14 results about "Tissue Processing" patented technology

A tissue holder assembly includes: a base comprising a bottom member, a central hub extending upwardly from the bottom member, and a circumferential sidewall extending upwardly from the bottom member radially spaced apart from the hub, the circumferential sidewall surrounding the hub and defining an interior region configured for accommodating a cylindrical tissue holder; the base further comprising a raised platform spaced upwardly apart from the bottom member, the central hub extending through a central opening of the platform and configured for supporting the tissue holder; the bottom member, the hub, and the circumferential sidewall collectively defining an annular fluid channel underlying the platform; wherein the fluid channel extends around the hub from an opening in the platform to a fluid exit port in the circumferential sidewall; the base further comprising a flow comb underlying the platform opening and extending into the fluid channel.

A device includes a handle having a trigger in combination with a distal portion, the distal portion including a rigid elongated hollow member which receives tissue therein and a plunger fitted with and configured to slide longitudinally within the hollow member to induce suction at a distal end of the hollow member as the plunger is moved proximally within the hollow member. The trigger is hingedly coupled to the plunger so that pulling the trigger slides the plunger proximally with respect to the hollow member to generate suction to draw the tissue into the distal end of the hollow member. The device further includes a tissue treatment mechanism for encircling the tissue received at the distal end of the hollow member.

A uniquely identifiable consumable product for use in a histology or cellular pathology process for processing a biological sample from a source, the consumable product having a unique identifier which is not linked to the source of the sample is provided. By applying a unique identifier to cassettes and other consumable products prior to use, laboratory printers for printing identification information on tissue processing cassettes and on microscope slides and the like are redundant. The unique identifier is then linked to information relating to the sample to be analysed and its source. The physical process of applying a unique identifier to the consumables prior to use enables the decoupling of the physical printing of the consumable from information relating to the source of the sample obviates the need for provision of a printing capability for consumables in laboratories.

The invention discloses a method for observing the shape and number of synapses in a dentate gyrus region based on image analysis, and relates to the technical field of neurobiology. The method comprises the following steps: S1, tissue treatment: after an experimental animal is anesthetized, pouring a buffer solution and a stationary solution into the heart in stages, separating hippocampus tissue, trimming and fixing, pre-cooling, slicing and preserving at low temperature; s2, dyeing and marking: performing targeted marking on the dentate gyrus area of the sea horse by adopting DiI particles through a fine tungsten steel through needle, and preserving at low temperature after incubation; s3, fixing and mounting: fixing for the second time, and mounting with an anti-fluorescence quenching agent after DAPI nuclear dyeing; s4, confocal imaging is carried out, exclusive parameter layer scanning is set, and qualified dendritic spine images are screened; and image quantitative analysis can be further carried out, and accurate quantification is realized according to classification standards. The method is standard in operation, greatly improves sample quality and experimental result credibility, optimizes experimental efficiency and controllability and reduces technical threshold by means of targeted marking and standardized processes, and is suitable for relevant basis and application research of the hippocampal synapses.

This invention discloses a high-frequency ultrasound method for processing large-volume tissues. The method includes the step of placing biological tissues under high-frequency ultrasound conditions for processing. In the high-frequency ultrasound processing, the ultrasound frequency is 1 MHz, the sound intensity is 0.6 W / cm², and the temperature is 4℃. This invention also includes a high-frequency ultrasound system for processing large-volume tissues, characterized in that the system comprises a sample container or sample carrying platform module, a signal generation module, a power amplification module, an ultrasound transducer module, a temperature control module, and a circulating fluid circuit module. The high-frequency ultrasound method of this invention can be applied to the overall staining, tissue clearing, and resin embedding of large-volume tissues to improve the efficiency of the processing solution penetrating deeper into the tissue, improve the uniformity of internal and external tissue processing, and enhance the applicability of this method to fluorescent samples, thus possessing greater scalability and application value.

A system for administering medical procedures to patients is provided. [Solution] The system includes at least one of an energy delivery device, a long-term energy delivery device, and / or a power supply device. In particular, the system may be configured to treat and / or diagnose patients suffering from sleep apnea. Methods and apparatus for treating sleep apnea and other medical conditions are also provided.

A tissue treatment system (100) for providing a cold plasma treatment. A pulser (102) is configured to deliver in use a set of high-voltage pulses (Pp) to a plasma pad (101) for generating cold plasma of a pre-determined intensity. The pulser comprises a pulse modulation circuit (20) for controlling pulse width and / or pulse repetition frequency of the set of high-voltage pulses (Pp). A geospatial unit (103) is configured to determine geospatial information (M) of the pulser (102). A feedforward controller (104) is configured to perform a initialization of the pulser (102) prior to delivering the set of high-voltage pulses (Pp). The initialization comprises setting the pulse width and / or the pulse repetition frequency of the set of high-voltage pulses (Pp) based on a pre-determined relationship between the geospatial information (M) and the pre-determined intensity for generation of cold plasma that is substantially the same as at the sea level.

A tissue holder assembly (300) for receiving and imaging severed tissue samples from a biopsy device includes a base (240) and a cover (302) removably attached to the base to define an interior, the base having one or more vacuum lumens (208,224) in communication with the interior, the assembly further including a tissue tray (18) removably and rotatably mounted in the interior, wherein a bottom of the tissue tray comprises a filter material (24) that allows fluid to pass through. The cover has a tissue sample entry port (42) formed therein and configured direct severed tissue samples and fluid aspirated therethrough into a respective tissue storage compartment of the tissue tray positioned under the tissue sample entry port, wherein the base includes a raised surface (202) underlying at least a portion of the tissue tray circumferentially spaced apart from the tissue sample entry port when the cover is attached to the base.

X-ray images generated by a biopsy tissue handling apparatus are selectively modified to emphasize areas of interest and deemphasize or eliminate image areas that are distracting, impair view attention and / or contribute to eye fatigue, An image processor executes image masks based on a geometric configuration of a portion of a specimen tray including a storage compartment with tissue specimen, A compartment mask executes on a portion of X-ray image depicting storage compartment including tissue specimen. Compartment mask boundary substantially corresponds to a contour of compartment. Partial structure mask executes on a portion of X-ray image depicting respective walls of specimen tray and storage compartment. Partial structure mask boundary extends along respective lengths and partially through respective walls of specimen tray.

1. Name of the design product: tissue processing tube. 2. Use of the design product: container for biological sample tissue processing. 3. Design points of the design product: in shape. 4. Picture or photograph best indicating the design points: perspective view 1. 5. Other circumstances or explanations: the product in part A of perspective view 1 is made of transparent material.

This invention discloses a tissue stacking machine capable of stably folding tissues in half, comprising a frame and a tissue processing mechanism, a first half-insertion device, a second half-insertion device, a paper-supporting lifting device, a paper-pushing device, a paper-discharging device, a two-finger device, and a single-finger device mounted on the frame. In this invention, by setting the first and second half-insertion devices to partially insert into the paper feed path, the contact between the devices and the arched portion of the tissues output by the tissue processing mechanism is effectively reduced, thereby significantly lowering the probability of damage to the tissues during operation. Furthermore, when the paper-supporting lifting device transports the tissues to the paper-pushing device, the first and second half-insertion devices can support the tissues instead of the paper-supporting lifting device. Additionally, this invention uses the two-finger and single-finger devices for folding the tissues in half at the ends of the tissue stack, resulting in low requirements for coordination with other devices and a high success rate in folding in half.

This application relates to the field of biological tissue processing equipment technology, and discloses a closed-loop, high-efficiency tissue mincing device for extracting primary cells from chicken embryos. The device mainly includes a support frame, a cup body, a cooling box, a shearing assembly, and a sealing assembly. The shearing assembly is driven by magnetic coupling, with an external motor rotating a disk, which in turn drives a magnet at the bottom of the cup body to rotate a rotating shaft and moving blades. This creates an alternating shearing action with stationary blades fixed to the inner wall of the cup body, achieving uniform and efficient physical fragmentation of the chicken embryo tissue. The cooling assembly includes a cooling jacket surrounding the cup body and a circulating cooling system, effectively removing heat generated during the shearing process. The sealing assembly consists of a top cover, a sealing gasket, and a feed pipe with a sealing plug, ensuring a completely sealed operation. This invention solves the problems of significant mechanical damage to cells, easy thermal inactivation of samples, and the risk of contamination during open operation in existing technologies. It has the advantages of good cell morphology preservation, high biosafety, and convenient operation.

This invention provides a bipolar electrocoagulation device with suction function, comprising: a handle; a guide tube detachably mounted on the handle, with electrocoagulation forceps hinged inside the guide tube; a traction mechanism mounted inside the handle, the traction mechanism including a traction column slidably mounted inside the handle; and a suction mechanism mounted inside the handle, the suction mechanism including a suction box and a first sealing plate, the suction box being fixedly mounted on the handle, and the first sealing plate being slidably mounted inside the suction box. This invention solves the technical problem in the prior art where, to cope with smoke interference, bipolar electrocoagulation forceps are typically used in conjunction with a suction device. This requires medical personnel to operate the bipolar electrocoagulation forceps with one hand for tissue processing and independently operate the suction device to absorb the smoke with the other hand. In the stressful surgical environment, this requires a high degree of coordination between both hands, placing stringent demands on the medical personnel's bimanual coordination ability, increasing operational difficulty, fatigue, and the risk of error.