54 results about "Tissue expansion" patented technology

Expandable devices and methods for treating and enlarging a tissue, an organ or a cavity. The device is composed of a hollow expanding pouch made of a resorbable material or a perforated material that can be attached to a filling element. The pouch can be filled with a biocompatible materials, one or more times in few days interval, after the insertion of the device. While filling the pouch every few days the tissue expands and the filling material if it is bioactive start to function. The devices allow immediate direct contact between the filling material and the tissue. These devices and methods can be used for example for: horizontal and vertical bone augmentation in the jaws, soft tissue augmentation, fixating bone fractures etc.

Bioresorbable inflatable devices and tunnel incision tool and methods for treating and enlarging a tissue or an organ or a tube or a vessel or a cavity. The device is composed of a hollow expanding pouch made of a resorbable material that can be attached to a filling element. The pouch can be filled with a biocompatible materials, one or more times in few days interval, after the insertion of the device. While filling the pouch every few days the tissue expands and the filling material if it is bioactive start to function. The tunnel incision tool composed of a little blade that emerges from the surface of the tool in order to make shallow incisions in the surrounding tissue therefore enabling easy expansion of the tissue. This device and method can be used for example for: horizontal and vertical bone augmentation in the jaws and the tunnel incision tool is used to make shallow incisions in the periosteum when using the tunnel technique, sinus augmentation when the device is placed beneath the Schneiderian tissue, vessels widening if the pouch become a stent etc.

Apparatus and method for harvesting selected vessels in the body of a patient include manual manipulation of a rigid dissecting endoscope and the reconfiguration thereof to facilitate tissue dissection and tissue dilation in the formation of an anatomical space about the vessel within which side-branch vessels may be manipulated in preparation for severance and removal of the vessel from the anatomical space.

An injectable composition having dermal filling and tissue expanding activity comprises (1) a quantity of elastin sufficient to bring about dermal filling and tissue expansion when injected into a subject in need of dermal filling and tissue expansion, and (2) a pharmaceutically acceptable carrier. The composition can further comprise collagen, in other alternatives, the composition can further comprise hyaluronic acid, and one or more of the elastin, the collagen, and the hyaluronic acid, if present can be cross-linked, either intramolecularly or intermolecularly. The elastin, however, is the primary filler, even if collagen or hyaluronic acid are included in the composition

Exemplary embodiments of the present disclosure provide method and apparatus for facilitating stretching of a bio-logical tissue by forming a plurality of micro-slits in the tissue. Each micro-slit can be less than about 2 mm or less than about 1.5 mm long, or even less than about 1 mm, such that small gaps that can heal quickly can be formed when the tissue is stretched. The micro-slits can be formed using a plurality of cutting arrangements or an ablative laser. The micro-slits can be formed in various patterns, including staggered rows, circular or spiral patterns, or random patterns.

Apparatus and method for harvesting selected vessels in the body of a patient include manual manipulation of a rigid dissecting endoscope and the reconfiguration thereof to facilitate tissue dissection and tissue dilation in the formation of an anatomical space about the vessel within which side-branch vessels may be manipulated in preparation for severance and removal of the vessel from the anatomical space.

The invention provides systems and methods for tissue expansion. A tissue expander may have an implant portion which may be used to expand the tissue. A delivery/drainage system may be also be provided, which may be in fluid communication with a pocket surrounding the tissue expander. Various port configurations may be provided that may provide access to the implant portion and/or the delivery/drainage system. The tissue expander may advantageously help prevent or treat infection, or check the state of the pocket surrounding the tissue expander.

A device which allows the insertion of a flowable filling material through at least part of a dental implant inside the body to touch the bone. The implant can be hollow and to have a side perforation connecting the space inside the implant with the surrounding of the implant. This perforation can be placed initially outside the alveolar ridge. The device can allow immediate direct contact between the filling material and the tissue and for the displacement of the soft tissues covering the bone.

Expandable absorbable implants have been developed that are suitable for breast reconstruction following mastectomy. The implants can be implanted in the vicinity of a tissue expander, for example, by suturing to the detached edge of the pectoralis major muscle to function as a pectoralis extender, and used to form a sling for a tissue expander. The implants, which permit tissue-ingrowth and slowly degrade, can be expanded in the breast using a tissue expander in order to form a pocket for a permanent breast implant. After expansion, the tissue expander can be removed and replaced with a permanent breast implant. The expandable implants help reduce patient discomfort resulting from tissue expansion, and avoid the need to use allografts or xenografts to create the pocket for the tissue expander. The expandable absorbable implant preferably comprises poly-4-hydroxybutyrate or copolymer thereof.

An improved injector needle apparatus is described with inherent properties for increasing linear flow rates when inserted into a subcutaneous port during tissue expansion thus decreasing procedure time.

The invention relates to nanocomposites comprising of (i) hydrogels synthetized by copolymerization of N-isopropylacrylamide and/or acrylamide and/or acrylic acid monomers and of (ii) layer silicates, and to the process for preparing them. The invention covers osmotically active hydrogel expanders containing said nano-composites, suitable for tissue expansion and the use of said materials for obtaining live skin.

A device for maintaining or achieving soft tissue expansion applicable to any body region already temporarily expanded including: an adhesive element deformable and capable of adapting to the shape of this body region, and which can then itself become mechanically rigid enough to resist tendency of the expanded tissue to recoil or to which a second material can be applied to form a stent adapted to the shape of the body area to provide the necessary structural rigidity to prevent recoil of the expansion and thereby induce its retention of its expanded shape after the stent is removed.

An ultrasound diagnosis apparatus includes an ultrasound probe 1, in which a plurality of transducer elements are arrayed and which converges and radiates an ultrasound on a patient and detects a reflection wave thereof, and images a tomogram of the patient, using the reflection wave, wherein an expansion detector 22 operates a difference between a radial component of a therapeutic converging beam of a movement amount of each part, and an integral amount integrated from the radial component, and extracts a tissue expansion generated at a part of the patient from the tomogram, and wherein the movement amount is calculated by performing a pattern matching between tomograms imaged with different frames.

Non-fluidized tissue expanders, tissue expander systems, and methods of expanding tissue are disclosed. The tissue expanders, systems, methods of the present invention incorporate an expandable encapsulated body mass implantable within the patient and operative to selectively expand to promote growth of an enlarged area of skin and subcutaneous tissue. Such tissue expansion is accomplished utilizing internal one or more distraction mechanisms disposed within the tissue expanders that are operative to expand by mechanical or electro-mechanical means. The present invention omits any type of inflatable body requiring the injection of fluids to effectuate expansion of the tissue expander.

The invention discloses a transparentizing reagent and application thereof in biological tissue material optical imaging as well as a living body skin tissue transparentizing imaging method. The transparentizing reagent is mannose or a mixture formed by dissoving mannose and 1,3-dimethyl-2-imidazolinone in a solvent. The transparentizing reagent can be applied to the biological tissue material optical imaging. The living body skin tissue transparentizing imaging method comprises the following steps: removing hairs on the surface, cleaning and drying; fixing and placing a skin tissue on a focalplane of an optical imaging system; dropwise adding the transparentizing reagent to the skin tissue at an imaging position, and standing for 5-30 minutes; imaging; and after the imaging is finished,wiping the transparentizing reagent, and repeatedly scrubbing and cleaning the surface of the skin tissue with normal saline or phosphate buffer solution, so that the skin tissue restores the originalstate. The reagent disclosed by the invention can not produce obvious tissue expansion or tissue shrinkage when in use, a detailed structure of a biological material can be completely stored, transparentizing time is short, transparentizing capability is high, and the reagent can be applied to the biological tissue material optical imaging.

The invention provides a rapid tissue transparent processing method based on water-soluble reagent and an application thereof. The processing method comprises the following steps: placing a tissue fixed through paraformaldehyde into a tissue expansion treating agent, sufficiently soaking to loosen and expand the tissue, and removing lipid; placing the tissue sufficiently soaked by the tissue expansion treating agent into a tissue contraction agent so that the tissue can be contracted to an original state from the expansion state, and acquiring an initial transparent effect; placing the tissuesufficiently treated in the tissue contraction agent into a refractive index matching reagent to soak, and finally obtaining the highly transparent tissue with relatively uniform refractive index. Thetissue treated through the method disclosed by the invention is highly transparent, and can be used for tissue entire three-dimensional fluorescence imaging, thereby realizing three-dimensional high-resolution imagining on the whole brain neural network and an organ vascular network structure.

A device for maintaining or achieving soft tissue expansion applicable to any body region already temporarily expanded including: an adhesive element deformable and capable of adapting to the shape of this body region, and which can then itself become mechanically rigid enough to resist tendency of the expanded tissue to recoil or to which a second material can be applied to form a stent adapted to the shape of the body area to provide the necessary structural rigidity to prevent recoil of the expansion and thereby induce its retention of its expanded shape after the stent is removed.

The present invention relates to a device for treating male genital hypoplasia, growing its tissue and correcting existing curvature. The device of the present invention is unique in that it employs an external genital fixation system (1; 13) to which a diameter device (5) and a gland protection system (15) are connected. The external genital fixation system (1) and the upper element (13) create a traction force on the male external genitalia. The diameter device (5) creates a tissue expansion on the male genitalia. The gland protection system (15) avoids possible wounds, which makes it possible to use it for a long time without discomfort. Users of the device can wear it for months, several hours a day. Thus, for the treatment of male genital hypoplasia, timely tissue expansion and the opportunity to prolong the expansion are fundamental.

The present invention is directed to compositions and methods for delivering a tissue scaffold comprising a perfluorocarbon emulsion to an individual in need of tissue expansion.