The invention discloses a preparation syringe integrated structure. The preparation syringe integrated structure comprises a stretchable piston, a needle cylinder, a syringe needle, an exposed rubberplug, a sealing fin, a built-in rubber plug, a sealing rubber plug and a cohesion rubber plug, a stretchable piston is arranged at one end of the needle cylinder, and a clamping column is arranged atthe other end of the needle cylinder, the exposed rubber plug is mounted on one side of stretchable piston, away from the needle cylinder, the built-in rubber plug is mounted in the needle cylinder, scale lines are formed on the circumference surface of the needle cylinder. According to the preparation syringe integrated structure, a storage medicine bottle and a syringe are designed as an integrated structure, intermediate links are reduced, and thus the waste of the liquid medicine caused by incomplete liquid medicine suction and liquid medicine overflowing is reduced, at the same time, professional risks of medical workers are reduced, and the problem that particle formed due to repeated puncture causes the potential injure to a patient is reduced; the matched stretchable piston structure reduces the overall length, and provides convenience for the operation of puncturing; and by the syringe needle, of which the section is of an epsilon-shaped structure, the waste of the liquid medicine is effectively avoided as well.