The invention discloses a multi-parameter intelligent control system for controlling the boiler main steam temperature. The multi-parameter intelligent control system for controlling the boiler main steam temperature comprises a water supply system and a main steam system. The main steam system is provided with a boiler steam pocket, a first level superheater, a first level desuperheater, a platen superheater, a second level desuperheater, a second level superheater and a steam collecting header, wherein the first level superheater, the first level desuperheater, the platen superheater, the second level desuperheater, the second level superheater and the steam collecting header are sequentially arranged on a steam output gas channel of the boiler steam pocket. Through mutual effect and cooperation of an internal model controller, a temperature reduction control system, a third disturbance module, an internal model module and a self-adapting PID correction module, control over the main steam temperature is achieved, the main steam temperature is stabilized, and cumulative deviation of the main steam temperature is reduced. The multi-parameter intelligent control system for controlling the boiler main steam temperature has the beneficial effects that the main steam temperature is stable, response to disturbance signals is rapid, the influence on main steam by disturbance is reduced, and the cumulative deviation of the main steam is small.