75 results about "Multiwell plate" patented technology

The invention discloses a flow intensity regulation and control device, a flow intensity regulation and control method and a laser proton accelerator. According to the device, a beam positioning sub-device is connected with a flow intensity adjusting and controlling sub-device, and the beam positioning sub-device is used for arranging the flow intensity adjusting and controlling sub-device in a vacuum cavity of the laser proton accelerator and adjusting the position of the flow intensity adjusting and controlling sub-device in the vacuum cavity; the flow intensity regulation and control sub-device comprises a movable perforated plate, a fixed perforated plate and a flow intensity regulation and control module; the movable perforated plate and the fixed perforated plate are overlapped and have the same shape, size and through hole arrangement; and the flow intensity regulation and control module is used for regulating and controlling the one-way relative displacement of the movable perforated plate and the fixed perforated plate so as to change the flow intensity regulation and control state of the flow intensity regulation and control sub-device on the laser proton beam. According to the embodiment of the invention, the beam flux can be rapidly and accurately adjusted, and the flow intensity of the proton beam can be rapidly and accurately adjusted.

The present invention concerns systems, materials, and methods of cell, cell organelle and / or particle separation and / or concentration utilizing magnetic levitation to affect separation. In some embodiments, the separation and / or concentration is performed in the wells of a multi-well plate.

A device for CO2 microbubble flooding comprises a microbubble generating device, a stirring and liquid storage device, an injection pump, a gas compressor, a gas-liquid mixer and a pressure stabilizing system, wherein the microbubble generating device adopts an integrally formed multi-layer cylindrical metal powder-sintered porous plate, and the diameters of microchannels on the porous plate are sequentially reduced from inside to outside. A solution containing additives in the storage device is stirred uniformly and then enters into a downhole gas injection base pipe through the gas-liquid mixer to be injected into a stratum, then a carbon dioxide gas compressed by the gas compressor is pumped into the downhole gas injection base pipe through the gas injection pump, and the gas generates microbubbles in situ when passing through the multi-layer porous device under the action of pressure difference.

1. Name of the product in this design: Perforated plate (assembly). 2. Purpose of this design: A general-purpose dynamic joint component for assembling models. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

This invention relates to the field of plant transgenic detection technology, and discloses a method for rapid batch detection of transgenic crops, comprising: Step 1, placing centrifuge tubes containing crop samples to be tested in an array into a multi-well plate to complete batch plate arrangement of samples; Step 2, performing overall mechanized processing based on the multi-well plate, so that the crop samples in the centrifuge tubes are simultaneously ground into powder under mechanical force. This integrated operation process, which places independent centrifuge tubes in an array within a multi-well plate and uses a tissue homogenizer, batch liquid addition equipment, and a centrifuge to simultaneously process all samples, achieves a significant improvement in detection throughput and efficiency. Compared to existing technologies that rely on manual, one-by-one operation, this method overcomes the shortcomings of low detection efficiency and the inability to simultaneously process multiple samples, thus failing to meet the needs of large-scale crop sample screening.

The utility model relates to an adjustable location fixture, including base and install the adjusting mechanism, perforated plate, adjustable location subassembly and adjustable clamping mechanism on the base, perforated plate is installed on the adjusting mechanism, adjustable location subassembly is movably installed on the perforated plate, adjustable clamping mechanism is installed on the adjustable location subassembly, and the adjustable clamping mechanism is installed on the base. The adjustable clamping assembly and the perforated plate are arranged adjacently, a plurality of mounting holes arranged in an array are formed in the perforated plate, the adjustable positioning assembly comprises a positioning rod and a plurality of positioning clamping blocks, and the positioning rod and the positioning clamping blocks can be connected with any mounting hole. The clamping device has the advantages of being capable of meeting the positioning requirements of different workpieces, good in clamping stability and capable of improving production efficiency.

The invention relates to the technical field of experimental equipment, and provides an integrated desalting device and method for high-throughput sample treatment, and the device comprises a base, a movable partition plate and a standard porous plate. The movable partition has first and second working positions. And a wedge-shaped guide positioning mechanism is arranged between the movable partition plate and the perforated plate, and can automatically guide the movable partition plate to lift and transversely align through slope matching when the perforated plate is horizontally pushed in until the movable partition plate is stably supported on the perforated plate and accurate alignment of a sample treatment column and a collection hole is realized, so that rapid and accurate switching between a washing mode and an elution mode is completed. The device is ingenious in structure and easy and smooth to operate.

The utility model relates to the technical field of glue production, and disclose a kind of waste gas purification device for glue production, including purification bucket one and purification bucket two, the inside fixed of purification bucket one is equipped with filter screen, the middle part fixed mounting of pollution valve is positioned at the bottom of purification bucket one, the top of purification bucket one is fixedly equipped with bucket cover one, the inside fixed of bucket cover one is equipped with multi-orifice plate, the surface fixed of bucket cover one is equipped with pulse air pipe, the side fixed of purification bucket one is equipped with conduit;Through filter screen, waste gas can be pretreated, remove the impurities in waste gas, reduce the influence on activated carbon, through breathable support component, activated carbon can be loaded, and breathable capacity can be guaranteed, using the pore structure of activated carbon, waste gas can be adsorbed, by connecting pulse air pipe pulse fan, input pulse wind in bucket cover one, filter screen can be cleaned.

The utility model discloses a waste gas purification device for a chemical production workshop, which relates to the technical field of workshop air purification and comprises a base, a container fixedly mounted at the upper end of the base, an opening arranged at the upper end of the container, a first gas inlet pipe rotatably mounted at the bottom in the container and penetrating through the container, and a perforated plate fixedly mounted at the upper end in the container. According to the waste gas purification device for the chemical production workshop, the driving mechanism drives the movable pieces to rotate around the first gas inlet pipe, the movable pieces stir waste gas, the waste gas is evenly distributed at the lower end of the porous plate, the waste gas is evenly distributed on the porous plate, and therefore the waste gas is purified. The contact area between the waste gas and the porous solid adsorbent is increased, and the contact time is prolonged, so that the reaction efficiency between the waste gas and the purification medium is improved. Meanwhile, waste gas is prevented from forming dead angles in the container, and the residence time and accumulation of the waste gas are reduced.

The utility model relates to the technical field of experimental instruments, and discloses a clinical medical examination oscillation device which comprises an oscillation device body, an oscillation plate is installed in the oscillation device body, the periphery of the top of the oscillation device body is fixedly connected with a sleeve shell, sliding grooves are formed in the two sides of the sleeve shell, and the top of the sleeve shell is fixedly connected with the oscillation plate. A containing plate is slidably connected to the inner wall of the sliding groove, shells are fixedly connected to the two ends of the top of the containing plate, inserting rods are slidably connected to the inner walls of the shells, first springs are fixedly connected to one sides of the inserting rods, the other ends of the first springs are fixedly connected with the shells, and porous plates are fixedly connected to the two sides of the sleeve shell. According to the clinical medical examination oscillation device, the stress amplitude of a test tube in the oscillation process is changed by adjusting the height of the containing plate, the oscillation effect of different frequencies and amplitudes is achieved, and the different requirements of clinical medical examination sample treatment with different oscillation requirements of the same batch are met.

The utility model relates to a ceramic cylindrical membrane sealing structure for beer filtration, which belongs to the technical field of beer filtration and comprises a cylinder body, and a plurality of cylindrical ceramic membranes are arranged in the cylinder body. The utility model has the beneficial effects that the high-temperature-resistant rubber pad is arranged between the upper flange and the barrel flange, so that a first sealing layer can be formed, the high-temperature-resistant rubber pad has the main functions of sealing and protection, and the high-temperature-resistant rubber pad can be kept stable under extreme conditions; the problem that a sealing material is prone to failure under the working conditions of high temperature and high pressure is effectively solved, a sealing ring EDPM in the sealing assembly can be pressed through the effect of a pressing plate, a second sealing layer is formed by combining the sealing performance of the sealing ring EDPM, a sealing matching face used in cooperation with the sealing ring EDPM is machined above a porous plate, a third sealing layer can be formed, and therefore the sealing effect of the sealing assembly is improved. And a multi-layer sealing structure is adopted, so that the leakage risk caused by non-uniform sealing pressure can be avoided.

An apparatus, multi-well plate and method for automated cell lysis and nucleic acid purification and amplification. The plate includes a lysis well, at least one wash well, an elution well, and a PCR chip. The apparatus includes a vertically aligned rotor mixer comprising a magnetic tip and actuators for moving the rotor mixer in a vertical and horizontal directions, to transfer magnetic beads from well to well. The rotor mixer is used to vortex lysis mixtures, wherein the vortexing speed is sufficient to overcome the magnetic attraction between the beads and mixer tip and disperse the beads in solution, to collect nucleic acids such as DNA in an elution solution that is transferred to the PCR chip for amplification of target sequences.

The utility model discloses a perforated plate inoculation instrument. The porous plate inoculation instrument comprises a rotary uniform mixing sample tube mechanism and an alternate uncovering mechanism, wherein the rotary uniform mixing sample tube mechanism comprises a fixed base plate, a support frame, a rotary fixed frame, a rotating wheel, a driving structure and a sample tube frame. According to the perforated plate inoculation instrument provided by the embodiment of the invention, the full-process automatic operation is realized by arranging the rotary uniform mixing sample tube mechanism and the alternate uncovering mechanism, and the rotary uniform mixing sample tube mechanism comprises the fixed base plate, the supporting frame, the rotary fixed frame, the rotating wheel, the driving structure and the sample tube frame; the driving structure can be used for driving the rotating wheel to rotate so that the fixing plate can turn over the sample tube frame, the rotating speed of the sample tube frame is increased, the uniform mixing treatment efficiency of sample tubes arranged on the sample tube frame is improved, the cover opening and liquid pumping speed is increased in cooperation with the alternate cover opening mechanism, and the inoculation efficiency is improved.

A main body part of the gas-liquid parallel flow type internal circulation reaction equipment is of a flat rectangular structure and sequentially comprises a ceramic membrane assembly, a perforated plate gas inlet cavity, a perforated plate with a flange structure, a reactor feed port, a reactor main body part, a reactor discharge port and an overflow structure from bottom to top, the two built-in guide plates divide the loop reactor into an ascending area, a descending area, a bottom gap area and a gas-liquid separation area; a screen is mounted in the middle of the rising area guide plate; according to the reactor, a multi-channel ceramic membrane assembly is arranged in the center of an air inlet plate to generate small-size bubbles, and a porous plate structure is adopted to generate large-size bubbles; the porous plate air inlet holes are distributed on two sides of the ceramic membrane air inlet. According to the invention, millimeter-level bubbles and micron-level bubbles are simultaneously fed, the difference of turbulence degrees at different radial areas is reduced, and the mass transfer efficiency and the adaptive capacity under different working conditions are improved. The energy consumption is reduced, and the manufacturing and production cost is reduced.

The invention discloses a construction method of a model for respiratory tract infection caused by inhalation of pathogenic microorganism aerosol, which comprises the following steps: inoculating respiratory tract cells to an upper chamber of a Transwell cell, culturing until a complete cell barrier is formed, and transferring the cell-loaded cell to an exposure cavity; atomizing the pathogenic microorganism suspension into aerosol, and regulating and controlling environmental parameters of the aerosol in real time; introducing the aerosol into an exposure cavity, and enabling the aerosol to be in direct contact with cells in a manner of simulating the inhalation process of the respiratory tract of a human body; and after the exposure is finished, transferring to a porous plate for continuous culture. The invention further discloses application of the model for respiratory tract infection caused by inhalation of the pathogenic microorganism aerosol. The method has the beneficial effects that the model construction process is simple and convenient, the natural infection process can be highly simulated, the method can be used for simulating a bioaerosol exposure scene after specific treatment, and the method is suitable for pathogen invasion mechanism analysis, host immune response research and efficient screening of anti-infection drugs.

The present invention relates to an electrically conductive pipette mounting adapter, a sample tube opening and closing device, and a sample automatic analysis system, and more particularly to an electrically conductive pipette mounting adapter, a sample tube opening and closing device, and a sample automatic analysis system that integrally perform dispensing of a liquid sample, extraction of nucleic acid, amplification, and detection. A sample tube opening and closing device includes a housing (110) forming an internal space isolated from the outside, including a door portion (120) for transporting a multi-well plate (20) for biological samples having a plurality of sample tubes (10) for containing biological samples into and out of the internal space; and a sample tube opening and closing portion provided in the internal space apart from the multi-well plate (20) for biological samples, automatically opening and closing the sample tubes (10).

Methods of generating organoids on multi-well plates are provided by depositing a polymeric solution comprising cells under conditions which result in a homogenous population of organoids, which can be used for high throughput analysis for drug screening and for determining treatment regimens of a drug.

This invention relates to a multiphysics-coupled optimization design method and equipment for a toroidal pebble bed reactor core used for nuclear thermal propulsion. The method utilizes a stochastic elastic filling algorithm for coated particles to obtain the initial geometric parameter combination of fuel elements; constructs a multiphysics-coupled finite element model, and optimizes the final fuel design parameters under multiple constraints; based on this, Monte Carlo neutronics calculations are used to perform criticality optimization on the core, resulting in a neutronics design scheme that meets criticality and safety requirements; based on this core geometry, computational fluid dynamics analysis is used to optimize coolant distribution by adjusting the porosity of the thermally porous plate, and under conditions that meet temperature and pressure drop limits, the core power and hydrogen mass flow rate range that can achieve preset specific impulse, thrust, and thrust-to-weight ratio performance indicators are determined. Compared with existing technologies, this invention achieves a complete and systematic optimization design for a novel spherical metal-ceramic fuel nuclear thermal propulsion pebble bed reactor core, from concept to meeting preset propulsion performance indicators.

The present disclosure relates to a method for isolating a biological target material from a liquid sample in a multiwell plate using magnetic particles, wherein high efficiency and low elution volumes are achieved by specific movements of the multiwell plate and a magnetic separation plate in relation to each other. Also disclosed is a pre-analytical system suitable for carrying out the method.

The utility model discloses a kind of waste gas collection systems for chemical production, it is related to chemical production waste gas collection technical field, the utility model includes RTO waste gas treatment equipment, and a plurality of production lines one-to-one corresponding dispersion die head and fume hood being set at dispersion die head, it is characterized by: the dispersion die head bottom is fixedly connected with the multiple orifice plate of dense glue hole, the fume hood is set below dispersion die head, the suction port of the fume hood is set along horizontal direction to glue hole, the fume hood is communicated with RTO waste gas treatment equipment by suction pipe;By the setting of structure, waste gas condensate can be prevented from dropping on adhesive tape, and product quality is guaranteed.

This utility model provides a high-efficiency multi-mold press, relating to the technical field of high-efficiency multi-mold presses. It includes: a press body, with an internal extrusion mechanism. A circular mold is located at the bottom of the extrusion mechanism, and a base is fixedly connected to the bottom of one of the circular molds. Hook mechanisms are provided on both sides of the circular mold. The extrusion mechanism includes a pressure plate A, with a pressure plate B at the bottom of pressure plate A, and a strong spring sleeved on the top of pressure plate B. This utility model, by setting a circular mold integrally formed from a perforated plate, allows the material placed inside the circular mold to be pressed and dehydrated. Simultaneously, to facilitate demolding, the taper of the circular mold is set to 1.5°~7°, allowing multiple circular molds to be nested together for efficient material pressing.

The utility model provides a vacuum oven capable of achieving even evaporation. The vacuum oven comprises a bin body, a bin door is rotationally connected to the top of the bin body, a perforated plate is fixedly connected to the top in the bin door, and a vacuumizing opening communicated with the interior of the bin door is formed in the top of the bin door. A heating plate is arranged in the bin body, a partition plate enabling an oil way to flow is arranged in the heating plate, a substrate is placed on the heating plate, an oil inlet / outlet is formed in the bottom or the side portion of the bin body, and the oil inlet / outlet is connected with oil bath heating equipment. According to the utility model, the surface temperature uniformity of the heating plate is ensured by replacing the conventional electric heating with oil bath heating, and meanwhile, the perforated plate is arranged at the lower part of the vacuumizing opening, so that the excessive organic coating on the surface of the substrate is uniformly extracted and volatilized through the perforated plate, and the uniform evaporation and drying of the OLED substrate are ensured.

This invention discloses a method for constructing and sequencing single-cell multi-omics libraries based on a dual-permeable microarray design, comprising the following steps: S1, performing an in-situ nucleic acid molecular labeling reaction on a single-cell or mononuclear suspension of the tissue to be tested in a multi-well plate to tag it with a known base sequence; S2, mixing the reacted single-cell or mononuclear suspension with microbeads carrying the known base sequence and loading it onto a dual-permeable microarray; after the reaction is complete, sealing the chip with sealing oil; S3, performing nucleic acid molecule polymerization and amplification within the chip, and then collecting the liquid within the chip to construct a single-cell sequencing library; S4, sequencing the single-cell library and processing the data to obtain single-cell multi-omics library data. This invention enables high-throughput analysis of multi-omics genetic information, including transcriptomics and chromatin availability, at the single-cell level at a low cost and with rapid convenience.

The utility model discloses an emulsion emulsification device relates to emulsion processing technical field, the utility model discloses a middle jar body is provided with the stirring motor on the jar body top, and the axle of stirring motor is connected with the main shaft in the jar body, and the upper portion of jar body is provided with the feed pipe, and the lower portion is provided with the discharge pipe, the lower portion of jar body is provided with the multi -hole plate, and the surrounding edge of multi -hole plate is fixedly provided with a group of separating piece, the gap is provided with between each separating piece, and the edge of separating piece and jar body inner wall leave the gap. The utility model discloses the multi -hole plate of setting up installing separating piece can rotate with the main shaft, and in the emulsification process of stirring, can be through centrifugal force and make emulsion raw materials throw out and scatter through the gap between each separating piece, make emulsion raw materials diffuse after impacting jar body inner wall, and the movement of combining multi -hole plate forms complex turbulence, and the raw materials of water phase and oil phase can be quick dispersion emulsification.

The present technology relates to a semiconductor device and a multi-well plate that can reduce the number of connection terminals. A semiconductor device comprises an electrode array portion composed of a plurality of electrodes, an MEA that outputs one or more first digital data obtained by measurement using the electrode array portion, and a first multiplex portion that multiplexes N first digital data output from the plurality of MEAs and outputs M second digital data that is less than N. The present technology can be applied to a multiwell plate.

The utility model discloses a confocal perforated plate for tube formation experiment, which comprises a base plate structure, accommodating hole structures and bulge structures, the accommodating hole structures are equidistantly arranged on the upper surface of the base plate structure, and the bulge structures are arranged at the bottoms of the inner walls of the accommodating hole structures. According to the confocal perforated plate for the tube forming experiment, self-leveling of matrigel is achieved through combination of micron-sized annular protrusion arrays designed at the bottoms of the holes and super-hydrophilic surface modification, the standard deviation of the thickness of a gel layer is controlled within + / -3 microns, and the height difference of the liquid level is reduced to lt through side wall gradient hydrophobic treatment (top hydrophobic / bottom hydrophilic); 0.1 mm, and halo artifacts in confocal imaging are eliminated.

Method for manufacturing a multicellular panel by conductive or radial welding. The invention relates to a method for manufacturing a multicellular panel (500) comprising a honeycomb structure (300) and a first skin (100) made of a thermoplastic composite material, the honeycomb structure (300) having a plurality of walls (330) extending along a first direction (X) between a first face (310) and a second face (320) of the honeycomb structure (300), the method comprising welding the first skin (100) to the first face (310) of the honeycomb structure (300), the welding comprising a step of heating the first skin via a radiative source (600) or a resistive source (700), followed by a step of bringing the heated first skin (100) into contact with the first face (310) of the honeycomb structure (300), and then a step pressing of the alveolar structure (300) against the first skin (100).Figure for the abridged version: Fig.2.

An apparatus, system, and method for studying protein folding in the native cellular environment is provided. The invention, termed pcIC-FPOP, combines pulse-chase experiments with in-cell protein footprinting coupled to mass spectrometry. This enables very high resolution information on the folding or mis-folding of proteins. The system (100) includes a multi-well plate (110), an incubator (120), a stage (130), a subsystem of reservoirs (172) and pumps (174), a laser source (140) and beam steering optics (150), and a computer system (160) programmed with a control module (162) to control the operation of the laser (140), optics (150), incubator (120), stage (130), or pumps (174), or some combination. This method permits studies that fill gaps in knowledge on protein folding and its role in disease.

The utility model discloses a kind of vacuum vertical reduction tank structure, including reduction tank body, the inner peripheral wall of reduction tank body is equipped with several spaced-apart perforated plate, multiple vapor channels are formed between each perforated plate and the inner wall of reduction tank body.The reduction tank structure provided by the utility model is placed into reduction furnace when using, and heating is implemented to charge ball in the body of reduction tank by using reduction furnace, since multiple vapor channels are formed between perforated plate and the inner peripheral wall of reduction tank body, metal ball can directly escape from perforated plate to vapor channel after being heated to reach reaction temperature and produce metal vapor, and directly reach condensing zone from vapor channel for condensation;The possibility of recondensation caused by high-temperature metal vapor passing through ball layer with lower temperature is avoided, so that reduction furnace can speed up reduction speed and efficiency, and energy loss is reduced.

A kind of microfluidic unit, multi-well plate and PCR instrument facilitating reagent addition, it relates to enzymology or microbiology device technical field, the technical scheme adopted includes reaction tube, reaction tube bottom end is closed and top end is provided with opening, at least one reagent container for heating and melting and releasing the reagent contained in inner wall of reaction tube is arranged;Reagent container and reaction tube bottom end form reaction chamber, reagent container is also provided with the passage that is communicated with opening by reaction chamber;Reagent container is internally provided with the reagent cavity for preloading reagent;Protective cover is arranged in the top of reaction tube, the central part of protective cover is provided with probe hole, probe hole corresponds with passage.This utility model melts reagent container that is preloaded with reagent and can be built into reaction tube, user only needs to add tissue sample, accurately controls the temperature of reaction tube to let specified reagent container melt and release the reagent required with sample mixing to complete reaction, can realize microfluidic, on-demand mixing reagent.