18results about "Vivisection diagnostics" patented technology

This invention discloses a one-button temperature-controlled visual thermal surgical scalpel, relating to the field of medical device technology. It includes a scalpel body with an insulating pad on its outer wall. A temperature adjustment button and a one-button temperature control button are installed at one end of the outer wall of the scalpel body near the insulating pad. An electrothermal transducer is located inside the scalpel body, converting electrical energy supplied by a power source into heat energy via leads and a plug. An electrothermal blade head is located at one end of the inner wall of the scalpel body near the electrothermal transducer. This invention uses a rotating block, transmission ring, and rotating cylinder to extend and retract the electrothermal blade head. When other instruments need to be replaced during surgery or after the surgery, the scalpel body shell provides comprehensive physical isolation from the residual heat of the electrothermal blade head, effectively preventing medical personnel from accidentally touching the hot blade head. This reduces the risk of burns caused by the high-temperature blade head and improves the operational safety and ease of use of the thermal surgical scalpel.

The present application relates to the technical field of forensic autopsy instruments, in particular to a non-vibration laser craniotomy system and method for forensic autopsy, which is equipped with a high-precision laser cutting end through a composite laser cutting unit, realizes non-contact bone tissue resection, completely eliminates the secondary damage of mechanical vibration to brain tissue, and guarantees the original pathological morphology of the sample; cooperates with the negative pressure unit to fix the skull and simultaneously removes bone chips, smoke, biological aerosol and other cutting chips, avoids the damage of brain tissue caused by the attachment of cutting chips on the surface of the covering brain tissue; utilizes the cooling unit to cool the cutting starting point, avoids the thermal effect denaturation caused by the local temperature rise in the laser cutting process, and guarantees the accuracy and reliability of the cutting; at the same time, the central controller plans the cutting path and parameters according to the skull information, ensures the precise fitting of the cutting process to the complex curved surface of the skull, and significantly improves the automation degree and repeatability of the craniotomy operation.

In one aspect, the invention relates to an automated method of transferring biological material (117) from a sample disposed on a planar substrate (115) into a collection tube, using a dissection tool (120) that has an internal passageway (121) extending between first and second ends of the tool and an air-permeable filter element (125) that spans the internal passageway. The tool first end is provided with an orifice (123) and a scraping blade (124). The method comprising steps of: a) physically detaching the biological material from the planar substrate (115) using the scraping blade (124) of the dissection tool; b) during step a), generating an underpressure at the tool second end by connecting the internal passageway (121) to a vacuum generator (150), to create an uplifting airstream at the tool orifice (123), which suctions detached material into the internal passageway (121), where it is held at an underside of the filter element (125); c) attaching the collection tube to an outer surface of the dissection tool in an airtight manner; and d) generating an overpressure at the tool second end, by connecting the internal passageway to a pressure reservoir (160), thereby creating a pressure pulse that ejects the biological material held at the underside of the filter element, transferring the material (117) into the collection tube.

A surgical tool apparatus is provided. The apparatus may a handle, a shaft extending distally from the handle, a receiver defined in a proximal end of the handle opposite the shaft, a hub disposed in the receiver, and a foot disposed on a distal end of the shaft opposite the handle. The foot may include an opening. The apparatus may further include a channel defined from the receiver to the opening, and a cutting instrument disposed in the channel. The cutting instrument may be fixed to the hub, and include a tip that is configured to dissect tissue during a surgical procedure. Some or all of the apparatus may be made of a disposable material, such as plastic or a polymer material.

The present invention provides a rapid method for forensic drug testing in a post-mortem individual using muscle tissue and fluid associated with the muscle tissue obtained from remains of the post-mortem individual. The method comprises obtaining muscle tissue and associated fluid from a post-mortem individual, collecting the fluid associated with the muscle tissue, analyzing the fluid associated with the muscle tissue to detect and quantify one or more non-naturally occurring drugs in the post-mortem individual, and identifying the one or more non-naturally occurring drugs in the post-mortem individual. The detection and quantification of non-naturally occurring drugs in muscle tissue and associated fluid is surprisingly faster than detection and quantification of the non-naturally occurring drugs in muscle tissue obtained from the same post-mortem individual and prepared as muscle tissue homogenates using the LC-MS / MS method, with results obtained in as soon as three hours.

The present application relates to the technical field of ultrasonic knife equipment, and discloses a multifunctional ultrasonic dissecting knife, which comprises a piezoelectric transducer, a variable amplitude rod, a frequency generating module, a working head, a detection part and a control part, and further comprises: the detection part is configured to obtain tissue information of a region to be dissected, wherein the tissue information comprises tissue load information and tissue impedance information; the control part is electrically connected with the detection part, the variable amplitude rod, the frequency generating module and the piezoelectric transducer respectively, and is configured to determine a preset output amplitude of the variable amplitude rod according to the tissue information, and determine an electric signal frequency of the frequency generating module according to the output amplitude. By acquiring the tissue load and impedance information in real time, the output amplitude of the variable amplitude rod and the electric signal frequency of the frequency generating module are intelligently adjusted, the dynamic adaptability and precise control of the energy output of the ultrasonic dissecting knife are realized, and the operation efficiency and safety are improved.

In one aspect, the present invention relates to an automated method for transferring biological material (117) from a sample disposed on a planar substrate (115) into a collection tube using a cutting tool (120) having an internal passageway (121) extending between a first and second end of the tool and a breathable filter element (125) spanning the internal passageway, the first end of the tool being provided with an orifice (123) and a scraping blade (124). The method comprises the steps of: a) physically separating biological material from a flat substrate (115) using a scraping blade (124) of a cutting tool; b) during step a), creating a negative pressure at a second end of the tool by connecting the internal passage (121) to a vacuum generator (150) to create an upward air current at the tool orifice (123), which draws the separated material into the internal passage (121), where it is retained under a filter element (125); c) airtightly attaching a collection tube to the exterior of the cutting tool; and d) creating an overpressure at the second end of the tool by connecting the internal passage to a pressure reservoir (160), thereby creating a pressure pulse that expels the biological material retained under the filter element and transports the material (117) into the collection tube.

The application discloses an experimental animal spinal column specimen dissection instrument and a dissection method. The dissection instrument comprises a fixing device, a scanning device, a cutting device and a control device. The fixing device is used for fixing the experimental animal spinal column specimen. The scanning device is used for scanning the fixed experimental animal spinal column specimen and transmitting a scanning image to the control device. The cutting device cuts the experimental animal spinal column specimen according to a cutting instruction of the control device or manually. The dissection instrument of the application integrates the fixing and cutting functions, significantly improves the efficiency and precision of the experimental animal spinal column specimen dissection, reduces the error and labor intensity of manual operation, makes the dissection process more consistent and reliable, and has high flexibility and adaptability, so that the dissection instrument can meet the dissection requirements of spinal column specimens with different sizes and curved shapes, and provide more reliable dissection samples and experimental data support for the fields of spinal column disease research, spinal cord injury repair and artificial vertebral body / intervertebral disc implant research and development.

The invention discloses a skull dissection support convenient to adjust, and relates to the technical field of skull dissection supports, the skull dissection support comprises a bottom frame and a placing frame, and a local adjusting assembly is arranged at the top of the bottom frame. According to the skull dissection support convenient to adjust, in the skull dissection process, when a certain position of the skull needs to be lifted, an operator holds the containing frame with one hand, the other hand pushes a connecting ring rod on the lower portion, the second hydraulic cylinder is moved to the position below the position needing to be adjusted, and then the second hydraulic cylinder is moved to the position below the position needing to be adjusted; then a first hydraulic cylinder is adjusted to drive extrusion teeth on an extrusion plate to make contact with the outer side of an annular adjusting rail, two triangular sliding blocks are limited, then the hydraulic cylinder is adjusted to drive a connecting block to ascend and descend, in the ascending and descending process of the connecting block, ascending and descending of the local position of the containing frame are achieved, and the containing table at the deflection rod corresponding to the connecting block ascends and descends; adjustment of the needed position in the skull dissection process is achieved through the local adjusting assembly, and the effect that the skull does not need to be disassembled and assembled repeatedly is achieved.

The invention discloses an auxiliary device for medicine injection in the field of medicine injection auxiliary instruments, the auxiliary device comprises a fixing assembly and a guide assembly, the fixing assembly comprises two connecting plates and a fixing plate fixed between the connecting plates; the guide assembly comprises a guide plate and a guide cylinder, rotating rods are arranged on the two sides of one end of the guide plate, and the two rotating rods are rotationally connected to the opposite faces of the two connecting plates correspondingly; the other end of the guide plate is fixedly connected with a fixing rod, the other end of the fixing rod is fixedly connected with the guide cylinder, the upper surface of the guide plate is provided with a guide groove for a syringe needle to pass through, the guide groove and the axis of the guide cylinder are located on the same straight line, and the upper surface of the guide plate is slidably connected with a connecting block in the length direction of the guide plate. A screw is in threaded connection with the fixing plate and penetrates through the fixing plate to be rotationally connected with the connecting block, and inclination angle scales are arranged at the end, close to the guide cylinder, of the connecting plate. By means of the auxiliary device, medicine can be injected into the skin of the foot or the hand of a dead individual more accurately.

The utility model relates to the technical field of dissection tools, and more particularly to an animal dissection tool, which comprises: a holding portion configured as a columnar structure that can be held by a user and extends in a first direction; a first blade portion structure connected to the holding portion, wherein the first blade portion structure is provided with a first blade surface with double inclined surfaces in a direction away from the holding portion; and a second blade portion structure connected to the holding portion, wherein the second blade portion structure is provided with a second blade surface with a double curved surface in a direction away from the holding portion. The dissection tool provided in the application is provided with the first blade portion structure and the second blade portion structure, the first blade portion structure and the holding portion form a mechanical transmission system based on the lever reinforcement principle, and an operator can accurately guide the cutting force to the working surface of the blade portion through a wrist rotation action. The curved surface design of the second blade portion structure can be attached to the skull, which is beneficial to the separation of muscles / fascia and the skull.

The application relates to the technical field of anatomical medical instruments, in particular to a fixing and opening device for taking out a brain, which comprises a connecting mechanism, the upper portion of the connecting mechanism is provided with a fixing mechanism, the upper portion of the fixing mechanism is provided with a sectioning mechanism, the sectioning mechanism comprises a manipulating assembly and a sectioning assembly, a third connecting hole is arranged in the top center of the fixing piece, a fixing cover is arranged on the outer side of the fixing piece, a limiting hole is arranged in the middle portion of the fixing cover, and the size of the limiting hole is matched with the outer side of the fixing piece. The first fixing groove is arranged to ensure the stable placement of the bottom of the skull, the first motor drives the electric saw blade to make 360-degree annular sectioning, the electric telescopic rod drives the sectioning depth of the electric saw blade to be controlled, the problems that the steel saw blade is broken due to the rolling of the human head caused by the unstable fixation or the surface structure of the brain is damaged due to the overdeep sawing so that the taken-out brain cannot be used are avoided.

The invention discloses a dead fetus brain tissue pathological dissection device which comprises a rectangular barrel and a fixing assembly, a containing cavity used for containing stationary liquid is formed in the rectangular barrel, a transparent glass cover is arranged at the upper end of the rectangular barrel in a turnover opening mode, the fixing assembly comprises a fixing ring and an arc-shaped pressing block, the fixing ring is arranged in the containing cavity, and the arc-shaped pressing block is arranged in the containing cavity. One end of the arc-shaped pressing block is connected with the rectangular barrel, the arc-shaped pressing block is arranged in the fixing ring in a sliding mode, a threaded rod is arranged at the outwards-protruding end of the arc-shaped pressing block, one end of the threaded rod is rotatably connected with the arc-shaped pressing block, and the other end of the threaded rod penetrates through the fixing ring, extends out of the fixing ring and is in threaded connection with the fixing ring; the fixing assembly is arranged in the rectangular barrel containing the stationary liquid, the dead fetus is directly dissected in the stationary liquid, the brain tissue is in contact with the stationary liquid after being exposed, the brain tissue does not need to be additionally transferred into a fixing container from a dissecting table, and therefore the risk that the brain tissue is damaged in the transferring process is avoided.

Primary repeating patterns in recorded spatiotemporal data are identified, extracted, and / or refined by converting the data into phase data, determining a global cycle length with discrete time points per cycle, determining onset times in the original recording, calculating the best global phase progression over 2π, and over the entire cycle length, using the time points and onset times, assigning a singular value to each spatial location and generating a visual display of the pattern. Variations of the method may be used to identify features of the pattern such as spatial movement, focal sites, drift, and stability.

The utility model discloses an integrated insect dissecting device which comprises a box body 1, the upper surface of the box body 1 is provided with an amplifying mechanism 2, a fixing mechanism 3 and an unplaning disc 4, the amplifying mechanism 2 comprises a gooseneck 201 and a magnifying glass entity 204 which are fixedly installed on the upper surface of the box body 1, and the fixing mechanism 3 comprises a rectangular sleeve 303, a strip-shaped sliding plate 304, a lead screw 306, a connecting rod 308 and a rubber tip 309. By arranging the movable magnifying lens entity and the effective fixing mechanism, the working efficiency of large insect dissection observation is remarkably improved, the magnifying lens entity can be bent at any angle through the gooseneck pipe and the first resistance sleeve, an observer can conveniently, comprehensively and clearly observe all parts of an insect, the position and focal length of the microscope do not need to be frequently adjusted, and the working efficiency is improved. Meanwhile, the fixing mechanism can stably fix the insects of different sizes, the insects are prevented from moving in the dissecting process, and therefore the accuracy and smooth proceeding of dissecting operation are guaranteed.

The present application provides a fast-connected laboratory animal test bench, which belongs to the technical field of experimental supplies, and comprises a test bench, a liquid storage tank and a plurality of fixing bolts, and the fixing bolts are all arranged on the test bench, and is able to bind ropes to fix animals, wherein, the test bench is provided with a liquid discharge groove located inside a range surrounded by all the fixing bolts, and the liquid storage tank is arranged at a bottom of the test bench and is configured to accommodate the waste liquid discharged from the liquid discharge groove. The overall structure of the present application is relatively simple. The animals to be tested are tied up with ropes, and the ropes are bound to the fixing bolts. The bound animals are located above the liquid discharge groove on the upper part of the test bench.

There is provided an apparatus for positioning or navigating at least two needles (2) relative to an object, comprising at least two holding devices (3) for movably holding the needles (2), wherein the holding devices (3) each comprise an adjusting device (4) for moving the needles (2) independently of each other and relative to the object. Further, a system comprising such an apparatus and an imaging device (7) for monitoring and / or guiding a position of at least one needle (2) in the object and a method for induction of a heart failure in an animal with the use of such an apparatus or with the use of such a system are provided.

There is provided an apparatus for positioning or navigating at least two needles (2) relative to an object, comprising at least two holding devices (3) for movably holding the needles (2), wherein the holding devices (3) each comprise an adjusting device (4) for moving the needles (2) independently of each other and relative to the object. Further, a system comprising such an apparatus and an imaging device (7) for monitoring and / or guiding a position of at least one needle (2) in the object and a method for induction of a heart failure in an animal with the use of such an apparatus or with the use of such a system are provided.