The invention provides a tailing cementing agent which is formed by mixing a raw material dry basis and water. The tailing cementing agent is characterized in that the dry basis is prepared from, by weight, 5%-12% of slag, 1%-5% of fly ash, 4%-6% of furnace slag, 3%-6% of lime sludge, 5%-20% of cement clinker, 2%-10% of industrial by-product gypsum and 75%-90% of tailing sand; the weight percentage of the raw material dry basis ranges from 65% to 75%, and the weight percentage of the water ranges from 25% to 35%. The tailing cementing agent is high in strength, simple in process, large in fluidity and suitable for gravity-flowed filling; less cement or cement clinker exists in the component of filling slurry, the utilization rate of the tailing sand is high, and the production cost is very low; the tailing sand is not subjected to stage treatment, the tailing cementing agent is not limited to single tailing, the application range is wide, stacking and pollution problems of the tailings are partially solved, resource utilization of other industrial waste residues such as steel slag, the slag and the industrial by-product gypsum is achieved, and the environmental protection effect is very significant.