33 results about "Benzopyrrole" patented technology

The invention relates to the field of drug synthesis, and in particular relates to a preparation method of an antidepressant drug-vilazodone. The preparation method is characterized by comprising the following steps of: protecting a 1-location nitrogen atom of 5-cyano benzopyrrole used as an initial raw material through utilizing toluenesulfonyl, carrying out 3-location Friedel-Carfts acylation, and selectively reducing carbonyl into methylidyne so as to obtain 1-tosyl-3-(4-chlorobutyl)-5-cyano benzopyrrole; reacting the 1-tosyl-3-(4-chlorobutyl)-5-cyano benzopyrrole with 5-(piperazine-1-radical) benzofuran-2-nonanoic acid-ethyl ester hydrochloride, hydrolyzing through one step, and removing tosyl and ethyl at the same time so as to obtain 5-(4-(4-(5-cyan-1H-benzopyrrole-3-radical) butyl) piperazine-1-radical) benzofuran-2-carboxylic acid; finally, amidating so as to obtain vilazodone, and salifying vilazodone with hydrogen chloride so as to obtain hydrochloric acid vilazodone. The method can be used for overcoming a plurality of defects of a conventional synthetic method, and has the advantages of easiness in raw material acquisition, high yield, good selectivity, convenience in operation, suitability for industrial production and high application value.

The invention relates to a cyclobutadiene benzopyrrole derivative with an AEE effect and preparation thereof and belongs to the technical field of organic synthesis. The cyclobutadiene benzopyrrole derivative is a benzo condensed ring derivative with pyrrole-cyclobutadiene-benzene ring combined in a large pi conjugated structure, and has an AEE property; the light-emitting wavelengths are higher than 550nm, the light is located in an orange light region or a red light region, and the derivative can be used for synthesizing an infrared or far infrared organic fluorescent dye. The method of preparing the cyclobutadiene benzopyrrole derivative is a one-pot method which mainly comprises the steps of performing continuous Sonogashira reaction and cyclotrimerization reaction on a pyrrole derivative iodated in sites 3 and 4 to form an aromatic pi system with a five membered ring combined with a four membered ring and a six membered ring. The method is simple to operate and the used raw materials are cheap and easily available.

The invention relates to the field of display and especially relates to compound, an organic light-emitting device and a display device. The compound is shown as a formula I in the following image description, wherein X group is chosen from carbazolyl, dihydroacridine, dihydrophenazine, phenoxazine, phenothiazine, benzopyrrolocarbazolyl, benzofurocarbazolyl, benzothienocarbazolyl, indenocarbazolylor triphenylamine; the X perssadgroup is substituted or unsubstituted; A group is chosen from acryl with a carbon atom number as 6 to 30, alkyl with a carbon atom number as 1 to 20 or cycloalkyl witha carbon atom number as 3 to 20; the A group is substituted or unsubstituted.

The invention relates to a synthesis method of boron aza-naphthalene thiophthene hetero arene and a derivative thereof. The photophysical properties and single crystal diffraction structures of the compounds are tested, and the potential application value of the organic material in organic electrochemistry is further researched. According to the structural formula of the compound, R1, R2, R3 and R4 are independent substituted or non-substituted groups which comprise alkyl and aryl (benzene ring, thiophene ring, furan ring, pyrrole, pyridine, benzothiophene, benzofuran, benzopyrrole, quinoline,naphthalene ring, anthracene ring, phenalene, naphthacene, pyrene, a compound shown in the description, linear or angled pentacene, hexacene, indene, fluorene and the like). R3 and R4 can also be used as a single substituted halogen atom X : F, Cl, Br and I. The formula is shown in the description.

The invention relates to a synthetic method of bis-pyrrole fused boron naphthazine and derivatives of bis-pyrrole fused boron naphthazine. The photoelectric physical properties of the compounds are tested and studied, and study on application value of the organic materials in preparation of OLED devices is carried out. The structure formula of the compounds is disclosed in the invention, wherein R1, R2, R4, and R5 are respectively used for representing independent substituent groups or non-substituent groups including alkyl, aryl (phenyl ring, thiophene ring, furan ring, pyrrole, pyridine, benzothiophene, benzofuran, benzopyrrole, quinoline, naphthalene ring, anthracene nucleus, phenalene, tetracene, pyrene, linear or angled pentacene, hexacene, indene, fluorine, and the like), and R3 is used for representing alkyl, acyl, nitro, sulfonic group, aldehyde group, diazo group, or single substitution halogen atom X, F, Cl, Br, and I.

The invention relates to a synthesis method of diboron azatriphenylene and a derivative thereof, tests the photoelectric physical properties of the compounds and further researches potential application values of the organic materials on the aspect of organic electrochemistry. The compound has a structural formula as shown in the specification, wherein each of R1, R2, R3, R4, R5, R6, R7 and R8 isan independent substituted or non-substituted group and comprises an alkyl and an aryl (a benzene ring, a thiophene ring, a furan ring, pyrrole, pyridine, benzothiophene, benzofuran, benzopyrrole, benzopyridine, a naphthalene ring, an anthracene ring, phenalene, naphthacene, pyrene, jue as shown in the specification, linear or angular pentacene, hexacene, indene, fluorene and the like), wherein R1, R2, R3 and R4 may also be single substituted halogen atom X: F, Cl, Br and I.

The invention discloses a preparation method of ready-to-eat beef steak, which comprises the following steps: unfreezing pre-frozen originally cut beef steak, wiping redundant blood on the surface of the unfrozen beef steak by using absorbent paper, then placing the beef steak in a superheated steam tray, then carrying out superheated steam treatment on the beef steak, rapidly cooling, and then loading into a sterile bag, and performing water bath sterilization, and finally performing vacuum-pumping treatment to obtain the instant beef steak. No additive is added in the making process of the beef steak, the beef steak is sterilized while the fragrance of the beef steak is increased through heat treatment, the content of benzopyrene generated by the method is lower than that of benzopyrene generated by other methods, and harm of microorganisms is effectively reduced through secondary sterilization on the basis. According to the scheme, the produced benzopyrrole is effectively reduced and is far lower than the national standard 5.0 mu g/kg, and the steak is tough and tender in taste, good in aroma stability and comprehensive in nutrition.

The invention relates to a 6-flourine-3a-(trifluoromethyl)-2,3,3a,4-tetrahydro-1H-benzo[d]pyrrole[1,2-a]imidazole-1-ketone and a method for synthesizing the same. The structural formula of the compound is shown as a right formula. The method comprises the following steps that: trifluoro gamma-keto acid methyl ester and toluene sulfonic acid are dissolved in toluene and added with anhydrous magnesium sulfate in catalyst amount, and the mixture is subjected to refluxing reaction for 20 to 60 minutes in stirring, and then added with fluorine o-phenylendiamine; the mixture is continuously reacted for 10 to 15 hours and then added with toluene sulfonic acid in catalyst amount; the mixture is subjected to refluxing reaction for 10 to 15 hours; after the reaction, the mixture is separated and purified to obtain a white solid which is the 6-flourine-3a-(trifluoromethyl)-2,3,3a,4-tetrahydro-1H-benzo[d]pyrrole[1,2-a]imidazole-1-ketone; and the molar ratio of the trifluoro gamma-keto acid methyl ester to the fluorine o-phenylendiamine is 1-1.2:1. The 6-flourine-3a-(trifluoromethyl)-2,3,3a,4-tetrahydro-1H-benzo[d]pyrrole[1,2-a]imidazole-1-ketone has stronger activity and is absorbed more easily. Moreover, the method has the advantages of easily bought raw materials, quite simple operation, synthesis by a one-pot method, 58 percent of yield and suitability for mass production.

The invention relates to 3a-(trifluoromethyl)-3,3a-dihydrobenzene[d]pyrrole[2,1-b]oxazole-1(2H)-ketone and a synthesis method thereof. The structural formula of the compound is shown as right. The method comprises the following steps: dissolving trifluoro gamma-methyl keto ester and catalytic dosage of paratoluenesulfonic acid into toluene, adding catalytic dosage of anhydrous magnesium sulfate, carrying out reflux reaction on the mixture for 20 to 60 minutes with stirring, and then adding ortho-aminophenol; adding the catalytic dosage of paratoluenesulfonic acid after reacting for 10 to 15 hours, performing reflux reaction for 10 to 15 hours, and ending the reaction; and performing separation and purification to obtain a white solid, namely 3'-trifluoromethyl-1-benzopyrrole ketopyrrolidine derivative. The 3a-(trifluoromethyl)-3,3a-dihydrobenzene[d]pyrrole[2,1-b]oxazole-1(2H)-ketone creatively introduces a fluoridebearing group of trifluoromethyl with electron absorbing function to 3a position of benzopyrrole ketopyrrolidine so as to enhance the activity and be favorable for absorbing. In the invention, raw materials are easy to obtain, the operation is simple, the product is synthesized by a one-pot method, the productivity is up to 71 percent, and the product is suitable to be produced on a large scale.

The invention provides a deep-color near-infrared-transmitting polypropylene compound and a preparation method thereof. The deep-color near-infrared-transmitting polypropylene compound comprises the following components: 98-99 parts of polypropylene resin; 0.2-0.8 part of a nucleating agent; 0.2-0.8 part of an organic pigment; and 0-2 parts of other additives. According to the polypropylene compound, the nucleating agent is added, so that in the crystallization process of a polypropylene material, the spherical crystal size is reduced through the heterogeneous nucleation effect, refraction and reflection of visible light and light waves in a near-infrared region are reduced, and thereby a high light transmission effect is achieved; meanwhile, the phthalocyanine pigment molecules are planar macrocyclic conjugated systems composed of four isoindole units; and indole is also called benzopyrrole and has similar results with DPP and has little influence on infrared light transmittance, so that by compounding the several pigments, a dark-color material can be prepared, wherein the material molecules have very excellent infrared transmittance and can be widely applied to the field of household appliance remote control.

The invention discloses a novel organic electroluminescent material based on benzopyrroledione and application thereof. Benzopyrroledione is used as a skeleton, and a type of fused ring molecules with a larger conjugate plane are constructed through cyclization and other series reactions, so that the non-radiative transition of the molecules is reduced, and the luminous efficiency of the material is improved; electron donating groups and electron withdrawing groups are further introduced into the molecules to regulate and control the photophysical properties of the material; and an organic light-emitting device is prepared through a solution method by taking the material as a light-emitting layer doping agent, and the maximum external quantum efficiency (2.2%) is obtained.

The invention discloses a high-efficiency high-temperature-resistant proton conduction material and a preparation method thereof, and relates to the technical field of proton conduction materials. The preparation method comprises the following steps: firstly, mixing trimalonic acid (triphenylmethoxy) silane and 4, 5-diamino-o-chloro-sulfurized benzoyl chloride to form a thioxanthone microporous polymer, and preparing high-temperature-resistant nano gel particles; the preparation method comprises the following steps: preparing nano gel particles, mixing tri-o-aminobenzoquinonyl benzene, 2-sulfydryl-3-carbonyl-4-nitrobutanol and the nano gel particles to form a benzopyrrole compound, forming hyperbranched amide through a photosynthesis-assisted ultrasonic process, and stably embedding the nano gel particles in a cavity of the hyperbranched amide to obtain the hyperbranched polymer. And the density of sulfonate ions in the mass transfer channel is increased during use, so that the prepared high-efficiency high-temperature-resistant proton conduction material has good high temperature resistance, tensile strength, conductivity and proton conductivity.

The invention relates to a plurality of Ulllazine derivatives containing diarylboron and diarylamine and a synthesis method thereof. The photoelectric material quantity properties of the compounds aretested, and the potential application values of the compounds in the aspect of organic photoelectricity are further studied. The structural formulas of the compounds are shown in the description, wherein R1 groups are independent and can be single substituted halogen atoms X: F, Cl, Br and I, or hydrogen, olefin, alkyne, alkyl, aldehyde group or ketone, or substituted or unsubstituted aryl and heteroaryl (benzene ring, thiophene ring, furan ring, pyrrole, pyridine, benzothiophene, benzofuran, benzopyrrole, benzopyridine, naphthalene ring, anthracene ring, phenalene, tetracene, pyrene, chrysene, linear or angled pentacene, hexacene, indene, fluorene and the like), or a diarylboron group or a diarylamine group, Ar1 and Ar2 represent different types of aryl groups (benzene ring, thiophene ring, furan ring, pyrrole, pyridine, benzothiophene, benzofuran, benzopyrrole, benzopyridine, naphthalene ring, anthracene ring, phenadiene, tetracene, pyrene, chrysene, linear or angled pentacene, hexacene, indene, fluorene and the like).