (38) and extending out of the opening (32). The slicing segment (36) winds around a central longitudinal axis (46) of the retrieval bag (30) at varying locations along the central longitudinal axis (46). Pulling the pulling segment (40), during application of RF electrosurgical power when the resected tissue specimen (22) is within the retrieval bag (30), detaches successive longitudinal portions of the slicing segment (36) from the wall (38) and slices the resected tissue specimen (22) within the retrieval bag (30). Other embodiments are also described.

The utility model relates to the technical field of specimen bags, and discloses a specimen bag for fixing lung tissue specimens. The specimen bag for fixing the lung tissue specimen comprises a specimen bag body, a first attached lug is arranged on the left side of the specimen bag body, second attached lugs which are symmetrically distributed front and back are arranged on the right side of the specimen bag body, and the second attached lug on the rear side is movably connected with a pull rope penetrating through the first attached lug and the second attached lug on the front side. The device has the advantages that the operation is simple, special equipment is not needed, the popularization and application of the pathology department of a grassroots unit are easier, the market application prospect is wide, the economic value is very good, and the like. The problem that the existing tissue specimen bag used in the pathology department cannot solve the problem that the lung tissue specimen floats when being fixed is solved.

The utility model belongs to the technical field of medical instruments, and particularly relates to a standardized rapid pathological sampling device which comprises a knife handle, a square blade is connected to the lower portion of the knife handle in an embedded mode, a first bolt is connected to the lower portion of the right side of the knife handle in a threaded mode, and a second bolt is connected to the lower portion of the left side of the knife handle in a threaded mode. The square blade is fixedly connected with the cutter handle through a first bolt and a second bolt; according to the utility model, a tissue specimen in a square cutter shape can be obtained at one time by adopting the square blade, rapid pathological sampling can be realized, the size of the sampled sample is uniform and standard, and meanwhile, the cutter head is convenient to clean and cross contamination is prevented.

The system provides a method for surgically removing tissue through small incision sites and / or body openings. [Solution] The tissue containment and containment system includes a primary chamber, and a secondary channel extending from this primary chamber is interconnected with the primary chamber. A tissue specimen is placed into the primary chamber through a first opening 12 while floating in a body cavity. The first opening is drawn in through a first incision or body opening, and a narrower secondary channel is positioned at a second incision or body opening. A second opening 14 provided at the end of the secondary channel allows observation of the tissue specimen in the primary chamber, which is being cut through the first opening, by a scope inserted through the secondary opening. Other systems and methods are provided for sealing the second opening to create a closed system that enables deployment, containment, volume reduction, and safe retrieval of the tissue specimen.

A method for detecting conjunctival diseases such as conjunctival MALT lymphoma, and an aging biomarker that serves as an indicator of the aging state of a subject are provided. The method for detecting conjunctival diseases comprises a step of comparing a microbial community structure of a microbiota in an ocular surface tissue specimen sampled from a healthy person with a microbial community structure of a microbiota in an ocular surface tissue specimen sampled from a subject to determine that the ocular surface tissue specimen of the subject has an indication of the conjunctival diseases. The aging biomarker comprises bacterial species which belongs to the Corynebacteriaceae family or the Propionibacteriales family in an ocular surface tissue.

An image processing apparatus comprising a processor, in which the processor is configured to acquire a specimen image in which a tissue specimen of a subject provided for an evaluation test of a candidate substance of a drug is imaged, and perform image processing on the specimen image in accordance with a type of a source organ of the tissue specimen and / or a type of a morphological abnormality estimated to have occurred in the tissue specimen.